Part of a Book
Refine
Year of publication
Institute
- Fachbereich Bauingenieurwesen (86)
- Fachbereich Energietechnik (83)
- Fachbereich Wirtschaftswissenschaften (74)
- Fachbereich Elektrotechnik und Informationstechnik (67)
- Fachbereich Medizintechnik und Technomathematik (63)
- Fachbereich Architektur (48)
- Fachbereich Luft- und Raumfahrttechnik (43)
- Fachbereich Gestaltung (40)
- IfB - Institut für Bioengineering (38)
- Fachbereich Maschinenbau und Mechatronik (32)
Has Fulltext
- no (574) (remove)
Document Type
- Part of a Book (574) (remove)
Keywords
- Aktionskunst (4)
- Papierkunst (4)
- Wind Tunnel (3)
- Autonomous mobile robots (2)
- Central receiver power plant (2)
- Central receiver system (2)
- Concentrated solar collector (2)
- Concentrated systems (2)
- Datenschutz (2)
- Datenschutzrecht (2)
- Digitale Transformation (2)
- EU-Datenschutzgrundverordnung (2)
- Engineering optimization (2)
- Flight Test (2)
- Gas turbine (2)
- Geschichte (2)
- IT-Sicherheit (2)
- Industry 4.0 (2)
- Interaktive Kunst (2)
- Internationales Recht / Europarecht (2)
- Kommunikationsguerrilla (2)
- Multi-robot systems (2)
- Pitching Moment (2)
- Prozessautomatisierung (2)
- Seismic design (2)
- Smart factory (2)
- Solar concentration (2)
- Stadtgestaltung (2)
- Streetart (2)
- Wave Drag (2)
- robotic process automation (2)
- Öffentlicher Raum (2)
- 20 fossil-fueled power plants (1)
- 3D printing (1)
- Acceptance tests (1)
- Additive manufacturing (1)
- Advanced driver assistance systems (ADAS/AD) (1)
- Aerodynamic Drag (1)
- Analytics (1)
- BEV (1)
- Best practice sharing (1)
- Betroffenenrechte (1)
- Bioeconomy (1)
- Bioethanol (1)
- Biomolecular logic gate (1)
- Biorefinery (1)
- Biorefinery definitions (1)
- Bladder (1)
- Bone sawing (1)
- Bundesdatenschutzgesetz (2017) (1)
- Business Models (1)
- Business understanding (1)
- Calorimetric gas sensor (1)
- Carsharing (1)
- Certification Rule (1)
- Change culture (1)
- Change management (1)
- Charging stations (1)
- Chemical imaging (1)
- Chimeric liver-humanized mice (1)
- Cloud Computing (1)
- Coat protein (1)
- Coefficient of ocular rigidity (1)
- Cognitive assistance system (1)
- Collaborative robot (1)
- Collagen fibrils (1)
- Components (1)
- Concentrating solar power (1)
- Connective tissues (1)
- Controller Parameter (1)
- Corneo-scleral shell (1)
- Cross-platform (1)
- Customer Experience Management (1)
- Customer Journeys (1)
- Cyber-physical systems (1)
- Cybersecurity (1)
- Cybersicherheit (1)
- DNA (1)
- Datenschutzfolgenabschätzung (1)
- Datenschutzgrundverordnung (1)
- Decentral (1)
- Design examples (1)
- Designstudium (1)
- Differential tonometry (1)
- Digital leadership (1)
- Digital manufacturing (1)
- Digitalisierung (1)
- Diversity management (1)
- Drag Reduction (1)
- Drug distribution (1)
- Drug metabolism (1)
- Dry surfaces (1)
- E-carsharing (1)
- E-mobility (1)
- EU-DS-GVO (1)
- EU-DSGVO (1)
- EUDSGVO (1)
- Electrical vehicle (1)
- Energy efficiency (1)
- Engine Efficiency (1)
- Entstaubung (1)
- Enzyme biosensor (1)
- Enzyme nanocarrier (1)
- Epistemische Neugier (1)
- Eurocode 8 (1)
- Evacuation Rule (1)
- Evaluation (1)
- Experteninterviews (1)
- Extracellular matrix (ECM) (1)
- Eyeball (1)
- FGF23 (1)
- Fake (1)
- Field-effect device (1)
- Field-effect sensor (1)
- Filter (Stofftrennung) (1)
- Filtration (1)
- Forschung (1)
- Forschungsinformationssystem (1)
- Forschungsprozess (1)
- Fresnel collector (1)
- Fresnel power plant (1)
- Friction Drag (1)
- Fully connected car (1)
- Gamification (1)
- Gearbox (1)
- Geschäftsprozessmanagement (1)
- Global optimization (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Gold nanoparticle (1)
- Growth modelling (1)
- Gust wind response (1)
- Hacking (1)
- Higher education (1)
- Hochschule (1)
- Human-Robot interaction (1)
- Human-centered work design (1)
- Human-robot collaboration (1)
- Hybridization (1)
- Hydraulic structures (1)
- Hydrogen peroxide (1)
- ISO 26262 (1)
- IT Products (1)
- IT-Marketing (1)
- Ice melting probe (1)
- Ice penetration (1)
- Icy moons (1)
- Identitätsmanagement (1)
- Illustration (1)
- Im-plementation of AI-systems (1)
- Inclusive work climate (1)
- Inductive charging (1)
- Industrial units (1)
- Information and communication technology (1)
- Informationsgetriebene Geschäftsmodelle (1)
- Informationssicherheit (1)
- Informationssicherheitsmanagement (1)
- Integrated mobility (1)
- Intelligentes Parken (1)
- Interactive process mining (1)
- Internet der Dinge (1)
- Introduction (1)
- Kinetische Kunst (1)
- Klotho (1)
- Knockout mice (1)
- Kommerzielle Interaktionen (1)
- Konsumgesellschaft (1)
- Konsumkritik (1)
- Kreativität (1)
- Künstlerische Intervention (1)
- Künstlerisches Handeln (1)
- Leaderboard (1)
- Leading Edge Vortex (1)
- Lean thinking (1)
- Level Control System (1)
- Lichtkunst (1)
- Light-addressable potentiometric sensor (1)
- Lignocellulose feedstook (1)
- Limit analysis (1)
- MINLP (1)
- Mach Number (1)
- Machine learning (1)
- Mack, Heinz (1)
- Mars (1)
- Mechanical (1)
- Mechanical simulation (1)
- Mechanical stability (1)
- Meinungsäußerung (1)
- Methodology (1)
- Microbial adhesion (1)
- Mixed-Methods (1)
- Mixed-Methods Research (1)
- Mixed-integer nonlinear black-box optimization (1)
- Mixed-integer nonlinear problem (1)
- Mobile web (1)
- Mobility management (1)
- Monetarisierung (1)
- Multi-criteria optimization (1)
- Multi-sensor system (1)
- Multidisciplinary Design Optimization (1)
- Multimode failure (1)
- Muscle fibers (1)
- Network (1)
- Netzkunst (1)
- Niacin (1)
- Noise Exposure (1)
- Non-linear optimization (1)
- Objective data (1)
- Ocean worlds (1)
- On-site (1)
- Open channels (1)
- Optical and thermal analysis (1)
- Optimal Closed Loop (1)
- Optimal Topology (1)
- Optimization (1)
- Organizational culture (1)
- PTH (1)
- PWA (1)
- Paper recycling (1)
- Parabolized Stability Equation (1)
- Parasitäre Strategie (1)
- Parasitäre Strategien (1)
- Participation (1)
- Passenger compartment (1)
- Passive stretching (1)
- Path planning (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Perception (1)
- Performance measurement (1)
- Phosphate (1)
- Physical modeling (1)
- Plant efficiency (1)
- Politische Kunst (1)
- Potentiometry (1)
- Power conversion systems (1)
- Powertrain (1)
- Pre-treatment (1)
- Pressure-volume relationship (1)
- Privacy (1)
- Process engineering (1)
- Process model (1)
- Process schemes (1)
- Product Management (1)
- Product family optimization (1)
- Progressive Web App (1)
- Projektbeispiele (1)
- Prozessagilität (1)
- Prozessauswahl (1)
- Prozessverbesserung (1)
- Psychological concepts (1)
- Pushover analysis (1)
- Qualitative Wertschöpfungsanalyse (1)
- Quantitative research (1)
- RWTH Aachen University (1)
- Rapid manufacturing (1)
- Rapid prototyping (1)
- Raumerfahrung (1)
- Reconstruction (1)
- Reliability analysis (1)
- Renewable resources (1)
- Requirements (1)
- Response spectrum (1)
- Responsibility (1)
- Riboflavin (1)
- RoboCup (1)
- Robotic Process Automation (1)
- Robotic process automation (1)
- Safety concept (1)
- Safety of the intended functionality (SOTIF) (1)
- Safety-critical systems validation (1)
- Sampling methods (1)
- Selbstwirksamkeit (1)
- Selektionskriterien (1)
- Serviceintegration (1)
- Severe Accident (1)
- Shakedown analysis (1)
- Silos (1)
- Similitude (1)
- Software development (1)
- Software testing (1)
- Softwareroboter (1)
- Solar dish (1)
- Sonic Boom (1)
- Specific Fuel Consumption (1)
- Spectral analysis (1)
- Stadtentwicklung (1)
- Staubfilter (1)
- Strategic Business Planning (1)
- Strickmuster (1)
- Students (1)
- Studienarbeit (1)
- Studieneingangsphase (1)
- Studierfähigkeit (1)
- Supersonic Flow (1)
- Supersonic Wind Tunnel (1)
- Surface microorganisms (1)
- Swabbing (1)
- Tanks (1)
- Tapered ends (1)
- Technical Operation Research (1)
- Technische Schutzmaßnahmen (1)
- Technology Challenge (1)
- Telekommunikation-Telemedien-Datenschutzgesetz (1)
- Thermal Fatigue Testing (1)
- Thermal comfort (1)
- Thermal management (1)
- Thiamine (1)
- Tobacco mosaic virus (TMV) (1)
- Toxicology (1)
- Transition (1)
- Typologien (1)
- Urban areas (1)
- Urbanismus (1)
- Ureter (1)
- Variable Geometry (1)
- Verweigerung (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- WLTP (1)
- Water (1)
- Wind turbulence (1)
- Wirkungsforschung (1)
- Workspace monitoring (1)
- applications (1)
- architectural education (1)
- artificial intelligence (1)
- attitude dynamics (1)
- bullying (1)
- business process automation (1)
- ceramics (1)
- commercial offthe- shelf solutions (1)
- culpability (1)
- currriculum (1)
- design research (1)
- dscipline (1)
- filtration (1)
- gas flow (1)
- hot gas cleanup (1)
- hybridity (1)
- intrinsische Motivation (1)
- keramischer Werkstoff (1)
- lessons learned (1)
- liability (1)
- management (1)
- orbit control (1)
- orbital dynamics (1)
- policy recommendations (1)
- profession (1)
- recommendations for actions (1)
- research by design (1)
- research framework (1)
- research in architecture (1)
- sailcraft (1)
- software evaluation (1)
- software selection (1)
- solar sail (1)
- technology (1)
- the University of Sheffield (1)
- training simulator (1)
- virtual reality (1)
Sampling of dry surfaces for microorganisms is a main component of microbiological safety and is of critical importance in many fields including epidemiology, astrobiology as well as numerous branches of medical and food manufacturing. Aspects of biofilm formation, analysis and removal in aqueous solutions have been thoroughly discussed in literature. In contrast, microbial communities on air-exposed (dry) surfaces have received significantly less attention. Diverse surface sampling methods have been developed in order to address various surfaces and microbial groups, but they notoriously show poor repeatability, low recovery rates and suffer from lack of mutual consistency. Quantitative sampling for viable microorganisms represents a particular challenge, especially on porous and irregular surfaces. Therefore, it is essential to examine in depth the factors involved in microorganisms’ recovery efficiency and accuracy depending on the sampling technique used. Microbial colonization, retention and community composition on different dry surfaces are very complex and rely on numerous physicochemical and biological factors. This study is devoted to analyze and review the (a) physical phenomena and intermolecular forces relevant for microbiological surface sampling; (b) challenges and problems faced by existing sampling methods for viable microorganisms and (c) current directions of engineering and research aimed at improvement of quality and efficiency of microbiological surface sampling.
For pelvic floor disorders that cannot be treated with non-surgical procedures, minimally invasive surgery has become a more frequent and safer repair procedure. More than 20 million prosthetic meshes are implanted each year worldwide. The simple selection of a single synthetic mesh construction for any level and type of pelvic floor dysfunctions without adopting the design to specific requirements increase the risks for mesh related complications. Adverse events are closely related to chronic foreign body reaction, with enhanced formation of scar tissue around the surgical meshes, manifested as pain, mesh erosion in adjacent structures (with organ tissue cut), mesh shrinkage, mesh rejection and eventually recurrence. Such events, especially scar formation depend on effective porosity of the mesh, which decreases discontinuously at a critical stretch when pore areas decrease making the surgical reconstruction ineffective that further augments the re-operation costs. The extent of fibrotic reaction is increased with higher amount of foreign body material, larger surface, small pore size or with inadequate textile elasticity. Standardized studies of different meshes are essential to evaluate influencing factors for the failure and success of the reconstruction. Measurements of elasticity and tensile strength have to consider the mesh anisotropy as result of the textile structure. An appropriate mesh then should show some integration with limited scar reaction and preserved pores that are filled with local fat tissue. This chapter reviews various tissue reactions to different monofilament mesh implants that are used for incontinence and hernia repairs and study their mechanical behavior. This helps to predict the functional and biological outcomes after tissue reinforcement with meshes and permits further optimization of the meshes for the specific indications to improve the success of the surgical treatment.
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) today are widely used for the investigation of normal electromechanical cardiac function, of cardiac medication and of mutations. Computational models are thus established that simulate the behavior of this kind of cells. This section first motivates the modeling of hiPS-CM and then presents and discusses several modeling approaches of microscopic and macroscopic constituents of human-induced pluripotent stem cell-derived and mature human cardiac tissue. The focus is led on the mapping of the computational results one can achieve with these models onto mature human cardiomyocyte models, the latter being the real matter of interest. Model adaptivity is the key feature that is discussed because it opens the way for modeling various biological effects like biological variability, medication, mutation and phenotypical expression. We compare the computational with experimental results with respect to normal cardiac function and with respect to inotropic and chronotropic drug effects. The section closes with a discussion on the status quo of the specificity of computational models and on what challenges have to be solved to reach patient-specificity.
Reconstructive surgery and tissue replacements like ureters or bladders reconstruction have been recently studied, taking into account growth and remodelling of cells since living cells are capable of growing, adapting, remodelling or degrading and restoring in order to deform and respond to stimuli. Hence, shapes of ureters or bladders and their microstructure change during growth and these changes strongly depend on external stimuli such as training. We present the mechanical stimulation of smooth muscle cells in a tubular fibrin-PVDFA scaffold and the modelling of the growth of tissue by stimuli. To this end, mechanotransduction was performed with a kyphoplasty balloon catheter that was guided through the lumen of the tubular structure. The bursting pressure was examined to compare the stability of the incubated tissue constructs. The results showed the significant changes on tissues with training by increasing the burst pressure as a characteristic mechanical property and the smooth muscle cells were more oriented with uniformly higher density. Besides, the computational growth models also exhibited the accurate tendencies of growth of the cells under different external stimuli. Such models may lead to design standards for the better layered tissue structure in reconstructing of tubular organs characterized as composite materials such as intestines, ureters and arteries.
Mechanical forces/tensile stresses are critical determinants of cellular growth, differentiation and migration patterns in health and disease. The innovative “CellDrum technology” was designed for measuring mechanical tensile stress of cultured cell monolayers/thin tissue constructs routinely. These are cultivated on very thin silicone membranes in the so-called CellDrum. The cell layers adhere firmly to the membrane and thus transmit the cell forces generated. A CellDrum consists of a cylinder which is sealed from below with a 4 μm thick, biocompatible, functionalized silicone membrane. The weight of cell culture medium bulbs the membrane out downwards. Membrane indentation is measured. When cells contract due to drug action, membrane, cells and medium are lifted upwards. The induced indentation changes allow for lateral drug induced mechanical tension quantification of the micro-tissues. With hiPS-induced (human) Cardiomyocytes (CM) the CellDrum opens new perspectives of individualized cardiac drug testing. Here, monolayers of self-beating hiPS-CMs were grown in CellDrums. Rhythmic contractions of the hiPS-cells induce membrane up-and-down deflections. The recorded cycles allow for single beat amplitude, single beat duration, integration of the single beat amplitude over the beat time and frequency analysis. Dose effects of agonists and antagonists acting on Ca2+ channels were sensitively and highly reproducibly observed. Data were consistent with published reference data as far as they were available. The combination of the CellDrum technology with hiPS-Cardiomyocytes offers a fast, facile and precise system for pharmacological and toxicological studies. It allows new preclinical basic as well as applied research in pharmacolgy and toxicology.
Lepautre
(2015)
Ranson, Pierre
(2017)
Patte, Pierre
(2017)
Peyre, Antoine-Francois
(2017)
Peyre, Marie-Josephe
(2017)
Digitalisierung bezeichnet die Nutzung großer Datenmengen, die zu einer umfassenden Vernetzung aller Bereiche der Wirtschaft und Gesellschaft führen wird (BMWi, 2015 und ähnlich Köhler/Wollschläger, 2014: 79). Sie umfasst die Erhebung von analogen Informationen („Big Data“ in einem engen Sinne; z.B. O´Leary, 2013), ihre Speicherung in einem digitaltechnischen System (lokale Speicherung oder „Cloud Computing“ durch die Weiterentwickelung des Internets; z.B. Hashem et al., 2015: 101), die Analyse und Interpretation sowie den Transfer in andere Systeme („Internet der Dinge“ bzw. „Internet of Things“; z.B. Ashton, 2009).