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Zugriffsart
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Numerik-Algorithmen : Verfahren, Beispiele, Anwendungen. - 9., vollst. überarb. und erw. Aufl.
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The carbonized rice husk (CRH) was evaluated for its wound healing activity in rats using excision models. In this study, the influences of CRH on wound healing in rat skin in vivo and cellular behavior of human dermal fibroblasts in vitro were investigated. The obtained results showed that the CRH treatment promoted wound epithelization in rats and exhibited moderate inhibition of cell proliferation in vitro. CRH with lanolin oil treated wounds were found to epithelize faster as compared to controls.
Recently, the SHARP Corporation, Japan, has developed the world’s first "Plasma Cluster Ions (PCI)" air purification technology using plasma discharge to generate cluster ions. The new plasma cluster device releases positive and negative ions into the air, which are able to decompose and deactivate harmful airborne substances by chemical reactions. Because cluster ions consist of positive and negative ions that normally exist in the natural world, they are completely harmless and safe to humans. The amount of ozone generated by cluster ions is less than 0.01 ppm, which is significantly less than the 0.05-ppm standard for industrial operations and consumer electronics. This amount, thus, has no harming effects whatsoever on the human body. But particular properties and chemical processes in PCI treatment are still under study. It has been shown that PCI in most cases show strongly pronounced irreversible killing effects in respect of airborne microflora due to free-radical induced reactions and can be considered as a potent technology to disinfect both home, medical and industrial appliances.
Summary and Conclusions PCIs were clearly effective in terms of their antibacterial effects with the strains tested. This efficacy increased with the time the bacteries were exposed to PCIs. The bactericidal action has proved to be irreversible. PCIs were significantly less effective in shadowed areas. PCI exposure caused multiple protein damages as observed in SDS PAGE studies. There was no single but multiple molecular mechanism causing the bacterial death.
Recently, SHARP corporation has developed the world’s first “Plasma Cluster Ions (PCI)” air purification technology, which uses plasma discharge to generate cluster ions. The new plasma cluster device releases into the air positive and negative ions, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. A lot of phenomenological tests of the PCI air purification technology on microbial cells have been conducted. And, in most cases, it has been shown that PCI demonstrate strongly pronounced killing effect. Although, the particular mechanisms of PCI action are still not evident. We studied variations in resistance to PCI among gram-positive airborne microorganisms, as well as some dose-dependent, spatial, cultural and biochemical properties of PCI action in respect of Staphylococcus spp, Enterococcus spp, Micrococcus spp.
Recently, SHARP corporation has developed the world’s first "Plasma Cluster Ions® (PCI)" air purification technology, which uses plasma discharge to generate cluster ions. The new Plasma Cluster Device releases positive and negative ions into the air, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. In the past, phenomenological tests on the efficacy of the PCI air purification technology on microbial cells have been conducted. In most cases, it has been shown that PCI demonstrated strongly pronounced killing effects on microorganisms. However, the particular mechanisms of PCI action still have to be uncovered.
Mechanical stimulation of the cells resulted in evident changes in the cell morphology, protein composition and gene expression. Microscopically, additional formation of stress fibers accompanied by cell re-arrangements in a monolayer was observed. Also, significant activation of p53 gene was revealed as compared to control. Interestingly, the use of CellTech membrane coating induced cell death after mechanical stress had been applied. Such an effect was not detected when fibronectin had been used as an adhesion substrate.
The sorption of LPS toxic shock by nanoparticles on base of carbonized vegetable raw materials
(2008)
Immobilization of lactobacillus on high temperature carbonizated vegetable raw material (rice husk, grape stones) increases their physiological activity and the quantity of the antibacterial metabolits, that consequently lead to increase of the antagonistic activity of lactobacillus. It is implies that the use of the nanosorbents for the attachment of the probiotical microorganisms are highly perspective for decision the important problems, such as the probiotical preparations delivery to the right address and their attachment to intestines mucosa with the following detoxication of gastro-intestinal tract and the normalization of it’s microecology. Besides that, thus, the received carbonizated nanoparticles have peculiar properties – ability to sorption of LPS toxical shock and, hence, to the detoxication of LPS.
A melting probe equipped with autofluorescence-based detection system combined with a light scattering unit, and, optionally, with a microarray chip would be ideally suited to probe icy environments like Europa’s ice layer as well as the polar ice layers of Earth and Mars for recent and extinct live.
As a deduction from these results, we can conclude that proteins mainly in vitro, denaturate totally at a temperature between 57°C -62°C, and they also affected by NO and different ions types. In which mainly, NO cause earlier protein denaturation, which means that, NO has a destabilizing effect on proteins, and also different ions will alter the protein denaturation in which, some ions will cause earlier protein denaturation while others not.
The absence of a general method for endotoxin removal from liquid interfaces gives an opportunity to find new methods and materials to overcome this gap. Activated nanostructured carbon is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study is to find the adsorption rates for a carboneous material produced at different temperatures, as well as to reveal possible differences between the performance of the material for each of the adsorbates used during the study (hemoglobin, serum albumin and lipopolysaccharide, LPS).
One of interesting but not well known water properties is related to appearance of highly ordered structures in response to strong electrical field. In 1893 Sir William Armstrong placed a cotton thread between two wine glasses filled with chemically pure water. When high DC voltage was applied between the glasses, a connection consisting of water formed, producing a "water bridge"
We present the novel concept of a combined drilling and melting probe for subsurface ice research. This probe, named “IceMole”, is currently developed, built, and tested at the FH Aachen University of Applied Sciences’ Astronautical Laboratory. Here, we describe its first prototype design and report the results of its field tests on the Swiss Morteratsch glacier. Although the IceMole design is currently adapted to terrestrial glaciers and ice shields, it may later be modified for the subsurface in-situ investigation of extraterrestrial ice, e.g., on Mars, Europa, and Enceladus. If life exists on those bodies, it may be present in the ice (as life can also be found in the deep ice of Earth).
Tests with palm tree leaves have just started yet and scan data are in the process to be analyzed. The final goal of future project for palm tree gender and species recognition will be to develop optical scanning technology to be applied to date palm tree leaves for in–situ screening purposes. Depending on the software used and the particular requirements of the users the technology potentially shall be able to identify palm tree diseases, palm tree gender, and species of young date palm trees by scanning leaves.
The ”IceMole“ is a novel maneuverable subsurface ice probe for clean in-situ analysis and sampling of subsurface ice and subglacial water/brine. It is developed and build at FH Aachen University of Applied Sciences’ Astronautical Laboratory. A first prototype was successfully tested on the Swiss Morteratsch glacier in 2010. Clean sampling is achieved with a hollow ice screw (as it is used in mountaineering) at the tip of the probe. Maneuverability is achieved with a differentially heated melting head. Funded by the German Space Agency (DLR), a consortium led by FH Aachen currently develops a much more advanced IceMole probe, which includes a sophisticated system for obstacle avoidance, target detection, and navigation in the ice. We intend to use this probe for taking clean samples of subglacial brine at the Blood Falls (McMurdo Dry Valleys, East Antarctica) for chemical and microbiological analysis. In our conference contribution, we 1) describe the IceMole design, 2) report the results of the field tests of the first prototype on the Morteratsch glacier, 3) discuss the probe’s potential for the clean in-situ analysis and sampling of subsurface ice and subglacial liquids, and 4) outline the way ahead in the development of this technology.
The most of conventional methods of air purification use the power of a fan to draw in air and pass it through a filter. The problem of bacterial contamination of inner parts of such a type of air conditioners in some cases draws attention towards alternative air-cleaning systems. Some manufacturers offer to use the ozone's bactericidal and deodorizing effects, but the wide spreading of such systems is restricted by the fact that toxic effects of ozone in respect of human beings are well known. In 2000 Sharp Inc. introduced "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions (I 0-14 ). This technology has been developed for those customers that are conscious about health and hygiene. In our experiments, we focused on some principal aspects of plasma-generated ions application - time-dependency and irreversibility of bactericidal action, spatial and kinetic characteristics of emitted cluster particles, their chemical targets in the microbial cells.
FH Aachen Dimensionen 01/12 Herausgeber : Rektor der FH Aachen Inhaltsverzeichnis Thema 06 Vielfalt integrieren - nachhaltig fördern | Mit einer systematischen Qualitätsentwicklung von Studium und Lehre reagiert die FH Aachen auf den Studienandrang 12 "Wir sprechen niemandem die Studierfähigkeit ab" | Prof. Helmut Jakobs und Dr. Michael Heger äußern sich zur Bildungspolitik und den Herausforderungen der Hochschule in den kommenden Jahren Studium 14 Extraraum für Aachen | NRW-Wissenschaftsministerin Svenja Schulze auf „Hochschul-Tour zum doppelten Abiturjahrgang“ 18 Wohnen auf Zeit | Studierende des Fachbereichs Architektur entwickeln temporäre Wohnformen für die Zeit des Studierendenandrangs 19 Spioniert mein Handy mich aus? | FH-Student Michael Stahl hat eine App geschrieben, die die Internet-Kommunikation seines Smartphones mitschneidet und auswertet 20 Hoch hinaus | FH Aachen entwickelt zusammen mit der Polytechnik- Universität ersten Architekturstudiengang in Namibia 22 Wenn ein Rad ins andere greift | FH Aachen bietet neuen Masterstudiengang „Automatisierungs- und Antriebstechnik“ erstmals im Sommersemester 2012 an 23 Stabiler Lichtbogen | Andreas Bügener testete für eine belgische Firma neuartige Schweißverfahren 24 Student Sven von Osten gewinnt Corporate-Design-Wettbewerb | „Elektromobilität Region Aachen“ hat ein neues Markenzeichen 26 Doppelt gemoppelt hält besser | Studiengang Bauingenieurwesen - Netzingenieur öffnet sich für Handwerksberufe 27 Meldungen / Studium International 28 Erstes Parabolrinnen-Kraftwerk in Thailand | FH-Absolventen waren am Bau der Anlage beteiligt 32 Zirvedekiler | Zwei FH-Professoren befinden sich „in bester Gesellschaft“ 34 Der High-Level-Master für Wirtschaftswissenschaftler | Der OpenBordersMBA punktet mit seiner Internationalität 36 Meldungen / International Forschung 38 Geheimnisvoller Eismond | FH Aachen entwickelt Technik für die Erforschung des Saturnmondes Enceladus 42 Wie ein Blitz | FH-Forscher entwickeln 3400 Grad heißen Plasma-Laser 44 Gegen den Durst | FH entwickelt für Namibia ein mehrstufiges System zur solarthermischen Grundwasseraufbereitung 46 Nachwuchs forscht | FH-Doktoranden präsentieren und diskutieren die Ergebnisse ihrer wissenschaftlichen Arbeit 48 „Global denken – lokal handeln“ | NOWUM-Energy gestaltet lokales Klimaschutzkonzept für Gangelt 49 Meldungen / Forschung Personen 50 „Plötzlich waren vier Kalaschnikows auf mich gerichtet“ | FH-Student Fabian Nawrath war sieben Monate mit dem Fahrrad in Afrika unterwegs 54 Der Ausdauernde | Kanzler Rainer Smeetz geht nach 38 Jahren in Ruhestand 55 Zum 100. Geburtstag von Wernher von Braun | FH veröffentlicht Sonderpublikation mit einem Essay von Prof. Dr. Jesco Freiherr von Puttkamer 56 Der Ingenieur der Phantasia-Welten | FH-Absolvent Ralf-Richard Kenter ist heute Chef des berühmtesten Freizeitparks Deutschlands 58 Verdienter Lohn | 56 Studierende erhalten ein Jahr lang ein Stipendium 60 Ehrenplakettenträger und Absolventen 2011 74 Personalia 76 Buchtipps 77 Neuberufene Professorinnen und Professoren 79 Ausscheidende Professoren 80 Nachwort | Aachener Flugpionier Richard Perlia mit 106 Jahren verstorben Service 82 „Helle Köpfe“ erforschen die Haut des Wassers | Prof. Dr. Günter Jakob Lauth erklärt Viertklässlern, was hinter der Oberflächenspannung steckt 84 Mobile Behörde | Ausländeramt des Kreises Düren bietet neuen Service am Campus Jülich 86 Über die Zukunft der Fachhochschulen | Gemeinsame Veranstaltung von GEW und FH Aachen 87 „Eine faire und transparente Lösung“ | Durch die Einführung flexibler Arbeitszeiten starten Mitarbeiterinnen und Mitarbeiter entspannt in den Arbeitstag 88 Meldungen / Service 90 Messen und Veranstaltungen 94 Ortswechsel / Dreiländereck 95 Impressum
Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.
The demand of replacements for inoperable organs exceeds the amount of available organ transplants. Therefore, tissue engineering developed as a multidisciplinary field of research for autologous in-vitro organs. Such three dimensional tissue constructs request the application of a bioreactor. The UREPLACE bioreactor is used to grow cells on tubular collagen scaffolds OPTIMAIX Sponge 1 with a maximal length of 7 cm, in order to culture in vitro an adequate ureter replacement. With a rotating unit, (urothelial) cells can be placed homogeneously on the inner scaffold surface. Furthermore, a stimulation is combined with this bioreactor resulting in an orientation of muscle cells. These culturing methods request a precise control of several parameters and actuators. A combination of a LabBox and the suitable software LabVision is used to set and conduct parameters like rotation angles, velocities, pressures and other important cell culture values. The bioreactor was tested waterproof successfully. Furthermore, the temperature controlling was adjusted to 37 °C and the CO2 - concentration regulated to 5 %. Additionally, the pH step responses of several substances showed a perfect functioning of the designed flow chamber. All used software was tested and remained stable for several days.
Plant physiology and plant stress: Plant physiology will be much more important for human mankind because of yield and cultivation limits of crops determined by their resistance to stress. To assess and counteract various stress factors it is necessary to conduct plant research to gain information and results on plant physiology.
The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing.
Mit freundlicher Genehmigung der Autoren und des Oldenbourg Industrieverlags https://www.oldenbourg-industrieverlag.de/de/9783835633223-33223 erschienen als Beitrag im Tagungsband zur AALE-Tagung 2012. 9. Fachkonferenz 4.-5. Mai 2012, Aachen, Fachhochschule. ISBN 9783835633223 S 5-1 S. 127-135 Es werden Ergebnisse unterschiedlicher Projekte aus dem Bereich der Simulation von Wärmeübertragungsprozessen mit Excel-VBA vorgestellt. - Thermische Behandlung hochviskoser Fruchtzubereitungen, verschiedene Projekte und Kooperationen mit der Zentis GmbH & Co. KG, Aachen (J. Becker, U. Feuerriegel, G. Wersch). - Untersuchung des dynamischen Verhaltens von dampfbeheizten Ethylen-Verdampfern. Projekt mit der TGE Gas Engineering GmbH, Bonn (M. Ecker, U. Feuerriegel, U. Hoffmann, S. Wittenhorst). - Dynamische Simulation des axialen Temperaturverlaufs von elektrisch beheizten Rohrreaktoren. Kooperation mit dem Institut für Chemische Verfahrenstechnik, TU Clausthal (U. Feuerriegel, U. Kunz, M. Pook, S. Wittenhorst).
Pandaboard, TurtleBot, Kinect und Co. : Low-Cost Hardware im Lehreinsatz für die mobile Robotik.
(2012)
Mit freundlicher Genehmigung der Autoren und des Oldenbourg Industrieverlags https://www.oldenbourg-industrieverlag.de/de/9783835633223-33223 erschienen als Beitrag im Tagungsband zur AALE-Tagung 2012. 9. Fachkonferenz 4.-5. Mai 2012, Aachen, Fachhochschule. ISBN 9783835633223 S 8-1 S. 229-238 Original-Abstract des Autors: "Die mobile Robotik wird durch den Einsatz von Low-Cost Hardware einem breiten Publikum zugänglich. Bis vor kurzem basierte eine erschwingliche Hardware meist auf Mikrocontrollern mit den entsprechenden Leistungseinschränkungen z.B. im Bereich der Bildverarbeitung. Die Wahrnehmung einer 3D-Umgebung und somit die Möglichkeit zur autonomen Navigation wurde mit relativ kostenintensiver Hardware, z.B. Stereo-Vision-Systemen und Laserscannern gelöst. Die zur Auswertung der Sensorik notwendige Rechenleistung stand - entweder aufgrund des Stromverbrauchs oder der Performance meist für mobile Plattformen (lokal) - nicht zur Verfügung. Durch Einsatz von leistungsfähigen Prozessoren aus dem Bereich der Mobilgeräte (Smartphones, Tablets) und neuartigen Sensoren des Consumer-Bereichs, wie der Kinect, können mobile Roboter kostengünstig für den Einsatz in der Lehre aufgebaut werden.
Mit freundlicher Genehmigung der Autoren und des Oldenbourg Industrieverlags https://www.oldenbourg-industrieverlag.de/de/9783835633223-33223 erschienen als Beitrag im Tagungsband zur AALE-Tagung 2012. 9. Fachkonferenz 4.-5. Mai 2012, Aachen, Fachhochschule. ISBN 9783835633223 S 6-2. S. 165-174 Zusammenfassung der Autoren: "Abschließend kann festgehalten werden, dass die gesamten durchgeführten Überlegungen von den Messergebnissen der Inbetriebnahme positiv bestätigt werden. Es wird durch diese Topologie eine maximale Systemverfügbarkeit garantiert und die Zellen werden optimal betrieben. Ein Blick in die Zukunft für dieses Projekt zeigt viele Erweiterungs- und Optimierungsaufgaben. So muss der DC/DC-Wandler für einen bidirektionalen Betrieb erweitert werden, um einen Rekuperationsbetrieb zu gewährleisten bzw. die Zellen laden zu können. Dadurch können gleichzeitig die Gleichrichterdioden im Sekundärleistungsteil durch IGBTs oder MOSFETs ersetzt werden. Die voll funktionsfähige Version des DC/DC-Wandlers könnte höchstwahrscheinlich direkt auf die Anschlusspole der Zelle montiert werden, wodurch das Gewicht gesenkt wird. Durch die verringerte Verlustleistung in den Zuleitungen könnte der Wirkungsgrad noch einmal gesteigert werden.