Refine
Year of publication
- 2019 (198) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (65)
- IfB - Institut für Bioengineering (41)
- Fachbereich Luft- und Raumfahrttechnik (38)
- Fachbereich Elektrotechnik und Informationstechnik (30)
- INB - Institut für Nano- und Biotechnologien (20)
- Fachbereich Energietechnik (19)
- Fachbereich Maschinenbau und Mechatronik (17)
- Fachbereich Chemie und Biotechnologie (11)
- Fachbereich Bauingenieurwesen (8)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (8)
Language
- English (198) (remove)
Document Type
- Article (97)
- Conference Proceeding (76)
- Part of a Book (15)
- Book (4)
- Doctoral Thesis (3)
- Conference: Meeting Abstract (2)
- Talk (1)
Keywords
- Enterprise Architecture (2)
- Seismic design (2)
- Achilles tendon (1)
- Advanced driver assistance systems (ADAS/AD) (1)
- Aircraft design (1)
- Analytics (1)
- Architectural gear ratio (1)
- Assistive technology (1)
- Automatic control (1)
- BEV (1)
- Case Study (1)
- Change Management (1)
- Combustion (1)
- Components (1)
- Corporate Culture (1)
- Correlations (1)
- Decentral (1)
- Design examples (1)
- Design rules (1)
- Digital Age (1)
- Diversity Management (1)
- Drag (1)
- Earthquake (1)
- Emilia-Romagna earthquake (1)
- Empirical consequence curves (1)
- Empirical fragility functions (1)
- Engineering (1)
- Engineering optimization (1)
- Eurocode 8 (1)
- Force (1)
- Gearbox (1)
- Geometry (1)
- Goodness-of-fit test (1)
- Graph Theory (1)
- Green aircraft (1)
- Gust wind response (1)
- Human-Computer interaction (1)
- Hybrid-electric aircraft (1)
- Hydrogen (1)
- ISO 26262 (1)
- In-plane (1)
- Industrial units (1)
- Innovation Management (1)
- Isolation (1)
- Iterative learning control (1)
- Knee (1)
- Load modeling (1)
- Low NOx (1)
- Low emission (1)
- Machine learning (1)
- Mechanical (1)
- Mixed-integer nonlinear black-box optimization (1)
- Multi-sample problem (1)
- On-site (1)
- Optimization (1)
- Out-of-plane (1)
- PBEE (1)
- Parametric bootstrap (1)
- Powertrain (1)
- Pre-treatment (1)
- Precast buildings (1)
- Preface (1)
- Product family optimization (1)
- Pushover analysis (1)
- Rehabilitation engineering (1)
- Resilience Assessment (1)
- Response spectrum (1)
- Robotic Process Automation (1)
- Running (1)
- Safety of the intended functionality (SOTIF) (1)
- Safety-critical systems validation (1)
- Seismic (1)
- Silos (1)
- Software Robots (1)
- Spectral analysis (1)
- Statistics (1)
- Stiffness (1)
- Tanks (1)
- Tendon properties (1)
- Training (1)
- Unmanned Air Vehicle (1)
- Volume of confidence regions (1)
- WLTP (1)
- Water Supply System (1)
- Wind turbulence (1)
- asymptotic relative efficiency (1)
- batch reproducibility (1)
- concentrating collector (1)
- environmental correlation (1)
- fluorescent protein carrier (1)
- frequency mixing magnetic detection (1)
- greenhouse cultivation (1)
- likelihood ratio test (1)
- magnetic actuation (1)
- magnetic sandwich immunoassay (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- plant molecular farming (1)
- point-focussing system (1)
- raytracing (1)
- responsive space (1)
- small solar system body characterisation (1)
- small spacecraft asteroid lander (1)
- small spacecraft solar sail (1)
- solar process heat (1)
- superparamagnetic bead (1)
- system engineering (1)
Bacterial cell appendix formation supports cell-cell interaction, cell adhesion and cell movement. Additionally, in bioelectrochemical systems (BES), cell appendages have been shown to participate in extracellular electron transfer. In this work, the cell appendix formation of Clostridium acetobutylicum in biofilms of a BES are imaged and compared with conventional biofilms. Under all observed conditions, the cells possess filamentous appendages with a higher number and density in the BES. Differences in the amount of extracellular polymeric substance in the biofilms of the electrodes lead to the conclusion that the cathode can be used as electron donor and the anode as electron acceptor by C. acetobutylicum. When using conductive atomic force microscopy, a current response of about 15 nA is found for the cell appendages from the BES. This is the first report of conductivity for clostridial cell appendices and represents the basis for further studies on their role for biofilm formation and electron transfer.
Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular “toolbox” as a new example of Boolean logic gates based on enzyme reactions.
Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.