Photoelectrochemical enzymatic penicillin biosensor: A proof-of-concept experiment
- Photoelectrochemical (PEC) biosensors are a rather novel type of biosensors thatutilizelighttoprovideinformationaboutthecompositionofananalyte,enablinglight-controlled multi-analyte measurements. For enzymatic PEC biosensors,amperometric detection principles are already known in the literature. In con-trast, there is only a little information on H+-ion sensitive PEC biosensors. Inthis work, we demonstrate the detection of H+ions emerged by H+-generatingenzymes, exemplarily demonstrated with penicillinase as a model enzyme on atitanium dioxide photoanode. First, we describe the pH sensitivity of the sensorand study possible photoelectrocatalytic reactions with penicillin. Second, weshow the enzymatic PEC detection of penicillin.
| Author: | Rene Welden, Cindy A. Nagamine Komesu, Patrick H. Wagner, Michael Josef SchöningORCiD, Torsten WagnerORCiD |
|---|---|
| DOI: | https://doi.org/10.1002/elsa.202100131 |
| ISSN: | 2698-5977 |
| Parent Title (English): | Electrochemical Science Advances |
| Publisher: | Wiley-VCH |
| Place of publication: | Weinheim |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2021 |
| Date of the Publication (Server): | 2022/03/29 |
| Tag: | enzymatic biosensor; penicillin; penicillinase; photoelectrochemistry; titanium dioxide photoanode |
| Volume: | 2 |
| Issue: | 4 |
| First Page: | 1 |
| Last Page: | 5 |
| Note: | Corresponding author: Michael J. Schöning |
| Link: | https://doi.org/10.1002/elsa.202100131 |
| Zugriffsart: | weltweit |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| open_access (DINI-Set): | open_access |
| collections: | Verlag / Wiley-VCH |
| Open Access / Gold | |
| Geförderte OA-Publikationen / DEAL Wiley | |
| Licence (German): |  Creative Commons - Namensnennung |
