Article
Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (1356)
- INB - Institut für Nano- und Biotechnologien (503)
- Fachbereich Chemie und Biotechnologie (472)
- Fachbereich Elektrotechnik und Informationstechnik (414)
- IfB - Institut für Bioengineering (409)
- Fachbereich Energietechnik (361)
- Fachbereich Luft- und Raumfahrttechnik (253)
- Fachbereich Maschinenbau und Mechatronik (148)
- Fachbereich Wirtschaftswissenschaften (116)
- Fachbereich Bauingenieurwesen (69)
Language
- English (3275) (remove)
Document Type
- Article (3275) (remove)
Keywords
- Einspielen <Werkstoff> (7)
- avalanche (5)
- Earthquake (4)
- FEM (4)
- Finite-Elemente-Methode (4)
- LAPS (4)
- biosensors (4)
- field-effect sensor (4)
- frequency mixing magnetic detection (4)
- CellDrum (3)
- Heparin (3)
- Label-free detection (3)
- additive manufacturing (3)
- capacitive field-effect sensor (3)
- hydrogen peroxide (3)
- impedance spectroscopy (3)
- magnetic nanoparticles (3)
- shakedown analysis (3)
- snow (3)
- sustainability (3)
- tobacco mosaic virus (TMV) (3)
- Acyl-amino acids (2)
- Aeroelasticity (2)
- Aminoacylase (2)
- Bacillaceae (2)
- Bacillus atrophaeus (2)
- Biotechnological application (2)
- Boundary integral equations (2)
- Brake set-up (2)
- Butanol (2)
- CFD (2)
- Capacitive field-effect sensor (2)
- Chemometrics (2)
- Conductive boundary condition (2)
- Drinfeld modules (2)
- Einspielanalyse (2)
- Empirical process (2)
- Fault detection (2)
- Field-effect sensor (2)
- Freight rail (2)
- Germany (2)
- Goodness-of-fit test (2)
- Hot S-parameter (2)
- IR spectroscopy (2)
- Independence test (2)
- Light-addressable potentiometric sensor (2)
- Lipopolysaccharide (2)
- MINLP (2)
- NMR spectroscopy (2)
- Obstacle avoidance (2)
- Paired sample (2)
- Parametric bootstrap (2)
- Path planning (2)
- Principal component analysis (2)
- Pump System (2)
- Raman spectroscopy (2)
- SLM (2)
- Shakedown analysis (2)
- Simulation (2)
- Standardization (2)
- Stiffness (2)
- Subtilases (2)
- Subtilisin (2)
- Traglastanalyse (2)
- Transcendence (2)
- Transmission eigenvalues (2)
- UAV (2)
- bacterial cellulose (2)
- bubble column (2)
- capacitive field-effect sensors (2)
- carbonized rice husk (2)
- constructive alignment (2)
- damage (2)
- energy efficiency (2)
- examination (2)
- factory planning (2)
- fused filament fabrication (2)
- gold nanoparticles (2)
- harmonic radar (2)
- immobilization (2)
- light-addressable potentiometric sensor (2)
- likelihood ratio test (2)
- limit analysis (2)
- locomotion (2)
- long-term retention (2)
- manufacturing flexibility (2)
- methanation (2)
- microfluidics (2)
- multimodal (2)
- muscle fascicle behavior (2)
- not identically distributed (2)
- penicillinase (2)
- plug flow reactor (2)
- practical learning (2)
- prebiotic (2)
- qNMR (2)
- rapid tooling (2)
- rebound-effect (2)
- shakedown (2)
- t-modules (2)
- ultrasound (2)
- ultrasound imaging (2)
- (Bio)degradation (1)
- (Poly)saccharides (1)
- 197m/gHg (1)
- 1P hub loads (1)
- 3-D printing (1)
- 316L (1)
- 3D nonlinear finite element model (1)
- 802.15.4 (1)
- ABE (1)
- Acceleration (1)
- Achilles tendon (1)
- Acid crash (1)
- Active humidity control (1)
- Actuator disk modelling (1)
- Acylation (1)
- Adaptive control (1)
- Additive Manufacturing (1)
- Additive manufacturing (1)
- Afterload (1)
- Ageing (1)
- Air purification (1)
- Aircraft sizing (1)
- Algal Turf Scrubber (1)
- Algal–bacterial bioflm (1)
- Alginate beads (1)
- Alkalihalobacillus okhensis (1)
- Aloe vera (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Analytischer Zulaessigkeitsnachweis (1)
- Anammox (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Antarctic Glaciology (1)
- Antibias (1)
- Architectural design (1)
- Architectural gear ratio (1)
- Artificial intelligence (1)
- Assembly (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Authenticity (1)
- Autolysis (1)
- Automated driving (1)
- Automatic control (1)
- Automotive application (1)
- Automotive safety approach (1)
- Autonomy (1)
- Avalanche (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- BET (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Balance (1)
- Balanced hypergraph (1)
- Bank-issued Warrants (1)
- Basis Reduktion (1)
- Basis reduction (1)
- Bauingenieurwesen (1)
- Behaviour factor q (1)
- Benchmark (1)
- Bicharakteristikenverfahren (1)
- Bio-inspired systems (1)
- Bioabsorbable (1)
- Biocatalysis (1)
- Biocomposites (1)
- Biofuel (1)
- Biogas (1)
- Biological hydrogen (1)
- Biomass (1)
- Biomechanical simulation (1)
- Bioreaktor (1)
- Biorefinery (1)
- Biosolubilization (1)
- Biosurfactants (1)
- Blade element method (1)
- Bloom’s Taxonomy (1)
- Bluetooth (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Booster Station (1)
- Booster Stations (1)
- Bootstrap (1)
- Bootstrapping (1)
- Borehole heat exchanger (1)
- Boundary integral equations, (1)
- Bragg peak (1)
- Brake test (1)
- Braking curves (1)
- Brands (1)
- Broad pH spectrum (1)
- Brownian Pillow (1)
- Buffering Capacity (1)
- C. acetobutylicum (1)
- CAD (1)
- CAV (1)
- CFD propeller simulation (1)
- CNOT (1)
- CO2 emission reduction targets (1)
- CRISPR/Cas9 (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Cardiovascular MRI (1)
- Cardiovascular Magnetic Resonance (1)
- Carrier solvents (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Censored data (1)
- Centrifugal twisting moment (1)
- Chance Constraint (1)
- Change (1)
- Chaperone (1)
- Chaperone co-expression (1)
- Charging station (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Chondroitin sulfate (1)
- Circuit simulation (1)
- Circular Dichroism (1)
- Circular bioeconomy (1)
- Civil engineering (1)
- Clinical decision support systems (1)
- Clostridium acetobutylicum (1)
- Clusterion (1)
- Co-managed care (1)
- Collective risk model (1)
- Commercial Vehicle (1)
- Common Rail Injection System (1)
- Competence Developing Games (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conductive Boundary Condition (1)
- Consensus (1)
- Conservation laws (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Convex optimization (1)
- Cost function (1)
- Cost-effectiveness (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Crashworthiness (1)
- Cross border adjustment mechanism (1)
- Crude heparin (1)
- Crámer–von-Mises distance (1)
- Culture media (1)
- Cyclotron production (1)
- C–V method (1)
- DAC (1)
- DLR-ESTEC GOSSAMER roadmap for solar sailing (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Dark fermentation (1)
- Decomposition (1)
- Decoupling (1)
- Deformation (1)
- Dehydrogenase (1)
- Design-by-analysis (1)
- Detergent protease (1)
- Deuterated solvents (1)
- Deuterium NMR (1)
- Diaphorase (1)
- Diesel Engine (1)
- Dietary supplements (1)
- Dimensional splitting (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discourse ethics (1)
- Discrete Optimization (1)
- Disposition Effect (1)
- Distributed Control Systems, (1)
- Diversity Management (1)
- Drag estimation (1)
- Driver assistance system (1)
- Driving cycle recognition (1)
- Druckbeanspruchung (1)
- Druckbehälter (1)
- Druckbelastung (1)
- Druckgeräte (1)
- Drug simulation (1)
- Dry-low-NOx (DLN) combustion (1)
- Duality (1)
- Dynamic simulation (1)
- E-Mobility (1)
- E. coli detection (1)
- ECMS (1)
- EGG (1)
- EIS capacitive sensor (1)
- ELISA (1)
- ES-FEM (1)
- Effective modal mass (1)
- Eigenvalue trajectories (1)
- Einspiel-Analyse (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastizität (1)
- Elderly (1)
- Electrochemical impedance spectroscopy (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Electronic cigarettes (1)
- Electronic vehicle (1)
- Elemental (1)
- Emilia-Romagna earthquake (1)
- Empirical consequence curves (1)
- Empirical fragility functions (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Energy management strategies (1)
- Energy-intensive industry (1)
- Engineering Application (1)
- Engineering Habitus (1)
- Enterprise information systems (1)
- Entropy solution (1)
- Environmental impact (1)
- Enzymatic biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme-linked immunosorbent assay (1)
- Epithel (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- European Transient Cycle (1)
- Eutectic Silver Copper alloy (1)
- Experiment (1)
- Experimental validation (1)
- Explainability (1)
- Exponential Euler scheme, (1)
- Exponential time differencing (1)
- Extension–twist coupling (1)
- External knee adduction moments (1)
- Extracellular enzymes (1)
- Extraterrestrial Glaciology (1)
- FS-FEM (1)
- Fall prevention (1)
- Fault approximation (1)
- Feature selection (1)
- Fehlerstellen (1)
- Fibroblast (1)
- Field effect (1)
- Field-effect biosensor (1)
- Finite difference methods (1)
- Finite differences (1)
- Finite element analysis (1)
- Finite element method (1)
- Finite element modelling (1)
- Finland (1)
- Fließgrenze (1)
- Floor prices (1)
- Flutter (1)
- Force (1)
- Forces (1)
- Fracture classification (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Frame structure (1)
- Free-base nicotine (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Fuel cell (1)
- Full-vehicle crash test (1)
- Functional Delta Method (1)
- Furnace (1)
- Fusion (1)
- GOSSAMER-1 (1)
- Ga-68 (1)
- Game-based learning (1)
- Gamification (1)
- Gamma distribution (1)
- Genetic algorithm (1)
- Geriatric (1)
- German (1)
- Glaciological instruments and methods (1)
- Glaucoma (1)
- Global and local collapse (1)
- Glucosamine (1)
- Gold nanoparticle (AuNP) (1)
- Gold nanoparticles (1)
- Goodness-of-fit tests for uniformity (1)
- Grenzwertberechnung (1)
- Ground-level falls (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Hall’s Theorem (1)
- Halotolerant protease (1)
- Handbike (1)
- Harnleiter (1)
- Hazard assessment (1)
- Health management system (1)
- Heart tissue culture (1)
- Heat transport (1)
- Helmholtz equation (1)
- Hemoglobin structure (1)
- Heterostructure (1)
- High field MRI (1)
- High hydrogen combustion (1)
- High-field NMR (1)
- Higher derivations (1)
- Higher-order codes (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Human Development Index (1)
- Human factors (1)
- Human-Computer interaction (1)
- Hydrogen combustion (1)
- Hydrogen gas turbine (1)
- Hydrogen peroxide (1)
- Hydrolysis (1)
- Hyperdifferentials (1)
- Hypergraph (1)
- Hypersecretion (1)
- Hämoglobin (1)
- Hämoglobinstruktur (1)
- INSYSME (1)
- IP-based networks (1)
- IR (1)
- IT security education (1)
- Illustration (1)
- Image Quality Assessment (1)
- Image Quality Score (1)
- Image Reconstruction (1)
- Imaging (1)
- Impedance analysis (1)
- Impedance spectroscopy (1)
- Implicit methods (1)
- In-plane performance, isolation (1)
- Incident analysis (1)
- Inclusion bodies (1)
- Incomplete data (1)
- Individual Investors (1)
- Induced pluripotent stem cells (1)
- Industrial Automation Technology, (1)
- Infill wall design (1)
- Information extraction (1)
- Inorganic ions (1)
- Inotropic compounds (1)
- Instructional design (1)
- Integrated empirical distribution (survival) function (1)
- Interior Neumann eigenvalues (1)
- Interior transmission eigenvalues (1)
- Interior transmission problem (1)
- Interstellar objects (1)
- Interval Time Series (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering (1)
- Inverse scattering problem (1)
- Inverse spectral problem (1)
- Ion channels (1)
- Ions (1)
- Iterative learning control (1)
- Justice (1)
- Keyword analysis (1)
- Kinetic energy (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Koenig’s Theorem (1)
- Kohlenstofffaser (1)
- LPBF (1)
- LPS (1)
- Lab-on-Chip (1)
- Lactobacillus rhamnosus GG (1)
- Landslide tsunamis (1)
- Langevin theory (1)
- Large scale tests (1)
- Larynx position (1)
- Latvia (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Left ventriular function (1)
- Level system (1)
- Li7La3Zr2O12 (1)
- LiGaO2 (1)
- Lidar (1)
- Lifting propeller (1)
- Light-addressable Potentiometric Sensor (1)
- Lignocellulose (1)
- Limit analysis (1)
- Linear discriminant analysis (1)
- Linear elastic analysis (1)
- Liver (1)
- Local path planning (1)
- Long COVID (1)
- Low field NMR (1)
- Low-field NMR (1)
- Luftreiniger (1)
- Luxury (1)
- MCDA (1)
- MILP (1)
- MOS (1)
- MR safety (1)
- MR-stethoscope (1)
- MRI (1)
- MST (1)
- MUT measurement; scanner (1)
- Machine learning (1)
- Magnetic field strength (1)
- Magnetic nanoparticles (1)
- Magnetic resonance imaging (MRI) (1)
- Magneto alert sensor (1)
- Mainstream (1)
- Manipulated variables (1)
- Manufacturer (1)
- Marginal homogeneity test (1)
- Marker-free mutagenesis (1)
- Masonry infill (1)
- Masonry partition walls (1)
- Master stamp (1)
- Matching (1)
- Materialermüdung (1)
- Matrix exponential (1)
- Measurement models (1)
- Measurement uncertainty (1)
- Mechanotransduction (1)
- Medical AI (1)
- Medical radionuclide production (1)
- Medusomyces gisevi (1)
- Meitner-Auger-electron (MAE) (1)
- Metabolic shift (1)
- Metal contaminants (1)
- Metascintillator (1)
- Methane (1)
- Microcirculation (1)
- Microfluidic solvent extraction (1)
- Micromagnetic simulation (1)
- Micromix combustion (1)
- Mikrosystemtechnik (1)
- Mild cognitive impairment (1)
- Missions (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Mode converter (1)
- Model-driven software engineering (1)
- Modelica (1)
- Modeling (1)
- Modelling (1)
- Modern constructions (1)
- Molecular modelling (1)
- Molecular weight determination (1)
- Molten salt receiver system (1)
- Molten salt solar tower (1)
- Monotone methods (1)
- Monte Carlo Tree Search (1)
- Morphing (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional partial differential equations (1)
- Multi-objective optimization (1)
- Multi-sample problem (1)
- Multi-storey (1)
- Multianalyte detection (1)
- Multicell (1)
- Multiple TOF kernels (1)
- Multiplexing (1)
- Multirotor UAS (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NGN (1)
- NMR (1)
- NMR exchange relaxometry (1)
- NONOate (1)
- Natural fibres (1)
- Natural frequency (1)
- Negative Feedback Trading (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Nitrogen removal (1)
- Non-model-based Evaluation (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nonlinear PDEs (1)
- Nonlinear eigenvalue problems (1)
- Normative standards (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- Numerical modelling (1)
- Numerics (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Online diagnostic (1)
- Operations (1)
- Organic acids (1)
- Organic light-emitting diode display (1)
- Organic waste (1)
- Organizational Culture (1)
- Organkultur (1)
- Osteoporose (1)
- Osteoporosis (1)
- Out-of-plane capacity (1)
- Overland flow (1)
- P2G (1)
- PBEE (1)
- PEM fuel cell (1)
- PIV (1)
- PLS-regression (1)
- PROFINET (1)
- Parabolic SPDEs (1)
- Paralympic sport (1)
- Parasitic drag (1)
- Parking (1)
- Partial nitritation (1)
- Penicillin (1)
- Periods (1)
- Permeability (1)
- Permeabilität (1)
- Peroxidase (1)
- Pflanzenphysiologie (1)
- Pflanzenscanner (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Photolithographic mimics (1)
- Physiology (1)
- Piping (1)
- Plant virus (1)
- Plasma (1)
- Plasma diagnostics (1)
- Plasmacluster ion technology (1)
- Plastizität (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Polymer-matrix composites (1)
- Polysaccharides (1)
- Porositat (1)
- Post-COVID-19 syndrome (1)
- Potential theory (1)
- Powertrain (1)
- Pre-culture (1)
- Precast buildings (1)
- Predictive battery discharge (1)
- Preference assessment (1)
- Pressure loaded crack-face (1)
- Pretreatment (1)
- Prevention (1)
- Probability distribution mapping (1)
- Process virtualization (1)
- Product bundling (1)
- Product-integration (1)
- Progressive plastic deformation (1)
- Propeller (1)
- Propeller aerodynamics (1)
- Propeller elasticity (1)
- Propeller performance (1)
- Propeller whirl flutter (1)
- Proper Orthogonal Decomposition (1)
- Prophylaxis (1)
- Proximal humerus fracture (1)
- Pulsations (1)
- Pumping systems (1)
- Q-criterion (1)
- Quality control (1)
- Quantum chemistry (1)
- Quartz crystal microbalance (1)
- RAMMS (1)
- RVA (1)
- Radar (1)
- Rapid Prototyping (1)
- Rapid Technologie (1)
- Rapid prototyping (1)
- Ratchetting (1)
- Raumluft (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Red blood cell storage (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Reinforced concrete frame (1)
- Relative air humidity (1)
- Requirements prioritization (1)
- Requirements relations (1)
- Resampling test (1)
- Reservation system (1)
- Resistive temperature detector (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Response Surface Method (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Robotic rehabilitation (1)
- Rohr (1)
- Rohrbruch (1)
- Rotary encoder (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- SFCW (1)
- SOA (1)
- SSE) JEL : O33 (1)
- ScaLAPACK (1)
- Schwammknochen (1)
- Seismic design (1)
- Seismic loading (1)
- Selective Catalytic Reduction (1)
- Self-driving (1)
- Semi-parametric random censorship model (1)
- Septic cardiomyopathy (1)
- Services (1)
- Shakedown (1)
- Shakedown criterion (1)
- Shoulder (1)
- Shunting (1)
- Silk fibroin (1)
- Simultaneous determination (1)
- Skeletal muscle (1)
- Slab deflection (1)
- Small Aral Sea (1)
- Small spacecraft (1)
- Snow (1)
- Sn₃O₄ (1)
- Soft independent modeling of class analogy (1)
- Software and systems modeling (1)
- Solar sail (1)
- Solitary waves (1)
- Sound Pressure Level (1)
- Source term (1)
- Spectroscopy (1)
- Spleen (1)
- Stahl (1)
- Steel industry (1)
- Stenotrophomonas maltophilia (1)
- Sterilisation process (1)
- Stochastic Programming (1)
- Streptomyces griseus (1)
- Streptomyces lividans (1)
- Stress concentrations (1)
- Structural design (1)
- Strukturanalyse (1)
- Subclacial exploration (1)
- Subglacial lakes (1)
- Surface imprinted polymer (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Suspension bridge (1)
- TMV adsorption (1)
- TOF PET (1)
- Tank (1)
- Targeted radionuclide therapy (TRT) (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (1)
- Technical Operations Research (TOR) (1)
- Telecommunication (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Thermal conductivity (1)
- Thin shell finite elements (1)
- Tinetti test (1)
- Tissue Engineering (1)
- Tobacco mosaic virus (TMV) (1)
- Tomography (1)
- Tool support (1)
- Trading Behavior (1)
- Traglast (1)
- Train composition (1)
- Trajectories (1)
- Transfer impedance (1)
- Transformation (1)
- Transient flux distribution (1)
- Transmission Eigenvalues (1)
- Trapeze effect (1)
- Two-phase modelling (1)
- Typographie (1)
- USP (1)
- Uktrahigh field MRI (1)
- Ultrasound (1)
- Uncertainty (1)
- Uniaxial compression test (1)
- Unmanned aerial vehicles (1)
- Unreinforced masonry buildings (1)
- Unsteady aerodynamics (1)
- Uracil-phosphoribosyltransferase (1)
- User study (1)
- Utilization improvement (1)
- VM (1)
- VOF (1)
- VOP compression (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Vertex cover (1)
- Vibrio natriegens (1)
- Virtual reality (1)
- Virtuelle Maschine (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Voice assessment (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Wastewater (1)
- Water Distribution (1)
- Water Supply Networks (1)
- Weak organic acids (1)
- Wiegand sensor (1)
- Wind milling (1)
- Wind tunnel experiments (1)
- Wireless Networks (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Wundheilung (1)
- XOR (1)
- Zeta potential (1)
- Zug-Druck Belastung (1)
- acetoin (1)
- acetoin reductase (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- actuator-sensor system (1)
- adaptive systems (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- alcoholic beverages (1)
- allocation (1)
- alternierend Verformbarkeit (1)
- aminooctanethiol (1)
- amperometric biosensors (1)
- anaesthetic complications (1)
- anammox (1)
- anisotropy (1)
- annealing (1)
- aortic perfusion (1)
- aquaculture (1)
- aromatic amines (1)
- artificial intelligence (1)
- artificial olfactory image (1)
- aseptic parameters (1)
- aspergillus (1)
- assistance system (1)
- asymptotic relative efficiency (1)
- atomic layer deposition (1)
- automated vehicles (1)
- automotive (1)
- autonomous navigation (1)
- availability (1)
- barium strontium titanate (1)
- batteries and fuel cells (1)
- bi-enzyme biosensor (1)
- biaxial tensile experiment (1)
- bicharacteristics (1)
- bio-methane (1)
- bioavailability (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biodegradable polymers (1)
- biofilms (1)
- biological dosimeter (1)
- biomechanics (1)
- biomethane (1)
- biopotential electrodes (1)
- biosensor (1)
- body imaging at 7 T MRI (1)
- body imaging at UHF MRI (1)
- body limbs (1)
- bone density (1)
- bone structure (1)
- bootstrap (1)
- borefields (1)
- borehole disposal (1)
- brachytherapy (1)
- building energy modelling (1)
- building energy simulation (1)
- burst pressure (1)
- burst tests (1)
- business culture (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- cancellous bone (1)
- capacitive EIS sensor (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive model (1)
- carbon dioxide removal (1)
- carbon electrodes (1)
- cardiac gating (1)
- cardiomyocyte biomechanics (1)
- cardiovascular MR imaging (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- change (1)
- change management (1)
- chemical sensor (1)
- chip-based sensor setup (1)
- churches (1)
- civil engineering (1)
- climate change (1)
- climate neutrality (1)
- coculture (1)
- cognitive impairment (1)
- coherent structures (1)
- colorization (1)
- community dwelling (1)
- complete block symmetry (1)
- compression behavior (1)
- computational fluid dynamics analysis (1)
- concentrating collector (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connected automated vehicles (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- control gate (1)
- corporate sustainability (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- critical (1)
- crop yield (1)
- crystallization (1)
- cyber-physical production systems (1)
- dam-break (1)
- debris flow (1)
- deficit irrigation (1)
- dental trauma (1)
- deserts (1)
- design of technical systems (1)
- detection of charged macromolecules (1)
- detergent protease (1)
- dialysis (1)
- difficult airway (1)
- digital factory (1)
- digital twin (1)
- direct air capture (1)
- direct method (1)
- disposal facility (1)
- distorted element (1)
- distribution grid simulation (1)
- diversity management (1)
- double-lumen tube intubation (1)
- drag force (1)
- drop jump (1)
- drug metabolising enzymes (1)
- drug–drug interactions (1)
- e-mobility (1)
- eVTOL development (1)
- eVTOL safety (1)
- earthquake engineering (1)
- ecological structure (1)
- economics (1)
- efficiency side-effects (1)
- eigensolvers (1)
- elastic scattering (1)
- elastic solids (1)
- elastomers (1)
- electrical conductivity of liquids (1)
- electrocardiogram (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electrolyte-insulator-semiconductor capacitors (1)
- electromyography (1)
- electronic nose (1)
- electrospinning (1)
- encapsulation materials (1)
- endoluminal (1)
- endospores (1)
- energy (1)
- energy absorption (1)
- energy dissipation (1)
- energy transfer (1)
- engineering (1)
- entrepreneurship education (1)
- enzymatic (bio)degradation (1)
- enzymatic biosensor (1)
- enzyme cascade (1)
- enzyme kinetics (1)
- enzyme-logic gate (1)
- epithelization (1)
- equivalent circuit (1)
- equivalent stiffness (1)
- event-based simulation (1)
- exchangeability test (1)
- exopolysaccharides (1)
- experimental evaluation (1)
- extracorporeal membrane oxygenation (1)
- eye movement modelling examples (1)
- fatigue analyses (1)
- fibers (1)
- fibroin (1)
- field-effect structure (1)
- filamentous fungi (1)
- flaw (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- frequency mixing (1)
- fuel cell vehicle (1)
- functional data (1)
- ga-doping (1)
- gait (1)
- gamification (1)
- garnet solid electrolyte (1)
- gas sensor (1)
- gaseous hydrogen peroxide (1)
- genetic algorithm (1)
- genome engineering (1)
- geological disposal (1)
- geothermal (1)
- global optimization (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- glycine (1)
- goodness-of-fit test (1)
- granular silo (1)
- graphene oxide (1)
- grey energy (1)
- halotolerant protease (1)
- harmonic radar tags (1)
- healthy aging (1)
- heat demand (1)
- heat transfer coefficient (1)
- heating system (1)
- heavy metals (1)
- hiPS cardiomyocytes (1)
- high field MR imaging (1)
- high-alkaline subtilisin (1)
- high-intensity exercise (1)
- high-k material (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- human dermal fibroblasts (1)
- human metabolites (1)
- humic acid (1)
- hydraulic modelling (1)
- hydrogel (1)
- hydrogels (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- hypoplasticity (1)
- ignition (1)
- impulsive effects (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- incontinence (1)
- independence test (1)
- industrial agents (1)
- industry 4.0 (1)
- infill strategy (1)
- innovation management (1)
- integrated transmit coil arrays (1)
- intelligent control (1)
- intelligent energy management (1)
- intraclass correlation coefficient (1)
- irradiation (1)
- jevons paradox (1)
- key performance indicators (1)
- konvexe Optimierung (1)
- lable-free detection (1)
- large language models (1)
- large-scale inspection (1)
- layer-by-layer technique (1)
- legal obligations (1)
- light-addressable electrode (1)
- light-addressing technologies (1)
- lignite (1)
- limit load (1)
- lipopolysaccharide (1)
- lipopolysaccharides (1)
- liquid-storage tank (1)
- liquid-structure interaction (1)
- literature (1)
- lizards (1)
- load limit (1)
- low-rank coal (1)
- machine learning (1)
- macro-element (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic relaxation (1)
- magnetic resonance imaging (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic sensors (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- mainstream deammonification (1)
- management (1)
- manufacturing (1)
- manufacturing data model (1)
- marketing (1)
- mathematical optimization (1)
- mechanical buffer (1)
- mechanical properties (1)
- metagenomics (1)
- metal-oxide-semiconductor structure (1)
- method of fundamental solutions (1)
- microbial diversity (1)
- micromagnetic simulation (1)
- micronutrients (1)
- microplasma (1)
- microwave (MW) plasma (1)
- microwave measurements (1)
- mix flexibility (1)
- mixed-integer linear programming (1)
- mobile manipulation (1)
- model performance (1)
- motivation (1)
- multi-agent systems (1)
- multi-functional material (1)
- multi-sensing platform (1)
- multianalyte detection (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multiplex detection (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- nanomaterials (1)
- nanoparticle coverage (1)
- nanostructured carbonized plant parts (1)
- nanostrukturierte carbonisierte Pflanzenteile (1)
- naphtols (1)
- negative emissions (1)
- neutrons (1)
- next generation network (1)
- nitrogen elimination (1)
- non-simplex S-FEM elements (1)
- nonlinear VNA measurements (1)
- nonlinear radar (1)
- nonlinear transient analyses (1)
- novel photoexcitation method (1)
- nuclear waste (1)
- numerical model (1)
- on-chip integrated addressable EISCAP sensors (1)
- onion (1)
- optical fibers (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- optimization (1)
- optimization system (1)
- organosilanes (1)
- overload (1)
- oxidative stable protease (1)
- pH sensors (1)
- parabolic flight (1)
- penicillin (1)
- performance analysis (1)
- performance testing (1)
- phenols (1)
- phonocardiogram (1)
- photoelectrochemistry (1)
- physical model (1)
- physiology (1)
- pipes (1)
- plant scanner (1)
- plant stress (1)
- plant virus detection (1)
- plasma jet (1)
- plug-based microfluidic device (1)
- point-focussing system (1)
- poly(d, l-lactic acid) (1)
- polyaniline (1)
- polyaspartic acid (1)
- polyetheretherketone (1)
- polyetheretherketone (PEEK) (1)
- polystyrene sulfonate (1)
- porous materials (1)
- portfolio risk (1)
- power-to-gas (1)
- prevention (1)
- product bundling (1)
- product liability (1)
- production planning and control (1)
- programming (1)
- prostate cancer (1)
- prostatectomy (1)
- proton therapy (1)
- protons (1)
- psychosocial (1)
- pullulan (1)
- quality of life (1)
- random effects (1)
- random effects meta-regression model (1)
- ratchetting (1)
- raytracing (1)
- recombinant expression (1)
- rehabilitation (1)
- relative dosimetry (1)
- reliability analysis (1)
- reliability of structures (1)
- remote sensing (1)
- research association (1)
- resilience (1)
- resource abundance (1)
- retention time (1)
- retinal microvasculature (1)
- retinal vessels (1)
- review (1)
- rollout (1)
- rubber (1)
- running (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- seismic response (1)
- semantic role labeling (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- service-oriented architectures (1)
- shakedown analyses (1)
- shotgun sequencing (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- sizing (1)
- slum classification (1)
- smart-charging (1)
- smooth muscle contraction (1)
- socio-economic welfare (1)
- soil amendment (1)
- soil health (1)
- soil remediation (1)
- solar process heat (1)
- solid-state battery (1)
- spatial resolution (1)
- speaker attribution (1)
- spore kill rate (1)
- sprint start (1)
- standard error of measurement (1)
- sterilisation (1)
- sterility (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stiffness (1)
- stochastic optimization (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- structure-soil-structure interaction (1)
- superabsorbent polymers (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- supramolecular structures (1)
- surface functionalization (1)
- surface modification (1)
- surface-orthogonal path planning (1)
- survival (1)
- swelling properties (1)
- swimming (1)
- system optimization (1)
- system synthesis (1)
- systematic (1)
- technical operations research (1)
- technology planning (1)
- telecommunication (1)
- temperature (1)
- tendon rupture (1)
- tension–torsion loading (1)
- test-retest reliability (1)
- theory and modeling (1)
- thermal dose (1)
- thermal ratcheting (1)
- thermometry (1)
- tilted constant illumination (1)
- tissue temperature (1)
- titanium dioxide photoanode (1)
- transmit antenna arrays (1)
- transponder (1)
- transporters (1)
- tri-lineage differentiation (1)
- truss (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- ultrathin gate insulators (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- urease (1)
- validation methods (1)
- vault (1)
- vessels (1)
- video learning (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual clean room (1)
- viscoelasticity (1)
- visualization (1)
- volume flexibility (1)
- walking (1)
- walking gait (1)
- wastewater (1)
- water economy (1)
- water supply design (1)
- wind turbine production (1)
- wound healing (1)
- yield (1)
- yield stress (1)
- α-aminoacylase (1)
- ε-lysine acylase (1)
We introduce a new way to measure the forecast effort that analysts devote to their earnings forecasts by measuring the analyst's general effort for all covered firms. While the commonly applied effort measure is based on analyst behaviour for one firm, our measure considers analyst behaviour for all covered firms. Our general effort measure captures additional information about analyst effort and thus can identify accurate forecasts. We emphasise the importance of investigating analyst behaviour in a larger context and argue that analysts who generally devote substantial forecast effort are also likely to devote substantial effort to a specific firm, even if this effort might not be captured by a firm-specific measure. Empirical results reveal that analysts who devote higher general forecast effort issue more accurate forecasts. Additional investigations show that analysts' career prospects improve with higher general forecast effort. Our measure improves on existing methods as it has higher explanatory power regarding differences in forecast accuracy than the commonly applied effort measure. Additionally, it can address research questions that cannot be examined with a firm-specific measure. It provides a simple but comprehensive way to identify accurate analysts.
Simulation model for the transient process behaviour of solar aluminium recycling in a rotary kiln
(2015)
Capacitive field-effect electrolyte-insulator-semiconductor sensors consisting of an Al-p-Si-SiO2 structure have been used for the electrical detection of unlabelled single- and double-stranded DNA (dsDNA) molecules by their intrinsic charge. A simple functionalization protocol based on the layer-by-layer (LbL) technique was used to prepare a weak polyelectrolyte/probe-DNA bilayer, followed by the hybridization with complementary target DNA molecules. Due to the flat orientation of the LbL-adsorbed DNA molecules, a high sensor signal has been achieved. In addition, direct label-free detection of in-solution hybridized dsDNA molecules has been studied.
Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.
A concept for a new generation of an integrated multi-functional biosensor/actuator system is developed, which is based on biomolecular logic principles. Such a system is expected to be able to detect multiple biochemical input signals simultaneously and in real-time and convert them into electrical output signals with logical operations such as OR, AND, etc. The system can be designed as a closed-loop drug release device triggered by an enzyme logic gate, while the release of the drug induced by the actuator at the required dosage and timing will be controlled by an additional drug sensor. Thus, the system could help to make an accurate and specific diagnosis. The presented concept is exemplarily demonstrated by using an enzyme logic gate based on a glucose/glucose oxidase system, a temperature-responsive hydrogel mimicking the actuator function and an insulin (drug) sensor. In this work, the results of functional testing of individual amperometric glucose and insulin sensors as well as an impedimetric sensor for the detection of the hydrogel swelling/shrinking are presented.
The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).
A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system.
Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen
(2015)
Miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge favor the semiconductor field-effect platform as one of the most attractive approaches for the development of label-free DNA chips. In this work, a capacitive field-effect EIS (electrolyte–insulator–semiconductor) sensor covered with a layer-by-layer prepared, positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was used for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization. The negatively charged probe single-stranded DNA (ssDNA) molecules were electrostatically adsorbed onto the positively charged PAH layer, resulting in a preferentially flat orientation of the ssDNA molecules within the Debye length, thus yielding a reduced charge-screening effect and a higher sensor signal. Each sensor-surface modification step (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), reducing an unspecific adsorption by a blocking agent, incubation with noncomplementary DNA (ncDNA) solution) was monitored by means of capacitance–voltage and constant-capacitance measurements. In addition, the surface morphology of the PAH layer was studied by atomic force microscopy and contact-angle measurements. High hybridization signals of 34 and 43 mV were recorded in low-ionic strength solutions of 10 and 1 mM, respectively. In contrast, a small signal of 4 mV was recorded in the case of unspecific adsorption of fully mismatched ncDNA. The density of probe ssDNA and dsDNA molecules as well as the hybridization efficiency was estimated using the experimentally measured DNA immobilization and hybridization signals and a simplified double-layer capacitor model. The results of field-effect experiments were supported by fluorescence measurements, verifying the DNA-immobilization and hybridization event.
A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent–voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout.
For several thousand years, biotechnology and its associated technical processes have had a great impact on the development of mankind. Based on empirical methods, in particular for the production of foodstuffs and daily commodities, these disciplines have become one of the most innovative future issues. Due to the increasing detailed understanding of cellular processes, production strains can now be optimized. In combination with modern bioprocesses, a variety of bulk and fine chemicals as well as pharmaceuticals can be produced efficiently. In this article, some of the current trends in biotechnology are discussed.
Cytochrome b5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo s
(2015)
An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.
Designing novel or optimizing existing biodegradable polymers for biomedical applications requires numerous tests on the effect of substances on the degradation process. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the first time. The thin films of biodegradable polymer poly(d,l-lactic acid) and enzyme lipase were used as a model system. During degradation, the sensors were read-out by means of impedance spectroscopy. In order to interpret the data obtained from impedance measurements, an electrical equivalent circuit model was developed. In addition, morphological investigations of the polymer surface have been performed by means of in situ atomic force microscopy. The sensor signal change, which reflects the progress of degradation, indicates an accelerated degradation in the presence of the enzyme compared to hydrolysis in neutral pH buffer media. The degradation rate increases with increasing enzyme concentration. The obtained results demonstrate the potential of PMEIS sensors as a very promising tool for in situ and real-time monitoring of degradation of polymers.
High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.
Data-driven prediction and prevention of extreme events in a spatially extended excitable system
(2015)
Due to their anion exchange characteristics, layered double hydroxides (LDHs) are suitable for the detoxification of aqueous, fatty acid containing fermentation substrates. The aim of this study is to examine the adsorption mechanism, using crude glycerol from plant oil esterification as a model system. Changes in the intercalation structure in relation to the amount of fatty acids adsorbed are monitored by X-ray diffraction and infra-red spectroscopy. Additionally, calcination of LDH is investigated in order to increase the binding capacity for fatty acids. Our data propose that, at ambient temperature, fatty acids can be bound to the hydrotalcite by adsorption or in addition by intercalation, depending on fatty acid concentration. The adsorption of fatty acids from crude glycerol shows a BET-like behavior. Above a fatty acid concentration of 3.5 g L−1, intercalation of fatty acids can be shown by the appearance of an increased interlayer spacing. This observation suggests a two phase adsorption process. Calcination of LDHs allows increasing the binding capacity for fatty acids by more than six times, mainly by reduction of structural CO32−.
Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms
(2015)
Let X₁,…,Xₙ be independent and identically distributed random variables with distribution F. Assuming that there are measurable functions f:R²→R and g:R²→R characterizing a family F of distributions on the Borel sets of R in the way that the random variables f(X₁,X₂),g(X₁,X₂) are independent, if and only if F∈F, we propose to treat the testing problem H:F∈F,K:F∉F by applying a consistent nonparametric independence test to the bivariate sample variables (f(Xᵢ,Xⱼ),g(Xᵢ,Xⱼ)),1⩽i,j⩽n,i≠j. A parametric bootstrap procedure needed to get critical values is shown to work. The consistency of the test is discussed. The power performance of the procedure is compared with that of the classical tests of Kolmogorov–Smirnov and Cramér–von Mises in the special cases where F is the family of gamma distributions or the family of inverse Gaussian distributions.
Optimization of the immobilization of bacterial spores on glass substrates with organosilanes
(2016)
Spores can be immobilized on biosensors to function as sensitive recognition elements. However, the immobilization can affect the sensitivity and reproducibility of the sensor signal. In this work, three different immobilization strategies with organosilanes were optimized and characterized to immobilize Bacillus atrophaeus spores on glass substrates. Five different silanization parameters were investigated: nature of the solvent, concentration of the silane, silanization time, curing process, and silanization temperature. The resulting silane layers were resistant to a buffer solution (e.g., Ringer solution) with a polysorbate (e.g., Tween®80) and sonication.
Bonding of polymer-based microfluidics to polymer substrates still poses a challenge for Lab-On-a-Chip applications. Especially, when sensing elements are incorporated, patterned deposition of adhesives with curing at ambient conditions is required. Here, we demonstrate a fabrication method for fully printed microfluidic systems with sensing elements using inkjet and stereolithographic 3D-printing.
A comparative performance analysis of the CFD platforms OpenFOAM and FLOW-3D is presented, focusing on a 3D swirling turbulent flow: a steady hydraulic jump at low Reynolds number. Turbulence is treated using RANS approach RNG k-ε. A Volume Of Fluid (VOF) method is used to track the air–water interface, consequently aeration is modeled using an Eulerian–Eulerian approach. Structured meshes of cubic elements are used to discretize the channel geometry. The numerical model accuracy is assessed comparing representative hydraulic jump variables (sequent depth ratio, roller length, mean velocity profiles, velocity decay or free surface profile) to experimental data. The model results are also compared to previous studies to broaden the result validation. Both codes reproduced the phenomenon under study concurring with experimental data, although special care must be taken when swirling flows occur. Both models can be used to reproduce the hydraulic performance of energy dissipation structures at low Reynolds numbers.
On-line monitoring of the metabolic activity of microorganisms involved in intermediate stages of biogas production plays an important role to avoid undesirable “down times” during the biogas production. In order to control this process, an on-chip differential measuring system based on the light-addressable potentiometric sensor (LAPS) principle combined with a 3D-printed multi-chamber structure has been realized. As a test microorganism, Escherichia coli K12 (E. coli K12) were used for cell-based measurements. Multi-chamber structures were developed to determine the metabolic activity of E. coli K12 in suspension for a different number of cells, responding to the addition of a constant or variable amount of glucose concentrations, enabling differential and simultaneous measurements.
Abstractauthoren Graphene oxide (GO) nanoparticles were incorporated in temperature-sensitive Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels. The nanoparticles increase the light absorption and convert light energy into heat efficiently. Thus, the hydrogels with GO can be stimulated spatially resolved by illumination as it was demonstrated by IR thermography. The temporal progression of the temperature maximum was detected for different concentrations of GO within the polymer network. Furthermore, the compatibility of PNIPAAm hydrogels with GO and cell cultures was investigated. For this purpose, culture medium was incubated with hydrogels containing GO and the viability and morphology of chinese hamster ovary (CHO) cells was examined after several days of culturing in presence of this medium.
Purpose
Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena.
Methods
Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model.
Results
A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained.
Conclusions
The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis.
Self-aeration is traditionally explained by the water turbulent boundary layer outer edge intersection with the free surface. This paper presents a discussion on the commonly accepted hypothesis behind the computation of the critical point of self-aeration in spillway flows and a new formulation is proposed based on the existence of a developing air flow over the free surface. Upstream of the inception point of self-aeration, some surface roughening has been often reported in previous studies which consequently implies some entrapped air transport and air–water flows coupling. Such air flow is proven in this study by presenting measured air velocities and computing the air boundary layer thickness for a 1V:2H smooth chute flow. Additionally, the growth rate of free surface waves has been analysed by means of Ultrasonic Sensors measurements, obtaining also the entrapped air concentration. High-speed camera imaging has been used for qualitative study of the flow perturbations.
Operational Modal Analysis (OMA) is a promising candidate for flutter testing and Structural Health Monitoring (SHM) of aircraft wings that are passively excited by wind loads. However, no studies have been published where OMA is tested in transonic flows, which is the dominant condition for large civil aircraft and is characterized by complex and unique aerodynamic phenomena. We use data from the HIRENASD large-scale wind tunnel experiment to automatically extract modal parameters from an ambiently excited wing operated in the transonic regime using two OMA methods: Stochastic Subspace Identification (SSI) and Frequency Domain Decomposition (FDD). The system response is evaluated based on accelerometer measurements. The excitation is investigated from surface pressure measurements. The forcing function is shown to be non-white, non-stationary and contaminated by narrow-banded transonic disturbances. All these properties violate fundamental OMA assumptions about the forcing function. Despite this, all physical modes in the investigated frequency range were successfully identified, and in addition transonic pressure waves were identified as physical modes as well. The SSI method showed superior identification capabilities for the investigated case. The investigation shows that complex transonic flows can interfere with OMA. This can make existing approaches for modal tracking unsuitable for their application to aircraft wings operated in the transonic flight regime. Approaches to separate the true physical modes from the transonic disturbances are discussed.
We investigate the suitability of selected measures of complexity based on recurrence quantification analysis and recurrence networks for an identification of pre-seizure states in multi-day, multi-channel, invasive electroencephalographic recordings from five epilepsy patients. We employ several statistical techniques to avoid spurious findings due to various influencing factors and due to multiple comparisons and observe precursory structures in three patients. Our findings indicate a high congruence among measures in identifying seizure precursors and emphasize the current notion of seizure generation in large-scale epileptic networks. A final judgment of the suitability for field studies, however, requires evaluation on a larger database.
Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks.
This summer, RoboCup competitions were held for the 20th time in Leipzig, Germany. It was the second time that RoboCup took place in Germany, 10 years after the 2006 RoboCup in Bremen. In this article, we give an overview on the latest developments of RoboCup and what happened in the different leagues over the last decade. With its 20th edition, RoboCup clearly is a success story and a role model for robotics competitions. From our personal view point, we acknowledge this by giving a retrospection about what makes RoboCup such a success.
Ground or aerial robots equipped with advanced sensing technologies, such as three-dimensional laser scanners and advanced mapping algorithms, are deemed useful as a supporting technology for first responders. A great deal of excellent research in the field exists, but practical applications at real disaster sites are scarce. Many projects concentrate on equipping robots with advanced capabilities, such as autonomous exploration or object manipulation. In spite of this, realistic application areas for such robots are limited to teleoperated reconnaissance or search. In this paper, we investigate how well state-of-the-art and off-the-shelf components and algorithms are suited for reconnaissance in current disaster-relief scenarios. The basic idea is to make use of some of the most common sensors and deploy some widely used algorithms in a disaster situation, and to evaluate how well the components work for these scenarios. We acquired the sensor data from two field experiments, one from a disaster-relief operation in a motorway tunnel, and one from a mapping experiment in a partly closed down motorway tunnel. Based on these data, which we make publicly available, we evaluate state-of-the-art and off-the-shelf mapping approaches. In our analysis, we integrate opinions and replies from first responders as well as from some algorithm developers on the usefulness of the data and the limitations of the deployed approaches, respectively. We discuss the lessons we learned during the two missions. These lessons are interesting for the community working in similar areas of urban search and rescue, particularly reconnaissance and search.
In the field of biotechnology and molecular biology, the use of small liquid volumes has significant advantages. In particular, screening and optimization runs with acceptable amounts of expensive and hardly available catalysts, reagents, or biomolecules are feasible with microfluidic technologies. The presented new microfluidic system is based on the inclusion of small liquid volumes by a protective shell of magnetizable microparticles. Hereby, discrete aqueous microreactor drops with volumes of 1–30 μL can be formed on a simple planar surface. A digital movement and manipulation of the microreactor is performed by overlapping magnetic forces. The magnetic forces are generated by an electrical coil matrix positioned below a glass plate. With the new platform technology, several discrete reaction compartments can be moved simultaneously on one surface. Due to the magnetic fields, the reactors can even be merged to initiate reactions by mixing or positioned above surface-immobilized catalysts and then opened by magnetic force. Comparative synthesis routes of the magnetizable shell particles and superhydrophobic glass slides including their performance and stability with the reaction platform are described. The influence of diffusive mass transport during the catalyzed reaction is discussed by evaluation finite element model of the microreactor. Furthermore, a first model dye reaction of the enzyme laccase has been established.
The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.
Robots are widely used as a vehicle to spark interest in science and technology in learners. A number of initiatives focus on this issue, for instance, the Roberta Initiative, the FIRST Lego League, the World Robot Olympiad and RoboCup Junior. Robotic competitions are valuable not only for school learners but also for university students, as the RoboCup initiative shows. Besides technical skills, the students get some project exposure and experience what it means to finish their tasks on time. But qualifying students for future high-tech areas should not only be for students from developed countries. In this article, we present our experiences with research and education in robotics within the RoboCup initiative, in Germany and South Africa; we report on our experiences with trying to get the RoboCup initiative in South Africa going. RoboCup has a huge support base of academic institutions in Germany; this is not the case in South Africa. We present our ‘north–south’ collaboration initiatives in RoboCup between Germany and South Africa and discuss some of the reasons why we think it is harder to run RoboCup in South Africa.