Article
Refine
Year of publication
- 2024 (34)
- 2023 (65)
- 2022 (78)
- 2021 (86)
- 2020 (102)
- 2019 (95)
- 2018 (85)
- 2017 (72)
- 2016 (79)
- 2015 (83)
- 2014 (93)
- 2013 (97)
- 2012 (82)
- 2011 (130)
- 2010 (121)
- 2009 (121)
- 2008 (103)
- 2007 (94)
- 2006 (86)
- 2005 (99)
- 2004 (131)
- 2003 (74)
- 2002 (92)
- 2001 (88)
- 2000 (84)
- 1999 (88)
- 1998 (82)
- 1997 (79)
- 1996 (70)
- 1995 (68)
- 1994 (77)
- 1993 (51)
- 1992 (48)
- 1991 (25)
- 1990 (35)
- 1989 (38)
- 1988 (54)
- 1987 (32)
- 1986 (18)
- 1985 (32)
- 1984 (18)
- 1983 (17)
- 1982 (26)
- 1981 (18)
- 1980 (35)
- 1979 (23)
- 1978 (30)
- 1977 (14)
- 1976 (13)
- 1975 (10)
- 1974 (3)
- 1972 (2)
- 1971 (1)
- 1968 (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (1359)
- INB - Institut für Nano- und Biotechnologien (503)
- Fachbereich Chemie und Biotechnologie (472)
- Fachbereich Elektrotechnik und Informationstechnik (414)
- IfB - Institut für Bioengineering (411)
- Fachbereich Energietechnik (361)
- Fachbereich Luft- und Raumfahrttechnik (254)
- Fachbereich Maschinenbau und Mechatronik (149)
- Fachbereich Wirtschaftswissenschaften (116)
- Fachbereich Bauingenieurwesen (69)
- Solar-Institut Jülich (43)
- ECSM European Center for Sustainable Mobility (32)
- Sonstiges (21)
- Institut fuer Angewandte Polymerchemie (20)
- Nowum-Energy (18)
- Freshman Institute (17)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (15)
- Fachbereich Gestaltung (12)
- Fachbereich Architektur (11)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (5)
- IMP - Institut für Mikrowellen- und Plasmatechnik (3)
- Arbeitsstelle fuer Hochschuldidaktik und Studienberatung (2)
- Kommission für Forschung und Entwicklung (2)
- FH Aachen (1)
- IBB - Institut für Baustoffe und Baukonstruktionen (1)
- Kommission für Planung und Finanzen (1)
- Senat (1)
Language
- English (3282) (remove)
Document Type
- Article (3282) (remove)
Keywords
- Einspielen <Werkstoff> (7)
- avalanche (5)
- Earthquake (4)
- FEM (4)
- Finite-Elemente-Methode (4)
- LAPS (4)
- biosensors (4)
- field-effect sensor (4)
- frequency mixing magnetic detection (4)
- CellDrum (3)
Objective
Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels.
Methods
152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions.
Results
In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained.
Conclusion
This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention.
Algorithmic design and resilience assessment of energy efficient high-rise water supply systems
(2018)
High-rise water supply systems provide water flow and suitable pressure in all levels of tall buildings. To design such state-of-the-art systems, the consideration of energy efficiency and the anticipation of component failures are mandatory. In this paper, we use Mixed-Integer Nonlinear Programming to compute an optimal placement of pipes and pumps, as well as an optimal control strategy.Moreover, we consider the resilience of the system to pump failures. A resilient system is able to fulfill a predefined minimum functionality even though components fail or are restricted in their normal usage. We present models to measure and optimize the resilience. To demonstrate our approach, we design and analyze an optimal resilient decentralized water supply system inspired by a real-life hotel building.