Refine
Year of publication
Institute
- IfB - Institut für Bioengineering (22) (remove)
Has Fulltext
- yes (22) (remove)
Document Type
- Article (22) (remove)
Keywords
- Einspielen <Werkstoff> (3)
- Air purification (1)
- Alternating plasticity (1)
- Analysis (1)
- Analytischer Zulaessigkeitsnachweis (1)
- Arthosetherapie (1)
- Aufschlagversuch (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- Bacterial cellulose (1)
- Bioreaktor (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Carbon sources (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Clusterion (1)
- Cost-effectiveness (1)
- Culture media (1)
- Deformation (1)
- Design-by-analysis (1)
- Druckbeanspruchung (1)
- Druckbehälter (1)
- Druckbelastung (1)
- Einspiel-Analyse (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Environmental impact (1)
- Epithel (1)
- Experiment (1)
- FEM (1)
- Fehlerstellen (1)
- Fibroblast (1)
- Finite-Elemente-Methode (1)
- Fließgrenze (1)
- Fußball (1)
- Geriatric (1)
- Global and local collapse (1)
- Gonarthrose (1)
- Grenzwertberechnung (1)
- Harnleiter (1)
- Hemoglobin structure (1)
- Hip fractures (1)
- Hämoglobin (1)
- Hämoglobinstruktur (1)
- Kniegelenkarthrose (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Kohlenstofffaser (1)
- Limit analysis (1)
- Lipopolysaccharide (1)
- Luftreiniger (1)
- MBST (1)
- Medusomyces gisevi (1)
- Organkultur (1)
- Osteoporose (1)
- Osteoporosis (1)
- Permeability (1)
- Permeabilität (1)
- Pflanzenphysiologie (1)
- Pflanzenscanner (1)
- Pflanzenstress (1)
- Plasmacluster ion technology (1)
- Plastizität (1)
- Pressure loaded crack-face (1)
- Prevention (1)
- Progressive plastic deformation (1)
- Prophylaxis (1)
- Ratchetting (1)
- Raumluft (1)
- Red blood cell storage (1)
- Rohr (1)
- Rohrbruch (1)
- Schienbeinschoner (1)
- Schwammknochen (1)
- Shakedown (1)
- Shakedown analysis (1)
- Shakedown criterion (1)
- Skeletal muscle (1)
- Small Aral Sea (1)
- Stahl (1)
- Strukturanalyse (1)
- Temperaturabhängigkeit (1)
- Tendons (1)
- Tissue Engineering (1)
- Traglastanalyse (1)
- Ultrasound (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Wundheilung (1)
- Zug-Druck Belastung (1)
- alternierend Verformbarkeit (1)
- arthrosis therapy (1)
- bone density (1)
- bone structure (1)
- burst pressure (1)
- burst tests (1)
- cancellous bone (1)
- carbonized rice husk (1)
- ecological structure (1)
- epithelization (1)
- flaw (1)
- fortschreitende plastische Deformation (1)
- gonarthrosis (1)
- human dermal fibroblasts (1)
- lipopolysaccharides (1)
- load limit (1)
- metagenomics (1)
- microbial diversity (1)
- nanostructured carbonized plant parts (1)
- nanostrukturierte carbonisierte Pflanzenteile (1)
- pipes (1)
- plant scanner (1)
- plant stress (1)
- ratchetting (1)
- shakedown (1)
- shakedown analysis (1)
- shotgun sequencing (1)
- tension–torsion loading (1)
- vessels (1)
- wound healing (1)
- yield stress (1)
Is part of the Bibliography
- no (22)
Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.
An optimization method is developed to describe the mechanical behaviour of the human cancellous bone. The method is based on a mixture theory. A careful observation of the behaviour of the bone material leads to the hypothesis that the bone density is controlled by the principal stress trajectories (Wolff’s law). The basic idea of the developed method is the coupling of a scalar value via an eigenvalue problem to the principal stress trajectories. On the one hand this theory will permit a prediction of the reaction of the biological bone structure after the implantation of a prosthesis, on the other hand it may be useful in engineering optimization problems. An analytical example shows its efficiency.