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On obligations in the development process of resilient systems with algorithmic design methods
(2018)
Advanced computational methods are needed both for the design of large systems and to compute high accuracy solutions. Such methods are efficient in computation, but the validation of results is very complex, and highly skilled auditors are needed to verify them. We investigate legal questions concerning obligations in the development phase, especially for technical systems developed using advanced methods. In particular, we consider methods of resilient and robust optimization. With these techniques, high performance solutions can be found, despite a high variety of input parameters. However, given the novelty of these methods, it is uncertain whether legal obligations are being met. The aim of this paper is to discuss if and how the choice of a specific computational method affects the developer’s product liability. The review of legal obligations in this paper is based on German law and focuses on the requirements that must be met during the design and development process.
Nutzen und Rahmenbedingungen 5 informationsgetriebener Geschäftsmodelle des Internets der Dinge
(2018)
Im Kontext der zunehmenden Digitalisierung wird das Internet der Dinge (englisch: Internet of Things, IoT) als ein technologischer Treiber angesehen, durch den komplett neue Geschäftsmodelle im Zusammenspiel unterschiedlicher Akteure entstehen können. Identifizierte Schlüsselakteure sind unter anderem traditionelle Industrieunternehmen, Kommunen und Telekommunikationsunternehmen. Letztere sorgen mit der Bereitstellung von Konnektivität dafür, dass kleine Geräte mit winzigen Batterien nahezu überall und direkt an das Internet angebunden werden können. Es sind schon viele IoT-Anwendungsfälle auf dem Markt, die eine Vereinfachung für Endkunden darstellen, wie beispielsweise Philips Hue Tap. Neben Geschäftsmodellen basierend auf Konnektivität besteht ein großes Potenzial für informationsgetriebene Geschäftsmodelle, die bestehende Geschäftsmodelle unterstützen sowie weiterentwickeln können. Ein Beispiel dafür ist der IoT-Anwendungsfall Park and Joy der Deutschen Telekom AG, bei dem Parkplätze mithilfe von Sensoren vernetzt und Autofahrer in Echtzeit über verfügbare Parkplätze informiert werden. Informationsgetriebene Geschäftsmodelle können auf Daten aufsetzen, die in IoT-Anwendungsfällen erzeugt werden. Zum Beispiel kann ein Telekommunikationsunternehmen Mehrwert schöpfen, indem es aus Daten entscheidungsrelevantere Informationen – sogenannte Insights – ableitet, die zur Steigerung der Entscheidungsagilität genutzt werden. Außerdem können Insights monetarisiert werden. Die Monetarisierung von Insights kann nur nachhaltig stattfinden, wenn sorgfältig gehandelt wird und Rahmenbedingungen berücksichtigt werden. In diesem Kapitel wird das Konzept informationsgetriebener Geschäftsmodelle erläutert und anhand des konkreten Anwendungsfalls Park and Joy verdeutlicht. Darüber hinaus werden Nutzen, Risiken und Rahmenbedingungen diskutiert.
Background
Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC.
Methods
A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed.
Results
A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001).
Conclusions
To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals.
This paper presents NLP Lean Programming
framework (NLPf), a new framework
for creating custom natural language processing
(NLP) models and pipelines by utilizing
common software development build systems.
This approach allows developers to train and
integrate domain-specific NLP pipelines into
their applications seamlessly. Additionally,
NLPf provides an annotation tool which improves
the annotation process significantly by
providing a well-designed GUI and sophisticated
way of using input devices. Due to
NLPf’s properties developers and domain experts
are able to build domain-specific NLP
applications more efficiently. NLPf is Opensource
software and available at https://
gitlab.com/schrieveslaach/NLPf.
Intensive poultry operation systems emit a considerable volume of inorganic and organic matter in the surrounding environment. Monitoring cleaning properties of exhaust air cleaning systems and to detect small but significant changes in emission characteristics during a fattening cycle is important for both emission and fattening process control. In the present study, we evaluated the potential of near-infrared spectroscopy (NIRS) combined with chemometric techniques as a monitoring tool of exhaust air from poultry operation systems. To generate a high-quality data set for evaluation, the exhaust air of two poultry houses was sampled by applying state-of-the-art filter sampling protocols. The two stables were identical except for one crucial difference, the presence or absence of an exhaust air cleaning system. In total, twenty-one exhaust air samples were collected at the two sites to monitor spectral differences caused by the cleaning device, and to follow changes in exhaust air characteristics during a fattening period. The total dust load was analyzed by gravimetric determination and included as a response variable in multivariate data analysis. The filter samples were directly measured with NIR spectroscopy. Principal component analysis (PCA), linear discriminant analysis (LDA), and factor analysis (FA) were effective in classifying the NIR exhaust air spectra according to fattening day and origin. The results indicate that the dust load and the composition of exhaust air (inorganic or organic matter) substantially influence the NIR spectral patterns. In conclusion, NIR spectroscopy as a tool is a promising and very rapid way to detect differences between exhaust air samples based on still not clearly defined circumstances triggered during a fattening period and the availability of an exhaust air cleaning system.