Article
Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (1359)
- INB - Institut für Nano- und Biotechnologien (503)
- Fachbereich Chemie und Biotechnologie (473)
- Fachbereich Elektrotechnik und Informationstechnik (414)
- IfB - Institut für Bioengineering (410)
- Fachbereich Energietechnik (361)
- Fachbereich Luft- und Raumfahrttechnik (254)
- Fachbereich Maschinenbau und Mechatronik (151)
- Fachbereich Wirtschaftswissenschaften (116)
- Fachbereich Bauingenieurwesen (69)
Language
- English (3285) (remove)
Document Type
- Article (3285) (remove)
Keywords
- Einspielen <Werkstoff> (7)
- avalanche (5)
- Earthquake (4)
- FEM (4)
- Finite-Elemente-Methode (4)
- LAPS (4)
- additive manufacturing (4)
- biosensors (4)
- field-effect sensor (4)
- frequency mixing magnetic detection (4)
- CellDrum (3)
- Heparin (3)
- Label-free detection (3)
- capacitive field-effect sensor (3)
- hydrogen peroxide (3)
- impedance spectroscopy (3)
- magnetic nanoparticles (3)
- shakedown analysis (3)
- snow (3)
- sustainability (3)
- tobacco mosaic virus (TMV) (3)
- Acyl-amino acids (2)
- Aeroelasticity (2)
- Aminoacylase (2)
- Bacillaceae (2)
- Bacillus atrophaeus (2)
- Biotechnological application (2)
- Boundary integral equations (2)
- Brake set-up (2)
- Butanol (2)
- CFD (2)
- Capacitive field-effect sensor (2)
- Chemometrics (2)
- Conductive boundary condition (2)
- Drinfeld modules (2)
- Einspielanalyse (2)
- Empirical process (2)
- Fault detection (2)
- Field-effect sensor (2)
- Freight rail (2)
- Germany (2)
- Goodness-of-fit test (2)
- Hot S-parameter (2)
- IR spectroscopy (2)
- Independence test (2)
- Light-addressable potentiometric sensor (2)
- Lipopolysaccharide (2)
- MINLP (2)
- Methane (2)
- NMR spectroscopy (2)
- Obstacle avoidance (2)
- Paired sample (2)
- Parametric bootstrap (2)
- Path planning (2)
- Principal component analysis (2)
- Pump System (2)
- Raman spectroscopy (2)
- SLM (2)
- Shakedown analysis (2)
- Simulation (2)
- Standardization (2)
- Stiffness (2)
- Subtilases (2)
- Subtilisin (2)
- Traglastanalyse (2)
- Transcendence (2)
- Transmission eigenvalues (2)
- UAV (2)
- bacterial cellulose (2)
- bubble column (2)
- capacitive field-effect sensors (2)
- carbonized rice husk (2)
- constructive alignment (2)
- damage (2)
- energy efficiency (2)
- examination (2)
- factory planning (2)
- fused filament fabrication (2)
- gold nanoparticles (2)
- harmonic radar (2)
- humans (2)
- immobilization (2)
- light-addressable potentiometric sensor (2)
- likelihood ratio test (2)
- limit analysis (2)
- locomotion (2)
- long-term retention (2)
- manufacturing flexibility (2)
- methanation (2)
- microfluidics (2)
- multimodal (2)
- muscle fascicle behavior (2)
- not identically distributed (2)
- penicillinase (2)
- plug flow reactor (2)
- practical learning (2)
- prebiotic (2)
- qNMR (2)
- rapid tooling (2)
- rebound-effect (2)
- shakedown (2)
- t-modules (2)
- ultrasound (2)
- ultrasound imaging (2)
- (Bio)degradation (1)
- (Poly)saccharides (1)
- 197m/gHg (1)
- 1P hub loads (1)
- 3-D printing (1)
- 316L (1)
- 3D nonlinear finite element model (1)
- 802.15.4 (1)
- ABE (1)
- Acceleration (1)
- Achilles tendon (1)
- Acid crash (1)
- Active humidity control (1)
- Actors (1)
- Actuator disk modelling (1)
- Acylation (1)
- Adaptive control (1)
- Additive Manufacturing (1)
- Additive manufacturing (1)
- Afterload (1)
- Ageing (1)
- Air purification (1)
- Aircraft sizing (1)
- Algal Turf Scrubber (1)
- Algal–bacterial bioflm (1)
- Alginate beads (1)
- Alkalihalobacillus okhensis (1)
- Aloe vera (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Analytischer Zulaessigkeitsnachweis (1)
- Anammox (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Antarctic Glaciology (1)
- Antibias (1)
- Architectural design (1)
- Architectural gear ratio (1)
- Artificial intelligence (1)
- Assembly (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Authenticity (1)
- Autolysis (1)
- Automated driving (1)
- Automatic control (1)
- Automotive application (1)
- Automotive safety approach (1)
- Autonomy (1)
- Avalanche (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- BET (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Balance (1)
- Balanced hypergraph (1)
- Bank-issued Warrants (1)
- Basis Reduktion (1)
- Basis reduction (1)
- Bauingenieurwesen (1)
- Behaviour factor q (1)
- Benchmark (1)
- Bicharakteristikenverfahren (1)
- Bio-inspired systems (1)
- Bioabsorbable (1)
- Biocatalysis (1)
- Biocomposites (1)
- Biofuel (1)
- Biogas (1)
- Biological hydrogen (1)
- Biomass (1)
- Biomechanical simulation (1)
- Bioreaktor (1)
- Biorefinery (1)
- Biosolubilization (1)
- Biosurfactants (1)
- Blade element method (1)
- Bloom’s Taxonomy (1)
- Bluetooth (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Booster Station (1)
- Booster Stations (1)
- Bootstrap (1)
- Bootstrapping (1)
- Borehole heat exchanger (1)
- Boundary integral equations, (1)
- Bragg peak (1)
- Brake test (1)
- Braking curves (1)
- Brands (1)
- Broad pH spectrum (1)
- Brownian Pillow (1)
- Buffering Capacity (1)
- C. acetobutylicum (1)
- CAD (1)
- CAV (1)
- CFD propeller simulation (1)
- CNOT (1)
- CO2 emission reduction targets (1)
- CRISPR/Cas9 (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Cardiovascular MRI (1)
- Cardiovascular Magnetic Resonance (1)
- Carrier solvents (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Censored data (1)
- Centrifugal twisting moment (1)
- Chance Constraint (1)
- Change (1)
- Chaperone (1)
- Chaperone co-expression (1)
- Charging station (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Chondroitin sulfate (1)
- Circuit simulation (1)
- Circular Dichroism (1)
- Circular bioeconomy (1)
- Civil engineering (1)
- Clinical decision support systems (1)
- Clostridium acetobutylicum (1)
- Clusterion (1)
- Co-managed care (1)
- Coal (1)
- Collective risk model (1)
- Commercial Vehicle (1)
- Common Rail Injection System (1)
- Competence Developing Games (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conditions (1)
- Conductive Boundary Condition (1)
- Consensus (1)
- Conservation laws (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Convex optimization (1)
- Cost function (1)
- Cost-effectiveness (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Crashworthiness (1)
- Cross border adjustment mechanism (1)
- Crude heparin (1)
- Crámer–von-Mises distance (1)
- Culture media (1)
- Cyclotron production (1)
- C–V method (1)
- DAC (1)
- DLR-ESTEC GOSSAMER roadmap for solar sailing (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Dark fermentation (1)
- Data-driven models (1)
- Decomposition (1)
- Decoupling (1)
- Deformation (1)
- Dehydrogenase (1)
- Design process (1)
- Design-by-analysis (1)
- Detergent protease (1)
- Deuterated solvents (1)
- Deuterium NMR (1)
- Diaphorase (1)
- Diesel Engine (1)
- Dietary supplements (1)
- Dimensional splitting (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discourse ethics (1)
- Discrete Optimization (1)
- Disposition Effect (1)
- Distributed Control Systems, (1)
- Diversity Management (1)
- Drag estimation (1)
- Driver assistance system (1)
- Driving cycle recognition (1)
- Druckbeanspruchung (1)
- Druckbehälter (1)
- Druckbelastung (1)
- Druckgeräte (1)
- Drug simulation (1)
- Dry-low-NOx (DLN) combustion (1)
- Duality (1)
- Dynamic simulation (1)
- E-Mobility (1)
- E. coli detection (1)
- ECMS (1)
- EGG (1)
- EIS capacitive sensor (1)
- ELISA (1)
- ES-FEM (1)
- Effective modal mass (1)
- Eigenvalue trajectories (1)
- Einspiel-Analyse (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastizität (1)
- Elderly (1)
- Electrochemical impedance spectroscopy (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Electronic cigarettes (1)
- Electronic vehicle (1)
- Elemental (1)
- Emilia-Romagna earthquake (1)
- Empirical consequence curves (1)
- Empirical fragility functions (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Energy management strategies (1)
- Energy-intensive industry (1)
- Engineering Application (1)
- Engineering Habitus (1)
- Enterprise information systems (1)
- Entropy solution (1)
- Environmental impact (1)
- Enzymatic biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme-linked immunosorbent assay (1)
- Epithel (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- European Transient Cycle (1)
- Eutectic Silver Copper alloy (1)
- Experiment (1)
- Experimental validation (1)
- Explainability (1)
- Exponential Euler scheme, (1)
- Exponential time differencing (1)
- Extension–twist coupling (1)
- External knee adduction moments (1)
- Extracellular enzymes (1)
- Extraterrestrial Glaciology (1)
- FS-FEM (1)
- Fall prevention (1)
- Fault approximation (1)
- Feature selection (1)
- Fehlerstellen (1)
- Fibroblast (1)
- Field effect (1)
- Field-effect biosensor (1)
- Finite difference methods (1)
- Finite differences (1)
- Finite element analysis (1)
- Finite element method (1)
- Finite element modelling (1)
- Finland (1)
- Fließgrenze (1)
- Floor prices (1)
- Flutter (1)
- Force (1)
- Forces (1)
- Fracture classification (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Frame structure (1)
- Free-base nicotine (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Fuel cell (1)
- Full-vehicle crash test (1)
- Functional Delta Method (1)
- Furnace (1)
- Fusion (1)
- GOSSAMER-1 (1)
- Ga-68 (1)
- Game-based learning (1)
- Gamification (1)
- Gamma distribution (1)
- Genetic algorithm (1)
- Geriatric (1)
- German (1)
- Glaciological instruments and methods (1)
- Glaucoma (1)
- Global and local collapse (1)
- Glucosamine (1)
- Gold nanoparticle (AuNP) (1)
- Gold nanoparticles (1)
- Goodness-of-fit tests for uniformity (1)
- Grenzwertberechnung (1)
- Ground-level falls (1)
- H2 (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Hall’s Theorem (1)
- Halotolerant protease (1)
- Handbike (1)
- Harnleiter (1)
- Hazard assessment (1)
- Health management system (1)
- Heart tissue culture (1)
- Heat transport (1)
- Helmholtz equation (1)
- Hemoglobin structure (1)
- Heterostructure (1)
- High field MRI (1)
- High hydrogen combustion (1)
- High-field NMR (1)
- Higher derivations (1)
- Higher-order codes (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Human Development Index (1)
- Human factors (1)
- Human-Computer interaction (1)
- Hydrogen combustion (1)
- Hydrogen gas turbine (1)
- Hydrogen peroxide (1)
- Hydrogenotrophic methanogens (1)
- Hydrolysis (1)
- Hyperdifferentials (1)
- Hypergraph (1)
- Hypersecretion (1)
- Hämoglobin (1)
- Hämoglobinstruktur (1)
- INSYSME (1)
- IP-based networks (1)
- IR (1)
- IT security education (1)
- Illustration (1)
- Image Quality Assessment (1)
- Image Quality Score (1)
- Image Reconstruction (1)
- Imaging (1)
- Impedance analysis (1)
- Impedance spectroscopy (1)
- Implicit methods (1)
- In-plane performance, isolation (1)
- Incident analysis (1)
- Inclusion bodies (1)
- Incomplete data (1)
- Individual Investors (1)
- Induced pluripotent stem cells (1)
- Industrial Automation Technology, (1)
- Infill wall design (1)
- Information extraction (1)
- Inorganic ions (1)
- Inotropic compounds (1)
- Instructional design (1)
- Integrated empirical distribution (survival) function (1)
- Interior Neumann eigenvalues (1)
- Interior transmission eigenvalues (1)
- Interior transmission problem (1)
- Interstellar objects (1)
- Interval Time Series (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering (1)
- Inverse scattering problem (1)
- Inverse spectral problem (1)
- Ion channels (1)
- Ions (1)
- Iterative learning control (1)
- Justice (1)
- Keyword analysis (1)
- Kinetic energy (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Koenig’s Theorem (1)
- Kohlenstofffaser (1)
- LPBF (1)
- LPS (1)
- Lab-on-Chip (1)
- Lactobacillus rhamnosus GG (1)
- Landslide tsunamis (1)
- Langevin theory (1)
- Large scale tests (1)
- Larynx position (1)
- Latvia (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Left ventriular function (1)
- Level system (1)
- Li7La3Zr2O12 (1)
- LiGaO2 (1)
- Lidar (1)
- Lifting propeller (1)
- Light-addressable Potentiometric Sensor (1)
- Lignocellulose (1)
- Limit analysis (1)
- Linear discriminant analysis (1)
- Linear elastic analysis (1)
- Liver (1)
- Local path planning (1)
- Long COVID (1)
- Low field NMR (1)
- Low-field NMR (1)
- Luftreiniger (1)
- Luxury (1)
- MCDA (1)
- MILP (1)
- MOS (1)
- MR safety (1)
- MR-stethoscope (1)
- MRI (1)
- MST (1)
- MUT measurement; scanner (1)
- Machine learning (1)
- Magnetic field strength (1)
- Magnetic nanoparticles (1)
- Magnetic resonance imaging (MRI) (1)
- Magneto alert sensor (1)
- Mainstream (1)
- Manifestations (1)
- Manipulated variables (1)
- Manufacturer (1)
- Marginal homogeneity test (1)
- Marker-free mutagenesis (1)
- Masonry infill (1)
- Masonry partition walls (1)
- Master stamp (1)
- Matching (1)
- Materialermüdung (1)
- Matrix exponential (1)
- Measurement models (1)
- Measurement uncertainty (1)
- Mechanotransduction (1)
- Medical AI (1)
- Medical radionuclide production (1)
- Medusomyces gisevi (1)
- Meitner-Auger-electron (MAE) (1)
- Metabolic shift (1)
- Metal contaminants (1)
- Metascintillator (1)
- Methanogenesis (1)
- Microcirculation (1)
- Microfluidic solvent extraction (1)
- Micromagnetic simulation (1)
- Micromix combustion (1)
- Mikrosystemtechnik (1)
- Mild cognitive impairment (1)
- Missions (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Mode converter (1)
- Model-driven software engineering (1)
- Modelica (1)
- Modeling (1)
- Modelling (1)
- Modern constructions (1)
- Molecular modelling (1)
- Molecular weight determination (1)
- Molten salt receiver system (1)
- Molten salt solar tower (1)
- Monotone methods (1)
- Monte Carlo Tree Search (1)
- Morphing (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional partial differential equations (1)
- Multi-objective optimization (1)
- Multi-sample problem (1)
- Multi-storey (1)
- Multianalyte detection (1)
- Multicell (1)
- Multiple TOF kernels (1)
- Multiplexing (1)
- Multirotor UAS (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NGN (1)
- NMR (1)
- NMR exchange relaxometry (1)
- NONOate (1)
- Natural fibres (1)
- Natural frequency (1)
- Negative Feedback Trading (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Nitrogen removal (1)
- Non-model-based Evaluation (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nonlinear PDEs (1)
- Nonlinear eigenvalue problems (1)
- Normative standards (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- Numerical modelling (1)
- Numerics (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Online diagnostic (1)
- Operations (1)
- Organic acids (1)
- Organic light-emitting diode display (1)
- Organic waste (1)
- Organizational Culture (1)
- Organkultur (1)
- Osteoporose (1)
- Osteoporosis (1)
- Out-of-plane capacity (1)
- Overland flow (1)
- P2G (1)
- PBEE (1)
- PEM fuel cell (1)
- PIV (1)
- PLS-regression (1)
- PROFINET (1)
- Parabolic SPDEs (1)
- Paralympic sport (1)
- Parasitic drag (1)
- Parking (1)
- Partial nitritation (1)
- Penicillin (1)
- Periods (1)
- Permeability (1)
- Permeabilität (1)
- Peroxidase (1)
- Pflanzenphysiologie (1)
- Pflanzenscanner (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Photolithographic mimics (1)
- Physiology (1)
- Piping (1)
- Planning process (1)
- Plant virus (1)
- Plasma (1)
- Plasma diagnostics (1)
- Plasmacluster ion technology (1)
- Plastizität (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Polymer-matrix composites (1)
- Polysaccharides (1)
- Porositat (1)
- Post-COVID-19 syndrome (1)
- Potential theory (1)
- Powertrain (1)
- Pre-culture (1)
- Precast buildings (1)
- Prediction of molecular features (1)
- Predictive battery discharge (1)
- Preference assessment (1)
- Pressure loaded crack-face (1)
- Pretreatment (1)
- Prevention (1)
- Probability distribution mapping (1)
- Process virtualization (1)
- Product bundling (1)
- Product-integration (1)
- Progressive plastic deformation (1)
- Propeller (1)
- Propeller aerodynamics (1)
- Propeller elasticity (1)
- Propeller performance (1)
- Propeller whirl flutter (1)
- Proper Orthogonal Decomposition (1)
- Prophylaxis (1)
- Protein structure complexity (1)
- Proximal humerus fracture (1)
- Pulsations (1)
- Pumping systems (1)
- Q-criterion (1)
- Quality control (1)
- Quantitative structure activity relationship (1)
- Quantum chemistry (1)
- Quartz crystal microbalance (1)
- RAMMS (1)
- RVA (1)
- Radar (1)
- Rapid Prototyping (1)
- Rapid Technologie (1)
- Rapid prototyping (1)
- Ratchetting (1)
- Raumluft (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Red blood cell storage (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Reinforced concrete frame (1)
- Relative air humidity (1)
- Requirements prioritization (1)
- Requirements relations (1)
- Resampling test (1)
- Reservation system (1)
- Resistive temperature detector (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Response Surface Method (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Robotic rehabilitation (1)
- Rohr (1)
- Rohrbruch (1)
- Rotary encoder (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- SFCW (1)
- SOA (1)
- SSE) JEL : O33 (1)
- ScaLAPACK (1)
- Scalar parameters (1)
- Schwammknochen (1)
- Seismic design (1)
- Seismic loading (1)
- Selective Catalytic Reduction (1)
- Selective Laser Melting (SLM) (1)
- Self-driving (1)
- Semi-parametric random censorship model (1)
- Septic cardiomyopathy (1)
- Services (1)
- Shakedown (1)
- Shakedown criterion (1)
- Shape and surface properties (1)
- Shoulder (1)
- Shunting (1)
- Silk fibroin (1)
- Simultaneous determination (1)
- Skeletal muscle (1)
- Slab deflection (1)
- Small Aral Sea (1)
- Small spacecraft (1)
- Snow (1)
- Sn₃O₄ (1)
- Soft independent modeling of class analogy (1)
- Software and systems modeling (1)
- Solar sail (1)
- Solitary waves (1)
- Sound Pressure Level (1)
- Source term (1)
- Spectroscopy (1)
- Spleen (1)
- Stahl (1)
- Steel industry (1)
- Stenotrophomonas maltophilia (1)
- Sterilisation process (1)
- Stochastic Programming (1)
- Streptomyces griseus (1)
- Streptomyces lividans (1)
- Stress concentrations (1)
- Structural design (1)
- Structure and Stages (1)
- Strukturanalyse (1)
- Subclacial exploration (1)
- Subglacial lakes (1)
- Surface imprinted polymer (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Suspension bridge (1)
- TMV adsorption (1)
- TOF PET (1)
- Tank (1)
- Targeted radionuclide therapy (TRT) (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (1)
- Technical Operations Research (TOR) (1)
- Telecommunication (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Thermal conductivity (1)
- Thin shell finite elements (1)
- Tinetti test (1)
- Tissue Engineering (1)
- Tobacco mosaic virus (TMV) (1)
- Tomography (1)
- Tool support (1)
- Tools (1)
- Trading Behavior (1)
- Traglast (1)
- Train composition (1)
- Trajectories (1)
- Transfer impedance (1)
- Transformation (1)
- Transient flux distribution (1)
- Transmission Eigenvalues (1)
- Trapeze effect (1)
- Two-phase modelling (1)
- Typographie (1)
- USP (1)
- Uktrahigh field MRI (1)
- Ultrasound (1)
- Uncertainty (1)
- Uniaxial compression test (1)
- Unmanned aerial vehicles (1)
- Unreinforced masonry buildings (1)
- Unsteady aerodynamics (1)
- Uracil-phosphoribosyltransferase (1)
- User study (1)
- Utilization improvement (1)
- VM (1)
- VOF (1)
- VOP compression (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Vertex cover (1)
- Vibrio natriegens (1)
- Virtual reality (1)
- Virtuelle Maschine (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Voice assessment (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Wastewater (1)
- Water Distribution (1)
- Water Supply Networks (1)
- Weak organic acids (1)
- Wiegand sensor (1)
- Wind milling (1)
- Wind tunnel experiments (1)
- Wireless Networks (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Wundheilung (1)
- XML (1)
- XOR (1)
- Zeta potential (1)
- Zug-Druck Belastung (1)
- access control (1)
- acetoin (1)
- acetoin reductase (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- actuator-sensor system (1)
- adaptive systems (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- alcoholic beverages (1)
- allocation (1)
- alternierend Verformbarkeit (1)
- aminooctanethiol (1)
- amperometric biosensors (1)
- anaesthetic complications (1)
- anammox (1)
- anisotropy (1)
- annealing (1)
- aortic perfusion (1)
- aquaculture (1)
- architectural design (1)
- architectural layered representation (1)
- aromatic amines (1)
- arresters (1)
- artificial intelligence (1)
- artificial olfactory image (1)
- aseptic parameters (1)
- aspergillus (1)
- assistance system (1)
- asymptotic relative efficiency (1)
- atmospheric modeling (1)
- atomic layer deposition (1)
- authorization (1)
- automated vehicles (1)
- automotive (1)
- autonomous navigation (1)
- availability (1)
- barium strontium titanate (1)
- batteries and fuel cells (1)
- bi-enzyme biosensor (1)
- biaxial tensile experiment (1)
- bicharacteristics (1)
- bio-methane (1)
- bioavailability (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biodegradable polymers (1)
- biofilms (1)
- biological dosimeter (1)
- biomechanics (1)
- biomethane (1)
- biopharmaceutical production process (1)
- biopotential electrodes (1)
- biosensor (1)
- body imaging at 7 T MRI (1)
- body imaging at UHF MRI (1)
- body limbs (1)
- bone density (1)
- bone structure (1)
- bootstrap (1)
- borefields (1)
- borehole disposal (1)
- brachytherapy (1)
- building energy modelling (1)
- building energy simulation (1)
- burst pressure (1)
- burst tests (1)
- business culture (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- cancellous bone (1)
- capacitive EIS sensor (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive model (1)
- carbon dioxide removal (1)
- carbon electrodes (1)
- cardiac gating (1)
- cardiomyocyte biomechanics (1)
- cardiovascular MR imaging (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- change (1)
- change management (1)
- chemical sensor (1)
- chip-based sensor setup (1)
- churches (1)
- civil engineering (1)
- climate change (1)
- climate neutrality (1)
- cobald chrome (1)
- coculture (1)
- cognitive impairment (1)
- coherent structures (1)
- colorization (1)
- community dwelling (1)
- complete block symmetry (1)
- compression behavior (1)
- computational fluid dynamics analysis (1)
- concentrating collector (1)
- concrete (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- conductors (1)
- confidence interval (1)
- connected automated vehicles (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- containers (1)
- control gate (1)
- corporate sustainability (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- critical (1)
- crop yield (1)
- crystallization (1)
- cyber-physical production systems (1)
- dam-break (1)
- debris flow (1)
- deficit irrigation (1)
- dental bridges (1)
- dental trauma (1)
- deserts (1)
- design of technical systems (1)
- detection of charged macromolecules (1)
- detergent protease (1)
- dialysis (1)
- difficult airway (1)
- digital factory (1)
- digital twin (1)
- direct air capture (1)
- direct method (1)
- disposal facility (1)
- distorted element (1)
- distribution grid simulation (1)
- distribution strategy (1)
- diversity management (1)
- double-lumen tube intubation (1)
- downstream processing design (1)
- drag force (1)
- drop jump (1)
- drug metabolising enzymes (1)
- drug–drug interactions (1)
- e-mobility (1)
- eVTOL development (1)
- eVTOL safety (1)
- earthquake engineering (1)
- ecological structure (1)
- economics (1)
- efficiency side-effects (1)
- eigensolvers (1)
- elastic scattering (1)
- elastic solids (1)
- elastomers (1)
- electrical conductivity of liquids (1)
- electrocardiogram (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electrolyte-insulator-semiconductor capacitors (1)
- electromyography (1)
- electronic nose (1)
- electrospinning (1)
- encapsulation materials (1)
- endoluminal (1)
- endospores (1)
- energy (1)
- energy absorption (1)
- energy dissipation (1)
- energy transfer (1)
- engineering (1)
- engines (1)
- entrepreneurship education (1)
- enzymatic (bio)degradation (1)
- enzymatic biosensor (1)
- enzyme cascade (1)
- enzyme kinetics (1)
- enzyme-logic gate (1)
- epithelization (1)
- equivalent circuit (1)
- equivalent stiffness (1)
- event-based simulation (1)
- exchangeability test (1)
- exopolysaccharides (1)
- experiment quality (1)
- experimental evaluation (1)
- extracorporeal membrane oxygenation (1)
- eye movement modelling examples (1)
- fatigue analyses (1)
- fatty acid (1)
- fibers (1)
- fibroin (1)
- field-effect structure (1)
- filamentous fungi (1)
- flaw (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- framework (1)
- frequency mixing (1)
- fuel cell vehicle (1)
- functional data (1)
- ga-doping (1)
- gait (1)
- gamification (1)
- garnet solid electrolyte (1)
- gas sensor (1)
- gaseous hydrogen peroxide (1)
- genetic algorithm (1)
- genome engineering (1)
- geological disposal (1)
- geothermal (1)
- global optimization (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- glycine (1)
- goodness-of-fit test (1)
- granular silo (1)
- graphene oxide (1)
- grey energy (1)
- grid computing (1)
- halotolerant protease (1)
- harmonic radar tags (1)
- healthy aging (1)
- heat demand (1)
- heat transfer coefficient (1)
- heating system (1)
- heavy metals (1)
- hiPS cardiomyocytes (1)
- high field MR imaging (1)
- high-alkaline subtilisin (1)
- high-intensity exercise (1)
- high-k material (1)
- history (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- human dermal fibroblasts (1)
- human metabolites (1)
- humic acid (1)
- hybrid model validation (1)
- hydraulic modelling (1)
- hydrogel (1)
- hydrogels (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- hypoplasticity (1)
- ignition (1)
- impulsive effects (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- incontinence (1)
- independence test (1)
- industrial agents (1)
- industry 4.0 (1)
- infill strategy (1)
- innovation management (1)
- integrated transmit coil arrays (1)
- intelligent control (1)
- intelligent energy management (1)
- intraclass correlation coefficient (1)
- irradiation (1)
- jevons paradox (1)
- key performance indicators (1)
- konvexe Optimierung (1)
- lable-free detection (1)
- large language models (1)
- large-scale inspection (1)
- layer-by-layer technique (1)
- legal obligations (1)
- libraries (1)
- light-addressable electrode (1)
- light-addressing technologies (1)
- lightning (1)
- lightning protection (1)
- lignite (1)
- limit load (1)
- lipopolysaccharide (1)
- lipopolysaccharides (1)
- liquid-storage tank (1)
- liquid-structure interaction (1)
- literature (1)
- lizards (1)
- load limit (1)
- low-rank coal (1)
- machine learning (1)
- macro-element (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic relaxation (1)
- magnetic resonance imaging (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic sensors (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- mainstream deammonification (1)
- management (1)
- manufacturing (1)
- manufacturing data model (1)
- marketing (1)
- mathematical optimization (1)
- mechanical buffer (1)
- mechanical properties (1)
- metagenomics (1)
- metal-oxide-semiconductor structure (1)
- metathesis (1)
- method of fundamental solutions (1)
- microbial diversity (1)
- micromagnetic simulation (1)
- micronutrients (1)
- microplasma (1)
- microwave (MW) plasma (1)
- microwave measurements (1)
- mix flexibility (1)
- mixed-integer linear programming (1)
- mobile manipulation (1)
- model performance (1)
- motivation (1)
- multi-agent systems (1)
- multi-functional material (1)
- multi-sensing platform (1)
- multianalyte detection (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multiplex detection (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- nanomaterials (1)
- nanoparticle coverage (1)
- nanostructured carbonized plant parts (1)
- nanostrukturierte carbonisierte Pflanzenteile (1)
- naphtols (1)
- negative emissions (1)
- neutrons (1)
- next generation network (1)
- nitrogen elimination (1)
- non-simplex S-FEM elements (1)
- nonlinear VNA measurements (1)
- nonlinear radar (1)
- nonlinear transient analyses (1)
- novel photoexcitation method (1)
- nuclear waste (1)
- numerical model (1)
- on-chip integrated addressable EISCAP sensors (1)
- onion (1)
- optical fibers (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- optimization (1)
- optimization system (1)
- organosilanes (1)
- overload (1)
- oxidative stable protease (1)
- pH sensors (1)
- parabolic flight (1)
- penicillin (1)
- performance analysis (1)
- performance testing (1)
- performativity in personal knowledge (1)
- personal way of designing (1)
- phenols (1)
- phonocardiogram (1)
- photoelectrochemistry (1)
- physical model (1)
- physiology (1)
- pipes (1)
- planning (1)
- plant scanner (1)
- plant stress (1)
- plant virus detection (1)
- plasma jet (1)
- plug-based microfluidic device (1)
- point-focussing system (1)
- poly(d, l-lactic acid) (1)
- polyamide (1)
- polyaniline (1)
- polyaspartic acid (1)
- polyester (1)
- polyetheretherketone (1)
- polyetheretherketone (PEEK) (1)
- polystyrene sulfonate (1)
- porous materials (1)
- portfolio risk (1)
- power generation (1)
- power transmission lines (1)
- power-to-gas (1)
- prevention (1)
- probability distribution (1)
- product bundling (1)
- product liability (1)
- production planning and control (1)
- programming (1)
- prostate cancer (1)
- prostatectomy (1)
- proton therapy (1)
- protons (1)
- provenance (1)
- psychosocial (1)
- pullulan (1)
- quality of life (1)
- random effects (1)
- random effects meta-regression model (1)
- ratchetting (1)
- raytracing (1)
- recombinant expression (1)
- rehabilitation (1)
- relative dosimetry (1)
- reliability analysis (1)
- reliability of structures (1)
- remote sensing (1)
- renewable resources (1)
- research association (1)
- resilience (1)
- resource abundance (1)
- resource management (1)
- retention time (1)
- retinal microvasculature (1)
- retinal vessels (1)
- review (1)
- rollout (1)
- rubber (1)
- running (1)
- sEMG (1)
- sarcomere operating length (1)
- scan strategy (1)
- scanned light pulse technique (1)
- scheduling (1)
- security (1)
- seismic response (1)
- semantic role labeling (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- service-oriented architectures (1)
- shakedown analyses (1)
- shotgun sequencing (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- sizing (1)
- slum classification (1)
- smart-charging (1)
- smooth muscle contraction (1)
- socio-economic welfare (1)
- soil amendment (1)
- soil health (1)
- soil remediation (1)
- solar process heat (1)
- solid-state battery (1)
- spatial resolution (1)
- speaker attribution (1)
- spore kill rate (1)
- sprint start (1)
- standard error of measurement (1)
- standards (1)
- sterilisation (1)
- sterility (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stiffness (1)
- stochastic optimization (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- structure-soil-structure interaction (1)
- superabsorbent polymers (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- supramolecular structures (1)
- surface functionalization (1)
- surface modification (1)
- surface-orthogonal path planning (1)
- surges (1)
- survival (1)
- swelling properties (1)
- swimming (1)
- synchronization (1)
- system optimization (1)
- system synthesis (1)
- systematic (1)
- technical operations research (1)
- technology planning (1)
- telecommunication (1)
- temperature (1)
- tendon rupture (1)
- tension–torsion loading (1)
- test-retest reliability (1)
- theory and modeling (1)
- thermal dose (1)
- thermal ratcheting (1)
- thermometry (1)
- tilted constant illumination (1)
- tissue temperature (1)
- titanium dioxide photoanode (1)
- transmit antenna arrays (1)
- transponder (1)
- transporters (1)
- tri-lineage differentiation (1)
- truss (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- ultrathin gate insulators (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- urease (1)
- validation methods (1)
- vault (1)
- vessels (1)
- video learning (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual clean room (1)
- viscoelasticity (1)
- visualization (1)
- volume flexibility (1)
- walking (1)
- walking gait (1)
- wastewater (1)
- water economy (1)
- water supply design (1)
- wind turbine production (1)
- workflow (1)
- workflow management software (1)
- wound healing (1)
- yield (1)
- yield stress (1)
- α-aminoacylase (1)
- ε-lysine acylase (1)
Purpose
In the determination of the measurement uncertainty, the GUM procedure requires the building of a measurement model that establishes a functional relationship between the measurand and all influencing quantities. Since the effort of modelling as well as quantifying the measurement uncertainties depend on the number of influencing quantities considered, the aim of this study is to determine relevant influencing quantities and to remove irrelevant ones from the dataset.
Design/methodology/approach
In this work, it was investigated whether the effort of modelling for the determination of measurement uncertainty can be reduced by the use of feature selection (FS) methods. For this purpose, 9 different FS methods were tested on 16 artificial test datasets, whose properties (number of data points, number of features, complexity, features with low influence and redundant features) were varied via a design of experiments.
Findings
Based on a success metric, the stability, universality and complexity of the method, two FS methods could be identified that reliably identify relevant and irrelevant influencing quantities for a measurement model.
Originality/value
For the first time, FS methods were applied to datasets with properties of classical measurement processes. The simulation-based results serve as a basis for further research in the field of FS for measurement models. The identified algorithms will be applied to real measurement processes in the future.
The European Union's aim to become climate neutral by 2050 necessitates ambitious efforts to reduce carbon emissions. Large reductions can be attained particularly in energy intensive sectors like iron and steel. In order to prevent the relocation of such industries outside the EU in the course of tightening environmental regulations, the establishment of a climate club jointly with other large emitters and alternatively the unilateral implementation of an international cross-border carbon tax mechanism are proposed. This article focuses on the latter option choosing the steel sector as an example. In particular, we investigate the financial conditions under which a European cross border mechanism is capable to protect hydrogen-based steel production routes employed in Europe against more polluting competition from abroad. By using a floor price model, we assess the competitiveness of different steel production routes in selected countries. We evaluate the climate friendliness of steel production on the basis of specific GHG emissions. In addition, we utilize an input-output price model. It enables us to assess impacts of rising cost of steel production on commodities using steel as intermediates. Our results raise concerns that a cross-border tax mechanism will not suffice to bring about competitiveness of hydrogen-based steel production in Europe because the cost tends to remain higher than the cost of steel production in e.g. China. Steel is a classic example for a good used mainly as intermediate for other products. Therefore, a cross-border tax mechanism for steel will increase the price of products produced in the EU that require steel as an input. This can in turn adversely affect competitiveness of these sectors. Hence, the effects of higher steel costs on European exports should be borne in mind and could require the cross-border adjustment mechanism to also subsidize exports.
The potential of electronic markets in enabling innovative product bundles through flexible and sustainable partnerships is not yet fully exploited in the telecommunication industry. One reason is that bundling requires seamless de-assembling and re-assembling of business processes, whilst processes in telecommunication companies are often product-dependent and hard to virtualize. We propose a framework for the planning of the virtualization of processes, intended to assist the decision maker in prioritizing the processes to be virtualized: (a) we transfer the virtualization pre-requisites stated by the Process Virtualization Theory in the context of customer-oriented processes in the telecommunication industry and assess their importance in this context, (b) we derive IT-oriented requirements for the removal of virtualization barriers and highlight their demand on changes at different levels of the organization. We present a first evaluation of our approach in a case study and report on lessons learned and further steps to be performed.
As the potential of a next generation network (NGN) is recognised, telecommunication companies consider switching to it. Although the implementation of an NGN seems to be merely a modification of the network infrastructure, it may trigger or require changes in the whole company, because it builds upon the separation between service and transport, a flexible bundling of services to products and the streamlining of the IT infrastructure. We propose a holistic framework, structured into the layers ‘strategy’, ‘processes’ and ‘information systems’ and incorporate into each layer all concepts necessary for the implementation of an NGN, as well as the alignment of these concepts. As a first proof-of-concept for our framework we have performed a case study on the introduction of NGN in a large telecommunication company; we show that our framework captures all topics that are affected by an NGN implementation.
The molecular weight properties of lignins are one of the key elements that need to be analyzed for a successful industrial application of these promising biopolymers. In this study, the use of 1H NMR as well as diffusion-ordered spectroscopy (DOSY NMR), combined with multivariate regression methods, was investigated for the determination of the molecular weight (Mw and Mn) and the polydispersity of organosolv lignins (n = 53, Miscanthus x giganteus, Paulownia tomentosa, and Silphium perfoliatum). The suitability of the models was demonstrated by cross validation (CV) as well as by an independent validation set of samples from different biomass origins (beech wood and wheat straw). CV errors of ca. 7–9 and 14–16% were achieved for all parameters with the models from the 1H NMR spectra and the DOSY NMR data, respectively. The prediction errors for the validation samples were in a similar range for the partial least squares model from the 1H NMR data and for a multiple linear regression using the DOSY NMR data. The results indicate the usefulness of NMR measurements combined with multivariate regression methods as a potential alternative to more time-consuming methods such as gel permeation chromatography.
In this study, a recently proposed NMR standardization approach by 2H integral of deuterated solvent for quantitative multicomponent analysis of complex mixtures is presented. As a proof of principle, the existing NMR routine for the analysis of Aloe vera products was modified. Instead of using absolute integrals of targeted compounds and internal standard (nicotinamide) from 1H-NMR spectra, quantification was performed based on the ratio of a particular 1H-NMR compound integral and 2H-NMR signal of deuterated solvent D2O. Validation characteristics (linearity, repeatability, accuracy) were evaluated and the results showed that the method has the same precision as internal standardization in case of multicomponent screening. Moreover, a dehydration process by freeze drying is not necessary for the new routine. Now, our NMR profiling of A. vera products needs only limited sample preparation and data processing. The new standardization methodology provides an appealing alternative for multicomponent NMR screening. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and is recommended in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).
The investigation of the possibility to determine various characteristics of powder heparin (n = 115) was carried out with infrared spectroscopy. The evaluation of heparin samples included several parameters such as purity grade, distributing company, animal source as well as heparin species (i.e. Na-heparin, Ca-heparin, and heparinoids). Multivariate analysis using principal component analysis (PCA), soft independent modelling of class analogy (SIMCA), and partial least squares – discriminant analysis (PLS-DA) were applied for the modelling of spectral data. Different pre-processing methods were applied to IR spectral data; multiplicative scatter correction (MSC) was chosen as the most relevant.
Obtained results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. Good predictive ability of this approach demonstrates the potential of IR spectroscopy and chemometrics for screening of heparin quality. This approach, however, is designed as a screening tool and is not considered as a replacement for either of the methods required by USP and FDA.
Quantitative nuclear magnetic resonance (qNMR) is routinely performed by the internal or external standardization. The manuscript describes a simple alternative to these common workflows by using NMR signal of another active nuclei of calibration compound. For example, for any arbitrary compound quantification by NMR can be based on the use of an indirect concentration referencing that relies on a solvent having both 1H and 2H signals. To perform high-quality quantification, the deuteration level of the utilized deuterated solvent has to be estimated.
In this contribution the new method was applied to the determination of deuteration levels in different deuterated solvents (MeOD, ACN, CDCl3, acetone, benzene, DMSO-d6). Isopropanol-d6, which contains a defined number of deuterons and protons, was used for standardization. Validation characteristics (precision, accuracy, robustness) were calculated and the results showed that the method can be used in routine practice. Uncertainty budget was also evaluated. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and can be applied in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).
Heparin is a natural polysaccharide, which plays essential role in many biological processes. Alterations in building blocks can modify biological roles of commercial heparin products, due to significant changes in the conformation of the polymer chain. The variability structure of heparin leads to difficulty in quality control using different analytical methods, including infrared (IR) spectroscopy. In this paper molecular modelling of heparin disaccharide subunits was performed using quantum chemistry. The structural and spectral parameters of these disaccharides have been calculated using RHF/6-311G. In addition, over-sulphated chondroitin sulphate disaccharide was studied as one of the most widespread contaminants of heparin. Calculated IR spectra were analyzed with respect to specific structure parameters. IR spectroscopic fingerprint was found to be sensitive to substitution pattern of disaccharide subunits. Vibrational assignments of calculated spectra were correlated with experimental IR spectral bands of native heparin. Chemometrics was used to perform multivariate analysis of simulated spectral data.
Lignin is a promising renewable biopolymer being investigated worldwide as an environmentally benign substitute of fossil-based aromatic compounds, e.g. for the use as an excipient with antioxidant and antimicrobial properties in drug delivery or even as active compound. For its successful implementation into process streams, a quick, easy, and reliable method is needed for its molecular weight determination. Here we present a method using 1H spectra of benchtop as well as conventional NMR systems in combination with multivariate data analysis, to determine lignin’s molecular weight (Mw and Mn) and polydispersity index (PDI). A set of 36 organosolv lignin samples (from Miscanthus x giganteus, Paulownia tomentosa and Silphium perfoliatum) was used for the calibration and cross validation, and 17 samples were used as external validation set. Validation errors between 5.6% and 12.9% were achieved for all parameters on all NMR devices (43, 60, 500 and 600 MHz). Surprisingly, no significant difference in the performance of the benchtop and high-field devices was found. This facilitates the application of this method for determining lignin’s molecular weight in an industrial environment because of the low maintenance expenditure, small footprint, ruggedness, and low cost of permanent magnet benchtop NMR systems.