Elsevier
Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (183)
- INB - Institut für Nano- und Biotechnologien (105)
- IfB - Institut für Bioengineering (65)
- Fachbereich Chemie und Biotechnologie (57)
- Fachbereich Luft- und Raumfahrttechnik (35)
- Fachbereich Energietechnik (29)
- Fachbereich Maschinenbau und Mechatronik (16)
- Fachbereich Bauingenieurwesen (14)
- Solar-Institut Jülich (14)
- Fachbereich Elektrotechnik und Informationstechnik (9)
Has Fulltext
- no (350) (remove)
Document Type
- Article (328)
- Part of a Book (12)
- Conference Proceeding (9)
- Other (1)
Keywords
- Earthquake (4)
- LAPS (4)
- Gamification (3)
- Heparin (3)
- Central receiver power plant (2)
- Central receiver system (2)
- Chemometrics (2)
- Concentrated solar collector (2)
- Concentrated systems (2)
- Field-effect sensor (2)
- Gas turbine (2)
- IR spectroscopy (2)
- Light-addressable potentiometric sensor (2)
- NMR spectroscopy (2)
- Solar concentration (2)
- Standardization (2)
- hydrogen peroxide (2)
- (Bio)degradation (1)
- Active humidity control (1)
- Adaptive Systems (1)
- Adaptive control (1)
- Additive Manufacturing (1)
- Additive manufacturing (1)
- Alginate beads (1)
- Alzheimer's disease (1)
- Anastomotic leakage (1)
- Assembly (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Augmented Reality (1)
- Authenticity (1)
- Autolysis (1)
- Automatic control (1)
- Avalanche (1)
- Bacillus atrophaeus (1)
- Binder Jetting (1)
- Biocomposites (1)
- Biomass (1)
- Bootstrapping (1)
- Borehole heat exchanger (1)
- CNOT (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Cardiac tissue (1)
- Cell permeability (1)
- CellDrum (1)
- Cellular force (1)
- Censored data (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Chimeric liver-humanized mice (1)
- Coal (1)
- Collective risk model (1)
- Competitiveness (1)
- Computational biomechanics (1)
- Concentrating solar power (1)
- Constitutive model (1)
- Contractile tension (1)
- Cross border adjustment mechanism (1)
- Crude heparin (1)
- C–V method (1)
- DLR-ESTEC GOSSAMER roadmap for solar sailing (1)
- DNA biosensor (1)
- DNA hybridization (1)
- Damage mechanics theory (1)
- Decomposition (1)
- Decoupling (1)
- Dehydrogenase (1)
- Detergent protease (1)
- Deuterated solvents (1)
- Deuterium NMR (1)
- Diaphorase (1)
- Digital Twin (1)
- Dimensional splitting (1)
- Directed Energy Deposition (1)
- Discontinuous fractures (1)
- Drinfeld modules (1)
- Drug distribution (1)
- Drug metabolism (1)
- Drug simulation (1)
- Dry-low-NOx (DLN) combustion (1)
- Dynamic simulation (1)
- E-Mobility (1)
- EGG (1)
- EIS capacitive sensor (1)
- Electrochemical impedance spectroscopy (1)
- Electrolyte–insulator–semiconductor (1)
- Electromechanical modeling (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Energy-intensive industry (1)
- Enzymatic biosensor (1)
- Enzyme logic gate (1)
- Error Recovery (1)
- Exponential time differencing (1)
- External knee adduction moments (1)
- Extracellular enzymes (1)
- Fault detection (1)
- Field effect (1)
- Finite differences (1)
- Finite element analysis (1)
- Finite element modelling (1)
- Floor prices (1)
- Fracture classification (1)
- Frame structure (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Fresnel collector (1)
- Fresnel power plant (1)
- Fuel cell (1)
- GOSSAMER-1 (1)
- Gamma distribution (1)
- Goodness-of-fit test (1)
- H2 (1)
- Hazard assessment (1)
- Health management system (1)
- Heat transport (1)
- High hydrogen combustion (1)
- Higher derivations (1)
- Hodgkin–Huxley models (1)
- Homogenization (1)
- Human-Computer interaction (1)
- Humidity (1)
- Hybridization (1)
- Hydrogen combustion (1)
- Hydrogen gas turbine (1)
- Hydrogen peroxide (1)
- Hydrogenotrophic methanogens (1)
- Hypersecretion (1)
- INSYSME (1)
- Imaging (1)
- Impedance analysis (1)
- Impedance spectroscopy (1)
- In-plane performance, isolation (1)
- Independence test (1)
- Infill wall design (1)
- Inorganic ions (1)
- Interplanetary flight (1)
- Interstellar objects (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Ions (1)
- Iterative learning control (1)
- Knockout mice (1)
- L-PBF (1)
- LPBF (1)
- Label-free detection (1)
- Landslide tsunamis (1)
- Large scale tests (1)
- Larynx position (1)
- Laser-Powder Bed Fusion (1)
- Layer-by-layer adsorption (1)
- Level system (1)
- Light-addressable Potentiometric Sensor (1)
- Lipopolysaccharide (1)
- Liver (1)
- Low-field NMR (1)
- Manipulated variables (1)
- Marker-free mutagenesis (1)
- Masonry infill (1)
- Masonry partition walls (1)
- Matrix exponential (1)
- Methane (1)
- Methanogenesis (1)
- Micromix combustion (1)
- Mild cognitive impairment (1)
- Missions (1)
- Mobility transition (1)
- Molecular modelling (1)
- Molecular weight determination (1)
- Molten salt receiver system (1)
- Molten salt solar tower (1)
- Morphing (1)
- Multi-criteria decision analysis (1)
- Multi-storey (1)
- Musculoskeletal model (1)
- NMR (1)
- NMR exchange relaxometry (1)
- Natural fibres (1)
- Negative impedance convertor (1)
- Niacin (1)
- Non-model-based Evaluation (1)
- Non-parallel fissures (1)
- Numerical modelling (1)
- Online diagnostic (1)
- Optical and thermal analysis (1)
- Organic light-emitting diode display (1)
- Out-of-plane capacity (1)
- Overland flow (1)
- PEM fuel cell (1)
- PLS-regression (1)
- Parametric bootstrap (1)
- Periods (1)
- Piping (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polymer-matrix composites (1)
- Powder Material (1)
- Power conversion systems (1)
- Preference assessment (1)
- Principal component analysis (1)
- Probability distribution mapping (1)
- Product-integration (1)
- Proper Orthogonal Decomposition (1)
- Pulsations (1)
- Q-criterion (1)
- Quality control (1)
- Quantum chemistry (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Regionalization (1)
- Rehabilitation engineering (1)
- Reinforced concrete frame (1)
- Relative air humidity (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Seismic loading (1)
- Semi-parametric random censorship model (1)
- Shoulder (1)
- Simultaneous determination (1)
- Slab deflection (1)
- Small spacecraft (1)
- Snow (1)
- Soft independent modeling of class analogy (1)
- Solar dish (1)
- Solar sail (1)
- Solitary waves (1)
- Spacecraft (1)
- Spleen (1)
- Steel industry (1)
- Stenotrophomonas maltophilia (1)
- Sterilisation process (1)
- Stress concentrations (1)
- Support System (1)
- Surgical staplers (1)
- Survival analysis (1)
- Tank (1)
- Thiamine (1)
- Tomography (1)
- Toxicology (1)
- Trajectories (1)
- Transcendence (1)
- Transfer impedance (1)
- Transient flux distribution (1)
- Two-phase modelling (1)
- USP (1)
- Uniaxial compression test (1)
- Uracil-phosphoribosyltransferase (1)
- User study (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vasomotions (1)
- Virtual reality (1)
- Vitamin A (1)
- Vitamin B (1)
- Voice assessment (1)
- Volterra integral equation (1)
- XOR (1)
- anaesthetic complications (1)
- barium strontium titanate (1)
- calorimetric gas sensor (1)
- coherent structures (1)
- constructive alignment (1)
- contactless conductivity sensor (1)
- dental trauma (1)
- difficult airway (1)
- double-lumen tube intubation (1)
- enzymatic (bio)degradation (1)
- examination (1)
- field-effect sensor (1)
- hiPS cardiomyocytes (1)
- high-k material (1)
- hydraulic modelling (1)
- impedance spectroscopy (1)
- in-situ monitoring (1)
- intraclass correlation coefficient (1)
- lable-free detection (1)
- long-term retention (1)
- magnetic actuation (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- model performance (1)
- multi-functional material (1)
- multimodal (1)
- novel photoexcitation method (1)
- poly(d, l-lactic acid) (1)
- practical learning (1)
- qNMR (1)
- shoulder (1)
- spatial resolution (1)
- standard error of measurement (1)
- sterilisation (1)
- stretch reflex (1)
- superparamagnetic bead (1)
- t-modules (1)
- test-retest reliability (1)
- tilted constant illumination (1)
- videolaryngoscopy (1)
A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system.
An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.
LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.
This paper proposes an approach to the choice and evaluation of engineering models with the aid of a typical application in geotechnics. An important issue in the construction of shallow tunnels, especially in weak ground conditions, is the tunnel face stability. Various theoretical and numerical models for predicting the necessary support pressure have been put forth in the literature. In this paper, we combine laboratory experiments performed at the University of Innsbruck with current methods of uncertainty and sensitivity analysis for assessing adequacy, predictive power and robustness of the models. The major issues are the handling of the twofold uncertainty of test results and of model predictions as well as the decision about what are the influential input parameters.
Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of ‘gene-shuffled’ (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.