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Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen
(2015)
Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
(2015)
A concept for a new generation of an integrated multi-functional biosensor/actuator system is developed, which is based on biomolecular logic principles. Such a system is expected to be able to detect multiple biochemical input signals simultaneously and in real-time and convert them into electrical output signals with logical operations such as OR, AND, etc. The system can be designed as a closed-loop drug release device triggered by an enzyme logic gate, while the release of the drug induced by the actuator at the required dosage and timing will be controlled by an additional drug sensor. Thus, the system could help to make an accurate and specific diagnosis. The presented concept is exemplarily demonstrated by using an enzyme logic gate based on a glucose/glucose oxidase system, a temperature-responsive hydrogel mimicking the actuator function and an insulin (drug) sensor. In this work, the results of functional testing of individual amperometric glucose and insulin sensors as well as an impedimetric sensor for the detection of the hydrogel swelling/shrinking are presented.
A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.
Manuelle Herstellung ist sozial fair, ökologisch nachhaltig und schafft qualitätsvolle Erzeugnisse! Vorbote für eine großformatige Rückkehr zum Handwerk und zur eigenhändigen Fertigung ist die Maker-Bewegung! – Solche Thesen begegnen uns gegenwärtig oft. Journalistische Texte, Filmdokumentationen, Werbung oder die Ästhetik von Produkten sind ihre Vehikel. Doch wie ist es um die Wiederbelebung des Handwerks tatsächlich bestellt? Und in welchem Verhältnis steht das Design – ein durch und durch industriebasiertes Berufsfeld – zu vorindustriellen Produktionsweisen? Diesen Fragen geht das vorliegende Buch ebenso auf den Grund wie der seit Beginn der Industrialisierung auftretenden Handwerksromantik. Es untersucht zudem, wie aktuelles Design die Sehnsucht nach dem Ursprünglichen mit formalen Kodes beantwortet und wie die visuellen Erscheinungsformen des Handgemachten ihre Wirkung freisetzen.
Thermal management in E-carsharing vehicles - preconditioning concepts of passenger compartments
(2015)
The issue of thermal management in electric vehicles includes the topics of drivetrain cooling and heating, interior temperature, vehicle body conditioning and safety. In addition to the need to ensure optimal thermal operating conditions of the drivetrain components (drive motor, battery and electrical components), thermal comfort must be provided for the passengers. Thermal comfort is defined as the feeling which expresses the satisfaction of the passengers with the ambient conditions in the compartment. The influencing factors on thermal comfort are the temperature and humidity as well as the speed of the indoor air and the clothing and the activity of the passengers, in addition to the thermal radiation and the temperatures of the interior surfaces. The generation and the maintenance of free visibility (ice- and moisture-free windows) count just as important as on-demand heating and cooling of the entire vehicle. A Carsharing climate concept of the innovative ec2go vehicle stipulates and allows for only seating areas used by passengers to be thermally conditioned in a close-to-body manner. To enable this, a particular feature has been added to the preconditioning of the Carsharing electric vehicle during the electric charging phase at the parking station.
Information and communication technology for integrated mobility concepts such as E-carsharing
(2015)
During the past decade attitude towards sharing things has changed extremely. Not just personal data is shared (e.g. in social networks) but also mobility. Together with the increased ecological awareness of the recent years, new mobility concepts have evolved. E-carsharing has become a symbol for these changes of attitude. The management of a shared car fleet, the energy management of electric mobility and the management of various carsharing users with individual likes and dislikes are just some of the major challenges of e-carsharing. Weaving it into integrated mobility concepts, this raises complexity even further. These challenges can only be overcome by an appropriate amount of well-shaped information available at the right place and time. In order to gather, process and share the required information, fleet cars have to be equipped with modern information and communication technology (ICT) and become so-called fully connected cars. Ensuring the usability of these ICT systems is another challenge that is often neglected, even though it is usability that makes carsharing comfortable, attractive and supports users’ new attitudes. By means of an integrated and consistent concept for human-machine interaction (HMI), the usability of such systems can be raised tremendously.