Refine
Year of publication
Document Type
- Article (1578)
- Conference Proceeding (239)
- Book (96)
- Part of a Book (59)
- Doctoral Thesis (27)
- Patent (17)
- Report (15)
- Other (8)
- Habilitation (4)
- Lecture (3)
- Preprint (3)
- Course Material (1)
- Review (1)
- Talk (1)
Keywords
- Biosensor (25)
- Finite-Elemente-Methode (16)
- CAD (15)
- civil engineering (14)
- Bauingenieurwesen (13)
- Einspielen <Werkstoff> (13)
- shakedown analysis (9)
- FEM (6)
- Limit analysis (6)
- Shakedown analysis (6)
- limit analysis (6)
- Clusterion (5)
- Air purification (4)
- Einspielanalyse (4)
- Hämoglobin (4)
- LAPS (4)
- Lipopolysaccharide (4)
- Luftreiniger (4)
- Natural language processing (4)
- Plasmacluster ion technology (4)
- Raumluft (4)
- Shakedown (4)
- Technische Mechanik (4)
- Traglast (4)
- Traglastanalyse (4)
- hydrogen peroxide (4)
- shakedown (4)
- CellDrum (3)
- Field-effect sensor (3)
- Information extraction (3)
- Kohlenstofffaser (3)
- Label-free detection (3)
- Light-addressable potentiometric sensor (3)
- Paired sample (3)
- Sonde (3)
- biosensor (3)
- biosensors (3)
- impedance spectroscopy (3)
- lipopolysaccharides (3)
- ratchetting (3)
- Analytischer Zulaessigkeitsnachweis (2)
- Architektur (2)
- Bacillus atrophaeus (2)
- Biocomposites (2)
- Bruchmechanik (2)
- Capacitive field-effect sensor (2)
- Clustering (2)
- Druckbeanspruchung (2)
- Druckbehälter (2)
- Druckbelastung (2)
- Einspiel-Analyse (2)
- Eisschicht (2)
- Empirical process (2)
- Erythrozyt (2)
- Fehlerstellen (2)
- Fibroblast (2)
- Force (2)
- Goodness-of-fit test (2)
- Incomplete data (2)
- Independence test (2)
- Iterative learning control (2)
- Machine learning (2)
- Natural fibres (2)
- Parametric bootstrap (2)
- Pflanzenphysiologie (2)
- Pflanzenscanner (2)
- Polymer-matrix composites (2)
- Potentiometry (2)
- Raman spectroscopy (2)
- Ratcheting (2)
- Rohr (2)
- Rohrbruch (2)
- Stahl (2)
- Stickstoffmonoxid (2)
- Stiffness (2)
- Stress concentrations (2)
- Tobacco mosaic virus (TMV) (2)
- acetoin (2)
- architecture (2)
- biopotential electrodes (2)
- burst pressure (2)
- burst tests (2)
- capacitive field-effect sensors (2)
- carbonized rice husk (2)
- celldrum technology (2)
- constructive alignment (2)
- damage (2)
- examination (2)
- field-effect sensor (2)
- flaw (2)
- frequency mixing magnetic detection (2)
- gas sensor (2)
- likelihood ratio test (2)
- limit load (2)
- load limit (2)
- locomotion (2)
- long-term retention (2)
- multimodal (2)
- muscle fascicle behavior (2)
- nanostructured carbonized plant parts (2)
- nanostrukturierte carbonisierte Pflanzenteile (2)
- nitric oxide gas (2)
- not identically distributed (2)
- pipes (2)
- plant scanner (2)
- practical learning (2)
- sterilisation (2)
- surface modification (2)
- tension–torsion loading (2)
- tobacco mosaic virus (TMV) (2)
- ultrasound (2)
- ultrasound imaging (2)
- vessels (2)
- (Bio)degradation (1)
- 3-nitrofluoranthene (1)
- Acceleration (1)
- Achilles tendon (1)
- Active learning (1)
- Adaptive control (1)
- Adsorption (1)
- Afterload (1)
- Ageing (1)
- Agent-based simulation (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Anastomose (1)
- Anastomosis (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Architectural design (1)
- Architectural gear ratio (1)
- Arthosetherapie (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Asymptotic relative efficiency (1)
- Aufschlagversuch (1)
- Autofluoreszenzverfahren (1)
- Autolysis (1)
- Automatic control (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- BTEX compounds (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Bakterien (1)
- Balance (1)
- Basis Reduktion (1)
- Basis reduction (1)
- Bein (1)
- Bicharakteristikenverfahren (1)
- Bio-Sensors (1)
- Bioabsorbable (1)
- Biomechanical simulation (1)
- Biomechanics (1)
- Biomechanik (1)
- Biomedizinische Technik (1)
- Biomolecular logic gate (1)
- Biophoton (1)
- Bioreaktor (1)
- Biosensorik (1)
- Biosolubilization (1)
- Bladder (1)
- Blitzschutz (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Bone sawing (1)
- Booster Station (1)
- Bootstrap (1)
- Bootstrapping (1)
- Brennkraftmaschine (1)
- Brennstoffeinspritzsystem (1)
- Brownian Pillow (1)
- CAD ; (1)
- CNOT (1)
- CO (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Censored data (1)
- Chance constrained programming (1)
- Chemical images (1)
- Chemical imaging (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Choleratoxin B (1)
- Circular Dichroism (1)
- Cloud Computing (1)
- Cloud Service Broker (1)
- Co-managed care (1)
- Coat protein (1)
- Coefficient of ocular rigidity (1)
- Collective risk model (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conducing polymer (1)
- Conductive Boundary Condition (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Convex optimization (1)
- Corneo-scleral shell (1)
- Cost-effectiveness (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Cross border adjustment mechanism (1)
- Crámer–von-Mises distance (1)
- Culture media (1)
- C–V method (1)
- DNA (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Dattel (1)
- Decomposition (1)
- Deep Learning (1)
- Deep learning (1)
- Deformation (1)
- Dehydrogenase (1)
- Dekontamination (1)
- Design-by-analysis (1)
- Diaphorase (1)
- Differential tonometry (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discrete Optimization (1)
- Distorsion des oberen Sprunggelenks (1)
- Druckgeräte (1)
- Drug simulation (1)
- Dry surfaces (1)
- E-Mobility (1)
- ECT (1)
- EEG (1)
- EIS capacitive sensor (1)
- ELISA (1)
- EPN (1)
- ES-FEM (1)
- Effizienz (1)
- Eigenvalue trajectories (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastizität (1)
- Elastodynamik (1)
- Elastostatics (1)
- Elderly (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Elektrodynamik (1)
- Elektroenzephalographie (1)
- Elektromyographie (1)
- Elektrostimulation (1)
- Elemental (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Endothelzelle (1)
- Energy market design (1)
- Energy-intensive industry (1)
- Enterprise information systems (1)
- Environmental impact (1)
- Enzymatic biosensor (1)
- Enzyme biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme nanocarrier (1)
- Enzyme-linked immunosorbent assay (1)
- Epithel (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- Evolution of damage (1)
- Exact Ilyushin yield surface (1)
- Experiment (1)
- Extension fracture (1)
- Extension strain criterion (1)
- Extensor (1)
- External knee adduction moments (1)
- Eyeball (1)
- FEM-Programm (1)
- FEM-computation (1)
- FGF23 (1)
- FS-FEM (1)
- Fall prevention (1)
- Fault approximation (1)
- Fault detection (1)
- Festkörper (1)
- Field effect (1)
- Field-effect biosensor (1)
- Field-effect device (1)
- Finite element analysis (1)
- Finite element analysis (FEA) (1)
- Finite element method (1)
- Finite element modelling (1)
- First Order Reliabiblity Method (1)
- First-order reliability method (1)
- Fließgrenze (1)
- Floor prices (1)
- Fluorescence (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Fußball (1)
- GaAs hot electron injector (1)
- Gamma distribution (1)
- Gas sensor (1)
- Geriatric (1)
- German (1)
- Glaucoma (1)
- Global and local collapse (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Gold nanoparticle (1)
- Gold nanoparticles (1)
- Gonarthrose (1)
- Goodness-of-fit tests for uniformity (1)
- Grenzwertberechnung (1)
- Grid Computing (1)
- Ground-level falls (1)
- Growth modelling (1)
- Gunn diode (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Handbike (1)
- Harnleiter (1)
- Heart tissue culture (1)
- Heavy metal detection (1)
- Hemoglobin structure (1)
- Heterostructure (1)
- High throughput experimentation (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Hotplate (1)
- Human Factors (1)
- Human-Computer interaction (1)
- Hydrodynamik (1)
- Hydrogel (1)
- Hydrogen peroxide (1)
- Hydrogen sensor (1)
- Hypothesentests (1)
- Hämoglobinstruktur (1)
- I3S 2005 (1)
- ISFET (1)
- Image Reconstruction (1)
- Impedance Spectroscopy (1)
- Impedance spectroscopy (1)
- Induced pluripotent stem cells (1)
- Information Extraction (1)
- Information Integration Tools (1)
- Inotropic compounds (1)
- Integrated empirical distribution (survival) function (1)
- Interior transmission problem (1)
- International Symposium on Sensor Science (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering problem (1)
- Ion channels (1)
- Kinematics (1)
- Kinetic energy (1)
- Kinetics (1)
- Klotho (1)
- Knee (1)
- Kniegelenkarthrose (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Knowledge Management (1)
- Krypton (1)
- Krypton-85 (1)
- Körpertemperatur (1)
- LED chip (1)
- LISA (1)
- LPS (1)
- Lab-on-Chip (1)
- Langevin theory (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Level sensor (1)
- Lichtstreuungsbasierte Instrumente (1)
- Light-addressable Potentiometric Sensor (1)
- Liver (1)
- Load modeling (1)
- Long COVID (1)
- MBST (1)
- MCDA (1)
- MEMS (1)
- MOS (1)
- Magnetic nanoparticles (1)
- Main sensitivity (1)
- Manipulated variables (1)
- Marginal homogeneity (1)
- Marginal homogeneity test (1)
- Market modeling (1)
- Materialermüdung (1)
- Mechanical simulation (1)
- Mechanics (1)
- Mechanische Beanspruchung (1)
- Mechanotransduction (1)
- Medusomyces gisevi (1)
- Metascintillator (1)
- Microbial adhesion (1)
- Microcirculation (1)
- Micromagnetic simulation (1)
- Microreactors (1)
- Mild cognitive impairment (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Model-driven software engineering (1)
- Mohr–Coulomb criterion (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional wave propagation (1)
- Multi-sample problem (1)
- Multianalyte detection (1)
- Multicell (1)
- Multimode failure (1)
- Multiple TOF kernels (1)
- Multiplexing (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Muscle fibers (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Nano Materials (1)
- Nanomaterial (1)
- Nanoparticles (1)
- Nanopartikel (1)
- Nanostructuring (1)
- Nanotechnologie (1)
- Nanotechnology ; Microelectronics ; Biosensors ; Superconductor ; MEMS (1)
- Natriumhypochlorit (1)
- Natural Language Processing (1)
- Natural language understanding (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Neuromuskuläres System (1)
- Niacin (1)
- Nichtlineare Gleichung (1)
- Nichtlineare Optimierung (1)
- Nichtlineare Welle (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-linear optimization (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Ontologie <Wissensverarbeitung> (1)
- Ontology Engineering (1)
- Organic light-emitting diode display (1)
- Organkultur (1)
- Organophosphorus (1)
- Ostazine Orange (1)
- Osteoporose (1)
- Osteoporosis (1)
- PFM (1)
- PTH (1)
- Paralympic sport (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Penicillin (1)
- Permeability (1)
- Permeabilität (1)
- Peroxidase (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Phenylalanine determination (1)
- Phosphate (1)
- Physiology (1)
- Plant virus (1)
- Plastizität (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Post-COVID-19 syndrome (1)
- Preference assessment (1)
- Pressure loaded crack-face (1)
- Pressure-volume relationship (1)
- Prevention (1)
- Process model (1)
- Product-integration (1)
- Profile Extraction (1)
- Profile extraction (1)
- Progressive plastic deformation (1)
- Prophylaxis (1)
- Proteine (1)
- Proximal humerus fracture (1)
- Pseudomonas putida (1)
- Psychiatrische Biomarker (1)
- Pulsations (1)
- Pump System (1)
- Quartz crystal nanobalance (QCN) (1)
- Quartz micro balances (1)
- Query learning (1)
- RVA (1)
- Random variable (1)
- Ratchetting (1)
- Raumfahrt (1)
- Reaction-diffusion (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Reconstruction (1)
- Red blood cell storage (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Rehabilitationsmedizin (1)
- Rehabilitatives Training (1)
- Relation classification (1)
- Reliability analysis (1)
- Reliability of structures (1)
- Reproducible research (1)
- Resampling test (1)
- Resistive temperature detector (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Robotik (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- Sampling methods (1)
- ScaLAPACK (1)
- Schienbeinschoner (1)
- Schlafspindeldetektion (1)
- Schwammknochen (1)
- Semi-parametric random censorship model (1)
- Sensitivity (1)
- Sepsis (1)
- Septic cardiomyopathy (1)
- Shakedown criterion (1)
- Silk fibroin (1)
- Simulation (1)
- Simultaneous determination (1)
- Skeletal muscle (1)
- Sleep EEG (1)
- Small Aral Sea (1)
- Sn₃O₄ (1)
- Software and systems modeling (1)
- Solid amalgam electrodes (1)
- Spleen (1)
- Sprunggelenkorthesen (1)
- Statics (1)
- Steel industry (1)
- Sterilisation process (1)
- Stochastic programming (1)
- Strukturanalyse (1)
- SunRav BookEditor (1)
- Supraleiter (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Swabbing (1)
- TMV adsorption (1)
- TOF PET (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (TOR) (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Text Mining (1)
- Text mining (1)
- Thiamine (1)
- Tin oxide (1)
- Tinetti test (1)
- Tissue Engineering (1)
- Tobacco mosaic virus (1)
- Torsion (1)
- Torsionsbelastung (1)
- Tragfähigkeit (1)
- Training (1)
- Trainingsgerät (1)
- Transmission Eigenvalues (1)
- Trinkwassersicherheit (1)
- Trustworthy artificial intelligence (1)
- UML (1)
- Ultrasound (1)
- Uniaxial compression test (1)
- Unified Modeling Language (1)
- Ureter (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vergleich von Experimenten (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Volumes of confidence regions (1)
- Wafer (1)
- Wasserbrücke (1)
- Wasserstoffperoxid (1)
- Wellen (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Workflow (1)
- Workflow Orchestration (1)
- Wundheilung (1)
- XOR (1)
- Xenon (1)
- Zeta potential (1)
- Zug-Druck Belastung (1)
- Zug-Druck-Beanspruchung (1)
- Zug-Druck-Belastung (1)
- acetoin reductase (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- activated nanostructured carbon (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- aktivierte nanostrukturierte Kohlenstofffaser (1)
- alcoholic beverages (1)
- allocation (1)
- alternierend Verformbarkeit (1)
- ammonia gas sensors (1)
- amperometric biosensors (1)
- amperometric sensor (1)
- anaesthetic complications (1)
- anisotropy (1)
- ankle braces (1)
- ankle sprain (1)
- annealing (1)
- antimony doped tin oxide (1)
- aortic perfusion (1)
- aromatic amines (1)
- arthrosis therapy (1)
- artificial olfactory image (1)
- asymptotic relative efficiency (1)
- atomic layer deposition (1)
- autofluorescence-based detection system (1)
- barium strontium titanate (1)
- biaxial tensile experiment (1)
- bicharacteristics (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biomechanics (1)
- bone density (1)
- bone structure (1)
- bootstrap (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- cancellous bone (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive field-effect biosensor (1)
- capacitive field-effect sensor (1)
- capillary micro-droplet cell (1)
- carbon electrodes (1)
- carcinogens (1)
- cardiomyocyte biomechanics (1)
- catalytic decomposition (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- chemical reduction method (1)
- chemical sensor (1)
- cholera toxin B (1)
- cognitive impairment (1)
- community dwelling (1)
- complete block symmetry (1)
- computational fluid dynamics analysis (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- contractile tension (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- cross sensitivity (1)
- cytosolic water diffusion (1)
- date palm tree (1)
- dental trauma (1)
- design-by-analysis (1)
- dialysis (1)
- difficult airway (1)
- direct method (1)
- distance learning (1)
- distorted element (1)
- doped metal oxide (1)
- doped silicon (1)
- doping (1)
- double-lumen tube intubation (1)
- drinking water safety (1)
- drop jump (1)
- e-books (1)
- e-issues (1)
- ecological structure (1)
- efficiency (1)
- eigensolvers (1)
- elastic solids (1)
- electrical capacitance tomography (1)
- electro-migration (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electromyography (1)
- electronic nose (1)
- electronic noses dendronized polymers inverted mesa technology (1)
- encapsulation materials (1)
- endoluminal (1)
- endospores (1)
- energy absorption (1)
- energy dissipation (1)
- enzymatic (bio)degradation (1)
- enzymatic biosensor (1)
- enzymatic methods (1)
- enzyme cascade (1)
- enzyme immobilisation (1)
- enzyme immobilization (1)
- epithelization (1)
- exchangeability test (1)
- extracorporeal membrane oxygenation (1)
- fatigue analyses (1)
- fenitrothion (1)
- fibroin (1)
- fibulare Bandruptur (1)
- field-effect structure (1)
- finite element analysis (1)
- fluidic (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- frequency mixing (1)
- functional data (1)
- gait (1)
- gas sensor array (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- gonarthrosis (1)
- goodness-of-fit test (1)
- graphene oxide (1)
- healthy aging (1)
- heater metallisation (1)
- heavy metals (1)
- hemoglobin (1)
- hemoglobin dynamics (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- high-k material (1)
- high-temperature stability (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- human dermal fibroblasts (1)
- humic acid (1)
- humidity (1)
- hydrogel (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- image sensor (1)
- imaging (1)
- immobilization (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- independence test (1)
- intraclass correlation coefficient (1)
- ion-selective electrodes (1)
- key performance indicators (1)
- kontraktile Spannung (1)
- konvexe Optimierung (1)
- krypton xenon hydrate (1)
- lab-on-a-chip (1)
- lab-on-chip (1)
- lable-free detection (1)
- large language models (1)
- layer expansion (1)
- layer-by-layer technique (1)
- lenslet array (1)
- light scattering analysis (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- lightning flash (1)
- lignite (1)
- limit and shakedown analysis (1)
- linear kinematic hardening (1)
- lipopolysaccharide (1)
- load carrying capacity (1)
- lower bound theorem (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic frequency mixing technique (1)
- magnetic nanoparticles (1)
- magnetic particles (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- material shakedown (1)
- matrix method (1)
- mechanical buffer (1)
- mechanical waves (1)
- metagenomics (1)
- metal oxide (1)
- metal-oxide-semiconductor structure (1)
- microbial diversity (1)
- micromagnetic simulation (1)
- microreactor (1)
- microwave generation (1)
- modeling biosensor (1)
- modelling (1)
- modified electrode (1)
- multi-functional material (1)
- multi-interface measurement (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- nanomaterials (1)
- naphtols (1)
- nitrogen oxides (1)
- non-simplex S-FEM elements (1)
- nonlinear kinematic hardening (1)
- nonlinear optimization (1)
- nonlinear solids (1)
- nonlinear tensor constitutive equation (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organic PVC membranes (1)
- organosilanes (1)
- overload (1)
- pH sensors (1)
- pH-based biosensing (1)
- parabolic flight (1)
- pattern-size reduction (1)
- penicillin (1)
- penicillinase (1)
- performance analysis (1)
- performance testing (1)
- phenols (1)
- photoelectrochemistry (1)
- physiology (1)
- plant stress (1)
- plant virus detection (1)
- plasma generated ions (1)
- plastic deformation (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- polyaniline (1)
- polymer composites (1)
- porous Pt electrode (1)
- portfolio risk (1)
- prevention (1)
- principal component (1)
- probabilistic fracture mechanics (1)
- protein (1)
- psychosocial (1)
- quantum charging (1)
- random effects (1)
- random effects meta-regression model (1)
- rehabilitation (1)
- reliability (1)
- reliability analysis (1)
- reliability of structures (1)
- retinal microvasculature (1)
- retinal vessels (1)
- rhAPC (1)
- running (1)
- rupture of the fibular ligament (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- screen-printing (1)
- second-order reliability method (1)
- self-aligned patterning (1)
- semantic role labeling (1)
- sensing properties (1)
- sensors (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- shakedown analyses (1)
- shotgun sequencing (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- smooth muscle contraction (1)
- softs (1)
- spatial resolution (1)
- speaker attribution (1)
- sprint start (1)
- standard error of measurement (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- subsurface ice research (1)
- subsurface probe (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- survival (1)
- swift heavy ions (1)
- temperature (1)
- tendon rupture (1)
- test-retest reliability (1)
- testing hypotheses (1)
- thermal ratcheting (1)
- thick-film technology (1)
- thin-film microsensors (1)
- tilted constant illumination (1)
- titanium dioxide photoanode (1)
- training simulator (1)
- tri-lineage differentiation (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- ultrathin gate insulators (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- validation methods (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual reality (1)
- viscoelasticity (1)
- visualization (1)
- voltammetry (1)
- wafer-level testing (1)
- walking (1)
- walking gait (1)
- water bridge phenomenon (1)
- wound healing (1)
- yield stress (1)
- · Psychiatrische Erkrankungen/Diagnostik (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (2052) (remove)
Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.
Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.
Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor’s recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential.
A new formulation to calculate the shakedown limit load of Kirchhoff plates under stochastic conditions of strength is developed. Direct structural reliability design by chance con-strained programming is based on the prescribed failure probabilities, which is an effective approach of stochastic programming if it can be formulated as an equivalent deterministic optimization problem. We restrict uncertainty to strength, the loading is still deterministic. A new formulation is derived in case of random strength with lognormal distribution. Upper bound and lower bound shakedown load factors are calculated simultaneously by a dual algorithm.
Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies for the classical sleep stages of Wake, REM, and Non-REM. Meanwhile, it has been recognized that the statistics of transitional stages such as pre-REM, found between Non-REM and REM, may hold additional insight into the physiology of sleep and are now under vivid investigation. We propose a classification system based on a simple neural network architecture that scores the classical stages as well as pre-REM sleep in mice. When restricted to the classical stages, the optimized network showed state-of-the-art classification performance with an out-of-sample F1 score of 0.95 in male C57BL/6J mice. When unrestricted, the network showed lower F1 scores on pre-REM (0.5) compared to the classical stages. The result is comparable to previous attempts to score transitional stages in other species such as transition sleep in rats or N1 sleep in humans. Nevertheless, we observed that the sequence of predictions including pre-REM typically transitioned from Non-REM to REM reflecting sleep dynamics observed by human scorers. Our findings provide further evidence for the difficulty of scoring transitional sleep stages, likely because such stages of sleep are under-represented in typical data sets or show large inter-scorer variability. We further provide our source code and an online platform to run predictions with our trained network.