Article
Refine
Year of publication
Document Type
- Article (468) (remove)
Language
- English (468) (remove)
Has Fulltext
- no (468) (remove)
Keywords
- LAPS (4)
- hydrogen peroxide (3)
- Bacillus atrophaeus (2)
- Field-effect sensor (2)
- Light-addressable potentiometric sensor (2)
- Raman spectroscopy (2)
- field-effect sensor (2)
- tobacco mosaic virus (TMV) (2)
- (Bio)degradation (1)
- Bacillus atrophaeus spores (1)
- CNOT (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- C–V method (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Dehydrogenase (1)
- Diaphorase (1)
- EIS capacitive sensor (1)
- Electrolyte–insulator–semiconductor (1)
- Enzymatic biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Field effect (1)
- Field-effect biosensor (1)
- Hydrogen peroxide (1)
- Impedance spectroscopy (1)
- Label-free detection (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Light-addressable Potentiometric Sensor (1)
- MOS (1)
- Multianalyte detection (1)
- Negative impedance convertor (1)
- O2 plasma (1)
- Organic light-emitting diode display (1)
- Penicillin (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Real-time monitoring (1)
- Resonance-mode measurement (1)
- Simultaneous determination (1)
- Sn₃O₄ (1)
- Sterilisation process (1)
- TMV adsorption (1)
- Ta₂O₅ gate (1)
- XOR (1)
- annealing (1)
- artificial olfactory image (1)
- barium strontium titanate (1)
- biosensor (1)
- biosensors (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- capacitive field-effect sensor (1)
- catalytic metal (1)
- chemical sensor (1)
- contactless conductivity sensor (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electronic nose (1)
- endospores (1)
- enzymatic (bio)degradation (1)
- enzyme cascade (1)
- field-effect structure (1)
- gas sensor (1)
- glucose oxidase (GOx) (1)
- heavy metals (1)
- high-k material (1)
- horseradish peroxidase (HRP) (1)
- hydroxylation (1)
- immobilization (1)
- impedance spectroscopy (1)
- in-situ monitoring (1)
- lable-free detection (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- metal-oxide-semiconductor structure (1)
- multi-functional material (1)
- nanobelts (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organosilanes (1)
- plant virus detection (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- scanned light pulse technique (1)
- silanization (1)
- spatial resolution (1)
- sterilisation (1)
- sterilization (1)
- sterilization conditions (1)
- surface functionalization (1)
- temperature (1)
- tilted constant illumination (1)
- turnip vein clearing virus (TVCV) (1)
- visualization (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (468) (remove)
An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime
(2001)
An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer
(2017)
An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).