Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (1928)
- Fachbereich Elektrotechnik und Informationstechnik (1150)
- Fachbereich Wirtschaftswissenschaften (1119)
- Fachbereich Energietechnik (1066)
- Fachbereich Chemie und Biotechnologie (892)
- Fachbereich Maschinenbau und Mechatronik (801)
- Fachbereich Luft- und Raumfahrttechnik (769)
- Fachbereich Bauingenieurwesen (664)
- IfB - Institut für Bioengineering (627)
- INB - Institut für Nano- und Biotechnologien (585)
- Fachbereich Gestaltung (347)
- Solar-Institut Jülich (335)
- Fachbereich Architektur (163)
- ECSM European Center for Sustainable Mobility (113)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (66)
- Nowum-Energy (65)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (62)
- Institut fuer Angewandte Polymerchemie (32)
- Sonstiges (24)
- IBB - Institut für Baustoffe und Baukonstruktionen (21)
- Kommission für Forschung und Entwicklung (20)
- Freshman Institute (19)
- Verwaltung (11)
- Arbeitsstelle fuer Hochschuldidaktik und Studienberatung (4)
- FH Aachen (4)
- IaAM - Institut für angewandte Automation und Mechatronik (4)
- IMP - Institut für Mikrowellen- und Plasmatechnik (3)
- Kommission für Planung und Finanzen (2)
- Senat (2)
- Datenverarbeitungszentrale (1)
- Digitalisierung in Studium & Lehre (1)
Has Fulltext
- no (9284) (remove)
Language
Document Type
- Article (5518)
- Conference Proceeding (1413)
- Book (1057)
- Part of a Book (555)
- Patent (174)
- Bachelor Thesis (169)
- Report (82)
- Doctoral Thesis (79)
- Conference: Meeting Abstract (75)
- Other (67)
Keywords
- Illustration (10)
- Nachhaltigkeit (10)
- Corporate Design (9)
- Erscheinungsbild (8)
- Gamification (8)
- Redesign (7)
- Animation (6)
- Datenschutz (6)
- Deutschland (6)
- Digitalisierung (6)
Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.