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„550 nm“ befasst sich mit dem physiologischen Farbwechsel von Tieren. Einige Fische, Amphibien und Reptilien – wie beispielsweise das Chamäleon oder der Tintenfisch – können ihre Körperfarbe schnell wechseln. Unsere Natur leidet unter Kriegen und dem Klimawandel und verliert dadurch ihre Schönheit. Diese zeichnet sich vor allem durch die beachtliche Diversität der Körperfärbung von Tieren aus. Die Funktionen erstrecken sich über Tarnung, Auflauern oder Warnung bis hin zu einer Werbefärbung. Nicht nur Tiere nutzen Farbe als Ausdrucks- und Kommunikationsmittel. Auch Designer*innen bedienen sich an Farben, um Stimmungen zu vermitteln oder um Aufmerksamkeit und Individualität zu generieren. In „550 nm“ wird das Phänomen des Farbwechsels durch Illustrationen visualisiert und soll als Inspiration für Designinnovationen dienen.
In modernen Fahrzeugkarosserien der Großserie kommen zunehmend Materialmischbauweisen zur Anwendung. In Zusammenarbeit der Daimler AG, der Tower Automotive Holding GmbH, der Imperia GmbH sowie der Partnerunternehmen KSM Castings GmbH und Schaufler Tooling GmbH & Co. KG wird das Leichtbaupotenzial von Aluminiumverbundguss-Stahlblech-Hybriden am Beispiel des vorderen Dachquerträgers des Mercedes-Benz Viano/Vito ausführlich untersucht.
In modernen Fahrzeugkarosserien der Großserie kommen zunehmend Materialmischbauweisen
zur Anwendung. In Zusammenarbeit der Daimler AG, der Tower Automotive Holding
GmbH, der Imperia GmbH sowie der Partnerunternehmen KSM Castings GmbH und Schaufler
Tooling GmbH & Co. KG wird das Leichtbaupotenzial von Stahlblech-AluminiumverbundgussHybriden
am Beispiel des vorderen Dachquerträgers des Mercedes-Benz Viano/Vito ausführlich
untersucht.
The construction of a statistical test is investigated which is based only on “reliability” and “precision” as quality criteria. The reliability of a statistical test is quantifiedin a straightforward way by the probability that the decision of the test is correct. However, the quantification of the precision of a statistical test is not at all evident. Thereforethe paper presents and discusses several approaches. Moreover the distinction of “nullhypothesis” and “alternative hypothesis” is not necessary any longer.
While plate fixation of proximal ulna fractures might lead to superior clinical results compared to tension band wiring, regular plates represent an established risk factor for wound complications. The olecranon double plates (Medartis, Basel, CH) might decrease complications related to the osteosynthesis because of their low profile and better anatomical fit. This study aimed to evaluate the biomechanical performance and clinical results of the olecranon double plates.
Wedrowski, M. ; Bruyndonckx, P. ; Tavernier, S. ; Zhi, L. ; Dang, J. ; Mendes, P. R. ; Perez, J. M. ; Ziemons, Karl
The monolithic scintillator block approach for gamma detection in the Positron Emission Tomography (PET) avoids estimating Depth of Interaction (DOI), reduces dead zones in detector and diminishes costs of detector production. Neural Networks (NN) are very efficient to determine the entrance point of a gamma incident on a scintillator block. This paper presents results on the robustness of the spatial resolution as a function of the random fraction in the data, temperature and HV fluctuations. This is important when implementing the method in a real scanner. Measurements were done with two Hamamatsu S8550 APD arrays, glued on a 20 Ã 20 Ã 10 mm3 monolithic LSO crystal block.
Weckesser, Matthias ; Hufnagel, Andreas ; Ziemons, Karl ; Grießmeier, Martin ; Sonnenberg, Frank ; Hackländer, Thomas ; Langen, Karl-J. ; Holschbach, Markus ; Elger, Christian E. ; Müller-Gärtner, Hans-W.
Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.
Weckesser, Martin ; Grießmeier, Martin ; Schmidt, Daniela ; Sonnenberg, Frank ; Ziemons, Karl ; Kemna, Lars ; Holschbach, Marcus ; Langen, Karl-J. ; Müller-Gärtner, Hans-W.
Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.
Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling
(2019)
Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling
(2015)
Manufacturing process simulation enables the evaluation and improvement of autoclave mold concepts early in the design phase. To achieve a high part quality at low cycle times, the thermal behavior of the autoclave mold can be investigated by means of simulations. Most challenging for such a simulation is the generation of necessary boundary conditions. Heat-up and temperature distribution in an autoclave mold are governed by flow phenomena, tooling material and shape, position within the autoclave, and the chosen autoclave cycle. This paper identifies and summarizes the most important factors influencing mold heat-up and how they can be introduced into a thermal simulation. Thermal measurements are used to quantify the impact of the various parameters. Finally, the gained knowledge is applied to develop a semi-empirical approach for boundary condition estimation that enables a simple and fast thermal simulation of the autoclave curing process with reasonably high accuracy for tooling optimization.
Weber, S. ; Terstegge, Andreas ; Halling, H. ; Herzog, H. ; Reinartz, R. ; Reinhart, P. ; Rongen, F. ; Müller-Gärtner, H.-W.
Weber, S. ; Terstegge, Andreas ; Engels, R. ; Herzog, H. ; Reinartz, R. ; Reinhart, P. ; Rongen, F. ; Müller-Gärtner, H. W. ; Halling, H.
Weber, Pascale ; Rigling, Andreas ; Eilmann, Britta ; Mayer, Phillip ; Wohlgemuth, Thomas ; Dobbertin, Matthias
Die Pflanzenvielfalt der Erde steht im Fokus aller Aktivitäten am Botanischen Garten und Botanischen Museum Berlin (BGBM). Umfangreiche wissenschaftliche Sammlungen bilden zusammen mit den historischen Garten- und Gewächshausanlagen, dem Museum und einer modernen Forschungsinfrastruktur die Grundlage für die dortige Arbeit. Darüber hinaus trägt das BGBM mit seinen Forschungs- und Entwicklungsprojekten zu nationalen und internationalen Biodiversitätsprogrammen bei. Umso wichtiger ist es, der Einrichtung ein klares und modernes Auftreten zu geben. Das neue Erscheinungsbild lässt Garten und Museum durch eine rahmende Typografie zu einer Einheit werden und kommuniziert so auch gleichzeitig das Leitbild der Einrichtung, als „Schaufenster in die Pflanzenwelt“ zu dienen. Es positioniert das BGBM zum einen als wissenschaftliche Institution und zum anderen als farbenfrohes Ausflugsziel und Erholungsort.
Dieser Beitrag beschreibt die herkömmlichen Maßnahmen wie die Kapazitätsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die Dämpfungserhöhung der Struktur mittels Inter-Story-Dämpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Ergänzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. Für die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Berücksichtigung der wesentlichen Nichtlinearitäten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, Dämpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, ökonomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt.
Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
(2015)
Warerkar, Shashikant ; Schmitz, Stefan ; Göttsche, Joachim ; Hoffschmidt, Bernhard ; Reißel, Martin ; Tamme, Rainer
Warerkar, Shashikant ; Schmitz, Stefan ; Göttsche, Joachim ; Hoffschmidt, Bernhard ; Reißel, Martin ; Tamme, Rainer
Characterizing volcanic ash elements from the 2015 eruptions of bromo and raung volcanoes, Indonesia
(2020)
Wardoyo, Arinto Y.P. ; Noor, Johan A.E. ; Elbers, Gereon ; Schmitz, Sandra ; Flaig, Sascha T. ; Budianto, Arif
The volcanic eruptions of Mt. Bromo and Mt. Raung in East Java, Indonesia, in 2015 perturbed volcanic materials and affected surface-layer air quality at surrounding locations. During the episodes, the volcanic ash from the eruptions influenced visibility, traffic accidents, flight schedules, and human health. In this research, the volcanic ash particles were collected and characterized by relying on the detail of physical observation. We performed an assessment of the volcanic ash elements to characterize the volcanic ash using two different methods which are aqua regia extracts followed by MP-AES and XRF laboratory test of bulk samples. The analysis results showed that the volcanic ash was mixed of many materials, such as Al, Si, P, K, Ca, Ti, V, Cr, Mn, Fe, Ni, and others. Fe, Si, Ca, and Al were found as the major elements, while the others were the trace elements Ba, Cr, Cu, Mn, P, Mn, Ni, Zn, Sb, Sr, and V with the minor concentrations. XRF analyses showed that Fe dominated the elements of the volcanic ash. The XRF analysis showed that Fe was at 35.40% in Bromo and 43.00% in Raung of the detected elements in bulk material. The results of aqua regia extracts analyzed by MP-AES were 1.80% and 1.70% of Fe element for Bromo and Raung volcanoes, respectively.
The composition and physiochemical properties of aquatic-phase natural organic matter (NOM) are most important problems for both environmental studies and water industry. Laser desorption/ionization (LDI) mass spectrometry facilitated successful examinations of NOM, as humic and fulvic acids in NOM are readily ionized by the nitrogen laser. In this study, hydrophobic NOMs (HPO NOMs) from river, reservoir and waste water were characterized by this technique. The effect of analytical variables like concentration, solvent composition and laser energy was investigated. The exact masses of small molecular NOM moieties in the range of 200–1200 m/z were determined in reflectron mode. In addition, spectra of post-source-decay experiments in this range showed that some compounds from different natural NOMs had the same fragmental ions. In the large mass range of 1200–15 000 Da, macromolecules and their aggregates were found in HPO NOMs from natural waters. Highly humic HPO exhibited mass peaks larger than 8000 Da. On the other hand, the waste water and reservoir water mainly had relatively smaller molecules of about 2000 Da. The LDI-MS measurements indicated that highly humic river waters were able to form large aggregates and membrane foulants, while the HPO NOMs from waste water and reservoir water were unlikely to form large aggregates. Copyright © 2014 John Wiley & Sons, Ltd.
Bachelorzeit
(2023)
Die Bachelorarbeit behandelt die Konzeption und Produktion der Sendung "Bachelorzeit". Ziel ist es, eine innovative Plattform für junge Zuschauer:innen zu schaffen und Einblicke in das Leben und die Themen der Stadt Aachen zu geben. Die Arbeit umfasst den gesamten Produktionsprozess inklusive der Einbindung der Zuschauer:innen und der visuellen Gestaltung. Die erfolgreiche Umsetzung ermöglicht eine ansprechende und nahbare Atmosphäre für ein jüngeres Publikum.
Aim of the AXON2 project (Adaptive Expert System for Object Recogniton using Neuml Networks) is the development of an object recognition system (ORS) capable of recognizing isolated 3d objects from arbitrary views. Commonly, classification is based on a single feature extracted from the original image. Here we present an architecture adapted from the Mixtures of Eaqerts algorithm which uses multiple neuml networks to integmte different features. During tmining each neural network specializes in a subset of objects or object views appropriate to the properties of the corresponding feature space. In recognition mode the system dynamically chooses the most relevant features and combines them with maximum eficiency. The remaining less relevant features arz not computed and do therefore not decelerate the-recognition process. Thus, the algorithm is well suited for ml-time applications.
Walk-Lauffer, Bernd ; Raupach, Michael ; Dilger, Klaus ; Böhm, Stefan ; Mundt, F. ; Dilthey, Ulrich ; Schleser, Markus
Werkstatt voller Historie
(2023)
Das Buch „Werkstatt voller Historie“ gibt einen Einblick in das Handwerk der Restaurierung und Konservierung. Wir leben in einer Gesellschaft, die von Konsum und schneller Verfügbarkeit geprägt ist. Produkte werden in Massen produziert, genutzt und oft schon nach kurzer Zeit wieder weggeworfen. Durch diese Mentalität der Wegwerfgesellschaft werden die Ressourcen unserer Erde erschöpft, und Umweltprobleme werden immer größer. Deshalb ist es wichtig, sich intensiv mit der Bewahrung von Kulturgut auseinanderzusetzen. Durch die Verwendung von Illustrationen und visuellen Darstellungen erleichtert das Buch die Kommunikation. Dadurch kann der Restaurierungsprozess einfacher verstanden werden. Mit dem Projekt soll das Interesse geweckt und über die Grundlagen und Herausforderungen der Restaurierung aufgeklärt werden.
Waldvogel, Janice ; Ritzmann, Ramona ; Freyler, Kathrin ; Helm, Michael ; Monti, Elena ; Albracht, Kirsten ; Stäudle, Benjamin ; Gollhofer, Albert ; Narici, Marco
Stretch-shortening type actions are characterized by lengthening of the pre-activated muscle-tendon unit (MTU) in the eccentric phase immediately followed by muscle shortening. Under 1 g, pre-activity before and muscle activity after ground contact, scale muscle stiffness, which is crucial for the recoil properties of the MTU in the subsequent push-off. This study aimed to examine the neuro-mechanical coupling of the stretch-shortening cycle in response to gravity levels ranging from 0.1 to 2 g. During parabolic flights, 17 subjects performed drop jumps while electromyography (EMG) of the lower limb muscles was combined with ultrasound images of the gastrocnemius medialis, 2D kinematics and kinetics to depict changes in energy management and performance. Neuro-mechanical coupling in 1 g was characterized by high magnitudes of pre-activity and eccentric muscle activity allowing an isometric muscle behavior during ground contact. EMG during pre-activity and the concentric phase systematically increased from 0.1 to 1 g. Below 1 g the EMG in the eccentric phase was diminished, leading to muscle lengthening and reduced MTU stretches. Kinetic energy at take-off and performance were decreased compared to 1 g. Above 1 g, reduced EMG in the eccentric phase was accompanied by large MTU and muscle stretch, increased joint flexion amplitudes, energy loss and reduced performance. The energy outcome function established by linear mixed model reveals that the central nervous system regulates the extensor muscles phase- and load-specifically. In conclusion, neuro-mechanical coupling appears to be optimized in 1 g. Below 1 g, the energy outcome is compromised by reduced muscle stiffness. Above 1 g, loading progressively induces muscle lengthening, thus facilitating energy dissipation.
Waldvogel, Janice ; Freyler, Kathrin ; Helm, Michael ; Monti, Elena ; Stäudle, Benjamin ; Gollhofer, Albert ; Narici, Marco V. ; Ritzmann, Ramona ; Albracht, Kirsten
This study evaluates neuromechanical control and muscle-tendon interaction during energy storage and dissipation tasks in hypergravity. During parabolic flights, while 17 subjects performed drop jumps (DJs) and drop landings (DLs), electromyography (EMG) of the lower limb muscles was combined with in vivo fascicle dynamics of the gastrocnemius medialis, two-dimensional (2D) kinematics, and kinetics to measure and analyze changes in energy management. Comparisons were made between movement modalities executed in hypergravity (1.8 G) and gravity on ground (1 G). In 1.8 G, ankle dorsiflexion, knee joint flexion, and vertical center of mass (COM) displacement are lower in DJs than in DLs; within each movement modality, joint flexion amplitudes and COM displacement demonstrate higher values in 1.8 G than in 1 G. Concomitantly, negative peak ankle joint power, vertical ground reaction forces, and leg stiffness are similar between both movement modalities (1.8 G). In DJs, EMG activity in 1.8 G is lower during the COM deceleration phase than in 1 G, thus impairing quasi-isometric fascicle behavior. In DLs, EMG activity before and during the COM deceleration phase is higher, and fascicles are stretched less in 1.8 G than in 1 G. Compared with the situation in 1 G, highly task-specific neuromuscular activity is diminished in 1.8 G, resulting in fascicle lengthening in both movement modalities. Specifically, in DJs, a high magnitude of neuromuscular activity is impaired, resulting in altered energy storage. In contrast, in DLs, linear stiffening of the system due to higher neuromuscular activity combined with lower fascicle stretch enhances the buffering function of the tendon, and thus the capacity to safely dissipate energy.
Waldmann, Christoph ; Vera, Jean-Pierre de ; Dachwald, Bernd ; Strasdeit, Henry ; Sohl, Frank ; Hanff, Hendrik ; Kowalski, Julia ; Heinen, Dirk ; Macht, Sabine ; Bestmann, Ulf ; Meckel, Sebastian ; Hildebrandt, Marc ; Funke, Oliver ; Gehrt, Jan-Jöran
The quest for life on other planets is closely connected with the search for water in liquid state. Recent discoveries of deep oceans on icy moons like Europa and Enceladus have spurred an intensive discussion about how these waters can be accessed. The challenge of this endeavor lies in the unforeseeable requirements on instrumental characteristics both with respect to the scientific and technical methods. The TRIPLE/nanoAUV initiative is aiming at developing a mission concept for exploring exo-oceans and demonstrating the achievements in an earth-analogue context, exploring the ocean under the ice shield of Antarctica and lakes like Dome-C on the Antarctic continent.
Waiczies, Helmar ; Kühne, André ; Winter, Lukas ; Frauenrath, Tobias ; Hoffmann, Werner ; Ittermann, Bernd ; Waiczies, Sonia ; Niendorf, Thoralf
We have developed a double-tuned ¹H/¹⁹F birdcage resonator dedicated for hand and wrist imaging at 7 T to locally image non-steroidal anti-inflammatory drugs (NSAID) such as 2-{[3-(Trifluoromethyl) phenyl]amino}benzoic acid. The preliminary in vivo images acquired by the double-tuned ¹H/¹⁹F birdcage resonator demonstrate the feasibility for ¹H/¹⁹F hand- and wrist-imaging at 7 T. While the diagnostic quality of the coil needs to be assessed in patients with inflammatory rheumatoid disease, first ¹⁹F images of the NSAID are encouraging, and point towards the prospect of applying ¹⁹F-MRI to visualize and quantify the concentration of therapeutically-active compound at the sites of inflammation.
Generative Gestaltung: wie eine Herangehensweise die Zukunft des Designs revolutionieren könnte.
(2021)
Diese Bachelorarbeit setzt sich mit der „Generativen Gestaltung“ und ihren Möglichkeiten für Gestaltende auseinander. Die automatisierte Bearbeitung eines gestalterischen Projektes soll vorrangig Vorteile beim Arbeiten mit großen Datenmengen bieten.
Ziel war es, eine Plakatreihe zu entwerfen, die auf der Grundlage eines Codes - also eines strikten Regelwerks - basiert. Mithilfe dieses Verfahrens kann auf Knopfdruck eine beliebige Menge an Plakaten generiert werden. Durch die Festlegung bestimmter Parameter innerhalb des Codes wird gewährleistet, dass jedes ausgespielte Plakat anders ist als sein Vorgänger.
Diese Arbeit dient als eine erste anskizzierte Grundlage dafür, wie grafischer Output automatisiert und vor allem aktualisiert generiert werden kann. Dieses Prinzip kann auf eine Vielzahl von Inhalten und Umsetzungen angewendet werden.