Real-time detection of CO by eukaryotic cells
- In this contribution, we focus on the detection of toxic gases with living eukaryotic cells. A cell-based gas sensor system, able to measure the effects of direct exposure of gases to cells in real-time, was set up. Impedance data as well as oxygen consumption of Chinese hamster lung fibroblast cells (V79) were analysed upon exposure to carbon monoxide (CO). The CO (diluted in wet synthetic air) affects the cell respiration as indicated by an attenuated respiration signal after the CO exposure as well as an instant increase of the capacitive part of the impedance signal during the gas exposure.
| Author: | Ulrich Bohrn, Evamaria Stütz, Maximilian Fleischer, Michael Josef SchöningORCiD |
|---|---|
| ISSN: | 1877-7058 |
| Parent Title (English): | Procedia Engineering |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2010 |
| Date of the Publication (Server): | 2012/12/18 |
| Volume: | 5 |
| First Page: | 17 |
| Last Page: | 20 |
| Note: | Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria |
| Link: | https://doi.org/10.1016/j.proeng.2010.09.037 |
| Zugriffsart: | campus |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
