Refine
Year of publication
- 2019 (192) (remove)
Document Type
- Article (95)
- Conference Proceeding (74)
- Part of a Book (15)
- Book (4)
- Doctoral Thesis (3)
- Talk (1)
Language
- English (192) (remove)
Keywords
- Enterprise Architecture (2)
- Seismic design (2)
- Achilles tendon (1)
- Advanced driver assistance systems (ADAS/AD) (1)
- Aircraft design (1)
- Analytics (1)
- Architectural gear ratio (1)
- Assistive technology (1)
- Automatic control (1)
- BEV (1)
- Bioeconomy (1)
- Biorefinery definitions (1)
- Case Study (1)
- Change Management (1)
- Combustion (1)
- Components (1)
- Corporate Culture (1)
- Correlations (1)
- Decentral (1)
- Design examples (1)
- Design rules (1)
- Digital Age (1)
- Diversity Management (1)
- Drag (1)
- Earthquake (1)
- Emilia-Romagna earthquake (1)
- Empirical consequence curves (1)
- Empirical fragility functions (1)
- Engineering (1)
- Engineering optimization (1)
- Eurocode 8 (1)
- Force (1)
- Gearbox (1)
- Geometry (1)
- Goodness-of-fit test (1)
- Graph Theory (1)
- Green aircraft (1)
- Gust wind response (1)
- Human-Computer interaction (1)
- Hybrid-electric aircraft (1)
- Hydrogen (1)
- ISO 26262 (1)
- In-plane (1)
- Industrial units (1)
- Innovation Management (1)
- Introduction (1)
- Isolation (1)
- Iterative learning control (1)
- Knee (1)
- Load modeling (1)
- Low NOx (1)
- Low emission (1)
- Machine learning (1)
- Mechanical (1)
- Mixed-integer nonlinear black-box optimization (1)
- Multi-sample problem (1)
- On-site (1)
- Optimization (1)
- Out-of-plane (1)
- PBEE (1)
- Parametric bootstrap (1)
- Powertrain (1)
- Pre-treatment (1)
- Precast buildings (1)
- Preface (1)
- Process schemes (1)
- Product family optimization (1)
- Pushover analysis (1)
- Rehabilitation engineering (1)
- Renewable resources (1)
- Resilience Assessment (1)
- Response spectrum (1)
- Robotic Process Automation (1)
- Running (1)
- Safety of the intended functionality (SOTIF) (1)
- Safety-critical systems validation (1)
- Seismic (1)
- Silos (1)
- Software Robots (1)
- Spectral analysis (1)
- Statistics (1)
- Stiffness (1)
- Tanks (1)
- Tendon properties (1)
- Training (1)
- Unmanned Air Vehicle (1)
- Volume of confidence regions (1)
- WLTP (1)
- Water Supply System (1)
- Wind turbulence (1)
- asymptotic relative efficiency (1)
- concentrating collector (1)
- frequency mixing magnetic detection (1)
- likelihood ratio test (1)
- magnetic actuation (1)
- magnetic sandwich immunoassay (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- point-focussing system (1)
- raytracing (1)
- responsive space (1)
- small solar system body characterisation (1)
- small spacecraft asteroid lander (1)
- small spacecraft solar sail (1)
- solar process heat (1)
- superparamagnetic bead (1)
- system engineering (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (63)
- IfB - Institut für Bioengineering (40)
- Fachbereich Luft- und Raumfahrttechnik (37)
- Fachbereich Elektrotechnik und Informationstechnik (30)
- INB - Institut für Nano- und Biotechnologien (20)
- Fachbereich Energietechnik (19)
- Fachbereich Maschinenbau und Mechatronik (16)
- Fachbereich Chemie und Biotechnologie (12)
- Fachbereich Bauingenieurwesen (8)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (8)
- Solar-Institut Jülich (6)
- Fachbereich Wirtschaftswissenschaften (3)
- ECSM European Center for Sustainable Mobility (2)
- Fachbereich Gestaltung (2)
- Nowum-Energy (2)
- Institut fuer Angewandte Polymerchemie (1)
Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection
(2019)
Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin’s B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more
than 700 ng/ml.