Refine
Year of publication
- 2018 (254) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (67)
- Fachbereich Elektrotechnik und Informationstechnik (43)
- IfB - Institut für Bioengineering (39)
- INB - Institut für Nano- und Biotechnologien (25)
- Fachbereich Maschinenbau und Mechatronik (24)
- Fachbereich Luft- und Raumfahrttechnik (23)
- Fachbereich Chemie und Biotechnologie (22)
- Fachbereich Energietechnik (22)
- Fachbereich Wirtschaftswissenschaften (20)
- Fachbereich Bauingenieurwesen (16)
Has Fulltext
- no (254) (remove)
Document Type
- Article (127)
- Conference Proceeding (74)
- Part of a Book (31)
- Book (11)
- Conference: Meeting Abstract (2)
- Doctoral Thesis (2)
- Patent (2)
- Working Paper (2)
- Conference Poster (1)
- Other (1)
Keywords
- Datenschutz (2)
- Digitale Transformation (2)
- Energy efficiency (2)
- Engineering optimization (2)
- Literaturanalyse (2)
- MINLP (2)
- Pump System (2)
- Serious Game (2)
- Water (2)
- Actors (1)
- Agility (1)
- Antarctica (1)
- Awareness (1)
- Bahadur efficiency (1)
- Bioeconomy (1)
- Bioethanol (1)
- Biorefinery (1)
- Biorefinery definitions (1)
- Bladder (1)
- Booster Stations (1)
- Buffering Capacity (1)
- CDG (1)
- Chance Constraint (1)
- Chemical imaging (1)
- Cloud Computing (1)
- Coat protein (1)
- Competence Developing Game (1)
- Conditions (1)
- Conductive boundary condition (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Datenschutzgrundverordnung (1)
- Datenschutzrecht (1)
- Design process (1)
- Dry surfaces (1)
- EBSCO Discovery Service (1)
- EU-DS-GVO (1)
- EUDSGVO (1)
- Engineering Application (1)
- Enterprise Architecture (1)
- Enzyme nanocarrier (1)
- Equivalence test (1)
- Field-effect device (1)
- Forschungsprozess (1)
- GOSSAMER-1 (1)
- Geschäftsprozessmanagement (1)
- Global optimization (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Goodness-of-fit tests for uniformity (1)
- Growth modelling (1)
- IBM Watson Explorer (1)
- INODIS (1)
- IT-Sicherheit (1)
- Identitätsmanagement (1)
- Informationsgetriebene Geschäftsmodelle (1)
- Integrated empirical distribution (survival) function (1)
- Internet der Dinge (1)
- Introduction (1)
- Inverse scattering (1)
- Jupiter (1)
- Kernel density estimator (1)
- Lab-on-Chip (1)
- Latin Hypercube Sampling (1)
- Length of confidence intervals (1)
- Light-addressable potentiometric sensor (1)
- Lignocellulose feedstook (1)
- Literatur-analyse-prozess (1)
- Literaturdaten (1)
- Literature review (1)
- MASCOT (1)
- Manifestations (1)
- Mars (1)
- Mechanical simulation (1)
- Microbial adhesion (1)
- Mixed-integer nonlinear problem (1)
- Monetarisierung (1)
- Multi-criteria optimization (1)
- Muscle fibers (1)
- Network (1)
- Numerical inversion of Laplace transforms (1)
- Paper recycling (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Pitman efficiency (1)
- Planetary exploration (1)
- Planning process (1)
- Player Types (1)
- Potentiometry (1)
- Process engineering (1)
- Process schemes (1)
- Projektbeispiele (1)
- Prozessautomatisierung (1)
- Qualitative Wertschöpfungsanalyse (1)
- RC frames (1)
- Reconstruction (1)
- Rehabilitation Technology and Prosthetics (1)
- Renewable resources (1)
- Research process (1)
- Sampling methods (1)
- Softwareroboter (1)
- Stochastic Programming (1)
- Story (1)
- Structure and Stages (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Swabbing (1)
- Technische Schutzmaßnahmen (1)
- Text Analytics (1)
- Text Analytics (1)
- Text analytics (1)
- Text mining (1)
- Tobacco mosaic virus (TMV) (1)
- Tools (1)
- Transmission eigenvalues (1)
- Uncertainty (1)
- Ureter (1)
- Video Game (1)
- Water Distribution (1)
- Water Supply Networks (1)
- Wilcoxon tests (1)
- Wissenstransfer (1)
- achilles tendon (1)
- agile (1)
- business simulation (1)
- design of technical systems (1)
- earthquakes (1)
- energy absorption (1)
- energy dissipation (1)
- frequency mixing (1)
- functional data (1)
- habitability (1)
- huge dimensional data (1)
- ice moons (1)
- icy moons (1)
- in-plane and out-of-plane failure (1)
- legal obligations (1)
- life detection (1)
- magnetic beads (1)
- magnetic sensing (1)
- mathematical optimization (1)
- mechanical buffer (1)
- multiple NEA rendezvous (1)
- optimization (1)
- product liability (1)
- remote sensing (1)
- resilience (1)
- separable Hilbert space (1)
- slum classification (1)
- small spacecraft (1)
- solar sail (1)
- space missions (1)
- stiffness (1)
- superparamagnetic nanoparticles (1)
- tablet game (1)
- underwater vehicle (1)
- water supply design (1)
Stahlbetonrahmentragwerke mit Mauerwerksausfachungen weisen nach Erdbebenereignissen häufig schwere Schäden auf, da die Ausfachungen ohne weitere konstruktive Maßnahmen mit vollem Kontakt zum Stahlbetonrahmen eingemauert werden. Durch die unplanmäßige Beteiligung am horizontalen Lastabtrag erfahren die Ausfachungen Belastungen in Wandebene und beeinflussen das globale Schwingungsverhalten der Rahmentragwerke. In Kombination mit den gleichzeitig auftretenden seismischen Trägheitskräften senkrecht zur Wand führt dies in vielen Fällen zu einem Versagen der mit niedrigen Festigkeiten ausgeführten Ausfachungen. Dies war der Anlass in dem europäischen Forschungsprojekt INSYSME ein Entkopplungssystem zu entwickeln, mit dem Rahmen und Ausfachung durch ein spezielles Profil aus Elastomeren entkoppelt werden.
Das Profil ermöglicht Relativverschiebungen zwischen Rahmen und Ausfachung und stellt gleichzeitig die Aufnahme von Belastungen senkrecht zur Wand sicher. Der Beitrag erläutert zunächst den Aufbau des Systems und gibt einen Überblick über die in Kleinbauteilversuchen ermittelten Tragfähigkeiten. Zudem werden experimentelle Untersuchungen an mit hochwärmedämmenden Mauerziegeln ausgefachten Stahlbetonrahmen mit und ohne Entkopplungssystem für getrennte und kombinierte Belastungen in und senkrecht zur Wandebene vorgestellt. Auf Grundlage einer Versuchsauswertung und eines Ergebnisvergleichs werden Wirkungsweise und Effektivität des entwickelten Entkopplungssystems demonstriert.
Enzyme und Biosensorik
(2018)
Enzymbasierte Biosensoren finden seit mehr als fünf Jahrzehnten einen prosperierenden Wachstumsmarkt und werden zunehmend auch in biotechnologischen Prozessen eingesetzt. In diesem Kapitel werden, ausgehend vom Sensorbegriff und typischen Kenngrößen für Biosensoren (Abschn. 18.1), elektrochemische Enzym-Biosensoren vorgestellt und deren typischen Einsatzgebiete diskutiert (Abschn. 18.2). Ein Blick über den „Tellerrand“ hinaus zeigt alternative Transduktorprinzipien (Abschn. 18.3) und führt abschließend in aktuelle Forschungstrends ein (Abschn. 18.4).
Die Batterie ist eine der absolut zentralen Komponenten des Elektrofahrzeugs. Die serielle Entwicklung und Produktion dieser Batterien und die Verbesserung der Leistungen wird entscheidend für den Erfolg der Elektromobilität sein. Die Batterie ist jedoch nicht das einzige elektrofahrzeugspezifische System, das neu entwickelt, umkonzipiert oder verbessert werden muss. So sind ebenso die Entwicklung der neuen Fahrzeugstruktur sowie des elektrifizierten Antriebsstranges Teil dieses Kapitels. Weiterhin wird ein Blick auf das bedeutende Thema des Thermomanagements geworfen.
For fuel flexibility enhancement hydrogen represents a possible alternative gas turbine fuel within future low emission power generation, in case of hydrogen production by the use of renewable energy sources such as wind energy or biomass. Kawasaki Heavy Industries, Ltd. (KHI) has research and development projects for future hydrogen society; production of hydrogen gas, refinement and liquefaction for transportation and storage, and utilization with gas turbine / gas engine for the generation of electricity. In the development of hydrogen gas turbines, a key technology is the stable and low NOx hydrogen combustion, especially Dry Low Emission (DLE) or Dry Low NOx (DLN) hydrogen combustion. Due to the large difference in the physical properties of hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for DLE hydrogen combustion. Thus, the development of DLE hydrogen combustion technologies is an essential and challenging task for the future of hydrogen fueled gas turbines. The DLE Micro-Mix combustion principle for hydrogen fuel has been in development for many years to significantly reduce NOx emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized “diffusion-type” flames. The major advantages of this combustion principle are the inherent safety against flashback and the low NOx-emissions due to a very short residence time of the reactants in the flame region of the micro-flames.
The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design.
New information regarding the influence of a stepped chute on the hydraulic performance of the United States Bureau of Reclamation (Reclamation) Type III hydraulic jump stilling basin is presented for design (steady) and adverse (decreasing tailwater) conditions. Using published experimental data and computational fluid dynamics (CFD) models, this paper presents a detailed comparison between smooth-chute and stepped-chute configurations for chute slopes of 0.8H:1V and 4H:1V and Froude numbers (F) ranging from 3.1 to 9.5 for a Type III basin designed for F = 8. For both stepped and smooth chutes, the relative role of each basin element was quantified, up to the most hydraulic extreme case of jump sweep-out. It was found that, relative to a smooth chute, the turbulence generated by a stepped chute causes a higher maximum velocity decay within the stilling basin, which represents an enhancement of the Type III basin’s performance but also a change in the relative role of the basin elements. Results provide insight into the ability of the CFD models [unsteady Reynolds-averaged Navier-Stokes (RANS) equations with renormalization group (RNG) k-ϵ turbulence model and volume-of-fluid (VOF) for free surface tracking] to predict the transient basin flow structure and velocity profiles. Type III basins can perform adequately with a stepped chute despite the effects steps have on the relative role of each basin element. It is concluded that the classic Type III basin design, based upon methodology by reclamation specific to smooth chutes, can be hydraulically improved for the case of stepped chutes for design and adverse flow conditions using the information presented herein.
Background
Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097.
Results
Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth.
Conclusions
The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.