Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (1546)
- Fachbereich Wirtschaftswissenschaften (700)
- Fachbereich Elektrotechnik und Informationstechnik (629)
- Fachbereich Energietechnik (598)
- Fachbereich Chemie und Biotechnologie (589)
- INB - Institut für Nano- und Biotechnologien (523)
- Fachbereich Maschinenbau und Mechatronik (472)
- IfB - Institut für Bioengineering (428)
- Fachbereich Luft- und Raumfahrttechnik (368)
- Fachbereich Bauingenieurwesen (327)
Has Fulltext
- no (5531) (remove)
Language
Document Type
- Article (5531) (remove)
Keywords
- avalanche (5)
- Earthquake (4)
- LAPS (4)
- field-effect sensor (4)
- frequency mixing magnetic detection (4)
- CellDrum (3)
- Heparin (3)
- SLM (3)
- additive manufacturing (3)
- capacitive field-effect sensor (3)
Rechtsfolgen vorbehaltloser Mietzahlung in Mangelkenntnis –Mehr als bloß eine Etappe beim BGH?
(2003)
Rechnerunterstuetzte Aufbereitung von Finite-Elemente-Rechenmodellen-Erfassung der Bauteilgeometrie
(1977)
Rechnerunterstuetzte Aufbereitung von Finite-Elemente-Rechenmodellen -Erstellen der FEM-Netzwerke
(1977)
Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor’s recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential.
The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed.