Article
Refine
Year of publication
Institute
- INB - Institut für Nano- und Biotechnologien (503) (remove)
Language
- English (503) (remove)
Document Type
- Article (503) (remove)
Keywords
- biosensors (4)
- frequency mixing magnetic detection (4)
- LAPS (3)
- Label-free detection (3)
- capacitive field-effect sensor (3)
- field-effect sensor (3)
- magnetic nanoparticles (3)
- tobacco mosaic virus (TMV) (3)
- Acyl-amino acids (2)
- Aminoacylase (2)
- Bacillaceae (2)
- Bacillus atrophaeus (2)
- Biotechnological application (2)
- Capacitive field-effect sensor (2)
- Light-addressable potentiometric sensor (2)
- Raman spectroscopy (2)
- Subtilases (2)
- Subtilisin (2)
- capacitive field-effect sensors (2)
- gold nanoparticles (2)
- hydrogen peroxide (2)
- light-addressable potentiometric sensor (2)
- microfluidics (2)
- penicillinase (2)
- (Bio)degradation (1)
- Acylation (1)
- Alginate beads (1)
- Alkalihalobacillus okhensis (1)
- Bacillus atrophaeus spores (1)
- Bioabsorbable (1)
- Biocatalysis (1)
- Biosurfactants (1)
- Broad pH spectrum (1)
- CNOT (1)
- CRISPR/Cas9 (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Chaperone (1)
- Chaperone co-expression (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- C–V method (1)
- DNA biosensor (1)
- DPA (dipicolinic acid) (1)
- Dehydrogenase (1)
- Detergent protease (1)
- Diaphorase (1)
- E. coli detection (1)
- EIS capacitive sensor (1)
- Electrolyte–insulator–semiconductor (1)
- Enzymatic biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Extracellular enzymes (1)
- Field effect (1)
- Field-effect biosensor (1)
- Field-effect sensor (1)
- Gold nanoparticles (1)
- Halotolerant protease (1)
- Hydrogen peroxide (1)
- Hypersecretion (1)
- Impedance spectroscopy (1)
- Inclusion bodies (1)
- Lab-on-Chip (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- MOS (1)
- Marker-free mutagenesis (1)
- Master stamp (1)
- Multianalyte detection (1)
- Multicell (1)
- Multiplexing (1)
- Negative impedance convertor (1)
- O2 plasma (1)
- Organic light-emitting diode display (1)
- Penicillin (1)
- Photolithographic mimics (1)
- Plant virus (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Quartz crystal microbalance (1)
- Real-time monitoring (1)
- Resistive temperature detector (1)
- Resonance-mode measurement (1)
- Silk fibroin (1)
- Simultaneous determination (1)
- Sn₃O₄ (1)
- Stenotrophomonas maltophilia (1)
- Sterilisation process (1)
- Streptomyces griseus (1)
- Streptomyces lividans (1)
- Surface imprinted polymer (1)
- TMV adsorption (1)
- Ta₂O₅ gate (1)
- Tobacco mosaic virus (TMV) (1)
- Uracil-phosphoribosyltransferase (1)
- Vibrio natriegens (1)
- XOR (1)
- Zeta potential (1)
- acetoin (1)
- acetoin reductase (1)
- actuator-sensor system (1)
- alcoholic beverages (1)
- aminooctanethiol (1)
- amperometric biosensors (1)
- annealing (1)
- aquaculture (1)
- artificial olfactory image (1)
- aseptic parameters (1)
- aspergillus (1)
- atomic layer deposition (1)
- bi-enzyme biosensor (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biosensor (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- capacitive EIS sensor (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive model (1)
- carbon electrodes (1)
- catalytic metal (1)
- chemical sensor (1)
- chip-based sensor setup (1)
- colorization (1)
- control gate (1)
- coupled Néel–Brownian relaxation dynamics (1)
- detection of charged macromolecules (1)
- detergent protease (1)
- electrical conductivity of liquids (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electrolyte-insulator-semiconductor capacitors (1)
- electronic nose (1)
- encapsulation materials (1)
- endospores (1)
- enzymatic biosensor (1)
- enzyme cascade (1)
- enzyme kinetics (1)
- enzyme-logic gate (1)
- equivalent circuit (1)
- fibroin (1)
- field-effect structure (1)
- filamentous fungi (1)
- frequency mixing (1)
- gas sensor (1)
- gaseous hydrogen peroxide (1)
- genome engineering (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- graphene oxide (1)
- halotolerant protease (1)
- heavy metals (1)
- high-alkaline subtilisin (1)
- horseradish peroxidase (HRP) (1)
- hydroxylation (1)
- immobilization (1)
- impedance spectroscopy (1)
- key performance indicators (1)
- layer-by-layer technique (1)
- light-addressable electrode (1)
- light-addressing technologies (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic sensors (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- metal-oxide-semiconductor structure (1)
- micromagnetic simulation (1)
- multi-sensing platform (1)
- multianalyte detection (1)
- multiparametric immunoassays (1)
- multiplex detection (1)
- nanobelts (1)
- nanomaterials (1)
- nanoparticle coverage (1)
- on-chip integrated addressable EISCAP sensors (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organosilanes (1)
- oxidative stable protease (1)
- pH sensors (1)
- penicillin (1)
- photoelectrochemistry (1)
- plant virus detection (1)
- plug-based microfluidic device (1)
- polyaniline (1)
- polystyrene sulfonate (1)
- recombinant expression (1)
- scanned light pulse technique (1)
- silanization (1)
- spore kill rate (1)
- sterilisation (1)
- sterility (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- temperature (1)
- thermometry (1)
- titanium dioxide photoanode (1)
- turnip vein clearing virus (TVCV) (1)
- ultrathin gate insulators (1)
- urease (1)
- validation methods (1)
- visualization (1)
- α-aminoacylase (1)
- ε-lysine acylase (1)
The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed.
The artificial olfactory image was proposed by Lundström et al. in 1991 as a new strategy for an electronic nose system which generated a two-dimensional mapping to be interpreted as a fingerprint of the detected gas species. The potential distribution generated by the catalytic metals integrated into a semiconductor field-effect structure was read as a photocurrent signal generated by scanning light pulses. The impact of the proposed technology spread beyond gas sensing, inspiring the development of various imaging modalities based on the light addressing of field-effect structures to obtain spatial maps of pH distribution, ions, molecules, and impedance, and these modalities have been applied in both biological and non-biological systems. These light-addressing technologies have been further developed to realize the position control of a faradaic current on the electrode surface for localized electrochemical reactions and amperometric measurements, as well as the actuation of liquids in microfluidic devices.
Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species
(2017)
A light-addressable potentiometric sensor (LAPS) is a semiconductor-based chemical sensor, in which a measurement site on the sensing surface is defined by illumination. This light addressability can be applied to visualize the spatial distribution of pH or the concentration of a specific chemical species, with potential applications in the fields of chemistry, materials science, biology, and medicine. In this review, the features of this chemical imaging sensor technology are compared with those of other technologies. Instrumentation, principles of operation, and various measurement modes of chemical imaging sensor systems are described. The review discusses and summarizes state-of-the-art technologies, especially with regard to the spatial resolution and measurement speed; for example, a high spatial resolution in a submicron range and a readout speed in the range of several tens of thousands of pixels per second have been achieved with the LAPS. The possibility of combining this technology with microfluidic devices and other potential future developments are discussed.