Refine
Year of publication
Document Type
- Article (95)
- Conference Proceeding (12)
- Part of a Book (2)
- Report (1)
Keywords
- Light-addressable potentiometric sensor (3)
- LAPS (2)
- light-addressable potentiometric sensor (2)
- Biosensor (1)
- Chemical images (1)
- Chemical imaging (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- EIS capacitive sensor (1)
- Field-effect device (1)
- I3S 2005 (1)
- International Symposium on Sensor Science (1)
- Light-addressable Potentiometric Sensor (1)
- MOS (1)
- Negative impedance convertor (1)
- Organic light-emitting diode display (1)
- Potentiometry (1)
- Resonance-mode measurement (1)
- acetoin (1)
- acetoin reductase (1)
The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17–200 mM) follows a Michaelis–Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.