Photoelectrochemical enzymatic penicillin biosensor: A proof-of-concept experiment

  • Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors thatutilizelighttoprovideinformationaboutthecompositionofananalyte,enablinglight-controlled multi-analyte measurements. For enzymatic PEC biosensors,amperometric detection principles are already known in the literature. In con-trast, there is only a little information on H+-ion sensitive PEC biosensors. Inthis work, we demonstrate the detection of H+ions emerged by H+-generatingenzymes, exemplarily demonstrated with penicillinase as a model enzyme on atitanium dioxide photoanode. First, we describe the pH sensitivity of the sensorand study possible photoelectrocatalytic reactions with penicillin. Second, weshow the enzymatic PEC detection of penicillin.

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Metadaten
Author:Rene Welden, Cindy A. Nagamine Komesu, Patrick H. Wagner, Michael Josef SchöningORCiD, Torsten WagnerORCiD
DOI:https://doi.org/10.1002/elsa.202100131
ISSN:2698-5977
Parent Title (English):Electrochemical Science Advances
Publisher:Wiley-VCH
Place of publication:Weinheim
Document Type:Article
Language:English
Year of Completion:2021
Date of the Publication (Server):2022/03/29
Tag:enzymatic biosensor; penicillin; penicillinase; photoelectrochemistry; titanium dioxide photoanode
Volume:2
Issue:4
First Page:1
Last Page:5
Note:
Corresponding auhtor: Michael J. Schöning
Link:https://doi.org/10.1002/elsa.202100131
Zugriffsart:weltweit
Institutes:FH Aachen / Fachbereich Medizintechnik und Technomathematik
FH Aachen / INB - Institut für Nano- und Biotechnologien
collections:Verlag / Wiley-VCH
Open Access / Gold
Licence (German):License LogoCreative Commons - Namensnennung