Refine
Year of publication
- 2021 (56) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (56) (remove)
Document Type
- Article (39)
- Conference Proceeding (7)
- Book (2)
- Part of a Book (2)
- Doctoral Thesis (2)
- Report (2)
- Other (1)
- Preprint (1)
Keywords
- constructive alignment (2)
- examination (2)
- long-term retention (2)
- multimodal (2)
- practical learning (2)
- AlterG (1)
- Bacillus sp (1)
- Biosolubilization (1)
- Bone quality and biomechanics (1)
- Bootstrap (1)
- Boundary integral equations (1)
- Capacitive field-effect sensor (1)
- CellDrum (1)
- Coefficient of ocular rigidity (1)
- Corneo-scleral shell (1)
- Differential tonometry (1)
- EEG (1)
- Empirical process (1)
- Environmental impact (1)
- Eyeball (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Glaucoma (1)
- Hadamard differentiability (1)
- Helmholtz equation (1)
- Impedance Spectroscopy (1)
- Interior Neumann eigenvalues (1)
- LPS (1)
- Label-free detection (1)
- Langevin theory (1)
- Machine learning (1)
- Magnetic nanoparticles (1)
- Micromagnetic simulation (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Natural language processing (1)
- Neuromuskuläres System (1)
- Nonequilibrium dynamics (1)
- Numerics (1)
- Ocular blood flow (1)
- Paired sample (1)
- Plant virus (1)
- Potential theory (1)
- Pressure-volume relationship (1)
- Process model (1)
- RVA (1)
- Rehabilitationsmedizin (1)
- Rehabilitatives Training (1)
- Robotik (1)
- Septic cardiomyopathy (1)
- Simulation (1)
- Skeletal muscle (1)
- Sleep EEG (1)
- Small Aral Sea (1)
- Stiffness (1)
- TMV adsorption (1)
- Ta₂O₅ gate (1)
- Tendon Rupture (1)
- Tendons (1)
- Tobacco mosaic virus (TMV) (1)
- Trainingsgerät (1)
- Ultrasound (1)
- Vascular response (1)
- Visual field asymmetry (1)
- Zeta potential (1)
- acetoin (1)
- acetoin reductase (1)
- actin cytoskeleton (1)
- alcoholic beverages (1)
- bioburdens (1)
- biopotential electrodes (1)
- biosensors (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive field-effect sensor (1)
- capacitive field-effect sensors (1)
- cardiomyocyte biomechanics (1)
- drop jump (1)
- ecological structure (1)
- enzymatic biosensor (1)
- gait (1)
- graphene oxide (1)
- humic acid (1)
- hyper-gravity (1)
- hypo-gravity (1)
- intraclass correlation coefficient (1)
- layer-by-layer technique (1)
- lignite (1)
- locomotion (1)
- metagenomics (1)
- microbial diversity (1)
- muscle fascicle behavior (1)
- muscle mechanics (1)
- nanomaterials (1)
- parabolic flight (1)
- penicillin (1)
- penicillinase (1)
- photoelectrochemistry (1)
- plant virus detection (1)
- polyaniline (1)
- rehabilitation (1)
- running (1)
- sarcomere operating length (1)
- sensors (1)
- series elastic element behavior (1)
- shotgun sequencing (1)
- shoulder (1)
- sprint start (1)
- standard error of measurement (1)
- sterility tests (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stretch reflex (1)
- test-retest reliability (1)
- titanium dioxide photoanode (1)
- tobacco mosaic virus (TMV) (1)
- ultrasonography (1)
- ultrasound imaging (1)
- unloading (1)
- validation methods (1)
- walking (1)
Contractile behavior of the gastrocnemius medialis muscle during running in simulated hypogravity
(2021)
Vigorous exercise countermeasures in microgravity can largely attenuate muscular degeneration, albeit the extent of applied loading is key for the extent of muscle wasting. Running on the International Space Station is usually performed with maximum loads of 70% body weight (0.7 g). However, it has not been investigated how the reduced musculoskeletal loading affects muscle and series elastic element dynamics, and thereby force and power generation. Therefore, this study examined the effects of running on the vertical treadmill facility, a ground-based analog, at simulated 0.7 g on gastrocnemius medialis contractile behavior. The results reveal that fascicle−series elastic element behavior differs between simulated hypogravity and 1 g running. Whilst shorter peak series elastic element lengths at simulated 0.7 g appear to be the result of lower muscular and gravitational forces acting on it, increased fascicle lengths and decreased velocities could not be anticipated, but may inform the development of optimized running training in hypogravity. However, whether the alterations in contractile behavior precipitate musculoskeletal degeneration warrants further study.
Plant viruses are major contributors to crop losses and induce high economic costs worldwide. For reliable, on-site and early detection of plant viral diseases, portable biosensors are of great interest. In this study, a field-effect SiO2-gate electrolyte-insulator-semiconductor (EIS) sensor was utilized for the label-free electrostatic detection of tobacco mosaic virus (TMV) particles as a model plant pathogen. The capacitive EIS sensor has been characterized regarding its TMV sensitivity by means of constant-capacitance method. The EIS sensor was able to detect biotinylated TMV particles from a solution with a TMV concentration as low as 0.025 nM. A good correlation between the registered EIS sensor signal and the density of adsorbed TMV particles assessed from scanning electron microscopy images of the SiO2-gate chip surface was observed. Additionally, the isoelectric point of the biotinylated TMV particles was determined via zeta potential measurements and the influence of ionic strength of the measurement solution on the TMV-modified EIS sensor signal has been studied.
Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.
Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect.
Conventional EEG devices cannot be used in everyday life and hence, past decade research has been focused on Ear-EEG for mobile, at-home monitoring for various applications ranging from emotion detection to sleep monitoring. As the area available for electrode contact in the ear is limited, the electrode size and location play a vital role for an Ear-EEG system. In this investigation, we present a quantitative study of ear-electrodes with two electrode sizes at different locations in a wet and dry configuration. Electrode impedance scales inversely with size and ranges from 450 kΩ to 1.29 MΩ for dry and from 22 kΩ to 42 kΩ for wet contact at 10 Hz. For any size, the location in the ear canal with the lowest impedance is ELE (Left Ear Superior), presumably due to increased contact pressure caused by the outer-ear anatomy. The results can be used to optimize signal pickup and SNR for specific applications. We demonstrate this by recording sleep spindles during sleep onset with high quality (5.27 μVrms).