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Orthodontic treatments are concomitant with mechanical forces and thereby cause teeth movements. The applied forces are transmitted to the tooth root and the periodontal ligaments which is compressed on one side and tensed up on the other side. Indeed, strong forces can lead to tooth root resorption and the crown-to-tooth ratio is reduced with the potential for significant clinical impact. The cementum, which covers the tooth root, is a thin mineralized tissue of the periodontium that connects the periodontal ligament with the tooth and is build up by cementoblasts. The impact of tension and compression on these cells is investigated in several in vivo and in vitro studies demonstrating differences in protein expression and signaling pathways. In summary, osteogenic marker changes indicate that cyclic tensile forces support whereas static tension inhibits cementogenesis. Furthermore, cementogenesis experiences the same protein expression changes in static conditions as static tension, but cyclic compression leads to the exact opposite of cyclic tension. Consistent with marker expression changes, the singaling pathways of Wnt/ß-catenin and RANKL/OPG show that tissue compression leads to cementum degradation and tension forces to cementogenesis. However, the cementum, and in particular its cementoblasts, remain a research area which should be explored in more detail to understand the underlying mechanism of bone resorption and remodeling after orthodontic treatments.
This paper describes the potential for developing a digital twin of society- a dynamic model that can be used to observe, analyze, and predict the evolution of various societal aspects. Such a digital twin can help governmental agencies and policy makers in interpreting trends, understanding challenges, and making decisions regarding investments or policies necessary to support societal development and ensure future prosperity. The paper reviews related work regarding the digital twin paradigm and its applications. The paper presents a motivating case study- an analysis of opportunities and challenges faced by the German federal employment agency, Bundesagentur f¨ur Arbeit (BA), proposes solutions using digital twins, and describes initial proofs of concept for such solutions.
The Solar-Institut Jülich (SIJ) and the companies Hilger GmbH and Heliokon GmbH from Germany have developed a small-scale cost-effective heliostat, called “micro heliostat”. Micro heliostats can be deployed in small-scale concentrated solar power (CSP) plants to concentrate the sun's radiation for electricity generation, space or domestic water heating or industrial process heat. In contrast to conventional heliostats, the special feature of a micro heliostat is that it consists of dozens of parallel-moving, interconnected, rotatable mirror facets. The mirror facets array is fixed inside a box-shaped module and is protected from weathering and wind forces by a transparent glass cover. The choice of the building materials for the box, tracking mechanism and mirrors is largely dependent on the selected production process and the intended application of the micro heliostat. Special attention was paid to the material of the tracking mechanism as this has a direct influence on the accuracy of the micro heliostat. The choice of materials for the mirror support structure and the tracking mechanism is made in favor of plastic molded parts. A qualification assessment method has been developed by the SIJ in which a 3D laser scanner is used in combination with a coordinate measuring machine (CMM). For the validation of this assessment method, a single mirror facet was scanned and the slope deviation was computed.
Objective
This study assesses and quantifies impairment of postoperative magnetic resonance imaging (MRI) at 7 Tesla (T) after implantation of titanium cranial fixation plates (CFPs) for neurosurgical bone flap fixation.
Materials and methods
The study group comprised five patients who were intra-individually examined with 3 and 7 T MRI preoperatively and postoperatively (within 72 h/3 months) after implantation of CFPs. Acquired sequences included T₁-weighted magnetization-prepared rapid-acquisition gradient-echo (MPRAGE), T₂-weighted turbo-spin-echo (TSE) imaging, and susceptibility-weighted imaging (SWI). Two experienced neurosurgeons and a neuroradiologist rated image quality and the presence of artifacts in consensus reading.
Results
Minor artifacts occurred around the CFPs in MPRAGE and T2 TSE at both field strengths, with no significant differences between 3 and 7 T. In SWI, artifacts were accentuated in the early postoperative scans at both field strengths due to intracranial air and hemorrhagic remnants. After resorption, the brain tissue directly adjacent to skull bone could still be assessed. Image quality after 3 months was equal to the preoperative examinations at 3 and 7 T.
Conclusion
Image quality after CFP implantation was not significantly impaired in 7 T MRI, and artifacts were comparable to those in 3 T MRI.
Deammonification for nitrogen removal in municipal wastewater in temperate and cold climate zones is currently limited to the side stream of municipal wastewater treatment plants (MWWTP). This study developed a conceptual model of a mainstream deammonification plant, designed for 30,000 P.E., considering possible solutions corresponding to the challenging mainstream conditions in Germany. In addition, the energy-saving potential, nitrogen elimination performance and construction-related costs of mainstream deammonification were compared to a conventional plant model, having a single-stage activated sludge process with upstream denitrification. The results revealed that an additional treatment step by combining chemical precipitation and ultra-fine screening is advantageous prior the mainstream deammonification. Hereby chemical oxygen demand (COD) can be reduced by 80% so that the COD:N ratio can be reduced from 12 to 2.5. Laboratory experiments testing mainstream conditions of temperature (8–20°C), pH (6–9) and COD:N ratio (1–6) showed an achievable volumetric nitrogen removal rate (VNRR) of at least 50 gN/(m3∙d) for various deammonifying sludges from side stream deammonification systems in the state of North Rhine-Westphalia, Germany, where m3 denotes reactor volume. Assuming a retained Norganic content of 0.0035 kgNorg./(P.E.∙d) from the daily loads of N at carbon removal stage and a VNRR of 50 gN/(m3∙d) under mainstream conditions, a resident-specific reactor volume of 0.115 m3/(P.E.) is required for mainstream deammonification. This is in the same order of magnitude as the conventional activated sludge process, i.e., 0.173 m3/(P.E.) for an MWWTP of size class of 4. The conventional plant model yielded a total specific electricity demand of 35 kWh/(P.E.∙a) for the operation of the whole MWWTP and an energy recovery potential of 15.8 kWh/(P.E.∙a) through anaerobic digestion. In contrast, the developed mainstream deammonification model plant would require only a 21.5 kWh/(P.E.∙a) energy demand and result in 24 kWh/(P.E.∙a) energy recovery potential, enabling the mainstream deammonification model plant to be self-sufficient. The retrofitting costs for the implementation of mainstream deammonification in existing conventional MWWTPs are nearly negligible as the existing units like activated sludge reactors, aerators and monitoring technology are reusable. However, the mainstream deammonification must meet the performance requirement of VNRR of about 50 gN/(m3∙d) in this case.
The implementation of IO-Link in the automation industry has increased over the years. Its main advantage is it offers a digital point-to-point plugand-play interface for any type of device or application. This simplifies the communication between devices and increases productivity with its different features like self-parametrization and maintenance. However, its complete potential is not always used.
The aim of this paper is to create an Arduino based framework for the development of generic IO-Link devices and increase its implementation for rapid prototyping. By generating the IO device description file (IODD) from a graphical user interface, and further customizable options for the device application, the end-user can intuitively develop generic IO-Link devices. The peculiarity of this framework relies on its simplicity and abstraction which allows to implement any sensor functionality and virtually connect any type of device to an IO-Link master. This work consists of the general overview of the framework, the technical background of its development and a proof of concept which demonstrates the workflow for its implementation.
The recent amendment to the Ethernet physical layer known as the IEEE 802.3cg specification, allows to connect devices up to a distance of one kilometer and delivers a maximum of 60 watts of power over a twisted pair of wires. This new standard, also known as 10BASE-TIL, promises to overcome the limits of current physical layers used for field devices and bring them a step closer to Ethernet-based applications. The main advantage of 10BASE- TIL is that it can deliver power and data over the same line over a long distance, where traditional solutions (e.g., CAN, IO-Link, HART) fall short and cannot match its 10 Mbps bandwidth. Due to its recentness, IOBASE- TIL is still not integrated into field devices and it has been less than two years since silicon manufacturers released the first Ethernet-PHY chips. In this paper, we present a design proposal on how field devices could be integrated into a IOBASE-TIL smart switch that allows plug-and-play connectivity for sensors and actuators and is compliant with the Industry 4.0 vision. Instead of presenting a new field-level protocol for this work, we have decided to adopt the IO-Link specification which already includes a plug-and-play approach with features such as diagnosis and device configuration. The main objective of this work is to explore how field devices could be integrated into 10BASE-TIL Ethernet, its adaption with a well-known protocol, and its integration with Industry 4.0 technologies.
The development of protype applications with sensors and actuators in the automation industry requires tools that are independent of manufacturer, and are flexible enough to be modified or extended for any specific requirements. Currently, developing prototypes with industrial sensors and actuators is not straightforward. First of all, the exchange of information depends on the industrial protocol that these devices have. Second, a specific configuration and installation is done based on the hardware that is used, such as automation controllers or industrial gateways. This means that the development for a specific industrial protocol, highly depends on the hardware and the software that vendors provide. In this work we propose a rapid-prototyping framework based on Arduino to solve this problem. For this project we have focused to work with the IO-Link protocol. The framework consists of an Arduino shield that acts as the physical layer, and a software that implements the IO-Link Master protocol. The main advantage of such framework is that an application with industrial devices can be rapid-prototyped with ease as its vendor independent, open-source and can be ported easily to other Arduino compatible boards. In comparison, a typical approach requires proprietary hardware, is not easy to port to another system and is closed-source.
One central challenge for self-driving cars is a proper path-planning. Once a trajectory has been found, the next challenge is to accurately and safely follow the precalculated path. The model-predictive controller (MPC) is a common approach for the lateral control of autonomous vehicles. The MPC uses a vehicle dynamics model to predict the future states of the vehicle for a given prediction horizon. However, in order to achieve real-time path control, the computational load is usually large, which leads to short prediction horizons. To deal with the computational load, the control algorithm can be parallelized on the graphics processing unit (GPU). In contrast to the widely used stochastic methods, in this paper we propose a deterministic approach based on grid search. Our approach focuses on systematically discovering the search area with different levels of granularity. To achieve this, we split the optimization algorithm into multiple iterations. The best sequence of each iteration is then used as an initial solution to the next iteration. The granularity increases, resulting in smooth and predictable steering angle sequences. We present a novel GPU-based algorithm and show its accuracy and realtime abilities with a number of real-world experiments.
Visionsbild eines BMW AG internen Tools : Optimierung einer datenzentrierten Plattform der BMW AG
(2022)
Die BMW AG verfolgt mehrere Ansätze eine optimierte Effizienzsteigerung durch eigens entwickelte Softwaretools zu erreichen. Der Fokus hierbei liegt in der Ermöglichung einer datenzentrierten, nutzerorientierten und hochautomatisierten Fahrzeugentwicklung. Das eigen von der BMW AG entwickelte Software-Tool „Parts List“ dient als digitale Bauteilliste für Entwicklungsteams. Das Tool bündelt mehrere Datenbanken und stellt diese in Echtzeit zur Verfügung. Somit kann der manuelle Pflegeaufwand erheblich reduziert und eine Durchgängigkeit einer Vielzahl von Daten ermöglicht werden. Der Fokus der Abschlussarbeit liegt in der konzeptionellen und gestalterischen Optimierung des Tools. Dabei wird insbesondere der User Centered Design Prozess betrachtet, bei dem die Nutzer bzw. die Entwicklungsteams im Zentrum stehen.
A laser-enhanced solar sail is a solar sail that is not solely propelled by solar radiation but additionally by a laser beam that illuminates the sail. This way, the propulsive acceleration of the sail results from the combined action of the solar and the laser radiation pressure onto the sail. The potential source of the laser beam is a laser satellite that coverts solar power (in the inner solar system) or nuclear power (in the outer solar system) into laser power. Such a laser satellite (or many of them) can orbit anywhere in the solar system and its optimal orbit (or their optimal orbits) for a given mission is a subject for future research. This contribution provides the model for an ideal laser-enhanced solar sail and investigates how a laser can enhance the thrusting capability of such a sail. The term ”ideal” means that the solar sail is assumed to be perfectly reflecting and that the laser beam is assumed to have a constant areal power density over the whole sail area. Since a laser beam has a limited divergence, it can provide radiation pressure at much larger solar distances and increase the radiation pressure force into the desired direction. Therefore, laser-enhanced solar sails may make missions feasible, that would otherwise have prohibitively long flight times, e.g. rendezvous missions in the outer solar system. This contribution will also analyze exemplary mission scenarios and present optimial trajectories without laying too much emphasis on the design and operations of the laser satellites. If the mission studies conclude that laser-enhanced solar sails would have advantages with respect to ”traditional” solar sails, a detailed study of the laser satellites and the whole system architecture would be the second next step
The objective of this study is the establishment of a differential scanning calorimetry (DSC) based method for online analysis of the biodegradation of polymers in complex environments. Structural changes during biodegradation, such as an increase in brittleness or crystallinity, can be detected by carefully observing characteristic changes in DSC profiles. Until now, DSC profiles have not been used to draw quantitative conclusions about biodegradation. A new method is presented for quantifying the biodegradation using DSC data, whereby the results were validated using two reference methods.
The proposed method is applied to evaluate the biodegradation of three polymeric biomaterials: polyhydroxybutyrate (PHB), cellulose acetate (CA) and Organosolv lignin. The method is suitable for the precise quantification of the biodegradability of PHB. For CA and lignin, conclusions regarding their biodegradation can be drawn with lower resolutions. The proposed method is also able to quantify the biodegradation of blends or composite materials, which differentiates it from commonly used degradation detection methods.
Die stoffliche Nutzung von Lignin aus Bioraffinerien ist ein wichtiger Bestandteil für den Wertschöpfungsprozess von nachwachsenden, pflanzlichen Rohstoffen. Lignin zählt zu den wenigen erneuerbaren Quellen für phenolische Bestandteile, wird aber derzeit meist nur thermisch verwertet. Ziel dieses Forschungsvorhabens ist die Funktionalisierung von Lignin zur Verbesserung der Adhäsionseigenschaften. Als funktionelle Gruppe wird die aromatische Aminosäure L-DOPA verwendet, die charakteristisch für die Adhäsionskraft von Muscheln ist. Lignin ist ein geeignetes Stützgerüst, da es ein Polymer ist, das durch enzymkatalysierte Polymerisation gebildet wird. Essenziell für die Entwicklung ist ein besseres Verständnis über die Bildung von Lignin-Polymeren und deren verschiedene Eigenschaften. Um die Einflussfaktoren auf Kettenlänge und Polymerisationseffizienz zu untersuchen, werden zurzeit sowohl Ligninmodellkomponenten (LMK) als auch gelöstes Organosolv-Lignin verwendet. Laufende Untersuchungen werden zeigen, ob sich die enzymatische Polymerisationsreaktion auf ein gelöstes Ligninpolymer aus einem Organosolv-Aufschluss übertragen lässt.
Aufgrund von EU-Regularien und Umweltinitiativen wächst der Markt für nachhaltige und abbaubare Klebstoffe stetig. Organosolv (OS)-Lignin ist ein kommerziell wenig ertragreicher Nebenstrom der Lignocellulose-Bioraffinerie. Durch das "Nachahmen" der Adhäsionseigenschaften mit strukturverwandten Muschel-Aminosäuren soll OS-Lignin in einen starkes, vollständig biobasiertes Adhäsiv umgewandelt werden. Funktionsweisend für die Adhäsion des Muschelklebstoffes ist die Catecholgruppe der Aminosäure L-DOPA. Die laccase-katalysierte Polymerisationsreaktion von Lignin und L-DOPA ist schwierig zu kontrollieren, da L-DOPA eine Ringschlussreaktion eingeht. Stattdessen wurde eine zweistufige Reaktion mit einem Diamin als Ankermolekül etabliert. Die Catecholgruppe, die im zweiten Schritt enzymatisch an das Lignin-Amin gebunden wird, kann durch Komplexbildung mit Fe(III)-Ionen sowohl zur Adhäsion als auch zur Kohäsion des Klebstoffes beitragen. Der Lignin-Catechol-Klebstoff ist frei von petrochemischen Chemikalien und biologisch abbaubar. In ersten Stirnzugversuchen konnte eine Haftkraft von 0,3 MPa erreicht werden.
Entwicklung timingabhängiger Marketing Strategien in frühen Phasen des Produktentstehungsprozesses
(1995)
Couponing
(2003)
Messenger apps like WhatsApp or Telegram are an integral part of daily communication. Besides the various positive effects, those services extend the operating range of criminals. Open trading groups with many thousand participants emerged on Telegram. Law enforcement agencies monitor suspicious users in such chat rooms. This research shows that text analysis, based on natural language processing, facilitates this through a meaningful domain overview and detailed investigations. We crawled a corpus from such self-proclaimed black markets and annotated five attribute types products, money, payment methods, user names, and locations. Based on each message a user sends, we extract and group these attributes to build profiles. Then, we build features to cluster the profiles. Pretrained word vectors yield better unsupervised clustering results than current
state-of-the-art transformer models. The result is a semantically meaningful high-level overview of the user landscape of black market chatrooms. Additionally, the extracted structured information serves as a foundation for further data exploration, for example, the most active users or preferred payment methods.
Messenger apps like WhatsApp and Telegram are frequently used for everyday communication, but they can also be utilized as a platform for illegal activity. Telegram allows public groups with up to 200.000 participants. Criminals use these public groups for trading illegal commodities and services, which becomes a concern for law enforcement agencies, who manually monitor suspicious activity in these chat rooms. This research demonstrates how natural language processing (NLP) can assist in analyzing these chat rooms, providing an explorative overview of the domain and facilitating purposeful analyses of user behavior. We provide a publicly available corpus of annotated text messages with entities and relations from four self-proclaimed black market chat rooms. Our pipeline approach aggregates the extracted product attributes from user messages to profiles and uses these with their sold products as features for clustering. The extracted structured information is the foundation for further data exploration, such as identifying the top vendors or fine-granular price analyses. Our evaluation shows that pretrained word vectors perform better for unsupervised clustering than state-of-the-art transformer models, while the latter is still superior for sequence labeling.
Digital elevation models (DEMs), represent the three-dimensional terrain and are the basic input for numerical snow avalanche dynamics simulations. DEMs can be acquired using topographic maps or remote-sensing technologies, such as photogrammetry or lidar. Depending on the acquisition technique, different spatial resolutions and qualities are achieved. However, there is a lack of studies that investigate the sensitivity of snow avalanche simulation algorithms to the quality and resolution of DEMs. Here, we perform calculations using the numerical avalance dynamics model RAMMS, varying the quality and spatial resolution of the underlying DEMs, while holding the simulation parameters constant. We study both channelized and open-terrain avalanche tracks with variable roughness. To quantify the variance of these simulations, we use well-documented large-scale avalanche events from Davos, Switzerland (winter 2007/08), and from our large-scale avalanche test site, Valĺee de la Sionne (winter 2005/06). We find that the DEM resolution and quality is critical for modeled flow paths, run-out distances, deposits, velocities and impact pressures. Although a spatial resolution of ~25 m is sufficient for large-scale avalanche modeling, the DEM datasets must be checked carefully for anomalies and artifacts before using them for dynamics calculations.
Dieser Artikel befasst sich mit dem Investitionsdilemma in der Stromerzeugung, welches in unzureichend ausgestalteten liberalisierten Strommärkten zu einem gesamtwirtschaftlich unerwünscht geringen Niveau an Versorgungssicherheit führt. Die originären Ursachen im deutschen Strommarkt liegen in einer eingeschränkten Schadenersatzpflicht der Lieferanten im Falle eines kapazitätsbedingten Stromausfalls und in der zeitlichen Differenz zwischen letzter Handelsmöglichkeit und Lieferung. Letzteres verhindert ein jederzeitiges individuelles Glattstellen von unerwartet auftretenden Ein- bzw. Ausspeiseänderungen. Des Weiteren führen Faktoren wie die fehlende Partizipation der Endverbraucher am Großhandelsmarkt, die nur undifferenziert mögliche Abschaltung von Endverbrauchern oder time lags durch lange Bau- und Genehmigungszeiten von Erzeugungskapazitäten in Verbindung mit über lange Zeiträume nicht versicherbaren Risiken bezüglich Brennstoff-, CO2-Zertifikate- und Strompreisen zu einer Verschärfung der Problematik. Sinnvolle Lösungsansätze sind zum einen die Erhöhung der Intraday-Handelsliquidität zur Verbesserung der Markträumungsfunktion bis möglichst kurz vor Stromlieferung, was z. B. durch eine Förderung der Direktvermarktung Erneuerbarer Energien erreicht werden kann. Zum anderen trägt ein verstärkter Ausbau von smart metern bei Endverbrauchern zu einer höheren Versorgungssicherheit bei, da dies die Glättung von Lastspitzen und die Artikulation der tatsächlichen Zahlungsbereitschaft von Endverbrauchern am Großhandelsmarkt ermöglicht.
Netzsektoren und deren adäquate Regulierung sind ein sehr relevantes und aktuelles Thema. Dies gilt sowohl für die ökonomische Theorie, die sich sehr intensiv damit auseinandersetzt und in den letzten Jahrzehnten zahlreiche neue Erkenntnisse gewonnen hat. Es gilt ebenso für die Politik, in der Regulierungsfragen kontrovers diskutiert werden und dies nicht nur unter ökonomischen Gesichtspunkten. Es gilt selbstverständlich für die regulierten Unternehmen selbst, deren Tätigkeit durch die staatlichen Regulierungsvorgaben markant beeinflusst wird. Nicht nur die konkreten Inhalte der Regulierungsregime sowie die verbleibenden Freiheitsgrade in der Ausgestaltung sind von Bedeutung, sondern ebenso die Umsetzung durch die Regulierungsbehörden. All dies gilt für den Strommarkt und seinen regulatorischen Hintergrund in besonderer Weise. Die Entflechtung der Stromübertragungsnetze von der Stromproduktion und damit die Vorgaben für die Organisation der Wertschöpfungsketten in den Elektrizitätsunternehmen sind seit dem Beginn des europäischen Liberalisierungsprozesses der Strommärkte ein wichtiges und kontrovers diskutiertes Regulierungselement. Den Fokus bildet das vertikale Unbundling, das letztlich die Diskriminierung von Wettbewerbern durch Anbieter mit aggregierten Wertschöpfungsketten verhindern soll, indem diese gezwungen werden, ihren "Netzteil" anders zu organisieren oder zu verkaufen. Den Mitgliedsstaaten blieben Freiräume in der Ausgestaltung, die in Deutschland erst vor kurzem konkretisiert wurden, und die für die regulierten Unternehmen die Nutzung eines Wahlrechts beinhalten. Der wirtschaftspolitischen folgt nun eine unternehmerische Abwägungsentscheidung.
Zahlreiche Einflussfaktoren haben in den vergangenen Jahren das Gesicht der Elektrizitätsmärkte stark verändert. Hierzu zählen vor allem die Einführung der ökonomischen Gesetze des Wettbewerbsmarktes durch die Liberalisierung sowie die nun kostenpflichtige Berücksichtigung des bei der Stromerzeugung hervorgerufenen CO2-Ausstoßes durch die Einführung des europäischen Emissionshandelssystems (EUTS). Die Folgen dieses Veränderungsprozesses lassen sich auf Grund der langen Investitionszyklen im Kraftwerksbau bisher nur unvollständig überblicken. Dies ist insbesondere im Hinblick auf die Versorgungssicherheit als Teil des energiewirtschaftlichen Zieldreiecks des § 1 EnWG von großer Bedeutung. Dazu zählt insbesondere, ob die Versorgungssicherheit in Deutschland bei gegenwärtigem Marktdesign auch dauerhaft gewährleistet sein wird. Es stellt sich heraus, dass es im Bereich der Spitzenlastkraftwerke zu Investitionen in gesamtwirtschaftlich zu geringen Umfang kommen kann. Dieses Investitionsdilemma beruht auf einem externen Effekt, der durch die aktuelle Ausgestaltung des deutschen Schadenersatzrechtes entsteht. Hierdurch ist die sichere Stromversorgung in Zeiten hoher Last potenziell gefährdet. Um die Wirkungen des Investitionsdilemmas abzumildern oder ganz zu beseitigen sind verschiedene Investitionsanreize durch entsprechende Ausgestaltung des EUTS denkbar. Diese werden im Einzelnen analysiert.
Nach der Bundestagswahl am 27. September 2009 steht der Atomausstieg in Deutschland wieder ganz oben auf der politischen Agenda. Eine aktuelle Bestandsaufnahme aller ma\geblichen Argumente erscheint somit zwingend notwendig. Dabei sollte der Blickwinkel nicht national beschränkt bleiben, sondern vor allem der Einfluss der europäischen Dimension dieser Thematik miteinbezogen werden. Auf europäischer Ebene zeigt sich eine Position zu Gunsten der Kernenergie. Unter den 27 EU-Staaten findet gerade eine Renaissance der Atomkraft statt. Die drei europäischen Organe befürworten den umfangreichen Einsatz der Kernenergie als langfristigen Bestandteil des Energieträgermix. Deutschland gehört mit seinem Beschluss zum Atomausstieg einer Minderheit an. Als Teil eines immer stärker zusammen wachsenden und letztendlich vollständig integrierten europäischen Strommarktes wird Deutschland langfristig stets mit Atomstrom versorgt werden. Dies gilt losgelöst von dem Einsatz von Kernkraftwerken im Inland. Eine Abschaltung der Anlagen führt damit nicht zur Zielerreichung der Atomkraftgegner, sondern lediglich zu zusätzlichen energietechnischen Herausforderungen bei der Sicherstellung der deutschen Stromversorgung. Der deutsche Atomausstieg sollte aus diesem Grund von der neuen Bundesregierung zurück genommen werden.
Sensor positioning and thermal model for condition monitoring of pressure gas reservoirs in vehicles
(2018)
Sportvereine verlieren zunehmend Mitglieder. Grund dafür ist der wachsende Wunsch nach unabhängigen Trainingsmöglichkeiten. GYMLET bietet den Sportler:innen die Möglichkeit, ihre Fitness funktional, selbstorganisiert und unabhängig zu trainieren. Dabei kann durch den selbstbestimmten Trainingsort neben der körperlichen Fitness vor allem die Motivation zur sportlichen Aktivität und das Wohlbefinden gesteigert werden. Unterstützt wird das Trainingssystem durch eine App, welche den Sportler:innen neben Nutzungsmöglichkeiten als Coach und Trainingsplaner dient. Um diese Trainingsmöglichkeit an die Zielgruppe heranzutragen, ist eine Kampagnenstrategie aus zwei Phasen entstanden. In dieser sollen Postings und Clips über Instagram und Youtube veröffentlicht werden. Zusätzlich werden Zeitschriften und mögliche Kooperationen mit Therapeuten oder Freizeitunterkünften zur Veröffentlichung der Kampagne genutzt.
Der Wunsch nach Gesundheit und Individualisierung der eigenen Freizeit als Ausgleich zum Alltag ist heute in der Gesellschaft so ausgeprägt wie noch nie. Dabei sind die positiven Auswirkungen körperlicher Aktivität auf das Immunsystem, die Lebenserwartung und die Leistungsfähigkeit immer bekannter. Diese Abschlussarbeit greift die erkannte Entwicklung und den wachsenden Wunsch der Nutzenden nach individuellem Fitnesstraining im Freien auf. Das entstandene Outdoor-Trainingssystem „TREICK“ ermöglicht ein mobiles, orts- und zeitunabhängiges Training der eigenen Fitness. Durch „TREICK“ kann der Sportler physiologisch sinnvolle Eigengewichtsübungen in einer selbst gewählten Umgebung ausführen, wodurch das Wohlbefinden und damit die Gesundheit gefördert werden kann. Das System kann als Rucksack oder Fahrradtasche transportiert werden, wobei die Trainingsmatte als Verpackung dient.
Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan (distributed electric propulsion), leading to highly flexible dynamic systems that can exhibit aeroelastic instabilities. This paper introduces a validated methodology to investigate the aeroelastic instabilities of wing–propeller systems and to understand the dynamic mechanism leading to wing and whirl flutter and transition from one to the other. Factors such as nacelle positions along the wing span and chord and its propulsion system mounting stiffness are considered. Additionally, preliminary design guidelines are proposed for flutter-free wing–propeller systems applicable to novel aircraft designs. The study demonstrates how the critical speed of the wing–propeller systems is influenced by the mounting stiffness and propeller position. Weak mounting stiffnesses result in whirl flutter, while hard mounting stiffnesses lead to wing flutter. For the latter, the position of the propeller along the wing span may change the wing mode shapes and thus the flutter mechanism. Propeller positions closer to the wing tip enhance stability, but pusher configurations are more critical due to the mass distribution behind the elastic axis.
Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan. These highly flexible dynamic systems can exhibit uncommon aeroelastic instabilities, which should be carefully investigated to ensure safe operation. The interaction between the propeller and the wing is of particular importance. It is known that whirl flutter is stabilized by wing motion and wing aerodynamics. This paper investigates the effect of a propeller onto wing flutter as a function of span position and mounting stiffness between the propeller and wing. The analysis of a comparison between a tractor and pusher configuration has shown that the coupled system is more stable than the standalone wing for propeller positions near the wing tip for both configurations. The wing fluttermechanism is mostly affected by the mass of the propeller and the resulting change in eigenfrequencies of the wing. For very weak mounting stiffnesses, whirl flutter occurs, which was shown to be stabilized compared to a standalone propeller due to wing motion. On the other hand, the pusher configuration is, as to be expected, the more critical configuration due to the attached mass behind the elastic axis.
Today’s society is undergoing a paradigm shift driven by the megatrend of sustainability. This undeniably affects all areas of Western life. This paper aims to find out how the luxury industry is dealing with this change and what adjustments are made by the companies. For this purpose, interviews were conducted with managers from the luxury industry, in which they were asked about specific measures taken by their companies as well as trends in the industry. In a subsequent evaluation, the trends in the luxury industry were summarized for the areas of ecological, social, and economic sustainability. It was found that the area of environmental sustainability is significantly more focused than the other sub-areas. Furthermore, the need for a customer survey to validate the industry-based measures was identified.
Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3–12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.
A microfluidic chip integrating amperometric enzyme sensors for the detection of glucose, glutamate and glutamine in cell-culture fermentation processes has been developed. The enzymes glucose oxidase, glutamate oxidase and glutaminase were immobilized by means of cross-linking with glutaraldehyde on platinum thin-film electrodes integrated within a microfluidic channel. The biosensor chip was coupled to a flow-injection analysis system for electrochemical characterization of the sensors. The sensors have been characterized in terms of sensitivity, linear working range and detection limit. The sensitivity evaluated from the respective peak areas was 1.47, 3.68 and 0.28 μAs/mM for the glucose, glutamate and glutamine sensor, respectively. The calibration curves were linear up to a concentration of 20 mM glucose and glutamine and up to 10 mM for glutamate. The lower detection limit amounted to be 0.05 mM for the glucose and glutamate sensor, respectively, and 0.1 mM for the glutamine sensor. Experiments in cell-culture medium have demonstrated a good correlation between the glutamate, glutamine and glucose concentrations measured with the chip-based biosensors in a differential-mode and the commercially available instrumentation. The obtained results demonstrate the feasibility of the realized microfluidic biosensor chip for monitoring of bioprocesses.
Planar and three-dimensional (3D) interdigitated electrodes (IDE) with electrode digits separated by an insulating barrier of different heights were electrochemically characterized and compared in terms of their sensing properties. Due to the impact of the surface resistance, both types of IDE structures display a non-linear behavior in low-ionic strength solutions. The experimental data were fitted to an electrical equivalent circuit and interpreted taking into account the surface-charge-governed properties. The effect of a charged polyelectrolyte layer electrostatically assembled onto the sensor surface on the surface resistance in solutions with different KCl concentration is studied. In case of the same electrode footprint, 3D-IDEs show a larger cell constant and a higher sensitivity to molecular adsorption than that of planar IDEs. The obtained results demonstrate the potential of 3D-IDEs as a new transducer structure for a direct label-free sensing of charged molecules.
The conjunction of (bio-)chemical recognition elements with nanoscale biological building blocks such as virus particles is considered as a very promising strategy for the creation of biohybrids opening novel opportunities for label-free biosensing. This work presents a new approach for the development of biosensors using tobacco mosaic virus (TMV) nanotubes or coat proteins (CPs) as enzyme nanocarriers. Sensor chips combining an array of Pt electrodes loaded with glucose oxidase (GOD)-modified TMV nanotubes or CP aggregates were used for amperometric detection of glucose as a model system for the first time. The presence of TMV nanotubes or CPs on the sensor surface allows binding of a high amount of precisely positioned enzymes without substantial loss of their activity, and may also ensure accessibility of their active centers for analyte molecules. Specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CPs was achieved via bioaffinity binding. These layouts were tested in parallel with glucose sensors with adsorptively immobilized [SA]-GOD, as well as [SA]-GOD crosslinked with glutardialdehyde, and came out to exhibit superior sensor performance. The achieved results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for future applications in biosensorics and biochips.
A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier
(2016)
Reinigungsprozesse in der Lebensmittelindustrie. Entwicklung eines Demonstrators zur Überwachung
(2017)
3D-Imaging
(2009)
A concept for the analysis and optimal design of reinforced concrete structures is described. It is based on a nonlinear optimization algorithm and a finite element program for linear and nonlinear analysis of structures. With the aim of minimal cost design a two stage optimization using efficient gradient algorithm is developed. The optimization problems on global (structural) and local (crosssectional) level are formulated. A parallelization concept for solving the two stage optimization problem in minimal time is presented. Examples are included to illustrate the practical use and the effectively of the parallelization in the area of engineering design.
Die erdbebensichere Auslegung von erdverlegten Rohrleitungssystemen ist von wesentlicher Bedeutung zur Sicherstellung der Funktionalität der Versorgungsinfrastruktur nach einem Erdbebenereignis. Zur Vermeidung von Netzausfällen ist es erforderlich, die räumlich weit ausgedehnten Leitungssysteme mit geeigneten rechnerischen Modellen seismisch zu bemessen. Der vorliegende Beitrag behandelt die Beanspruchung von Rohrleitungssystemen durch seismische Welleneinwirkung und stellt geeignete Näherungsansätze und ein detailliertes Rechenmodell für seismische Leitungsanalysen vor. Mit den Ansätzen wird in Berechnungsbeispielen der Einfluss wesentlicher Parameter auf die seismisch induzierten Dehnungen in Rohrleitungssystemen untersucht.
Silos generally work as storage structures between supply and demand for various goods, and their structural safety has long been of interest to the civil engineering profession. This is especially true for dynamically loaded silos, e.g., in case of seismic excitation. Particularly thin-walled cylindrical silos are highly vulnerable to seismic induced pressures, which can cause critical buckling phenomena of the silo shell. The analysis of silos can be carried out in two different ways. In the first, the seismic loading is modeled through statically equivalent loads acting on the shell. Alternatively, a time history analysis might be carried out, in which nonlinear phenomena due to the filling as well as the interaction between the shell and the granular material are taken into account. The paper presents a comparison of these approaches. The model used for the nonlinear time history analysis considers the granular material by means of the intergranular strain approach for hypoplasticity theory. The interaction effects between the granular material and the shell is represented by contact elements. Additionally, soil–structure interaction effects are taken into account.
Mit finanzieller Unterstützung der Deutschen Gesellschaft für Mauerwerks- und Wohnungsbau e.V. (DGfM) und des Deutschen Instituts für Bautechnik in Berlin (DIBt) wurden zwei aufeinander aufbauende Forschungsvorhaben zur Verbesserung der seismischen Nachweise von Mauerwerksbauten in deutschen Erdbebengebieten durchgeführt. Zunächst wurde das seismische Verhalten von drei modernen unbewehrten Mauerwerksgebäuden in der Region Emilia Romagna in Italien während der Erdbebenserie im Jahr 2012 in Kooperation mit der Universität Pavia eingehend untersucht. Aufbauend auf den Erkenntnissen dieser Untersuchungen wurde ein verbessertes seismisches Bemessungskonzept für unbewehrte Mauerwerksbauten erarbeitet. Der Beitrag stellt die wesentlichen Ergebnisse dieser Forschungsarbeiten und deren Eingang in die Normung vor.