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- Einspielen <Werkstoff> (7)
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Shakedown analysis of two dimensional structures by an edge-based smoothed finite element method
(2010)
Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection
(2010)
Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs
(2010)
Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 Å at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits.
Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors
(2009)
Microfabrication, characterization and analytical application of a new thin-film silver microsensor
(2009)
Sensing charged macromolecules with nanocrystalline diamond-based field-effect capacitive sensors
(2008)
Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems
(2008)
High resolution and better quantification by tube of responsemodelling in 3D PET reconstruction
(1996)
Flow visualization by means of PIV of an artificial aortic heart valve fixed into a mock aorta
(2005)
Load bearing capacity of thin shell structures made of elastoplastic material by direct methods
(2008)
HisT/PLIER : A Two-Fold Provenance Approach for Grid-Enabled Scientific Workflows Using WS-VLAM
(2011)
468 Scatter dose determination at the eye lens during a mask based whole brain radiotherapy (WBRT)
(2005)