Article
Refine
Year of publication
- 2024 (16)
- 2023 (59)
- 2022 (75)
- 2021 (80)
- 2020 (93)
- 2019 (95)
- 2018 (83)
- 2017 (72)
- 2016 (78)
- 2015 (83)
- 2014 (93)
- 2013 (96)
- 2012 (80)
- 2011 (128)
- 2010 (119)
- 2009 (119)
- 2008 (102)
- 2007 (94)
- 2006 (86)
- 2005 (99)
- 2004 (131)
- 2003 (74)
- 2002 (92)
- 2001 (88)
- 2000 (84)
- 1999 (88)
- 1998 (82)
- 1997 (79)
- 1996 (70)
- 1995 (68)
- 1994 (76)
- 1993 (51)
- 1992 (48)
- 1991 (25)
- 1990 (35)
- 1989 (38)
- 1988 (54)
- 1987 (32)
- 1986 (18)
- 1985 (32)
- 1984 (18)
- 1983 (17)
- 1982 (26)
- 1981 (18)
- 1980 (35)
- 1979 (23)
- 1978 (30)
- 1977 (14)
- 1976 (13)
- 1975 (10)
- 1974 (3)
- 1972 (2)
- 1971 (1)
- 1968 (1)
Document Type
- Article (3226) (remove)
Language
- English (3226) (remove)
Keywords
- Einspielen <Werkstoff> (7)
- avalanche (5)
- Earthquake (4)
- FEM (4)
- Finite-Elemente-Methode (4)
- LAPS (4)
- biosensors (4)
- field-effect sensor (4)
- frequency mixing magnetic detection (4)
- CellDrum (3)
- Heparin (3)
- Label-free detection (3)
- additive manufacturing (3)
- capacitive field-effect sensor (3)
- hydrogen peroxide (3)
- magnetic nanoparticles (3)
- shakedown analysis (3)
- snow (3)
- tobacco mosaic virus (TMV) (3)
- Acyl-amino acids (2)
Institute
- Fachbereich Medizintechnik und Technomathematik (1343)
- INB - Institut für Nano- und Biotechnologien (501)
- Fachbereich Chemie und Biotechnologie (466)
- IfB - Institut für Bioengineering (408)
- Fachbereich Elektrotechnik und Informationstechnik (401)
- Fachbereich Energietechnik (360)
- Fachbereich Luft- und Raumfahrttechnik (247)
- Fachbereich Maschinenbau und Mechatronik (147)
- Fachbereich Wirtschaftswissenschaften (106)
- Fachbereich Bauingenieurwesen (68)
- Solar-Institut Jülich (43)
- ECSM European Center for Sustainable Mobility (27)
- Sonstiges (21)
- Institut fuer Angewandte Polymerchemie (20)
- Freshman Institute (17)
- Nowum-Energy (16)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (15)
- Fachbereich Gestaltung (12)
- Fachbereich Architektur (9)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (5)
Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.