Refine
Year of publication
Document Type
- Article (402)
- Conference Proceeding (145)
- Part of a Book (34)
- Book (7)
- Doctoral Thesis (3)
- Other (3)
- Lecture (2)
- Patent (1)
- Talk (1)
Language
- English (598) (remove)
Keywords
- Finite-Elemente-Methode (7)
- Limit analysis (6)
- Clusterion (5)
- Shakedown analysis (5)
- solar sail (5)
- Air purification (4)
- Einspielen <Werkstoff> (4)
- Hämoglobin (4)
- Lipopolysaccharide (4)
- Luftreiniger (4)
- Plasmacluster ion technology (4)
- Raumluft (4)
- Sonde (4)
- CellDrum (3)
- Eisschicht (3)
- GOSSAMER-1 (3)
- Kohlenstofffaser (3)
- MASCOT (3)
- lipopolysaccharides (3)
- shakedown analysis (3)
- Analytischer Zulaessigkeitsnachweis (2)
- Biocomposites (2)
- Bruchmechanik (2)
- Einspiel-Analyse (2)
- Erythrozyt (2)
- FEM (2)
- Fibroblast (2)
- Iterative learning control (2)
- Mars (2)
- Natural fibres (2)
- Pflanzenphysiologie (2)
- Pflanzenscanner (2)
- Polymer-matrix composites (2)
- Shakedown (2)
- Solar sail (2)
- Spacecraft (2)
- Stickstoffmonoxid (2)
- Stiffness (2)
- Stress concentrations (2)
- Technische Mechanik (2)
- Trajectory Optimization (2)
- bacterial cellulose (2)
- biopotential electrodes (2)
- carbonized rice husk (2)
- celldrum technology (2)
- damage (2)
- locomotion (2)
- multiple NEA rendezvous (2)
- muscle fascicle behavior (2)
- nanostructured carbonized plant parts (2)
- nanostrukturierte carbonisierte Pflanzenteile (2)
- nitric oxide gas (2)
- plant scanner (2)
- prebiotic (2)
- ratchetting (2)
- shakedown (2)
- small spacecraft (2)
- ultrasound (2)
- ultrasound imaging (2)
- Achilles tendon (1)
- Adaptive control (1)
- Adsorption (1)
- Ageing (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Anastomose (1)
- Anastomosis (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Antarctic Glaciology (1)
- Antarctica (1)
- Architectural gear ratio (1)
- Assistive technology (1)
- Asteroid Deflection (1)
- Attitude dynamics (1)
- Autofluoreszenzverfahren (1)
- Autolysis (1)
- Automated Optimization (1)
- Automatic control (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Bakterien (1)
- Biomechanical simulation (1)
- Biomechanics (1)
- Biomechanik (1)
- Biomedizinische Technik (1)
- Bioreaktor (1)
- Biosolubilization (1)
- Bladder (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Bone sawing (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Chance constrained programming (1)
- Circular Dichroism (1)
- Coefficient of ocular rigidity (1)
- Collagen fibrils (1)
- Compression (1)
- Computational biomechanics (1)
- Connective tissues (1)
- Constitutive model (1)
- Contractile tension (1)
- Corneo-scleral shell (1)
- Cost-effectiveness (1)
- Culture media (1)
- DLR-ESTEC GOSSAMER roadmap for solar sailing (1)
- Damage mechanics theory (1)
- Dattel (1)
- Decomposition (1)
- Deformation (1)
- Dekontamination (1)
- Design-by-analysis (1)
- Differential tonometry (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Druckbeanspruchung (1)
- Druckbehälter (1)
- Druckbelastung (1)
- Drug simulation (1)
- Dry surfaces (1)
- EEG (1)
- ES-FEM (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastostatics (1)
- Electromechanical modeling (1)
- Elektrodynamik (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Endothelzelle (1)
- Environmental impact (1)
- Epithel (1)
- Evolution of damage (1)
- Evolutionary Neurocontrol (1)
- Exact Ilyushin yield surface (1)
- Experiment (1)
- Extension fracture (1)
- Extension strain criterion (1)
- External knee adduction moments (1)
- Extracellular matrix (ECM) (1)
- Extraterrestrial Glaciology (1)
- Eyeball (1)
- FGF23 (1)
- FS-FEM (1)
- Fehlerstellen (1)
- Finite element analysis (1)
- Finite element analysis (FEA) (1)
- Finite element method (1)
- Finite element modelling (1)
- First Order Reliabiblity Method (1)
- First-order reliability method (1)
- Fließgrenze (1)
- Force (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Geriatric (1)
- Glaciological instruments and methods (1)
- Glaucoma (1)
- Global and local collapse (1)
- Gossamer (1)
- Gossamer structures (1)
- Grenzwertberechnung (1)
- Growth modelling (1)
- Haemodialysis (1)
- Handbike (1)
- Harnleiter (1)
- Heart tissue culture (1)
- Hemoglobin structure (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Homogenization (1)
- Human-Computer interaction (1)
- Hybrid Propellants (1)
- Hydrodynamik (1)
- Hydrogel (1)
- Hämoglobinstruktur (1)
- Ice melting probe (1)
- Ice penetration (1)
- Icy moons (1)
- Impedance Spectroscopy (1)
- Induced pluripotent stem cells (1)
- Inotropic compounds (1)
- Interplanetary flight (1)
- Interstellar objects (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Ion channels (1)
- Jupiter (1)
- Kinematics (1)
- Kinetics (1)
- Klotho (1)
- Knee (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Körpertemperatur (1)
- LPS (1)
- Lactobacillus rhamnosus GG (1)
- Lichtstreuungsbasierte Instrumente (1)
- Liver (1)
- Load modeling (1)
- Long COVID (1)
- Low-Thrust Propulsion (1)
- Machine learning (1)
- Manipulated variables (1)
- Mechanical simulation (1)
- Mechanical stability (1)
- Mechanics (1)
- Mechanische Beanspruchung (1)
- Mechanotransduction (1)
- Medusomyces gisevi (1)
- Microbial adhesion (1)
- Microcirculation (1)
- Mild cognitive impairment (1)
- Missions (1)
- Mohr–Coulomb criterion (1)
- Multimode failure (1)
- Multiphase (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Muscle fibers (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Natriumhypochlorit (1)
- Niacin (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-linear optimization (1)
- Non-parallel fissures (1)
- Nucleus Pulposus (1)
- Ocean worlds (1)
- Ocular blood flow (1)
- Orbital dynamics (1)
- Organkultur (1)
- Osteoporose (1)
- Osteoporosis (1)
- PFM (1)
- PHILAE (1)
- PTH (1)
- Paralympic sport (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Permeability (1)
- Permeabilität (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Phosphate (1)
- Physiology (1)
- Planetary Protection (1)
- Planetary exploration (1)
- Plastizität (1)
- Post-COVID-19 syndrome (1)
- Pressure loaded crack-face (1)
- Pressure-volume relationship (1)
- Prevention (1)
- Progressive plastic deformation (1)
- Prophylaxis (1)
- Proteine (1)
- Proximal humerus fracture (1)
- Pulsations (1)
- RVA (1)
- Random variable (1)
- Ratcheting (1)
- Ratchetting (1)
- Recombinant activated protein C (1)
- Reconstruction (1)
- Red blood cell storage (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Reliability analysis (1)
- Reliability of structures (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Reusable Rocket Engines (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Rohr (1)
- Rohrbruch (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- Sampling methods (1)
- Schwammknochen (1)
- Sensitivity (1)
- Sepsis (1)
- Septic cardiomyopathy (1)
- Sequence-Search (1)
- Shakedown criterion (1)
- Simulation (1)
- Skeletal muscle (1)
- Sleep EEG (1)
- Small Aral Sea (1)
- Small Solar System Body Lander (1)
- Small Spacecraft (1)
- Small spacecraft (1)
- Solar Power Sail (1)
- Solar Sail (1)
- Spacecraft Trajectory Optimization (1)
- Spleen (1)
- Stahl (1)
- Statics (1)
- Stochastic programming (1)
- Strukturanalyse (1)
- Subclacial exploration (1)
- Subglacial lakes (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Swabbing (1)
- Tapered ends (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Thiamine (1)
- Tissue Engineering (1)
- Traglastanalyse (1)
- Training (1)
- Trajectories (1)
- Ultrasound (1)
- Uniaxial compression test (1)
- Ureter (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- Wasserbrücke (1)
- Wasserstoffperoxid (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Wundheilung (1)
- Zug-Druck Belastung (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- activated nanostructured carbon (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- aktivierte nanostrukturierte Kohlenstofffaser (1)
- alternierend Verformbarkeit (1)
- anaesthetic complications (1)
- anisotropy (1)
- aortic perfusion (1)
- asteroid lander (1)
- asteroid sample return (1)
- attitude dynamics (1)
- autofluorescence-based detection system (1)
- biaxial tensile experiment (1)
- biofilms (1)
- biomechanics (1)
- bone density (1)
- bone structure (1)
- burst pressure (1)
- burst tests (1)
- cancellous bone (1)
- cardiomyocyte biomechanics (1)
- cell aerosolization (1)
- cell atomization (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- coculture (1)
- cognitive impairment (1)
- community dwelling (1)
- computational fluid dynamics analysis (1)
- connective tissue (1)
- constitutive modeling (1)
- constructive alignment (1)
- contractile tension (1)
- correlation (1)
- crop yield (1)
- cytosolic water diffusion (1)
- date palm tree (1)
- dental trauma (1)
- design-by-analysis (1)
- dialysis (1)
- difficult airway (1)
- distorted element (1)
- double-lumen tube intubation (1)
- drop jump (1)
- ecological structure (1)
- electromyography (1)
- endoluminal (1)
- energy absorption (1)
- energy dissipation (1)
- epithelization (1)
- examination (1)
- exopolysaccharides (1)
- extracorporeal membrane oxygenation (1)
- finite element analysis (1)
- flaw (1)
- flotilla missions (1)
- force generation (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- gait (1)
- habitability (1)
- healthy aging (1)
- heliosphere (1)
- hemoglobin (1)
- hemoglobin dynamics (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- human dermal fibroblasts (1)
- humic acid (1)
- hydrogel (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- ice moons (1)
- icy moons (1)
- immobilization (1)
- impedance spectroscopy (1)
- in-ear EEG (1)
- intraclass correlation coefficient (1)
- ion propulsion (1)
- kontraktile Spannung (1)
- life detection (1)
- light scattering analysis (1)
- lignite (1)
- limit analysis (1)
- limit and shakedown analysis (1)
- linear kinematic hardening (1)
- lipopolysaccharide (1)
- load limit (1)
- long-term retention (1)
- low-rank coal (1)
- low-thrust (1)
- low-thrust trajectory optimization (1)
- material shakedown (1)
- mechanical buffer (1)
- metagenomics (1)
- microbial diversity (1)
- multimodal (1)
- muscle mechanics (1)
- near-Earth asteroid (1)
- non-simplex S-FEM elements (1)
- nonlinear kinematic hardening (1)
- orbit control (1)
- orbital dynamics (1)
- overload (1)
- parabolic flight (1)
- performance testing (1)
- physiology (1)
- pipes (1)
- planetary defence (1)
- plant stress (1)
- plasma generated ions (1)
- practical learning (1)
- prevention (1)
- probabilistic fracture mechanics (1)
- protein (1)
- psychosocial (1)
- pullulan (1)
- rehabilitation (1)
- reliability of structures (1)
- responsive space (1)
- retinal microvasculature (1)
- retinal vessels (1)
- rhAPC (1)
- running (1)
- sEMG (1)
- sailcraft (1)
- sample return (1)
- sarcomere operating length (1)
- second-order reliability method (1)
- sensors (1)
- series elastic element behavior (1)
- shotgun sequencing (1)
- shoulder (1)
- simulation (1)
- small solar system body characterisation (1)
- small spacecraft asteroid lander (1)
- small spacecraft solar sail (1)
- smooth muscle contraction (1)
- soil amendment (1)
- soil health (1)
- soil remediation (1)
- solar sails (1)
- solar system (1)
- space missions (1)
- sprint start (1)
- standard error of measurement (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- subglacial aquatic ecosystems (1)
- subsurface ice (1)
- subsurface ice research (1)
- subsurface probe (1)
- surface modification (1)
- survival (1)
- system engineering (1)
- tendon rupture (1)
- tension–torsion loading (1)
- test-retest reliability (1)
- training simulator (1)
- tri-lineage differentiation (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- underwater vehicle (1)
- unloading (1)
- vessels (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual reality (1)
- viscoelasticity (1)
- walking (1)
- walking gait (1)
- water bridge phenomenon (1)
- wound healing (1)
- yield stress (1)
Institute
- IfB - Institut für Bioengineering (598) (remove)
Recognition of subjects with mild cognitive impairment (MCI) by the use of retinal arterial vessels.
(2019)
Clearance of blood components and fluid drainage play a crucial role in subarachnoid hemorrhage (SAH) and post hemorrhagic hydrocephalus (PHH). With the involvement of interstitial fluid (ISF) and cerebrospinal fluid (CSF), two pathways for the clearance of fluid and solutes in the brain are proposed. Starting at the level of capillaries, flow of ISF follows along the basement membranes in the walls of cerebral arteries out of the parenchyma to drain into the lymphatics and CSF [1]–[3]. Conversely, it is shown that CSF enters the parenchyma between glial and pial basement membranes of penetrating arteries [4]–[6]. Nevertheless, the involved structures and the contribution of either flow pathway to fluid balance between the subarachnoid space and interstitial space remains controversial. Low frequency oscillations in vascular tone are referred to as vasomotion and corresponding vasomotion waves are modeled as the driving force for flow of ISF out of the parenchyma [7]. Retinal vessel analysis (RVA) allows non-invasive measurement of retinal vessel vasomotion with respect to diameter changes [8]. Thus, the aim of the study is to investigate vasomotion in RVA signals of SAH and PHH patients.
Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20–30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P < 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R² = 0.267, β = −0.097 (95% CI = −0.165; −0.029), P = 0.005], but other retinal microvascular parameters were not associated with masked hypertension. In multivariable logistic regression analyses, masked hypertension [OR = 2.333, (95% CI = 1.316; 4.241), P = 0.004] was associated with a narrower CRAE. In young healthy adults, masked hypertension was associated with retinal arteriolar narrowing, thereby reflecting early microvascular alterations known to predict cardiovascular outcomes in later life.
The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.
Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.
Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.
Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.