Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (2072)
- Fachbereich Elektrotechnik und Informationstechnik (1183)
- Fachbereich Wirtschaftswissenschaften (1158)
- Fachbereich Energietechnik (1115)
- Fachbereich Chemie und Biotechnologie (912)
- Fachbereich Maschinenbau und Mechatronik (867)
- Fachbereich Luft- und Raumfahrttechnik (797)
- Fachbereich Bauingenieurwesen (711)
- IfB - Institut für Bioengineering (688)
- INB - Institut für Nano- und Biotechnologien (615)
Language
- German (5099)
- English (4905)
- Russian (14)
- Portuguese (6)
- Multiple languages (5)
- Spanish (3)
- Dutch (2)
- Italian (1)
Document Type
- Article (5642)
- Conference Proceeding (1639)
- Book (1079)
- Part of a Book (559)
- Bachelor Thesis (312)
- Patent (174)
- Report (101)
- Doctoral Thesis (79)
- Other (76)
- Administrative publication (76)
Keywords
- Amtliche Mitteilung (71)
- Bachelor (33)
- Aachen University of Applied Sciences (31)
- Master (31)
- Prüfungsordnung (31)
- Bauingenieurwesen (30)
- Lesbare Fassung (28)
- Biosensor (25)
- Fachhochschule Aachen (23)
- Illustration (22)
Zugriffsart
- campus (2140)
- weltweit (1858)
- bezahl (764)
- fachbereichsweit (FB4) (30)
The growing body of political texts opens up new opportunities for rich insights into political dynamics and ideologies but also increases the workload for manual analysis. Automated speaker attribution, which detects who said what to whom in a speech event and is closely related to semantic role labeling, is an important processing step for computational text analysis. We study the potential of the large language model family Llama 2 to automate speaker attribution in German parliamentary debates from 2017-2021. We fine-tune Llama 2 with QLoRA, an efficient training strategy, and observe our approach to achieve competitive performance in the GermEval 2023 Shared Task On Speaker Attribution in German News Articles and Parliamentary Debates. Our results shed light on the capabilities of large language models in automating speaker attribution, revealing a promising avenue for computational analysis of political discourse and the development of semantic role labeling systems.
Das Ziel der digitalen Arztpraxis-Management-App „PraXma“ ist es, die Organisation von Arztpraxen, sowie auch das Patient:innen- und Terminmanagement einer Praxis effizienter und reibungsloser zu gestalten. Da 83 Prozent der Patient:innen bei der Digitalisierung des deutschen Gesundheitswesens Nachholbedarf sehen, besteht ein erheblicher Bedarf an Weiterentwicklung in dieser Branche. „PraXma“ gewährleistet Patient:innen mithilfe verschiedener Funktionen einen angenehmeren Arztbesuch. Dazu zählen die patientenorientierte Terminvergabe, der kategorisierte Überblick über Vitalwerte und Pässe und die Einsicht in persönliche Dokumente, wie Befunde, Rezepte und mehr. Auch Ärzt:innen profitieren durch „PraXma“ von einer Automatisierung ihrer alltäglichen Abläufe und minimieren so Überstunden und Stress.
CardboardCastle
(2024)
„CardboardCastle“ ist ein 3D-Animationsfilm. Der Film zeigt die lebendig gewordene Welt zweier Königreiche aus Pappe, die in einem Streit um einen magischen Zauberstab verwickelt sind. Das Projekt beweist, dass es möglich ist, mit der Software „Blender“ einen vollwertigen und hochwertigen 3D-Animationsfilm zu erstellen. Dabei wurden alle Assets bis auf Texturen selbst hergestellt. Die virtuelle Pappe spielt hierbei eine fundamentale Rolle, für diese wurde ein vollkommen neuer Workflow entwickelt, welcher es ermöglicht, realistische Pappe zu visualisieren. „CardboardCastle“ setzt auf eine cinematische Inszenierung von Licht und vereint technisches Wissen mit unterhaltenden Inhalten. Dabei zeigt er die kindliche Vorstellungskraft und lädt die Zuschauer ein, sich an ihre eigenen kindlichen Fantasien zu erinnern.
Weltweit sind 350 Millionen Menschen von Farbenfehlsichtigkeit betroffen, doch nur wenige wissen, dass es eine Lösung für genau dieses Problem gibt. Die ausgearbeitete Werbekampagne und neue Markenkommunikation für EnChroma soll genau diese Menschen ermutigen, sich mit ihrer Krankheit auseinanderzusetzen und das breite Konzept der Lösung zu verstehen. Die speziellen Brillen ermöglichen es den Menschen, Farben im Alltag und Berufsleben in echt wahrzunehmen und diese besser differenzieren zu können. Unsere Welt ist farbcodiert und deshalb ist es besonders wichtig, dass diese Menschen auf das Produkt aufmerksam gemacht werden.
Generating synthetic LiDAR point cloud data for object detection using the Unreal Game Engine
(2024)
Object detection based on artificial intelligence is ubiquitous in today’s computer vision research and application. The training of the neural networks for object detection requires large and high-quality datasets. Besides datasets based on image data, datasets derived from point clouds offer several advantages. However, training datasets are sparse and their generation requires a lot of effort, especially in industrial domains. A solution to this issue offers the generation of synthetic point cloud data. Based on the design science research method, the work at hand proposes an approach and its instantiation for generating synthetic point cloud data based on the Unreal Engine. The point cloud quality is evaluated by comparing the synthetic cloud to a real-world point cloud. Within a practical example the applicability of the Unreal Game engine for synthetic point cloud generation could be successfully demonstrated.
As one class of molecular imprinted polymers (MIPs), surface imprinted polymer (SIP)-based biosensors show great potential in direct whole-bacteria detection. Micro-contact imprinting, that involves stamping the template bacteria immobilized on a substrate into a pre-polymerized polymer matrix, is the most straightforward and prominent method to obtain SIP-based biosensors. However, the major drawbacks of the method arise from the requirement for fresh template bacteria and often non-reproducible bacteria distribution on the stamp substrate. Herein, we developed a positive master stamp containing photolithographic mimics of the template bacteria (E. coli) enabling reproducible fabrication of biomimetic SIP-based biosensors without the need for the “real” bacteria cells. By using atomic force and scanning electron microscopy imaging techniques, respectively, the E. coli-capturing ability of the SIP samples was tested, and compared with non-imprinted polymer (NIP)-based samples and control SIP samples, in which the cavity geometry does not match with E. coli cells. It was revealed that the presence of the biomimetic E. coli imprints with a specifically designed geometry increases the sensor E. coli-capturing ability by an “imprinting factor” of about 3. These findings show the importance of geometry-guided physical recognition in bacterial detection using SIP-based biosensors. In addition, this imprinting strategy was employed to interdigitated electrodes and QCM (quartz crystal microbalance) chips. E. coli detection performance of the sensors was demonstrated with electrochemical impedance spectroscopy (EIS) and QCM measurements with dissipation monitoring technique (QCM-D).
Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan (distributed electric propulsion), leading to highly flexible dynamic systems that can exhibit aeroelastic instabilities. This paper introduces a validated methodology to investigate the aeroelastic instabilities of wing–propeller systems and to understand the dynamic mechanism leading to wing and whirl flutter and transition from one to the other. Factors such as nacelle positions along the wing span and chord and its propulsion system mounting stiffness are considered. Additionally, preliminary design guidelines are proposed for flutter-free wing–propeller systems applicable to novel aircraft designs. The study demonstrates how the critical speed of the wing–propeller systems is influenced by the mounting stiffness and propeller position. Weak mounting stiffnesses result in whirl flutter, while hard mounting stiffnesses lead to wing flutter. For the latter, the position of the propeller along the wing span may change the wing mode shapes and thus the flutter mechanism. Propeller positions closer to the wing tip enhance stability, but pusher configurations are more critical due to the mass distribution behind the elastic axis.
Ingenieurwissenschaften im Fokus: Zugänge zu einem effektiven Forschungsdatenmanagement an HAW
(2024)
Im Rahmen der Love Data Week vom 12. bis 16.02.2024 haben die BMBF-Projekte FDM2_TH_Koeln der TH Köln (FK 16FDFH105) und Persist@HAW der FH Aachen (FK 16FDFH129) am 15.02.2024 gemeinsam eine Online-Veranstaltung mit dem Titel „Ingenieurwissenschaften im Fokus: Zugänge zu einem effektiven Forschungsdatenmanagement an HAW“ angeboten. Diese richtete sich an Forschende aus den Ingenieurwissenschaften, die einen ersten Zugang zum Thema Forschungsdatenmanagement (FDM) suchen und erfahren möchten, welche speziellen Angebote für die Daten aus den Ingenieurwissenschaften existieren.
In der Veranstaltung wurden wesentliche Aspekte des Forschungsdatenmanagements entlang des Datenlebenszyklus beleuchtet. Ziel war es, den Teilnehmenden praxisnahe Einblicke und Hilfestellungen zu einem effektiven Umgang mit Forschungsdaten an Hochschulen für Angewandte Wissenschaften (HAW) zu bieten. Durch Beispiele und konkrete Empfehlungen wurde das Thema zugänglich gemacht.
In this work, the effect of low air relative humidity on the operation of a polymer electrolyte membrane fuel cell is investigated. An innovative method through performing in situ electrochemical impedance spectroscopy is utilised to quantify the effect of inlet air relative humidity at the cathode side on internal ionic resistances and output voltage of the fuel cell. In addition, algorithms are developed to analyse the electrochemical characteristics of the fuel cell. For the specific fuel cell stack used in this study, the membrane resistance drops by over 39 % and the cathode side charge transfer resistance decreases by 23 % after increasing the humidity from 30 % to 85 %, while the results of static operation also show an increase of ∼2.2 % in the voltage output after increasing the relative humidity from 30 % to 85 %. In dynamic operation, visible drying effects occur at < 50 % relative humidity, whereby the increase of the air side stoichiometry increases the drying effects. Furthermore, other parameters, such as hydrogen humidification, internal stack structure, and operating parameters like stoichiometry, pressure, and temperature affect the overall water balance. Therefore, the optimal humidification range must be determined by considering all these parameters to maximise the fuel cell performance and durability. The results of this study are used to develop a health management system to ensure sufficient humidification by continuously monitoring the fuel cell polarisation data and electrochemical impedance spectroscopy indicators.
Unmanned Aerial Vehicles (UAV) constantly gain in versatility. However, more reliable path planning algorithms are required until full autonomous UAV operation is possible. This work investigates the algorithm 3DVFH* and analyses its dependency on its cost function weights in 2400 environments. The analysis shows that the 3DVFH* can find a suitable path in every environment. However, a particular type of environment requires a specific choice of cost function weights. For minimal failure, probability interdependencies between the weights of the cost function have to be considered. This dependency reduces the number of control parameters and simplifies the usage of the 3DVFH*. Weights for costs associated with vertical evasion (pitch cost) and vicinity to obstacles (obstacle cost) have the highest influence on the failure probability of the local path planner. Environments with mainly very tall buildings (like large American city centres) require a preference for horizontal avoidance manoeuvres (achieved with high pitch cost weights). In contrast, environments with medium-to-low buildings (like European city centres) benefit from vertical avoidance manoeuvres (achieved with low pitch cost weights). The cost of the vicinity to obstacles also plays an essential role and must be chosen adequately for the environment. Choosing these two weights ideal is sufficient to reduce the failure probability below 10%.
Many important properties of bacterial cellulose (BC), such as moisture absorption capacity, elasticity and tensile strength, largely depend on its structure. This paper presents a study on the effect of the drying method on BC films produced by Medusomyces gisevii using two different procedures: room temperature drying (RT, (24 ± 2 °C, humidity 65 ± 1%, dried until a constant weight was reached) and freeze-drying (FD, treated at − 75 °C for 48 h). BC was synthesized using one of two different carbon sources—either glucose or sucrose. Structural differences in the obtained BC films were evaluated using atomic force microscopy (AFM), scanning electron microscopy (SEM), and X-ray diffraction. Macroscopically, the RT samples appeared semi-transparent and smooth, whereas the FD group exhibited an opaque white color and sponge-like structure. SEM examination showed denser packing of fibrils in FD samples while RT-samples displayed smaller average fiber diameter, lower surface roughness and less porosity. AFM confirmed the SEM observations and showed that the FD material exhibited a more branched structure and a higher surface roughness. The samples cultivated in a glucose-containing nutrient medium, generally displayed a straight and ordered shape of fibrils compared to the sucrose-derived BC, characterized by a rougher and wavier structure. The BC films dried under different conditions showed distinctly different crystallinity degrees, whereas the carbon source in the culture medium was found to have a relatively small effect on the BC crystallinity.
This article addresses the need for an innovative technique in plasma shaping, utilizing antenna structures, Maxwell’s laws, and boundary conditions within a shielded environment. The motivation lies in exploring a novel approach to efficiently generate high-energy density plasma with potential applications across various fields. Implemented in an E01 circular cavity resonator, the proposed method involves the use of an impedance and field matching device with a coaxial connector and a specially optimized monopole antenna. This setup feeds a low-loss cavity resonator, resulting in a high-energy density air plasma with a surface temperature exceeding 3500 o C, achieved with a minimal power input of 80 W. The argon plasma, resembling the shape of a simple monopole antenna with modeled complex dielectric values, offers a more energy-efficient alternative compared to traditional, power-intensive plasma shaping methods. Simulations using a commercial electromagnetic (EM) solver validate the design’s effectiveness, while experimental validation underscores the method’s feasibility and practical implementation. Analyzing various parameters in an argon atmosphere, including hot S -parameters and plasma beam images, the results demonstrate the successful application of this technique, suggesting its potential in coating, furnace technology, fusion, and spectroscopy applications.
Schalung und Gerüste
(2024)
Systemschalungen und Systemgerüste haben den Baustellenbetrieb in vielen Bereichen sehr vereinfacht. Dennoch sind Kenntnisse in diesen Feldern für eine erfolgreiche und effektive Bauleitung unverzichtbar. In diesem Kapitel werden Hinweise und Empfehlungen für die Bemessung und Einsatz von Schalungen, Trag- und Arbeitsgerüsten für den Baustellenbetrieb gegeben.
Kein Bauvorhaben sollte realisiert werden, ohne dass es auf einer vertraglichen Grundlage zwischen Auftraggeber und Auftragnehmer fußt. Diese vertragliche Grundlage zu kennen ist essenziell, um dementsprechend handeln zu können. Denn nur wer seine eigenen Rechte und auch Pflichten kennt, kann sich auf diese berufen.
Die Arbeitsvorbereitung, als ein wesentliches Aufgabengebiet des Baubetriebswesens, ist von enormer Bedeutung für den Erfolg eines Bauprojektes. Die Arbeitsvorbereitung lässt sich zeitlich sowohl in der Angebotsphase (kalkulationsbegleitende Arbeitsvorbereitung), in der Vorbereitungsphase der Baustelle (von Auftragsvergabe bis Baubeginn) als auch baubegleitend einordnen.
Electrolyte-insulator-semiconductor capacitors (EISCAP) belong to field-effect sensors having an attractive transducer architecture for constructing various biochemical sensors. In this study, a capacitive model of enzyme-modified EISCAPs has been developed and the impact of the surface coverage of immobilized enzymes on its capacitance-voltage and constant-capacitance characteristics was studied theoretically and experimentally. The used multicell arrangement enables a multiplexed electrochemical characterization of up to sixteen EISCAPs. Different enzyme coverages have been achieved by means of parallel electrical connection of bare and enzyme-covered single EISCAPs in diverse combinations. As predicted by the model, with increasing the enzyme coverage, both the shift of capacitance-voltage curves and the amplitude of the constant-capacitance signal increase, resulting in an enhancement of analyte sensitivity of the EISCAP biosensor. In addition, the capability of the multicell arrangement with multi-enzyme covered EISCAPs for sequentially detecting multianalytes (penicillin and urea) utilizing the enzymes penicillinase and urease has been experimentally demonstrated and discussed.
In this work, we present a compact, bifunctional chip-based sensor setup that measures the temperature and electrical conductivity of water samples, including specimens from rivers and channels, aquaculture, and the Atlantic Ocean. For conductivity measurements, we utilize the impedance amplitude recorded via interdigitated electrode structures at a single triggering frequency. The results are well in line with data obtained using a calibrated reference instrument. The new setup holds for conductivity values spanning almost two orders of magnitude (river versus ocean water) without the need for equivalent circuit modelling. Temperature measurements were performed in four-point geometry with an on-chip platinum RTD (resistance temperature detector) in the temperature range between 2 °C and 40 °C, showing no hysteresis effects between warming and cooling cycles. Although the meander was not shielded against the liquid, the temperature calibration provided equivalent results to low conductive Milli-Q and highly conductive ocean water. The sensor is therefore suitable for inline and online monitoring purposes in recirculating aquaculture systems.
In einer Welt, die von ständiger Vernetzung und sozialen Medien geprägt ist, gibt es eine spürbare Lücke für Menschen, die sich für die »Streetwear-Culture« interessieren. Viele junge Menschen, die von Fashion, Streetwear und der damit einhergehenden Kultur fasziniert sind, stoßen in ihrem direkten Umfeld oft auf Schwierigkeiten, Gleichgesinnte zu finden. CSTHELABEL hat es sich zur Aufgabe gemacht, die lebendige Streetwear-Community zu stärken und weiter zu fördern. CSTHEMAG ist ein Projekt, das in Kollaboration mit dem Gründer von CSTHELABEL entstanden ist. Es wurde eine Nullnummer für die erste Ausgabe des Magazins konzipiert, gestaltet und produziert. Diese beinhaltet Interviews mit Content-Creatorn aus der Community, jungen Modeschöpfer:innen sowie einen Einblick in vergangene Events und Pop-Ups. Das Magazin bietet Mitwirkenden und zukünftig Interessierten einen Raum in einem für das Label neuen Medium und schafft die Möglichkeit, ihre Stimmen zu stärken. CSTHEMAG verpflichtet sich gegenüber der lebendigen Community, eine eigene Plattform zu bieten, auf der ihre einzigartigen Talente, Geschichten und Inspirationen zum Ausdruck kommen.
Pulmonary arterial cannulation is a common and effective method for percutaneous mechanical circulatory support for concurrent right heart and respiratory failure [1]. However, limited data exists to what effect the positioning of the cannula has on the oxygen perfusion throughout the pulmonary artery (PA). This study aims to evaluate, using computational fluid dynamics (CFD), the effect of different cannula positions in the PA with respect to the oxygenation of the different branching vessels in order for an optimal cannula position to be determined. The four chosen different positions (see Fig. 1) of the cannulas are, in the lower part of the main pulmonary artery (MPA), in the MPA at the junction between the right pulmonary artery (RPA) and the left pulmonary artery (LPA), in the RPA at the first branch of the RPA and in the LPA at the first branch of the LPA.
Im Hinblick auf die Klimaziele der Bundesrepublik Deutschland konzentriert sich das Projekt Diggi Twin auf die nachhaltige Gebäudeoptimierung. Grundlage für eine ganzheitliche Gebäudeüberwachung und -optimierung bildet dabei die Digitalisierung und Automation im Sinne eines Smart Buildings. Das interdisziplinäre Projekt der FH Aachen hat das Ziel, ein bestehendes Hochschulgebäude und einen Neubau an klimaneutrale Standards anzupassen. Im Rahmen des Projekts werden bekannte Verfahren, wie das Building Information Modeling (BIM), so erweitert, dass ein digitaler Gebäudezwilling entsteht. Dieser kann zur Optimierung des Gebäudebetriebs herangezogen werden, sowie als Basis für eine Erweiterung des Bewertungssystems Nachhaltiges Bauen (BNB) dienen. Mithilfe von Sensortechnologie und künstlicher Intelligenz kann so ein präzises Monitoring wichtiger Gebäudedaten erfolgen, um ungenutzte Energieeinsparpotenziale zu erkennen und zu nutzen. Das Projekt erforscht und setzt methodische Erkenntnisse zu BIM und digitalen Gebäudezwillingen praxisnah um, indem es spezifische Fragen zur Energie- und Ressourceneffizienz von Gebäuden untersucht und konkrete Lösungen für die Gebäudeoptimierung entwickelt.
The deformation and damage laws of non-homogeneous irregular structural planes in rocks are the basis for studying the stability of rock engineering. To investigate the damage characteristics of rock containing non-parallel fissures, uniaxial compression tests and numerical simulations were conducted on sandstone specimens containing three non-parallel fissures inclined at 0°, 45° and 90° in this study. The characteristics of crack initiation and crack evolution of fissures with different inclinations were analyzed. A constitutive model for the discontinuous fractures of fissured sandstone was proposed. The results show that the fracture behaviors of fissured sandstone specimens are discontinuous. The stress–strain curves are non-smooth and can be divided into nonlinear crack closure stage, linear elastic stage, plastic stage and brittle failure stage, of which the plastic stage contains discontinuous stress drops. During the uniaxial compression test, the middle or ends of 0° fissures were the first to crack compared to 45° and 90° fissures. The end with small distance between 0° and 45° fissures cracked first, and the end with large distance cracked later. After the final failure, 0° fissures in all specimens were fractured, while 45° and 90° fissures were not necessarily fractured. Numerical simulation results show that the concentration of compressive stress at the tips of 0°, 45° and 90° fissures, as well as the concentration of tensile stress on both sides, decreased with the increase of the inclination angle. A constitutive model for the discontinuous fractures of fissured sandstone specimens was derived by combining the logistic model and damage mechanic theory. This model can well describe the discontinuous drops of stress and agrees well with the whole processes of the stress–strain curves of the fissured sandstone specimens.
Welche Vorteile bietet die Forschungsdatenmanagement-Plattform Coscine für die Verwaltung von Daten in Forschungsprojekten? Hierzu gibt die Handreichung einen schnellen Überblick über den landesgeförderten Dienst Coscine für Forschende und FDM-Service-Personal an HAW in NRW (DH.NRW-Hochschulen).
FDM-Service-Mitarbeitende können die Handreichung in ihrer Beratung zu Coscine einsetzen und mit der Eingabemaske in der Kopfzeile des Dokuments auf ihre Hochschule anpassen.
We consider the numerical approximation of second-order semi-linear parabolic stochastic partial differential equations interpreted in the mild sense which we solve on general two-dimensional domains with a C² boundary with homogeneous Dirichlet boundary conditions. The equations are driven by Gaussian additive noise, and several Lipschitz-like conditions are imposed on the nonlinear function. We discretize in space with a spectral Galerkin method and in time using an explicit Euler-like scheme. For irregular shapes, the necessary Dirichlet eigenvalues and eigenfunctions are obtained from a boundary integral equation method. This yields a nonlinear eigenvalue problem, which is discretized using a boundary element collocation method and is solved with the Beyn contour integral algorithm. We present an error analysis as well as numerical results on an exemplary asymmetric shape, and point out limitations of the approach.
Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs’ flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.
Direct sampling method via Landweber iteration for an absorbing scatterer with a conductive boundary
(2024)
In this paper, we consider the inverse shape problem of recovering isotropic scatterers with a conductive boundary condition. Here, we assume that the measured far-field data is known at a fixed wave number. Motivated by recent work, we study a new direct sampling indicator based on the Landweber iteration and the factorization method. Therefore, we prove the connection between these reconstruction methods. The method studied here falls under the category of qualitative reconstruction methods where an imaging function is used to recover the absorbing scatterer. We prove stability of our new imaging function as well as derive a discrepancy principle for recovering the regularization parameter. The theoretical results are verified with numerical examples to show how the reconstruction performs by the new Landweber direct sampling method.
N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC–MS and NMR.
Biomass from various types of organic waste was tested for possible use in hydrogen production. The composition consisted of lignified samples, green waste, and kitchen scraps such as fruit and vegetable peels and leftover food. For this purpose, the enzymatic pretreatment of organic waste with a combination of five different hydrolytic enzymes (cellulase, amylase, glucoamylase, pectinase and xylase) was investigated to determine its ability to produce hydrogen (H2) with the hydrolyzate produced here. In course, the anaerobic rod-shaped bacterium T. neapolitana was used for H2 production. First, the enzymes were investigated using different substrates in preliminary experiments. Subsequently, hydrolyses were carried out using different types of organic waste. In the hydrolysis carried out here for 48 h, an increase in glucose concentration of 481% was measured for waste loads containing starch, corresponding to a glucose concentration at the end of hydrolysis of 7.5 g·L−1. In the subsequent set fermentation in serum bottles, a H2 yield of 1.26 mmol H2 was obtained in the overhead space when Terrific Broth Medium with glucose and yeast extract (TBGY medium) was used. When hydrolyzed organic waste was used, even a H2 yield of 1.37 mmol could be achieved in the overhead space. In addition, a dedicated reactor system for the anaerobic fermentation of T. neapolitana to produce H2 was developed. The bioreactor developed here can ferment anaerobically with a very low loss of produced gas. Here, after 24 h, a hydrogen concentration of 83% could be measured in the overhead space.
Analyzing electroencephalographic (EEG) time series can be challenging, especially with deep neural networks, due to the large variability among human subjects and often small datasets. To address these challenges, various strategies, such as self-supervised learning, have been suggested, but they typically rely on extensive empirical datasets. Inspired by recent advances in computer vision, we propose a pretraining task termed "frequency pretraining" to pretrain a neural network for sleep staging by predicting the frequency content of randomly generated synthetic time series. Our experiments demonstrate that our method surpasses fully supervised learning in scenarios with limited data and few subjects, and matches its performance in regimes with many subjects. Furthermore, our results underline the relevance of frequency information for sleep stage scoring, while also demonstrating that deep neural networks utilize information beyond frequencies to enhance sleep staging performance, which is consistent with previous research. We anticipate that our approach will be advantageous across a broad spectrum of applications where EEG data is limited or derived from a small number of subjects, including the domain of brain-computer interfaces.
In this paper, the use of reinforcement learning (RL) in control systems is investigated using a rotatory inverted pendulum as an example. The control behavior of an RL controller is compared to that of traditional LQR and MPC controllers. This is done by evaluating their behavior under optimal conditions, their disturbance behavior, their robustness and their development process. All the investigated controllers are developed using MATLAB and the Simulink simulation environment and later deployed to a real pendulum model powered by a Raspberry Pi. The RL algorithm used is Proximal Policy Optimization (PPO). The LQR controller exhibits an easy development process, an average to good control behavior and average to good robustness. A linear MPC controller could show excellent results under optimal operating conditions. However, when subjected to disturbances or deviations from the equilibrium point, it showed poor performance and sometimes instable behavior. Employing a nonlinear MPC Controller in real time was not possible due to the high computational effort involved. The RL controller exhibits by far the most versatile and robust control behavior. When operated in the simulation environment, it achieved a high control accuracy. When employed in the real system, however, it only shows average accuracy and a significantly greater performance loss compared to the simulation than the traditional controllers. With MATLAB, it is not yet possible to directly post-train the RL controller on the Raspberry Pi, which is an obstacle to the practical application of RL in a prototyping or teaching setting. Nevertheless, RL in general proves to be a flexible and powerful control method, which is well suited for complex or nonlinear systems where traditional controllers struggle.
Positionssensorvorrichtung
(2024)
Die Erfindung betrifft eine Positionssensorvorrichtung zur Bestimmung einer Absolutposition eines beweglichen ersten Teils relativ zu einem ortsfesten zweiten Teil mit einem mit dem beweglichen ersten Teil gekoppelter Codekörper, der dazu eingerichtet ist, eine Codespur mit einer Mehrzahl von in Spurrichtung aufeinanderfolgenden Codeelementen zu enthalten zur Bildung eines Codewortes, mit einer magnetischen Detektionseinrichtung zur Detektion der Codespur, wobei die Detektionseinrichtung zum einen an dem Codekörper befestigte und entlang der Spurrichtung in einem solchen Abstand gegenpolig zueinander angeordnete Permanentmagneten aufweist, dass der Abstand mit einer vorgegebenen Länge der jeweiligen Codeelemente übereinstimmt, und zum anderen eine Anzahl von ortsfest und quer zu dem Codekörper versetzt
angeordnete Wiegandsensoren aufweist, wobei der Abstand des Wiegandsensors zu einer Erstreckungsebene der Permanentmagneten derart gewählt ist, dass bei Überdeckung des Wiegandsensors durch den Permanentmagneten ein Wiegandpuls in dem Wiegandsensor induziert wird.
This paper serves as an introduction to the ECTS monitoring system and its potential applications in higher education. It also emphasizes the potential for ECTS monitoring to become a proactive system, supporting students by predicting academic success and identifying groups of potential dropouts for tailored support services. The use of the nearest neighbor analysis is suggested for improving data analysis and prediction accuracy.
This easy-to-understand introduction to SAP S/4HANA guides you through the central processes in sales, purchasing and procurement, finance, production, and warehouse management using the model company Global Bike. Familiarize yourself with the basics of business administration, the relevant organizational data, master data, and transactional data, as well as a selection of core business processes in SAP. Using practical examples and tutorials, you will soon become an SAP S/4HANA professional!
Tutorials and exercises for beginners, advanced users, and experts make it easy for you to practice your new knowledge. The prerequisite for this book is access to an SAP S/4HANA client with Global Bike version 4.1.
- Business fundamentals and processes in the SAP system
- Sales, purchasing and procurement, production, finance, and warehouse management
- Tutorials at different qualification levels, exercises, and recap of case studies
- Includes extensive download material for students, lecturers, and professors
Humic substances possess distinctive chemical features enabling their use in many advanced applications, including biomedical fields. No chemicals in nature have the same combination of specific chemical and biological properties as humic substances. Traditional medicine and modern research have demonstrated that humic substances from different sources possess immunomodulatory and anti-inflammatory properties, which makes them suitable for the prevention and treatment of chronic dermatoses, allergic rhinitis, atopic dermatitis, and other conditions characterized by inflammatory and allergic responses [1-4]. The use of humic compounds as agentswith antifungal and antiviral properties shows great potential [5-7].
Bald eine Dekade ist es her, dass diese annähernd mantraartig wiederholte Phrase Unternehmen zur Umsetzung datenschutzrechtlicher Vorgaben incentivierte. Was ist davon geblieben? Nur wenige in Deutschland verhängte Bußgelder erreichten Millionenhöhe. Hintergrund ist (auch) das deutsche Ordnungswidrigkeitenrecht, welches in einem Spannungsverhältnis zu den Vorgaben der DS-GVO steht. Ein Bußgeldbescheid der Berliner Datenschutzaufsicht gegen die Deutsche Wohnen sollte Auslöser eines langen, fortdauernden Rechtsstreits werden. Auf Vorlage des KG hatte der EuGH in der Rechtssache C-807/21 („Deutsche Wohnen“) erstmals Gelegenheit, sich zur Frage der Bußgeldhaftung zu positionieren.
Das Thema Datenschutz wurde bei der öffentlichen Auftragsvergabe bislang vor allem in Bezug auf Drittlandtransfers personenbezogener Daten in die USA diskutiert. Jedoch spielt der Datenschutz für das Vergabeverfahren und für die Ausführung datenschutzrelevanter Leistungen generell eine wesentliche Rolle. Gleichwohl herrschen bislang unter öffentlichen Auftraggebern Schwierigkeiten, datenschutzrechtlich relevante Fallkonstellationen zu erkennen, die möglichen Risiken daraus abzuleiten und, sofern dies gelingt, diesen Risiken angemessen zu begegnen. Der vorliegende Beitrag befasst sich mit der datenschutzrechtlichen Verantwortlichkeit, ihren Folgen und den daraus resultierenden Konsequenzen für die Gestaltung von Vergabeverfahren und Vergabeunterlagen.
The “1. Stokes’ problem”, the “suddenly accelerated flat wall”, is the oldest application of the Navier-Stokes equations. Stokes’ solution of the “problem” does not comply with the mathematical theorem of Cauchy and Kowalewskaya on the “Uniqueness and Existence” of solutions of partial differential equations and violates the physical theorem of minimum entropy production/dissipation of the Thermodynamics of Irreversible Processes. The result includes very high local shear stresses and dissipation rates. That is of special interest for the theory of turbulent and mixed turbulent/laminar flow. A textbook solution of the “1. Stokes Problem” is the Couette flow, which has a constant sheer stress along a linear profile. A consequence is that the Navier-Stokes equations do not describe any S-shaped part of a turbulent profile found in any turbulent Couette experiment. The paper surveys arguments referring to that statement, concerning the history of >150 years. Contrary to this there is always a Navier-Stokes solution near the wall, observed by a linear part of the Couette profile. There a turbulent description (e.g. by the logarithmic law-of-the-wall) fails completely. That is explained by the minimum dissipation requirement together with the Couette feature τ = const. The local co-existence of a turbulent zone and a laminar zone near the wall is stable and observed also at high Reynolds-Numbers.
n diesem Kapitel werden die Abrechnungsvorschriften wichtiger ATV kurz, aber umfassend zusammengestellt. Einigen Abrechnungsbestimmungen für Einzelleistungen, die keine Nebenleistungen sind ((siehe DIN 18299 und Abschnitt 4 der jeweiligen ATV), sind mit aufgenommen worden; die ATV enthalten jedoch weitergehende Festlegungen über Nebenleistungen und Besondere Leistungen.
Im Anschluss folgen Hinweise zu den Toleranzen im Hochbau sowie im Straßenbau.
Die fotografische Arbeit "Almanya" veranschaulicht Teilaspekte der türkischen Kultur anhand von Repräsentantinnen und Repräsentanten der türkeistämmigen Community in Deutschland. Mit einem Fokus auf Kulinarik und Formen des Zusammenlebens werden Menschen mit türkischen Wurzeln porträtiert, sodass am Ende ein Einblick in deren Lebens- und Gedankenwelt ermöglicht wird und kulinarische Brücken zwischen Deutschen und der türkischen Kultur gebaut werden. Die enthaltene Botschaft, welche das Projekt den Rezipient:innen überbringt, ist in einem multikulturellen Land wie Deutschland von großer Wichtigkeit für gegenseitiges Verständnis und bildet den Boden für ein harmonisches Miteinander.
Bringing brand experience to marketplaces : ein Online-Marktplatz, der Konsument und Marke verbindet
(2024)
«Keno» zeigt ein Konzept für einen Online-Marktplatz im Fashion-Segment, mit Fokus auf individueller Beratung, digitaler Anprobe und visueller sowie informativer Präsentation der Marken. Marktplätze werden aufgrund von großer Auswahl und Vertrauenswürdigkeit von Konsument:innen bevorzugt aufgesucht. Durch die immersive Darstellung an einem maßgetreuen Avatar und die Einbindung der Marke in das Einkaufserlebnis soll hier die Zahl der Retouren verringert und die Kund:innenzufriedenheit gesteigert werden. Mittels nutzerorientierter Strategien und der Gestaltung eines Designsystems bekam «Keno» seinen Look. Dabei fanden modernste Techniken wie künstliche Intelligenzen und Design Token Systeme Verwendung. Das Projekt zeigt letztendlich Möglichkeiten auf, wie ein Marktplatz durch Brand Experience, Onlineshopping-Wege verkürzen und zu mehr Nachhaltigkeit im E-Commerce beitragen kann.
Das Projekt "ARRK Journeys" entwickelt ein neues Dokumentarfilm-Format, das darauf abzielt, potenzielle Mitarbeiter für die ARRK Engineering GmbH zu gewinnen
Das Ziel des Projekts ist es, die Vielfalt an Karrieremöglichkeiten bei der ARRK Engineering GmbH aufzuzeigen und die Attraktivität des Unternehmens als Arbeitgeber zu betonen. Durch individuelle Mitarbeitergeschichten werden die Fragen beantwortet, warum eine berufliche Laufbahn bei ARRK erstrebenswert ist, ob jeder die Möglichkeit hat, bei ARRK zu arbeiten, und welche Entwicklungsmöglichkeiten das Unternehmen bietet. "ARRK Journeys" betont das Wohlbefinden der Mitarbeiter und ihre persönliche Bindung zum Unternehmen, um eine positive Arbeitgebermarke zu schaffen.
"ARRK Journeys" präsentiert die ARRK Engineering GmbH als attraktiven Arbeitgeber und inspiriert potenzielle Mitarbeiter dazu, ihren eigenen Weg zu finden.
Baustoffe
(2024)
A novel method to determine the extruded length of a metallic wire for a directed energy deposition (DED) process using a microwave (MW) plasma jet with a straight-through wire feed is presented. The method is based on the relative comparison of the measured frequency response obtained by the large-signal scattering parameter (Hot-S) technique. In the practical working range, repeatability of less than 6% for a nonactive plasma and 9% for the active plasma state is found. Measurements are conducted with a focus on a simple solution to decrease the processing time and reduce the integration time of the process into the existing hardware. It is shown that monitoring a single frequency for magnitude and phase changes is sufficient to achieve good accuracy. A combination of different measurement values to determine the length is possible. The applicability to different diameter of the same material is shown as well as a contact detection of the wire and metallic substrate.
Dieses Projekt hat zum Ziel, umfassend über Climate Engineering-Maßnahmen zu informieren und dabei insbesondere ihre Funktionsweise, Kosten und Risiken darzustellen. Die entstandene Plattform "Die Erde abkühlen!" bietet einen Einblick in die Lösungsansätze des Climate Engineerings durch die Verwendung von Storytelling. Sie ermöglicht Nutzer:innen einen Überblick über den aktuellen Stand der Klimaerwärmung sowie den Vergleich von Climate Engineering-Maßnahmen. Ein entwickeltes Bewertungssystem auf Grundlage der "Royal Society" sowie interaktive Infografiken geben Nutzer:innen einen umfassenden Einblick. Das Hauptziel des Projekts ist die digitale Transformation der Climate Engineering-Lösungsansätze. Dabei geht es nicht nur darum, über die Folgen der Klimaerwärmung zu informieren, sondern auch konkrete Lösungen aufzuzeigen. Durch die Entwicklung eines innovativen Storytellings wird die Thematik nicht nur dramaturgisch präsentiert, sondern ermöglicht es den Nutzer:innen auch, ihre eigene Wissensvertiefung zu steuern.
Durch das öffentliche Baurecht werden die Zulässigkeit, die Grenzen, die Ordnung und die Förderung der baulichen Nutzung des Bodens geregelt.
Die Ausschreibung und die Vergabe sind von essenzieller Bedeutung für ein Bauvorhaben und werden deshalb in der HOAI mit zwei Leistungsphasen abgebildet: nämlich mit der Leistungsphase 6 Vorbereitung der Vergabe sowie der Leistungsphase 7 Mitwirkung bei der Vergabe. Im Zuge der Ausschreibung und der Vergabe werden die für den AG anfallenden Kosten festgelegt und bilden somit die letzte größere Stellschraube für Preiseinsparungen.