Refine
Year of publication
- 2010 (343) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (73)
- Fachbereich Wirtschaftswissenschaften (41)
- IfB - Institut für Bioengineering (40)
- Fachbereich Elektrotechnik und Informationstechnik (36)
- Fachbereich Chemie und Biotechnologie (35)
- Fachbereich Energietechnik (35)
- Fachbereich Maschinenbau und Mechatronik (31)
- Fachbereich Bauingenieurwesen (24)
- Fachbereich Luft- und Raumfahrttechnik (24)
- INB - Institut für Nano- und Biotechnologien (23)
Language
- English (187)
- German (153)
- Italian (2)
- Multiple languages (1)
Document Type
- Article (140)
- Conference Proceeding (100)
- Book (38)
- Part of a Book (23)
- Conference: Meeting Abstract (20)
- Patent (7)
- Report (5)
- Doctoral Thesis (2)
- Other (2)
- Part of a Periodical (2)
Keywords
- Aachen / Fachhochschule Aachen (3)
- Aachen University of Applied Sciences (3)
- FH Aachen (2)
- Geschichte (2)
- avalanche (2)
- humans (2)
- Adsorbentien (1)
- Cardiovascular MRI (1)
- Cardiovascular Magnetic Resonance (1)
- Commercial Vehicle (1)
The integration of nanostructured films containing biomolecules and silicon-based technologies is a promising direction for reaching miniaturized biosensors that exhibit high sensitivity and selectivity. A challenge, however, is to avoid cross talk among sensing units in an array with multiple sensors located on a small area. In this letter, we describe an array of 16 sensing units of a light-addressable potentiometric sensor (LAPS), which was made with layer-by-layer (LbL) films of a poly(amidomine) dendrimer (PAMAM) and single-walled carbon nanotubes (SWNTs), coated with a layer of the enzyme penicillinase. A visual inspection of the data from constant-current measurements with liquid samples containing distinct concentrations of penicillin, glucose, or a buffer indicated a possible cross talk between units that contained penicillinase and those that did not. With the use of multidimensional data projection techniques, normally employed in information visualization methods, we managed to distinguish the results from the modified LAPS, even in cases where the units were adjacent to each other. Furthermore, the plots generated with the interactive document map (IDMAP) projection technique enabled the distinction of the different concentrations of penicillin, from 5 mmol L−1 down to 0.5 mmol L−1. Data visualization also confirmed the enhanced performance of the sensing units containing carbon nanotubes, consistent with the analysis of results for LAPS sensors. The use of visual analytics, as with projection methods, may be essential to handle a large amount of data generated in multiple sensor arrays to achieve high performance in miniaturized systems
Background: To elaborate the impact of new haemostatic agents we developed an instrument for the pressure-controlled induction of blunt liver injuries in a porcine animal model. Materials and Methods: A dilutional coagulopathy of 80% of animal blood volume was induced in 9 anaesthetized pigs. Animals were randomly assigned to be injured with a force of 112 Newton (N) (n = 1), 224 ± 19 N (n = 4) or 355 ± 35 N (n = 4). The impact of injury was measured by blood loss, survival time and coagulation parameters. Liver histology was obtained to evaluate the degree of liver injury. Results: The profound haemodilution resulted in a significant alteration of all coagulation parameters. After inflicting the injury with 355 ± 35 N, both the survival time (30 ± 9 min; p = 0.006) and blood loss (68 ± 16 ml min–1, p = 0.002) were significantly different as compared to injuries with 224 ± 19 N (survival time: 76 ± 20 min, blood loss: 23 ± 4 ml min–1). In contrast, an injury with 112 N led to an insignificant blood loss of only 239 ml. Conclusion: We developed a pressure-controlled clamp that allows for the induction of blunt liver traumas with highly reproducible injuries with a positive correlation with blood loss and survival.
Organisation
(2010)
Unter Energieeffizienz wird verstanden, dass ein definiertes Ziel mit möglichst wenig Energie erreicht wird. Im Beitrag wird zunächst eine Formel zur Berechnung der Gesamtenergieeffizienz eines Gebäudes angegeben. Darauf aufbauend wird ein 3-Säulen-Modell zur Energieeinsparung vorgeschlagen. Es beinhaltet vereinfachte Verfahren zur Berechnung der Betriebseigenschaften von Heizanlagen, raumlufttechnischen Anlagen und Kühl- und Kaltwasseranlagen. Am Beispiel einer RLT-Anlage wird die Vorgehensweise der Bewertung näher erläutert. Zusammenfassend wird festgestellt, dass das vereinfachte Verfahren eine schnelle und sichere energetische Bewertung der genannten Anlagen erlaubt,, zu Präsenzwissen führt, die Haupteinflussgrößen aufzeigt und eine Anlagenbewertung ohne Gebäudebewertung gewährleistet. Das vereinfachte Verfahren wird im Frühjahr 2011 verfügbar sein. Es soll Bestandteil der DIN V 18599 werden, und die EnEV 2012 soll darauf Bezug nehmen.