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Inhalt
07 Der Stoff, aus dem die Träume sind | Modedesigner, Fotograf, Künstler : der FH-Absolvent Hans W. Krämer
12 Wurzeln, die tief zurückreichen | Die Handwerker- und Kunstgewerbeschule Aachen
18 Eine einmalige Chance | Der japanische Gastwissenschaftler Prof. Dr. Ko-ichiro Miyamoto forscht ein Jahr lang am Campus Jülich
22 Pionierarbeit auf leisen Sohlen | Vier junge Marokkanerinnen sind die ersten Absolventinnen des internationalen Studiengangs Angewandte Chemie
26 Gute Hacker - Böse Hacker| FH Aachen bietet Kurse zum ethischen Hacken an
28 Eiffelturm meets Kartenhaus | Architekturstudierende entwickeln ausgefuchstes Stecksystem für temporäre Architektur
32 Dom in 3-D | Fachbereich Bauingenieurwesen vermisst das Aachener Welterbe
36 "Müssen Behinderte denn Auto fahren?!" | FH-Absolventinnen gründen Fahrschule für Menschen mit Handicap
40 Im Innern des "Blutenden Gletschers" | Fünf Wochen lang lebten und arbeiteten FH-Ingenieure in der größten Eiswüste der Erde
46 Das ist mein Zuhause | Nach über 40 Jahren verlässt Prof. Dr. Horst Heinrichs die FH Aachen
50 Die Qual der Wahl | Mit dem "Guten Studienstart" ins Ingenieurstudium
52 Fachtutorenschulung an der FH Aachen
55 Zusammen wachsen | Neue Schnittstelle: Erste Studierende machen ihren Master in Energiewirtschafts-Informatik
56 Pro8 geht in die achte Runde | Studierende stellen sich Herausforderungen aus der Industrie
58 Auf die Messe, fertig, los! | Alumnus Moritz Christ gibt der Euregio Wirtschaftsschau ein neues Gesicht
61 Unsere EM wird 75: Die FH wünscht alles Gute!
61 Herzlichen Glückwunsch! Alt-Rektor Prof. Buchkremer wird 75
62 FH Aachen kooperiert mit Ford | Hannover Messe: FH präsentiert drei Projekte | FH Aachen ausgezeichnet : Zertifikat 2014 Vielfalt gestalten in NRW
63 Impressum
Miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge favor the semiconductor field-effect platform as one of the most attractive approaches for the development of label-free DNA chips. In this work, a capacitive field-effect EIS (electrolyte–insulator–semiconductor) sensor covered with a layer-by-layer prepared, positively charged weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was used for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization. The negatively charged probe single-stranded DNA (ssDNA) molecules were electrostatically adsorbed onto the positively charged PAH layer, resulting in a preferentially flat orientation of the ssDNA molecules within the Debye length, thus yielding a reduced charge-screening effect and a higher sensor signal. Each sensor-surface modification step (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), reducing an unspecific adsorption by a blocking agent, incubation with noncomplementary DNA (ncDNA) solution) was monitored by means of capacitance–voltage and constant-capacitance measurements. In addition, the surface morphology of the PAH layer was studied by atomic force microscopy and contact-angle measurements. High hybridization signals of 34 and 43 mV were recorded in low-ionic strength solutions of 10 and 1 mM, respectively. In contrast, a small signal of 4 mV was recorded in the case of unspecific adsorption of fully mismatched ncDNA. The density of probe ssDNA and dsDNA molecules as well as the hybridization efficiency was estimated using the experimentally measured DNA immobilization and hybridization signals and a simplified double-layer capacitor model. The results of field-effect experiments were supported by fluorescence measurements, verifying the DNA-immobilization and hybridization event.
Capacitive field-effect electrolyte-insulator-semiconductor sensors consisting of an Al-p-Si-SiO2 structure have been used for the electrical detection of unlabelled single- and double-stranded DNA (dsDNA) molecules by their intrinsic charge. A simple functionalization protocol based on the layer-by-layer (LbL) technique was used to prepare a weak polyelectrolyte/probe-DNA bilayer, followed by the hybridization with complementary target DNA molecules. Due to the flat orientation of the LbL-adsorbed DNA molecules, a high sensor signal has been achieved. In addition, direct label-free detection of in-solution hybridized dsDNA molecules has been studied.
Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.
Mechatronics consist of the integration of mechanical
engineering, electronic integration and computer science/
engineering. These broad fields are essential for robotic
systems, yet it makes it difficult for the researchers to specialize
and be experts in all these fields. Collaboration between
researchers allow for the integration of experience and specialization,
to allow optimized systems. Collaboration between the
European countries and South Africa is critical, as each country
has different resources available, which the other countries
might not have. Applications with the need for approval of
any restrictions, can also be obtained easier in some countries
compared to others, thus preventing the delays of research.
Some problems that have been experienced are discussed, with
the Robotics Center of South Africa as a possible solution.
The conference center darmstadtium in Darmstadt is a prominent example of energy efficient buildings. Its heating system consists of different source and consumer circuits connected by a Zortström reservoir. Our goal was to reduce the energy costs of the system as much as possible. Therefore, we analyzed its supply circuits. The first step towards optimization is a complete examination of the system: 1) Compilation of an object list for the system, 2) collection of the characteristic curves of the components, and 3) measurement of the load profiles of the heat and volume-flow demand. Instead of modifying the system manually and testing the solution by simulation, the second step was the creation of a global optimization program. The objective was to minimize the total energy costs for one year. We compare two different topologies and show opportunities for significant savings.
A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.
Workshop Formine 2015 mit Projekten von Antonia Zajgia, Arnoud Charoy, Laura Viktoria Koch, Kai Stein, Ferdinand Klopfer, Florian D. Heinz, Tobias Scholz, Moritz Gnädinger, Pablo Raphael, Franko Scheuplein, Thomas Tünnemann, René Großner, Anny Phung, Mylenne Jakob-Wendel, Kira Joerißen, Florian Erber, Julian Wesse und Isolde Nagel
Geotechnik
(2015)
In der nationalen und der europäischen Normung werden die geotechnischen Aufgaben zwecks Mindestanforderungen an Baugrunduntersuchung, rechnerische Nachweise und Überwachung der Ausführung in drei Klassen (Kategorien) eingeteilt. Sie richten sich nach der zu erwartenden Reaktion des Baugrundes, nach dem geotechnischen Schwierigkeitsgrad des Tragwerks und seiner Einflüsse auf die Umgebung.
In DIN 4020 wurde die Einteilung bezüglich Art und Umfang der geotechnischen Untersuchungen bereits verbindlich eingeführt.
Geotechnik
(2015)
Globale Stabilitätsanalysen zylindrischer, seismisch belasteter Tanks auf numerischer Grundlage
(2015)
Manuelle Herstellung ist sozial fair, ökologisch nachhaltig und schafft qualitätsvolle Erzeugnisse! Vorbote für eine großformatige Rückkehr zum Handwerk und zur eigenhändigen Fertigung ist die Maker-Bewegung! – Solche Thesen begegnen uns gegenwärtig oft. Journalistische Texte, Filmdokumentationen, Werbung oder die Ästhetik von Produkten sind ihre Vehikel. Doch wie ist es um die Wiederbelebung des Handwerks tatsächlich bestellt? Und in welchem Verhältnis steht das Design – ein durch und durch industriebasiertes Berufsfeld – zu vorindustriellen Produktionsweisen? Diesen Fragen geht das vorliegende Buch ebenso auf den Grund wie der seit Beginn der Industrialisierung auftretenden Handwerksromantik. Es untersucht zudem, wie aktuelles Design die Sehnsucht nach dem Ursprünglichen mit formalen Kodes beantwortet und wie die visuellen Erscheinungsformen des Handgemachten ihre Wirkung freisetzen.