Refine
Year of publication
- 2019 (387) (remove)
Institute
- FH Aachen (74)
- Fachbereich Medizintechnik und Technomathematik (71)
- IfB - Institut für Bioengineering (45)
- Fachbereich Elektrotechnik und Informationstechnik (44)
- Fachbereich Luft- und Raumfahrttechnik (44)
- Fachbereich Wirtschaftswissenschaften (35)
- Fachbereich Bauingenieurwesen (28)
- Fachbereich Energietechnik (27)
- Fachbereich Maschinenbau und Mechatronik (27)
- INB - Institut für Nano- und Biotechnologien (20)
- Fachbereich Chemie und Biotechnologie (16)
- Fachbereich Architektur (12)
- Solar-Institut Jülich (9)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (8)
- ECSM European Center for Sustainable Mobility (5)
- Institut fuer Angewandte Polymerchemie (5)
- Nowum-Energy (4)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (4)
- Fachbereich Gestaltung (3)
Document Type
- Article (123)
- Conference Proceeding (94)
- Administrative publication (72)
- Part of a Book (43)
- Book (25)
- Other (9)
- Doctoral Thesis (5)
- Patent (5)
- Review (4)
- Conference: Meeting Abstract (2)
Keywords
- Amtliche Mitteilung (68)
- Bachelor (31)
- Master (29)
- Prüfungsordnung (29)
- Lesbare Fassung (28)
- Studien- und Prüfungsordnung (21)
- Änderungsordnung (20)
- Bauingenieurwesen (17)
- Elektrotechnik (8)
- Holzingenieurwesen (6)
For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.