Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (2072) (remove)
Document Type
- Article (1591)
- Conference Proceeding (241)
- Book (96)
- Part of a Book (62)
- Doctoral Thesis (27)
- Patent (17)
- Report (15)
- Other (9)
- Habilitation (4)
- Lecture (3)
Keywords
- Biosensor (25)
- Finite-Elemente-Methode (16)
- CAD (15)
- civil engineering (14)
- Bauingenieurwesen (13)
- Einspielen <Werkstoff> (13)
- shakedown analysis (9)
- FEM (6)
- Limit analysis (6)
- Shakedown analysis (6)
- limit analysis (6)
- Clusterion (5)
- Air purification (4)
- Einspielanalyse (4)
- Hämoglobin (4)
- LAPS (4)
- Lipopolysaccharide (4)
- Luftreiniger (4)
- Natural language processing (4)
- Plasmacluster ion technology (4)
- Raumluft (4)
- Shakedown (4)
- Technische Mechanik (4)
- Traglast (4)
- Traglastanalyse (4)
- hydrogen peroxide (4)
- impedance spectroscopy (4)
- shakedown (4)
- CellDrum (3)
- Field-effect sensor (3)
- Information extraction (3)
- Kohlenstofffaser (3)
- Label-free detection (3)
- Light-addressable potentiometric sensor (3)
- Paired sample (3)
- Sonde (3)
- biosensor (3)
- biosensors (3)
- lipopolysaccharides (3)
- ratchetting (3)
- Analytischer Zulaessigkeitsnachweis (2)
- Architektur (2)
- Bacillus atrophaeus (2)
- Biocomposites (2)
- Boundary integral equations (2)
- Bruchmechanik (2)
- Capacitive field-effect sensor (2)
- Clustering (2)
- Conductive boundary condition (2)
- Druckbeanspruchung (2)
- Druckbehälter (2)
- Druckbelastung (2)
- Einspiel-Analyse (2)
- Eisschicht (2)
- Empirical process (2)
- Erythrozyt (2)
- Fehlerstellen (2)
- Fibroblast (2)
- Force (2)
- Goodness-of-fit test (2)
- Incomplete data (2)
- Independence test (2)
- Iterative learning control (2)
- Machine learning (2)
- Natural fibres (2)
- Parametric bootstrap (2)
- Pflanzenphysiologie (2)
- Pflanzenscanner (2)
- Polymer-matrix composites (2)
- Potentiometry (2)
- Raman spectroscopy (2)
- Ratcheting (2)
- Rohr (2)
- Rohrbruch (2)
- Stahl (2)
- Stickstoffmonoxid (2)
- Stiffness (2)
- Stress concentrations (2)
- Tobacco mosaic virus (TMV) (2)
- Transmission eigenvalues (2)
- acetoin (2)
- architecture (2)
- biopotential electrodes (2)
- burst pressure (2)
- burst tests (2)
- capacitive field-effect sensors (2)
- carbonized rice husk (2)
- celldrum technology (2)
- constructive alignment (2)
- damage (2)
- examination (2)
- field-effect sensor (2)
- flaw (2)
- frequency mixing magnetic detection (2)
- gas sensor (2)
- likelihood ratio test (2)
- limit load (2)
- load limit (2)
- locomotion (2)
- long-term retention (2)
- multimodal (2)
- muscle fascicle behavior (2)
- nanostructured carbonized plant parts (2)
- nanostrukturierte carbonisierte Pflanzenteile (2)
- nitric oxide gas (2)
- not identically distributed (2)
- pipes (2)
- plant scanner (2)
- practical learning (2)
- sterilisation (2)
- surface modification (2)
- tension–torsion loading (2)
- tobacco mosaic virus (TMV) (2)
- ultrasound (2)
- ultrasound imaging (2)
- vessels (2)
- (Bio)degradation (1)
- 3-nitrofluoranthene (1)
- Acceleration (1)
- Achilles tendon (1)
- Active learning (1)
- Adaptive control (1)
- Adsorption (1)
- Afterload (1)
- Ageing (1)
- Agent-based simulation (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Anastomose (1)
- Anastomosis (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Architectural design (1)
- Architectural gear ratio (1)
- Arthosetherapie (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Asymptotic relative efficiency (1)
- Aufschlagversuch (1)
- Autofluoreszenzverfahren (1)
- Autolysis (1)
- Automatic control (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- BTEX compounds (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Bakterien (1)
- Balance (1)
- Basis Reduktion (1)
- Basis reduction (1)
- Bein (1)
- Bicharakteristikenverfahren (1)
- Bio-Sensors (1)
- Bioabsorbable (1)
- Biomechanical simulation (1)
- Biomechanics (1)
- Biomechanik (1)
- Biomedizinische Technik (1)
- Biomolecular logic gate (1)
- Biophoton (1)
- Bioreaktor (1)
- Biosensorik (1)
- Biosolubilization (1)
- Bladder (1)
- Blitzschutz (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Bone sawing (1)
- Booster Station (1)
- Bootstrap (1)
- Bootstrapping (1)
- Boundary integral equations, (1)
- Brennkraftmaschine (1)
- Brennstoffeinspritzsystem (1)
- Brownian Pillow (1)
- CAD ; (1)
- CNOT (1)
- CO (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Censored data (1)
- Chance constrained programming (1)
- Chemical images (1)
- Chemical imaging (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Choleratoxin B (1)
- Circular Dichroism (1)
- Cloud Computing (1)
- Cloud Service Broker (1)
- Co-managed care (1)
- Coat protein (1)
- Coefficient of ocular rigidity (1)
- Collective risk model (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conducing polymer (1)
- Conductive Boundary Condition (1)
- Conservation laws (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Convex optimization (1)
- Corneo-scleral shell (1)
- Cost-effectiveness (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Cross border adjustment mechanism (1)
- Crámer–von-Mises distance (1)
- Culture media (1)
- C–V method (1)
- DNA (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Dattel (1)
- Decomposition (1)
- Deep Learning (1)
- Deep learning (1)
- Deformation (1)
- Dehydrogenase (1)
- Dekontamination (1)
- Design-by-analysis (1)
- Diaphorase (1)
- Differential tonometry (1)
- Dimensional splitting (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discrete Optimization (1)
- Distorsion des oberen Sprunggelenks (1)
- Druckgeräte (1)
- Drug simulation (1)
- Dry surfaces (1)
- E-Mobility (1)
- E. coli detection (1)
- ECT (1)
- EEG (1)
- EIS capacitive sensor (1)
- ELISA (1)
- EPN (1)
- ES-FEM (1)
- Effizienz (1)
- Eigenvalue trajectories (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastizität (1)
- Elastodynamik (1)
- Elastostatics (1)
- Elderly (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Elektrodynamik (1)
- Elektroenzephalographie (1)
- Elektromyographie (1)
- Elektrostimulation (1)
- Elemental (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Endothelzelle (1)
- Energy market design (1)
- Energy-intensive industry (1)
- Enterprise information systems (1)
- Entropy solution (1)
- Environmental impact (1)
- Enzymatic biosensor (1)
- Enzyme biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme nanocarrier (1)
- Enzyme-linked immunosorbent assay (1)
- Epithel (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- Evolution of damage (1)
- Exact Ilyushin yield surface (1)
- Experiment (1)
- Exponential Euler scheme, (1)
- Exponential time differencing (1)
- Extension fracture (1)
- Extension strain criterion (1)
- Extensor (1)
- External knee adduction moments (1)
- Eyeball (1)
- FEM-Programm (1)
- FEM-computation (1)
- FGF23 (1)
- FS-FEM (1)
- Fall prevention (1)
- Fault approximation (1)
- Fault detection (1)
- Festkörper (1)
- Field effect (1)
- Field-effect biosensor (1)
- Field-effect device (1)
- Finite difference methods (1)
- Finite element analysis (1)
- Finite element analysis (FEA) (1)
- Finite element method (1)
- Finite element modelling (1)
- First Order Reliabiblity Method (1)
- First-order reliability method (1)
- Fließgrenze (1)
- Floor prices (1)
- Fluorescence (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Fußball (1)
- GaAs hot electron injector (1)
- Gamma distribution (1)
- Gas sensor (1)
- Geriatric (1)
- German (1)
- Glaucoma (1)
- Global and local collapse (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Gold nanoparticle (1)
- Gold nanoparticles (1)
- Gonarthrose (1)
- Goodness-of-fit tests for uniformity (1)
- Grenzwertberechnung (1)
- Grid Computing (1)
- Ground-level falls (1)
- Growth modelling (1)
- Gunn diode (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Handbike (1)
- Harnleiter (1)
- Heart tissue culture (1)
- Heavy metal detection (1)
- Helmholtz equation (1)
- Hemoglobin structure (1)
- Heterostructure (1)
- High throughput experimentation (1)
- Higher-order codes (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Hotplate (1)
- Human Factors (1)
- Human-Computer interaction (1)
- Hydrodynamik (1)
- Hydrogel (1)
- Hydrogen peroxide (1)
- Hydrogen sensor (1)
- Hypothesentests (1)
- Hämoglobinstruktur (1)
- I3S 2005 (1)
- ISFET (1)
- Image Reconstruction (1)
- Impedance Spectroscopy (1)
- Impedance spectroscopy (1)
- Implicit methods (1)
- Induced pluripotent stem cells (1)
- Information Extraction (1)
- Information Integration Tools (1)
- Inotropic compounds (1)
- Integrated empirical distribution (survival) function (1)
- Interior Neumann eigenvalues (1)
- Interior transmission eigenvalues (1)
- Interior transmission problem (1)
- International Symposium on Sensor Science (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering (1)
- Inverse scattering problem (1)
- Inverse spectral problem (1)
- Ion channels (1)
- Kinematics (1)
- Kinetic energy (1)
- Kinetics (1)
- Klotho (1)
- Knee (1)
- Kniegelenkarthrose (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Knowledge Management (1)
- Krypton (1)
- Krypton-85 (1)
- Körpertemperatur (1)
- LED chip (1)
- LISA (1)
- LPS (1)
- Lab-on-Chip (1)
- Langevin theory (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Level sensor (1)
- Lichtstreuungsbasierte Instrumente (1)
- Light-addressable Potentiometric Sensor (1)
- Liver (1)
- Load modeling (1)
- Long COVID (1)
- MBST (1)
- MCDA (1)
- MEMS (1)
- MOS (1)
- Magnetic nanoparticles (1)
- Main sensitivity (1)
- Manipulated variables (1)
- Marginal homogeneity (1)
- Marginal homogeneity test (1)
- Market modeling (1)
- Master stamp (1)
- Materialermüdung (1)
- Matrix exponential (1)
- Mechanical simulation (1)
- Mechanics (1)
- Mechanische Beanspruchung (1)
- Mechanotransduction (1)
- Medusomyces gisevi (1)
- Metascintillator (1)
- Microbial adhesion (1)
- Microcirculation (1)
- Micromagnetic simulation (1)
- Microreactors (1)
- Mild cognitive impairment (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Model-driven software engineering (1)
- Mohr–Coulomb criterion (1)
- Monotone methods (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional partial differential equations (1)
- Multi-dimensional wave propagation (1)
- Multi-sample problem (1)
- Multianalyte detection (1)
- Multicell (1)
- Multimode failure (1)
- Multiple TOF kernels (1)
- Multiplexing (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Muscle fibers (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Nano Materials (1)
- Nanomaterial (1)
- Nanoparticles (1)
- Nanopartikel (1)
- Nanostructuring (1)
- Nanotechnologie (1)
- Nanotechnology ; Microelectronics ; Biosensors ; Superconductor ; MEMS (1)
- Natriumhypochlorit (1)
- Natural Language Processing (1)
- Natural language understanding (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Neuromuskuläres System (1)
- Niacin (1)
- Nichtlineare Gleichung (1)
- Nichtlineare Optimierung (1)
- Nichtlineare Welle (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-linear optimization (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nonlinear PDEs (1)
- Nonlinear eigenvalue problems (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- Numerics (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Ontologie <Wissensverarbeitung> (1)
- Ontology Engineering (1)
- Organic light-emitting diode display (1)
- Organkultur (1)
- Organophosphorus (1)
- Ostazine Orange (1)
- Osteoporose (1)
- Osteoporosis (1)
- PFM (1)
- PTH (1)
- Parabolic SPDEs (1)
- Paralympic sport (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Penicillin (1)
- Permeability (1)
- Permeabilität (1)
- Peroxidase (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Phenylalanine determination (1)
- Phosphate (1)
- Photolithographic mimics (1)
- Physiology (1)
- Plant virus (1)
- Plastizität (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Post-COVID-19 syndrome (1)
- Potential theory (1)
- Preference assessment (1)
- Pressure loaded crack-face (1)
- Pressure-volume relationship (1)
- Prevention (1)
- Process model (1)
- Product-integration (1)
- Profile Extraction (1)
- Profile extraction (1)
- Progressive plastic deformation (1)
- Prophylaxis (1)
- Proteine (1)
- Proximal humerus fracture (1)
- Pseudomonas putida (1)
- Psychiatrische Biomarker (1)
- Pulsations (1)
- Pump System (1)
- Quartz crystal microbalance (1)
- Quartz crystal nanobalance (QCN) (1)
- Quartz micro balances (1)
- Query learning (1)
- RVA (1)
- Random variable (1)
- Ratchetting (1)
- Raumfahrt (1)
- Reaction-diffusion (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Reconstruction (1)
- Red blood cell storage (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Rehabilitationsmedizin (1)
- Rehabilitatives Training (1)
- Relation classification (1)
- Reliability analysis (1)
- Reliability of structures (1)
- Reproducible research (1)
- Resampling test (1)
- Resistive temperature detector (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Robotik (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- Sampling methods (1)
- ScaLAPACK (1)
- Schienbeinschoner (1)
- Schlafspindeldetektion (1)
- Schwammknochen (1)
- Semi-parametric random censorship model (1)
- Sensitivity (1)
- Sepsis (1)
- Septic cardiomyopathy (1)
- Shakedown criterion (1)
- Silk fibroin (1)
- Simulation (1)
- Simultaneous determination (1)
- Skeletal muscle (1)
- Sleep EEG (1)
- Small Aral Sea (1)
- Sn₃O₄ (1)
- Software and systems modeling (1)
- Solid amalgam electrodes (1)
- Source term (1)
- Spleen (1)
- Sprunggelenkorthesen (1)
- Statics (1)
- Steel industry (1)
- Sterilisation process (1)
- Stochastic programming (1)
- Strukturanalyse (1)
- SunRav BookEditor (1)
- Supraleiter (1)
- Surface imprinted polymer (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Swabbing (1)
- TMV adsorption (1)
- TOF PET (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (TOR) (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Text Mining (1)
- Text mining (1)
- Thiamine (1)
- Tin oxide (1)
- Tinetti test (1)
- Tissue Engineering (1)
- Tobacco mosaic virus (1)
- Torsion (1)
- Torsionsbelastung (1)
- Tragfähigkeit (1)
- Training (1)
- Trainingsgerät (1)
- Transmission Eigenvalues (1)
- Trinkwassersicherheit (1)
- Trustworthy artificial intelligence (1)
- UML (1)
- Ultrasound (1)
- Uniaxial compression test (1)
- Unified Modeling Language (1)
- Ureter (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vergleich von Experimenten (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Volumes of confidence regions (1)
- Wafer (1)
- Wasserbrücke (1)
- Wasserstoffperoxid (1)
- Wellen (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Workflow (1)
- Workflow Orchestration (1)
- Wundheilung (1)
- XOR (1)
- Xenon (1)
- Zeta potential (1)
- Zug-Druck Belastung (1)
- Zug-Druck-Beanspruchung (1)
- Zug-Druck-Belastung (1)
- acetoin reductase (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- activated nanostructured carbon (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- aktivierte nanostrukturierte Kohlenstofffaser (1)
- alcoholic beverages (1)
- allocation (1)
- alternierend Verformbarkeit (1)
- ammonia gas sensors (1)
- amperometric biosensors (1)
- amperometric sensor (1)
- anaesthetic complications (1)
- anisotropy (1)
- ankle braces (1)
- ankle sprain (1)
- annealing (1)
- antimony doped tin oxide (1)
- aortic perfusion (1)
- aquaculture (1)
- aromatic amines (1)
- arthrosis therapy (1)
- artificial olfactory image (1)
- asymptotic relative efficiency (1)
- atomic layer deposition (1)
- autofluorescence-based detection system (1)
- barium strontium titanate (1)
- biaxial tensile experiment (1)
- bicharacteristics (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biomechanics (1)
- bone density (1)
- bone structure (1)
- bootstrap (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- cancellous bone (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive field-effect biosensor (1)
- capacitive field-effect sensor (1)
- capillary micro-droplet cell (1)
- carbon electrodes (1)
- carcinogens (1)
- cardiomyocyte biomechanics (1)
- catalytic decomposition (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- chemical reduction method (1)
- chemical sensor (1)
- chip-based sensor setup (1)
- cholera toxin B (1)
- cognitive impairment (1)
- community dwelling (1)
- complete block symmetry (1)
- computational fluid dynamics analysis (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- contractile tension (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- cross sensitivity (1)
- cytosolic water diffusion (1)
- date palm tree (1)
- dental trauma (1)
- design-by-analysis (1)
- dialysis (1)
- difficult airway (1)
- direct method (1)
- distance learning (1)
- distorted element (1)
- doped metal oxide (1)
- doped silicon (1)
- doping (1)
- double-lumen tube intubation (1)
- drinking water safety (1)
- drop jump (1)
- e-books (1)
- e-issues (1)
- ecological structure (1)
- efficiency (1)
- eigensolvers (1)
- elastic scattering (1)
- elastic solids (1)
- electrical capacitance tomography (1)
- electrical conductivity of liquids (1)
- electro-migration (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electromyography (1)
- electronic nose (1)
- electronic noses dendronized polymers inverted mesa technology (1)
- encapsulation materials (1)
- endoluminal (1)
- endospores (1)
- energy absorption (1)
- energy dissipation (1)
- enzymatic (bio)degradation (1)
- enzymatic biosensor (1)
- enzymatic methods (1)
- enzyme cascade (1)
- enzyme immobilisation (1)
- enzyme immobilization (1)
- epithelization (1)
- exchangeability test (1)
- extracorporeal membrane oxygenation (1)
- fatigue analyses (1)
- fenitrothion (1)
- fibroin (1)
- fibulare Bandruptur (1)
- field-effect structure (1)
- finite element analysis (1)
- fluidic (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- frequency mixing (1)
- functional data (1)
- gait (1)
- gas sensor array (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- gonarthrosis (1)
- goodness-of-fit test (1)
- graphene oxide (1)
- healthy aging (1)
- heater metallisation (1)
- heavy metals (1)
- hemoglobin (1)
- hemoglobin dynamics (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- high-k material (1)
- high-temperature stability (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- human dermal fibroblasts (1)
- humic acid (1)
- humidity (1)
- hydrogel (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- image sensor (1)
- imaging (1)
- immobilization (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- independence test (1)
- intraclass correlation coefficient (1)
- ion-selective electrodes (1)
- key performance indicators (1)
- kontraktile Spannung (1)
- konvexe Optimierung (1)
- krypton xenon hydrate (1)
- lab-on-a-chip (1)
- lab-on-chip (1)
- lable-free detection (1)
- large language models (1)
- layer expansion (1)
- layer-by-layer technique (1)
- lenslet array (1)
- light scattering analysis (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- lightning flash (1)
- lignite (1)
- limit and shakedown analysis (1)
- linear kinematic hardening (1)
- lipopolysaccharide (1)
- load carrying capacity (1)
- lower bound theorem (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic frequency mixing technique (1)
- magnetic nanoparticles (1)
- magnetic particles (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- material shakedown (1)
- matrix method (1)
- mechanical buffer (1)
- mechanical waves (1)
- metagenomics (1)
- metal oxide (1)
- metal-oxide-semiconductor structure (1)
- method of fundamental solutions (1)
- microbial diversity (1)
- microfluidics (1)
- micromagnetic simulation (1)
- microreactor (1)
- microwave generation (1)
- modeling biosensor (1)
- modelling (1)
- modified electrode (1)
- multi-functional material (1)
- multi-interface measurement (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- nanomaterials (1)
- naphtols (1)
- nitrogen oxides (1)
- non-simplex S-FEM elements (1)
- nonlinear kinematic hardening (1)
- nonlinear optimization (1)
- nonlinear solids (1)
- nonlinear tensor constitutive equation (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organic PVC membranes (1)
- organosilanes (1)
- overload (1)
- pH sensors (1)
- pH-based biosensing (1)
- parabolic flight (1)
- pattern-size reduction (1)
- penicillin (1)
- penicillinase (1)
- performance analysis (1)
- performance testing (1)
- phenols (1)
- photoelectrochemistry (1)
- physiology (1)
- plant stress (1)
- plant virus detection (1)
- plasma generated ions (1)
- plastic deformation (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- polyaniline (1)
- polymer composites (1)
- porous Pt electrode (1)
- portfolio risk (1)
- prevention (1)
- principal component (1)
- probabilistic fracture mechanics (1)
- protein (1)
- psychosocial (1)
- quantum charging (1)
- random effects (1)
- random effects meta-regression model (1)
- rehabilitation (1)
- reliability (1)
- reliability analysis (1)
- reliability of structures (1)
- retinal microvasculature (1)
- retinal vessels (1)
- rhAPC (1)
- running (1)
- rupture of the fibular ligament (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- screen-printing (1)
- second-order reliability method (1)
- self-aligned patterning (1)
- semantic role labeling (1)
- sensing properties (1)
- sensors (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- shakedown analyses (1)
- shotgun sequencing (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- smooth muscle contraction (1)
- softs (1)
- spatial resolution (1)
- speaker attribution (1)
- sprint start (1)
- standard error of measurement (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- subsurface ice research (1)
- subsurface probe (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- survival (1)
- swift heavy ions (1)
- temperature (1)
- tendon rupture (1)
- test-retest reliability (1)
- testing hypotheses (1)
- thermal ratcheting (1)
- thermometry (1)
- thick-film technology (1)
- thin-film microsensors (1)
- tilted constant illumination (1)
- titanium dioxide photoanode (1)
- training simulator (1)
- tri-lineage differentiation (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- ultrathin gate insulators (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- validation methods (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual reality (1)
- viscoelasticity (1)
- visualization (1)
- voltammetry (1)
- wafer-level testing (1)
- walking (1)
- walking gait (1)
- water bridge phenomenon (1)
- wound healing (1)
- yield stress (1)
- · Psychiatrische Erkrankungen/Diagnostik (1)
The integration of biomolecular logic principles with electronic transducers allows designing novel digital biosensors with direct electrical output, logically triggered drug-release, and closed-loop sense/act/treat systems. This opens new opportunities for advanced personalized medicine in the context of theranostics. In the present work, we will discuss selected examples of recent developments in the field of interfacing enzyme logic gates with electrodes and semiconductor field-effect devices. Special attention is given to an enzyme OR/Reset logic gate based on a capacitive field-effect electrolyte-insulator-semiconductor sensor modified with a multi-enzyme membrane. Further examples are a digital adrenaline biosensor based on an AND logic gate with binary YES/NO output and an integrated closed-loop sense/act/treat system comprising an amperometric glucose sensor, a hydrogel actuator, and an insulin (drug) sensor.
A physically coupled finite element method (FEM) model is developed to study the response behavior of a calorimetric gas sensor. The modeled sensor serves as a monitoring device of the concentration of gaseous hydrogen peroxide (H2 O2) in a high temperature mixture stream in aseptic sterilization processes. The principle of operation of a calorimetric H2 O2 sensor is analyzed and the results of the numerical model have been validated by using previously published sensor experiments. The deviation in the results between the FEM model and experimental data are presented and discussed.
A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric sensor with an electrolyte/insulator/semiconductor (EIS) structure, which is able to monitor analyte concentrations of (bio-)chemical species in aqueous solutions in a spatially resolved way. Therefore, it is also an appropriate tool to record 2D-chemical images of concentration variations on the sensor surface. In the present work, two differential, LAPS-based measurement principles are introduced to determine the metabolic activity of Escherichia coli (E. coli) K12 and Chinese hamster ovary (CHO) cells as test microorganisms. Hereby, we focus on i) the determination of the extracellular acidification rate (ΔpH/min) after adding glucose solutions to the cell suspensions; and ii) recording the amplitude increase of the photocurrent (Iph) related to the produced acids from E. coli K12 bacteria and CHO cells on the sensor surface by 2D-chemical imaging. For this purpose, 3D-printed multi-chamber structures were developed and mounted on the planar sensor-chip surface to define four independent compartments, enabling differential measurements with varying cell concentrations. The differential concept allows eliminating unwanted drift effects and, with the four-chamber structures, measurements on the different cell concentrations were performed simultaneously, thus reducing also the overall measuring time.
The incorporation of nanomaterials that are biocompatible with different types of biological compounds has allowed the development of a new generation of biosensors applied especially in the biomedical field. In particular, the integration of film-based nanomaterials employed in field-effect devices can be interesting to develop biosensors with enhanced properties. In this paper, we studied the fabrication of sensitive nanofilms combining ZnO nanocrystals and carbon nanotubes (CNTs), prepared by means of the layer-by-layer (LbL) technique, in a capacitive electrolyte-insulator-semiconductor (EIS) structure for detecting glucose and urea. The ZnO nanocrystals were incorporated in a polymeric matrix of poly(allylamine) hydrochloride (PAH), and arranged with multi-walled CNTs in a LbL PAH-ZnO/CNTs film architecture onto EIS chips. The electrochemical characterizations were performed by capacitance–voltage and constant capacitance measurements, while the morphology of the films was characterized by atomic force microscopy. The enzymes glucose oxidase and urease were immobilized on film’s surface for detection of glucose and urea, respectively. In order to obtain glucose and urea biosensors with optimized amount of sensitive films, we investigated the ideal number of bilayers for each detection system. The glucose biosensor showed better sensitivity and output signal for an LbL PAH-ZnO/CNTs nanofilm with 10 bilayers. On the other hand, the urea biosensor presented enhanced properties even for the first bilayer, exhibiting high sensitivity and output signal. The presence of the LbL PAH-ZnO/CNTs films led to biosensors with better sensitivity and enhanced response signal, demonstrating that the adequate use of nanostructured films is feasible for proof-of-concept biosensors with improved properties that may be employed for biomedical applications.
Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems.
The gene encoding a putative (R,R)-butane-2,3-diol dehydrogenase (bdhA) from Bacillus clausii DSM 8716T was isolated, sequenced and expressed in Escherichia coli. The amino acid sequence of the encoded protein is only distantly related to previously studied enzymes (identity 33–43%) and exhibited some uncharted peculiarities. An N-terminally StrepII-tagged enzyme variant was purified and initially characterized. The isolated enzyme catalyzed the (R)-specific oxidation of (R,R)- and meso-butane-2,3-diol to (R)- and (S)-acetoin with specific activities of 12 U/mg and 23 U/mg, respectively. Likewise, racemic acetoin was reduced with a specific activity of up to 115 U/mg yielding a mixture of (R,R)- and meso-butane-2,3-diol, while the enzyme reduced butane-2,3-dione (Vmax 74 U/mg) solely to (R,R)-butane-2,3-diol via (R)-acetoin. For these reactions only activity with the co-substrates NADH/NAD+ was observed. The enzyme accepted a selection of vicinal diketones, α-hydroxy ketones and vicinal diols as alternative substrates. Although the physiological function of the enzyme in B. clausii remains elusive, the data presented herein clearly demonstrates that the encoded enzyme is a genuine (R,R)-butane-2,3-diol dehydrogenase with potential for applications in biocatalysis and sensor development.