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Mathematik für Bauingenieure / K. J. Dienst. Fachhochsch. Aachen, Fachbereich 2, Bauingenieurwesen
(1985)
Dieringer, Matthias A. ; Renz, Wolfgang ; Lindel, Tomasz D. ; Seifert, Frank ; Frauenrath, Tobias ; von Knobelsdorf-Brenkenhoff, Florian ; Waiczies, Helmar ; Hoffmann, Werner ; Rieger, Jan ; Pfeiffer, Harald ; Ittermann, Bernd ; Schulz-Menger, Jeanette ; Niendorf, Thoralf
Purpose
To design and evaluate a four-channel cardiac transceiver coil array for functional cardiac imaging at 7T.
Materials and Methods
A four-element cardiac transceiver surface coil array was developed with two rectangular loops mounted on an anterior former and two rectangular loops on a posterior former. specific absorption rate (SAR) simulations were performed and a Burn:x-wiley:10531807:media:JMRI22451:tex2gif-stack-1 calibration method was applied prior to obtain 2D FLASH CINE (mSENSE, R = 2) images from nine healthy volunteers with a spatial resolution of up to 1 × 1 × 2.5 mm3.
Results
Tuning and matching was found to be better than 10 dB for all subjects. The decoupling (S21) was measured to be >18 dB between neighboring loops, >20 dB for opposite loops, and >30 dB for other loop combinations. SAR values were well within the limits provided by the IEC. Imaging provided clinically acceptable signal homogeneity with an excellent blood-myocardium contrast applying the Burn:x-wiley:10531807:media:JMRI22451:tex2gif-stack-2 calibration approach.
Conclusion
A four-channel cardiac transceiver coil array for 7T was built, allowing for cardiac imaging with clinically acceptable signal homogeneity and an excellent blood-myocardium contrast. Minor anatomic structures, such as pericardium, mitral, and tricuspid valves and their apparatus, as well as trabeculae, were accurately delineated.
4CH TX/RX Surface Coil for 7T: Design, Optimization and Application for Cardiac Function Imaging
(2010)
Dieringer, Matthias A. ; Renz, Wolfgang ; Lindel, Tomasz ; Seifert, Frank ; Frauenrath, Tobias ; Waiczies, Helmar ; von Knobelsdorff-Brenkhoff, Florian ; Santoro, Davide ; Hoffmann, Werner ; Ittermann, Bernd ; Schulz-Menger, Jeanette ; Niendorf, Thoralf
Practical impediments of ultra high field cardiovascular MR (CVMR) can be catalogued in exacerbated magnetic field and radio frequency (RF) inhomogeneities, susceptibility and off-resonance effects, conductive and dielectric effects in tissue, and RF power deposition constraints, which all bear the potential to spoil the benefit of CVMR at 7T. Therefore, a four element cardiac transceive surface coil array was developed. Cardiac imaging provided clinically acceptable signal homogeneity with an excellent blood myocardium contrast. Subtle anatomic structures, such as pericardium, mitral and tricuspid valves and their apparatus, papillary muscles, and trabecles were accurately delineated.
Um den immer komplexer werdenden Ansprüchen an Wohnraum gerecht zu werden, braucht es Möbel, die vielseitig und anpassbar sind. Koji ist ein Tisch, dessen Tischplatte unkompliziert in der Höhe verstellt werden und so in diversen Wohnsituationen eingesetzt werden kann. Er kann als Esstisch genauso genutzt werden wie als Beistell- oder Couchtisch.
Durch die Mechanik, die die Höhenverstellbarkeit ermöglicht, bekommt der Tisch einen verspielten, beinahe lebendigen Charakter, der zur Interaktion einlädt. Er ist mehr als ein stummer Begleiter des Alltags, sondern vielmehr Inspiration, seine Umgebung aktiv zu gestalten, um sie so für sich optimal einzurichten.
Sampling of dry surfaces for microorganisms is a main component of microbiological safety and is of critical importance in many fields including epidemiology, astrobiology as well as numerous branches of medical and food manufacturing. Aspects of biofilm formation, analysis and removal in aqueous solutions have been thoroughly discussed in literature. In contrast, microbial communities on air-exposed (dry) surfaces have received significantly less attention. Diverse surface sampling methods have been developed in order to address various surfaces and microbial groups, but they notoriously show poor repeatability, low recovery rates and suffer from lack of mutual consistency. Quantitative sampling for viable microorganisms represents a particular challenge, especially on porous and irregular surfaces. Therefore, it is essential to examine in depth the factors involved in microorganisms’ recovery efficiency and accuracy depending on the sampling technique used. Microbial colonization, retention and community composition on different dry surfaces are very complex and rely on numerous physicochemical and biological factors. This study is devoted to analyze and review the (a) physical phenomena and intermolecular forces relevant for microbiological surface sampling; (b) challenges and problems faced by existing sampling methods for viable microorganisms and (c) current directions of engineering and research aimed at improvement of quality and efficiency of microbiological surface sampling.
In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) synthesized by Medusomyces gisevii have been studied. The culture medium was composed of different initial concentrations of glucose or sucrose dissolved in 0.4% extract of plain green tea. Parameters of the culture media (titratable acidity, substrate conversion degree etc.) were monitored daily for 20 days of cultivation. The BC pellicles produced on different carbon sources were characterized in terms of biomass yield, crystallinity and morphology by field emission scanning electron microscopy (FE-SEM), atomic force microscopy and X-ray diffraction. Our results showed that Medusomyces gisevii had higher BC yields in media with sugar concentrations close to 10 g L−1 after a 18–20 days incubation period. Glucose in general lead to a higher BC yield (173 g L−1) compared to sucrose (163.5 g L−1). The BC crystallinity degree and surface roughness were higher in the samples synthetized from sucrose. Obtained FE-SEM micrographs show that the BC pellicles synthesized in the sucrose media contained densely packed tangles of cellulose fibrils whereas the BC produced in the glucose media displayed rather linear geometry of the BC fibrils without noticeable aggregates.
Digel, Ilya ; Akimbekov, Nuraly S. ; Turalieva, M. ; Mansurov, Z. ; Temiz Artmann, Aysegül ; Eshibaev, A. ; Zhubanova, A.
A melting probe equipped with autofluorescence-based detection system combined with a light scattering unit, and, optionally, with a microarray chip would be ideally suited to probe icy environments like Europa’s ice layer as well as the polar ice layers of Earth and Mars for recent and extinct live.
Mechanical stimulation of the cells resulted in evident changes in the cell morphology, protein composition and gene expression. Microscopically, additional formation of stress fibers accompanied by cell re-arrangements in a monolayer was observed. Also, significant activation of p53 gene was revealed as compared to control. Interestingly, the use of CellTech membrane coating induced cell death after mechanical stress had been applied. Such an effect was not detected when fibronectin had been used as an adhesion substrate.
With the variety of toothbrushes on the market, the question arises, which toothbrush is best suited to maintain oral health? This thematic review focuses first on plaque formation mechanisms and then on the plaque removal effectiveness of ultrasonic toothbrushes and their potential in preventing oral diseases like periodontitis, gingivitis, and caries. We overviewed the physical effects that occurred during brushing and tried to address the question of whether ultrasonic toothbrushes effectively reduced the microbial burden by increasing the hydrodynamic forces. The results of published studies show that electric toothbrushes, which combine ultrasonic and sonic (or acoustic and mechanic) actions, may have the most promising effect on good oral health. Existing ultrasonic/sonic toothbrush models do not significantly differ regarding the removal of dental biofilm and the reduction of gingival inflammation compared with other electrically powered toothbrushes, whereas the manual toothbrushes show a lower effectiveness.
Heterogeneous Composites on the Basis of Microbial Cells and Nanostructured Carbonized Sorbents
(2012)
Digel, Ilya ; Mansurov, Zulkhair ; Biisenbaev, Makhmut ; Savitskaya, Irina ; Kistaubaeva, Aida ; Akimbekov, Nuraly S. ; Zhubanova, Azhar
The fact that microorganisms prefer to grow on liquid/solid phase surfaces rather than in the surrounding aqueous phase was noticed long time ago [1]. Virtually any surface – animal, mineral, or vegetable – is a subject for microbial colonization and subsequent biofilm formation. It would be adequate to name just a few notorious examples on microbial colonization of contact lenses, ship hulls, petroleum pipelines, rocks in streams and all kinds of biomedical implants. The propensity of microorganisms to become surface-bound is so profound and ubiquitous that it vindicates the advantages for attached forms over their free-ranging counterparts [2]. Indeed, from ecological and evolutionary standpoints, for many microorganisms the surface-bound state means dwelling in nutritionally favorable, non-hostile environments [3]. Therefore, in most of natural and artificial ecosystems surface-associated microorganisms vastly outnumber organisms in suspension and often organize into complex communities with features that differ dramatically from those of free cells [4].
Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations
(2015)
Recently, SHARP corporation has developed the world’s first “Plasma Cluster Ions (PCI)” air purification technology, which uses plasma discharge to generate cluster ions. The new plasma cluster device releases into the air positive and negative ions, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. A lot of phenomenological tests of the PCI air purification technology on microbial cells have been conducted. And, in most cases, it has been shown that PCI demonstrate strongly pronounced killing effect. Although, the particular mechanisms of PCI action are still not evident. We studied variations in resistance to PCI among gram-positive airborne microorganisms, as well as some dose-dependent, spatial, cultural and biochemical properties of PCI action in respect of Staphylococcus spp, Enterococcus spp, Micrococcus spp.
Recently, the SHARP Corporation, Japan, has developed the world’s first "Plasma Cluster Ions (PCI)" air purification technology using plasma discharge to generate cluster ions. The new plasma cluster device releases positive and negative ions into the air, which are able to decompose and deactivate harmful airborne substances by chemical reactions. Because cluster ions consist of positive and negative ions that normally exist in the natural world, they are completely harmless and safe to humans. The amount of ozone generated by cluster ions is less than 0.01 ppm, which is significantly less than the 0.05-ppm standard for industrial operations and consumer electronics. This amount, thus, has no harming effects whatsoever on the human body. But particular properties and chemical processes in PCI treatment are still under study. It has been shown that PCI in most cases show strongly pronounced irreversible killing effects in respect of airborne microflora due to free-radical induced reactions and can be considered as a potent technology to disinfect both home, medical and industrial appliances.
Summary and Conclusions PCIs were clearly effective in terms of their antibacterial effects with the strains tested. This efficacy increased with the time the bacteries were exposed to PCIs. The bactericidal action has proved to be irreversible. PCIs were significantly less effective in shadowed areas. PCI exposure caused multiple protein damages as observed in SDS PAGE studies. There was no single but multiple molecular mechanism causing the bacterial death.
Recently, SHARP corporation has developed the world’s first "Plasma Cluster Ions® (PCI)" air purification technology, which uses plasma discharge to generate cluster ions. The new Plasma Cluster Device releases positive and negative ions into the air, which are harmless to humans and are able to decompose and deactivate airborne substances by chemical reactions. In the past, phenomenological tests on the efficacy of the PCI air purification technology on microbial cells have been conducted. In most cases, it has been shown that PCI demonstrated strongly pronounced killing effects on microorganisms. However, the particular mechanisms of PCI action still have to be uncovered.
Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids
(2018)
Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel ‘suspension depletion’ approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10–12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.
Weak Representation of the Cumulative Hazard Function under Semiparametric Random Censorship Models
(2001)
We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan–Meier estimator.
In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model.
Based on an identifying Volterra type integral equation for randomly right censored observations from a lifetime distribution function F, we solve the corresponding estimating equation by an explicit and implicit Euler scheme. While the first approach results in some known estimators, the second one produces new semi-parametric and pre-smoothed Kaplan–Meier estimators which are real distribution functions rather than sub-distribution functions as the former ones are. This property of the new estimators is particular useful if one wants to estimate the expected lifetime restricted to the support of the observation time.
Specifically, we focus on estimation under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. We show that some estimated linear functionals which are based on the new semi-parametric estimator are strong consistent, asymptotically normal, and efficient under SRCM. In a small simulation study, the performance of the new estimator is illustrated under moderate sample sizes. Finally, we apply the new estimator to a well-known real dataset.
This book provides a compact introduction to the bootstrap method. In addition to classical results on point estimation and test theory, multivariate linear regression models and generalized linear models are covered in detail. Special attention is given to the use of bootstrap procedures to perform goodness-of-fit tests to validate model or distributional assumptions. In some cases, new methods are presented here for the first time.
The text is motivated by practical examples and the implementations of the corresponding algorithms are always given directly in R in a comprehensible form. Overall, R is given great importance throughout. Each chapter includes a section of exercises and, for the more mathematically inclined readers, concludes with rigorous proofs. The intended audience is graduate students who already have a prior knowledge of probability theory and mathematical statistics.
Dilger, Klaus ; Mund, Frank ; Dilthey, Ulrich ; Schleser, Markus ; Raupach, Michael ; Walk-Lauffer, Bernd
Composite improvement of textile reinforced concrete by polymeric impregnation of the textiles
(2006)
Application of polymers in textile reinforced concrete : from the interface to construction elements
(2006)
With the many achievements of Machine Learning in the past years, it is likely that the sub-area of Deep Learning will continue to deliver major technological breakthroughs [1]. In order to achieve best results, it is important to know the various different Deep Learning frameworks and their respective properties. This paper provides a comparative overview of some of the most popular frameworks. First, the comparison methods and criteria are introduced and described with a focus on computer vision applications: Features and Uses are examined by evaluating papers and articles, Adoption and Popularity is determined by analyzing a data science study. Then, the frameworks TensorFlow, Keras, PyTorch and Caffe are compared based on the previously described criteria to highlight properties and differences. Advantages and disadvantages are compared, enabling researchers and developers to choose a framework according to their specific needs.
A nonparametric goodness-of-fit test for random variables with values in a separable Hilbert space is investigated. To verify the null hypothesis that the data come from a specific distribution, an integral type test based on a Cramér-von-Mises statistic is suggested. The convergence in distribution of the test statistic under the null hypothesis is proved and the test's consistency is concluded. Moreover, properties under local alternatives are discussed. Applications are given for data of huge but finite dimension and for functional data in infinite dimensional spaces. A general approach enables the treatment of incomplete data. In simulation studies the test competes with alternative proposals.
This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cramér–von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices.
Dobbertin, Matthias ; Eilmann, Britta ; Bleuler, Peter ; Giuggiola, Arnaud ; Graf Pannatier, Elisabeth ; Landolt, Werner ; Schleppi, Patrick ; Rigling, Andreas
In Valais, Switzerland, Scots pines (Pinus sylvestris L.) are declining, mainly following drought. To assess the impact of drought on tree growth and survival, an irrigation experiment was initiated in 2003 in a mature pine forest, approximately doubling the annual precipitation. Tree crown transparency (lack of foliage) and leaf area index (LAI) were annually assessed. Seven irrigated and six control trees were felled in 2006, and needles, stem discs and branches were taken for growth analysis. Irrigation in 2004 and 2005, both with below-average precipitation, increased needle size, area and mass, stem growth and, with a 1-year delay, shoot length. This led to a relative decrease in tree crown transparency (−14%) and to an increase in stand LAI (+20%). Irrigation increased needle length by 70%, shoot length by 100% and ring width by 120%, regardless of crown transparency. Crown transparency correlated positively with mean needle size, shoot length and ring width and negatively with specific leaf area. Trees with high crown transparency (low growth, short needles) experienced similar increases in needle mass and growth with irrigation than trees with low transparency (high growth, long needles), indicating that seemingly declining trees were able to ‘recover’ when water supply became sufficient. A simple drought index before and during the irrigation explained most of the variation found in the parameters for both irrigated and control trees.
Dobischat, Rolf ; Witt, Gerd ; Eich, Dieter ; Marschall, Herbert ; Thurn, Laura ; Kunkel, Maximilian ; Richter, Alina ; Gebhardt, Andreas
Elektronische Musik umgibt uns alle. Der Einfluss elektronischer Musikproduktion auf moderne Popularmusik ist nicht von der Hand zu weisen und ihre Produktionstechniken für heutige Standards unverzichtbar. Über die Jahre ihrer Entwicklung und den dabei entstandenen Musikrichtungen verschwanden die individuellen Charakteristika der verschiedenen Subgenres allerdings oft einfach unter der Sammelbezeichnung elektronischer Musik.
»Electrovisuals« stellt die auditiven Eigenschaften elektronischer Musik in Form von klaren Infografiken dar und sorgt damit für ein besseres Verständnis von Rhythmus und Struktur der Songs. Die verschiedenen Subgenres werden multimedial inszeniert und einander gegenübergestellt, um Ähnlichkeiten und Unterschiede zu betonen.
Mithilfe seiner Aufbereitung stellt das Projekt die hohe Diversität elektronischer Musik heraus und bereitet sie eindrucksvoll und greifbar auf.
Damit sich Kinder in einer zunehmend digitalisierten Welt zurechtfinden können, ist die Schulung von Medienkompetenz unerlässlich. Als Digital-Analog-Hybrid-Game ermöglicht „Einmal Gezheim und zurück“ die spielerische Auseinandersetzung mit verschiedenen Informationsquellen. Zum Lösen der integrierten Rätsel ist der Einsatz der beiliegenden Print-Komponenten erforderlich, sodass die Spielenden automatisch Bildschirmpausen einlegen, um sich mit einem analogen Recherche-Medium zu beschäftigen. Die Handlung wurde speziell für das Projekt konzipiert: Im Zentrum der Mystery-Erzählung stehen die 13-jährige Britta und ihr Nachbar Herr Erdmann, der 1973 spurlos verschwindet. Mithilfe der Notizen des Verschollenen, die im gedruckten Teil des Spiels zu finden sind, lösen die Spielenden in einem spannenden Point-and-Click-Adventure das Rätsel um die fiktive Stadt Gezheim, schwarze Löcher und ein vergessenes Alienvolk...
Doll, T. ; Scharnagl, K. ; Winter, R. ; Bögner, M. ; Eisele, I. ; Ostrik, B. ; Schöning, Michael Josef
Seit Jahrhunderten tragen Hebammen die Verantwortung für neues Leben und geben ihre Erfahrungen und ihr Können weiter. Trotz dieser ehrwürdigen Aufgabe gehören sie zu einer kleinen Berufsgruppe, die viel zu oft unterschätzt, überlastet und unterbezahlt wird. Sie sind Begleiter*innen in einer der sensibelsten und emotionalsten Zeiten des Lebens. Die Unterstützung einer Hebamme gewährleistet Aufklärung und Beistand während der Schwangerschaft, der Geburt und der Zeit im Wochenbett.
Das Projekt »Die Hebamme« ist ein Berufsportrait. Die Arbeit gibt Einblicke in die Tätigkeit und seine verschiedenen Bereiche und erzählt dabei hauptsächlich in Bildern. Zusätzlich berichten Hebammen aus unterschiedlichen Blickwinkeln über ihre Arbeit. Dieses Portrait stellt die Realtität der Arbeit dar und soll die Bedeutung der Tätigkeit näher bringen.
ADIE : Keramische Fassaden- und Wandverkleidung - Funktion und Wirkung von Schönheit im Design
(2023)
„ADIE“ ist eine Produktfamilie von Keramikplatten und Fliesen mit dreidimensionaler Oberfläche, welche durch Form und Farbe Schönheit zum Ausdruck bringen. Sie sind sowohl im Kontext der Architektur als Fassadenverkleidung anwendbar als auch im Innenbereich als Wandverkleidung. Die Fähigkeit von Schönheit, unsere Umgebung zu transformieren, nimmt eine leitende Rolle in dieser Arbeit ein. Als Inspirationsquelle für die Entwürfe dienten Dinge, die dem allgemeinen Schönheitsempfinden entsprechen: Wasser, Blüten, der Himmel und andere Naturphänomene. Diese wurden abstrahiert, in Reliefs übersetzt und in drei unterschiedliche Module weiterentwickelt. Sie sind konzeptionell frei skalierbar und wurden in Kleinserie im Gussverfahren prototypisiert. Mit „ADIE“ sollte auf die Funktion von Schönheit im Design Bezug genommen werden und etwas entstehen, das einfach „nur“ schön ist.
Donner, Ralf ; Rabel, Matthias ; Scholl, Ingrid ; Ferrein, Alexander ; Donner, Marc ; Geier, Andreas ; John, André ; Köhler, Christian ; Varga, Sebastian
Doorschodt, B. M. ; Schreinemachers, M. C. J. M. ; Behbahani, Mehdi ; Florquin, S. ; Weis, J. ; Staat, Manfred ; Tolba, R. H.
Dass der Stress im Krankenhaus eine Belastung für das Klinikpersonal darstellt, ist eine allseits bekannte Tatsache. Das liegt an dem anstrengenden Klinikalltag, welcher die Mitarbeiter:innen auf Belastungsprobe stellt. Lange Dienste und Überstunden, wenig Pausen und hohe Arbeitsverdichtung, Nacht- und Schichtdienst, zudem auch die aufwendige Dokumentation und ̈Bürokratie. Timewise behandelt die Thematik der Dienstplanerstellung im Krankenhaus unter der Berücksichtigung der psychischen und physischen Gesundheit des Klinikpersonals im Nacht- und Schichtdienst. Essenzielle Funktionen sind kürzere Kommunikationswege und eine gute Übersicht über den Soll-Ist-Abgleich inklusive Überstunden, Minusstunden, Abwesenheiten und den monatlichen Lohn. Der einfache Schichttausch und die Option der Berücksichtigung individueller Präferenzen und Wünsche ermöglicht es dem Personal, die Arbeit und das private Leben besser miteinander vereinen zu können, was sich positiv auf die Arbeitszufriedenheit auswirkt.