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- Einspielen <Werkstoff> (7)
- avalanche (5)
- Earthquake (4)
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Moreno i Codinachs, Lia ; Kloock, Joachim P. ; Schöning, Michael Josef ; Baldi, Antoni ; Ipatov, Andrey ; Bratov, Andrey ; Jimenez-Jorquera, Cecilia
Koch, Linda ; Wunderlich, F. Thomas ; Seibler, Jost ; Könner, A. Christine ; Hampel, Brigitte ; Irlenbusch, Sigrid ; Brabant, Georg ; Kahn, C. Ronald ; Schwenk, Frieder ; Brüning, Jens C.
Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice
(2008)
Christoph, Thomas ; Bahrenberg, Gregor ; Vry, Jean de ; Englberger, Werner ; Erdmann, Volker A. ; Frech, Moritz ; Kögel, Babette ; Röhl, Thomas ; Schiene, Klaus ; Schröder, Wolfgang ; Seibler, Jost ; Kurreck, Jens
Baumgartner, Werner ; Fidler, Florian ; Weth, Agnes ; Habbecke, Martin ; Jakob, Peter ; Butenweg, Christoph ; Böhme, Wolfgang
The sandfish (Scincus scincus) is a lizard having the remarkable ability to move through desert sand for significant distances. It is well adapted to living in loose sand by virtue of a combination of morphological and behavioural specializations. We investigated the bodyform of the sandfish using 3D-laserscanning and explored its locomotion in loose desert sand using fast nuclear magnetic resonance (NMR) imaging. The sandfish exhibits an in-plane meandering motion with a frequency of about 3 Hz and an amplitude of about half its body length accompanied by swimming-like (or trotting) movements of its limbs. No torsion of the body was observed, a movement required for a digging-behaviour. Simple calculations based on the Janssen model for granular material related to our findings on bodyform and locomotor behaviour render a local decompaction of the sand surrounding the moving sandfish very likely. Thus the sand locally behaves as a viscous fluid and not as a solid material. In this fluidised sand the sandfish is able to “swim” using its limbs.
Rationale: Previous studies [Topolnik et al., Cereb Cortex 2003; 13: 883; Schindler et al., Brain 2007; 130: 65] indicate that the termination of focal onset seizures may be causally related to an increase of global neuronal correlation during the second half of the seizures. This increase was observed to occur earlier in complex partial seizures than in secondarily generalized seizures. We here address the question whether such an increase of neuronal correlation prior to seizure end is indeed a global phenomenon, involving both hemispheres or whether there are side-specific differences. Methods: We analyzed 20 focal onset seizures (10 complex partial, 10 secondarily generalized seizures) recorded in 13 patients who underwent presurgical evaluation of focal epilepsies of different origin. EEG was recorded intracranially from bilaterally implanted subdural strip and intrahippocampal depth electrodes. Utilizing a moving window approach, we investigated the evolution of the maximum cross correlation for all channel combinations during seizures. For each moving window the mean value of the maximum cross correlation (MCC) between all electrode contacts was computed separately for each hemisphere. After normalization of seizure durations, MCC values of the ipsi- and contralateral hemisphere for all seizures were determined. Results: We observed that the MCC of the contralateral hemisphere in complex partial seizures increased during the first half of the seizure, whereas, for the same time interval, the MCC of the ipsilateral hemisphere even declined below the level of the pre-seizure period. In contrast, no significant differences between both hemispheres could be observed for secondarily generalized seizures where both hemispheres showed a simultaneous increase of MCC during the second half of the seizures. The level of MCC for the contralateral hemisphere was higher for complex partial seizures than for secondarily generalized seizures during the first half of the seizure. Conclusions: Our findings indicate that there are indeed lateralized differences in the evolution of global neuronal correlation during complex partial and secondarily generalized seizures. The observed contralateral increase of neuronal correlation during complex partial seizures might indicate an emerging self-organizing mechanism for preventing the spread of seizure activity.
Stadler, Andreas M. ; Zerlin, Kay ; Digel, Ilya ; Büldt, Georg ; Zaccai, Guiseppe ; Artmann, Gerhard
Soft Materials in Technology and Biology – Characteristics, Properties, and Parameter Identification
(2008)
Load bearing capacity of thin shell structures made of elastoplastic material by direct methods
(2008)
Stadler, Andreas M. ; Embs, Jan P. ; Digel, Ilya ; Artmann, Gerhard ; Unruh, Tobias ; Büldt, Georg ; Zaccai, Guiseppe
Scheer, Nico ; Ross, Jillian ; Rode, Anja ; Zevnik, Branko ; Niehaves, Sandra ; Faust, Nicole ; Wolf, C. Roland
Lerchl, Alexander ; Krüger, Heike ; Niehaus, Michael ; Streckert, Joachim R. ; Bitz, Andreas ; Hansen, Volkert
Abouzar, Maryam H. ; Poghossian, Arshak ; Razavi, Arash ; Besmehn, Astrid ; Bijnens, Nathalie ; Williams, Oliver A. ; Haenen, Ken ; Wagner, Patrick ; Schöning, Michael Josef
Schindler, Kaspar A. ; Bialonski, Stephan ; Horstmann, Marie-Therese ; Elger, Christian E. ; Lehnertz, Klaus
Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems
(2008)
Pita, Marcos ; Krämer, Melina ; Zouh, Jian ; Poghossian, Arshak ; Schöning, Michael Josef ; Fernandez, Victor M. ; Katz, Evgeny
Logic-based robot control in highly dynamic domains / Ferrein, Alexander ; Lakemeyer, Gerhard
(2008)
Usability engineering
(2008)
Foltz, Christian ; Schneider, Nicole ; Wolf, Martin R. ; Kausch, Bernhard ; Schlick, Christopher ; Luczak, Holger
Gun, Jenny ; Rizkov, Dan ; Lev, Ovadia ; Abouzar, Maryam H. ; Poghossian, Arshak ; Schöning, Michael Josef
Sensing charged macromolecules with nanocrystalline diamond-based field-effect capacitive sensors
(2008)
Poghossian, Arshak ; Abouzar, Maryam H. ; Christiaens, P. ; Williams, O. A. ; Haenen, K. ; Wagner, Patrick ; Schöning, Michael Josef
Due to the interfering effects of acetic acid in many fermentation processes, a gas-diffusion technique was developed for the online determination of acetic acid. The measurements were accomplished with a flow diffusion analysis (FDA) unit from the TRACE Analytics GmbH, Braunschweig, Germany. The diffusion analysis is based on the UV-absorbance of acetic acid at 205 nm. The measurement was achieved by the separation of an acceptor and a carrier stream (acidified fermentation broth) using a gas permeable polytetrafluoroethylene (PTFE) membrane, whereby broth constituents that would otherwise disturb the UV-measurement of acetic acid, are held back efficiently. Merely, the fermentation by-products, e.g. formic acid, is capable of diffusing through the membrane. While formic acid can disturb the measurement, carbon dioxide does not absorb at 205 nm. The method operates with time-dependent sample enrichment. During the analysis, a small volume of the acceptor stream is stopped for a defined time interval in the acceptor chamber. During this period, the gaseous acetic acid diffuses through the membrane and is enriched in the acceptor chamber. Subsequently after the enrichment, the acceptor stream flows through a UV-detector. The intensity of the signal is proportional to the acetic acid concentration. Online measurements in bioreactors via a sterile filtration probe have been accomplished. A linear calibration in the range of 0.5–5.0 g/L acetic acid with a relative standard deviation of <5 % was obtained. A sampling rate of 8 samples per hour was possible. The system was applied for the determination of acetic acid in E. coli fermentation broth. The instrument is easy to clean, very user-friendly and does not require any toxic or expensive reagents.
Calibration of a Network Analyzer Without a Thru Connection for Nonlinear and Multiport Measurements
(2008)
Magnetic Resonance Imaging (MRI) of moving organs requires synchronization with physiological motion or flow, which dictate the viable window for data acquisition. To meet this challenge, this study proposes an acoustic gating device (ACG) that employs acquisition and processing of acoustic signals for synchronization while providing MRI compatibility, immunity to interferences with electro-magnetic and acoustic fields and suitability for MRI at high magnetic field strengths. The applicability and robustness of the acoustic gating approach is examined in a pilot study, where it substitutes conventional ECG-gating for cardiovascular MR. The merits and limitations of the ACG approach are discussed. Implications for MR imaging in the presence of physiological motion are considered including synchronization with other structure- or motion borne sounds.
Musholt, Petra B. ; Schöndorf, Thomas ; Pfützner, Andreas ; Hohberg, Cloth ; Kleine, Iris ; Fuchs, Winfried ; Hehenwarter, Silvia ; Dikta, Gerhard ; Kerschgens, Benedikt ; Forst, Thomas
Jahnke, Siegfried ; Menzel, Marion I. ; Dusschoten, Dagmar van ; Roeb, Gerhard W. ; Bühler, Jonas ; Minwuyelet, Senay ; Blümler, Peter ; Temperton, Vicky M. ; Hombach, Thomas ; Streun, Matthias ; Beer, Simone ; Khodaverdi, Maryam ; Ziemons, Karl ; Coenen, Heinz H. ; Schurr, Ulrich
Unravelling the factors determining the allocation of carbon to various plant organs is one of the great challenges of modern plant biology. Studying allocation under close to natural conditions requires non-invasive methods, which are now becoming available for measuring plants on a par with those developed for humans. By combining magnetic resonance imaging (MRI) and positron emission tomography (PET), we investigated three contrasting root/shoot systems growing in sand or soil, with respect to their structures, transport routes and the translocation dynamics of recently fixed photoassimilates labelled with the short-lived radioactive carbon isotope 11C. Storage organs of sugar beet (Beta vulgaris) and radish plants (Raphanus sativus) were assessed using MRI, providing images of the internal structures of the organs with high spatial resolution, and while species-specific transport sectoralities, properties of assimilate allocation and unloading characteristics were measured using PET. Growth and carbon allocation within complex root systems were monitored in maize plants (Zea mays), and the results may be used to identify factors affecting root growth in natural substrates or in competition with roots of other plants. MRI–PET co-registration opens the door for non-invasive analysis of plant structures and transport processes that may change in response to genomic, developmental or environmental challenges. It is our aim to make the methods applicable for quantitative analyses of plant traits in phenotyping as well as in understanding the dynamics of key processes that are essential to plant performance.
Wedrowski, M. ; Bruyndonckx, P. ; Tavernier, S. ; Zhi, L. ; Dang, J. ; Mendes, P. R. ; Perez, J. M. ; Ziemons, Karl
The monolithic scintillator block approach for gamma detection in the Positron Emission Tomography (PET) avoids estimating Depth of Interaction (DOI), reduces dead zones in detector and diminishes costs of detector production. Neural Networks (NN) are very efficient to determine the entrance point of a gamma incident on a scintillator block. This paper presents results on the robustness of the spatial resolution as a function of the random fraction in the data, temperature and HV fluctuations. This is important when implementing the method in a real scanner. Measurements were done with two Hamamatsu S8550 APD arrays, glued on a 20 Ã 20 Ã 10 mm3 monolithic LSO crystal block.
The readout of gamma detectors is considerably simplified when the event intensity is encoded as a pulse width (Pulse Width Modulation, PWM). Time-to-Digital-Converters (TDC) replace the conventional ADCs and multiple TDCs can be realized easily in one PLD chip (Programmable Logic Device). The output of a PWM stage is only one digital signal per channel which is well suited for transport so that further processing can be performed apart from the detector. This is particularly interesting for large systems with high channel density (e.g. high resolution scanners). In this work we present a circuit with a linear transfer function that requires a minimum of components by performing the PWM already in the preamp stage. This allows a very compact and also cost-efficient implementation of the front-end electronics.
Miyamoto, Ko-ichiro ; Wagner, Torsten ; Mimura, Shuhei ; Kanoh, Shin`ichiro ; Yoshinobu, Tatsuo ; Schöning, Michael Josef
Kirchner, Patrick ; Li, B. ; Spelthahn, H. ; Henkel, H. ; Friedrich, P. ; Kolstad, J. ; Keusgen, M. ; Schöning, Michael Josef
Schöning, Michael Josef ; Turek, M. ; Heiden, W. ; Riesen, A. ; Chhabda, T. A. ; Schubert, J. ; Krüger, P. ; Keusgen, M.
Next Generation Access Networks: Why is there a higher risk of investment and how to deal with it?
(2009)
Behbahani, Mehdi ; Behr, M. ; Hormes, M. ; Steinseifer, U. ; Arora, D. ; Coronado, O. ; Pasquali, M.
Steinseifer, Ulrich ; Kashefi, Ali ; Hormes, Marcus ; Schoberer, Mark ; Orlikowsky, Thorsten ; Behbahani, Mehdi ; Behr, Marek ; Schmitz-Rode, Thomas
Öhlschläger, Peter ; Quetting, Michael ; Alvarez, Gerardo ; Dürst, Matthias ; Gissmann, Lutz ; Kaufmann, Andreas M.
The powerful avalanche simulation toolbox RAMMS (Rapid Mass Movements) is based on a depth-averaged
hydrodynamic system of equations with a Voellmy-Salm friction relation. The two empirical friction parameters
μ and correspond to a dry Coulomb friction and a viscous resistance, respectively. Although μ and lack a
proper physical explanation, 60 years of acquired avalanche data in the Swiss Alps made a systematic calibration
possible. RAMMS can therefore successfully model avalanche flow depth, velocities, impact pressure and run
out distances. Pudasaini and Hutter (2003) have proposed extended, rigorously derived model equations that
account for local curvature and twist. A coordinate transformation into a reference system, applied to the actual
mountain topography of the natural avalanche path, is performed. The local curvature and the twist of the
avalanche path induce an additional term in the overburden pressure. This leads to a modification of the Coulomb
friction, the free-surface pressure gradient, the pressure induced by the channel, and the gravity components
along and normal to the curved and twisted reference surface. This eventually guides the flow dynamics and
deposits of avalanches. In the present study, we investigate the influence of curvature on avalanche flow in
real mountain terrain. Simulations of real avalanche paths are performed and compared for the different models
approaches. An algorithm to calculate curvature in real terrain is introduced in RAMMS. This leads to a curvature
dependent friction relation in an extended version of the Voellmy-Salm model equations. Our analysis provides
yet another step in interpreting the physical meaning and significance of the friction parameters used in the
RAMMS computational environment.
Miyamoto, K. ; Kuwabara, Yohei ; Kanoh, Shin'ichiro ; Yoshinobu, Tatsuo ; Wagner, Torsten ; Schöning, Michael Josef