Refine
Year of publication
- 2018 (59) (remove)
Document Type
- Article (41)
- Part of a Book (8)
- Conference Proceeding (7)
- Book (2)
- Doctoral Thesis (1)
Language
- English (59) (remove)
Keywords
- Bladder (1)
- Chemical imaging (1)
- Coat protein (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Dry surfaces (1)
- Enzyme nanocarrier (1)
- Equivalence test (1)
- Field-effect device (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Goodness-of-fit tests for uniformity (1)
- Growth modelling (1)
- Integrated empirical distribution (survival) function (1)
- Lab-on-Chip (1)
- Light-addressable potentiometric sensor (1)
- Mechanical simulation (1)
- Microbial adhesion (1)
- Muscle fibers (1)
- Numerical inversion of Laplace transforms (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Potentiometry (1)
- Reconstruction (1)
- Rehabilitation Technology and Prosthetics (1)
- Sampling methods (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Swabbing (1)
- Tobacco mosaic virus (TMV) (1)
- Ureter (1)
- achilles tendon (1)
- energy absorption (1)
- energy dissipation (1)
- frequency mixing (1)
- functional data (1)
- huge dimensional data (1)
- magnetic beads (1)
- magnetic sensing (1)
- mechanical buffer (1)
- separable Hilbert space (1)
- stiffness (1)
- superparamagnetic nanoparticles (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (59) (remove)
A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.