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For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described.
Knott, Thomas C. ; Sofronia, Raluca E. ; Gerressen, Marcus ; Law, Yuen ; Davidescu, Arjana ; Savii, George G. ; Gatzweiler, Karl-Heinz ; Staat, Manfred ; Kuhlen, Torsten W.
Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.
Frotscher, Ralf ; Goßmann, Matthias ; Raatschen, Hans-Jürgen ; Temiz Artmann, Aysegül ; Staat, Manfred
We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Niemüller, Tim ; Ewert, Daniel ; Reuter, Sebastian ; Ferrein, Alexander ; Jeschke, Sabina ; Lakemeyer, Gerhard
A new trend in automation is to deploy so-called cyber-physical systems (CPS) which combine computation with physical processes. The novel RoboCup Logistics League Sponsored by Festo (LLSF) aims at such CPS logistic scenarios in an automation setting. A team of robots has to produce products from a number of semi-finished products which they have to machine during the game. Different production plans are possible and the robots need to recycle scrap byproducts. This way, the LLSF is a very interesting league offering a number of challenging research questions for planning, coordination, or communication in an application-driven scenario. In this paper, we outline the objectives of the LLSF and present steps for developing the league further towards a benchmark for logistics scenarios for CPS. As a major milestone we present the new automated referee system which helps in governing the game play as well as keeping track of the scored points in a very complex factory scenario.
IT Products are viewed and managed differently depending on the perspectives and the stage within the life cycle. A model is presented that integrates different perspectives and stages serving as an aid for the analysis of business models and focused positioning of IT-products. Four generic business models are analysed with regard to the product management function in general and the positioning field for IT-products specifically: off-the-shelf (license), license plus service, project, and system service (incl. cloud computing).
Siegert, Petra ; Pohl, Martina ; Kneen, Malea M. ; Pogozheva, Irina D. ; Kenyon, George L. ; McLeish, Michael J.
Wendorff, Marion ; Eggert, Thorsten ; Pohl, Martina ; Dresen, Carola ; Müller, Michael ; Jaeger, Karl-Erich ; Sprenger, Georg A. ; Schürmann, Melanie ; Schürmann, Martin ; Johnen, Sandra ; Sprenger, Gerda ; Sahm, Hermann ; Inoue, Tomoyuki ; Schörken, Ulrich ; Breittaupt, Holger ; Frölich, Bettina ; Heim, Petra ; Iding, Hans ; Juchem, Bettina ; Siegert, Petra ; Kula, Maria-Regina ; Weckbecker, Andrea ; Hummel, Werner ; Fessner, Wolf-Dieter ; Elling, Lothar ; Wolberg, Michael ; Bode, Silke ; Feldmann, Ralf ; Geilenkirchen, Petra ; Schubert, Thomas ; Walter, Lydia ; Dünnwald, Thomas ; Demir, Ayhan S. ; Kolter-Jung, Doris ; Nitsche, Adam ; Dünkelmann, Pascal ; Cosp, Annabel ; Lingen, Bettina
An array of electrically isolated nanoplate field-effect silicon-on-insulator (SOI) capacitors as a new transducer structure for multiparameter (bio-)chemical sensing is presented. The proposed approach allows addressable biasing and electrical readout of multiple nanoplate field-effect capacitive (bio-)chemical sensors on the same SOI chip, as well as differential-mode measurements. The realized sensor chip has been applied for pH and penicillin concentration measurements, electrical monitoring of polyelectrolyte multilayer formation, and the label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization and denaturation events.
TOP-Energy : softwaregestützte Analyse und Optimierung industrieller Energieversorgungssysteme
(2004)