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Year of publication
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- Fachbereich Maschinenbau und Mechatronik (876) (remove)
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Frotscher, Ralf ; Goßmann, Matthias ; Raatschen, Hans-Jürgen ; Temiz Artmann, Aysegül ; Staat, Manfred
We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Kennwortgeschützter Zugang nur für Studierende bei Prof. Dr. Klaus-Peter Kämper. Sommersemester 2007. Version 2.3 vom 27.02.2007 I-8, 484 S.: Ill.; graph. Darst. Inhaltsverzeichnis: 1 Einführung: Was ist Mikrotechnik? 2 Fertigung im Reinraum 3 Der Werkstoff Silizium 4 Dünnschichttechnologie 5 Photolithographie 6 Ätztechnologie 7 „Bulk Micromachining“ 8 „Surface Micromachining“ 9 Trockenätzen tiefer Mikrostrukturen 10 LIGA-Technik 11 Mikrofunkenerosion 12 Laser in der Mikrotechnik 13 Mechanische Mikrofertigung 14 Photostruktuierbares Glas 15 Aufbau- und Verbindungstechnik