Refine
Year of publication
- 2014 (304) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (66)
- Fachbereich Chemie und Biotechnologie (47)
- Fachbereich Elektrotechnik und Informationstechnik (43)
- Fachbereich Wirtschaftswissenschaften (41)
- Fachbereich Energietechnik (40)
- INB - Institut für Nano- und Biotechnologien (35)
- IfB - Institut für Bioengineering (25)
- Fachbereich Maschinenbau und Mechatronik (21)
- Fachbereich Luft- und Raumfahrttechnik (13)
- Fachbereich Bauingenieurwesen (12)
- Solar-Institut Jülich (6)
- Fachbereich Architektur (4)
- Sonstiges (3)
- FH Aachen (2)
- Institut fuer Angewandte Polymerchemie (2)
- ECSM European Center for Sustainable Mobility (1)
- Fachbereich Gestaltung (1)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (1)
Document Type
- Article (142)
- Conference Proceeding (67)
- Part of a Book (31)
- Book (22)
- Conference: Meeting Abstract (15)
- Report (8)
- Other (6)
- Bachelor Thesis (3)
- Patent (3)
- Part of a Periodical (2)
Keywords
The impact of wake model effects is investigated for two highly
non-planar lifting systems. Dependent on the geometrical
arrangement of the configuration, the wake model shape is found
to considerably affect the estimation. Particularly at higher angles
of attack, an accurate estimation based on the common linear wake
model approaches is involved.
Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.
A platform technology for the automated reaction control in magnetizable micro-fluidic droplets
(2014)