Refine
Year of publication
Institute
- Fachbereich Medizintechnik und Technomathematik (1931) (remove)
Has Fulltext
- no (1931) (remove)
Document Type
- Article (1546)
- Conference Proceeding (152)
- Book (96)
- Part of a Book (62)
- Doctoral Thesis (27)
- Patent (17)
- Report (13)
- Other (8)
- Habilitation (4)
- Preprint (3)
- Review (1)
- Talk (1)
- Working Paper (1)
Keywords
- LAPS (4)
- Natural language processing (4)
- CellDrum (3)
- Field-effect sensor (3)
- Light-addressable potentiometric sensor (3)
- Paired sample (3)
- hydrogen peroxide (3)
- impedance spectroscopy (3)
- Bacillus atrophaeus (2)
- Biocomposites (2)
- Boundary integral equations (2)
- Clustering (2)
- Conductive boundary condition (2)
- Empirical process (2)
- Force (2)
- Goodness-of-fit test (2)
- Incomplete data (2)
- Independence test (2)
- Information extraction (2)
- Iterative learning control (2)
- Limit analysis (2)
- Machine learning (2)
- Natural fibres (2)
- Parametric bootstrap (2)
- Polymer-matrix composites (2)
- Raman spectroscopy (2)
- Shakedown analysis (2)
- Simulation (2)
- Stiffness (2)
- Stress concentrations (2)
- Transmission eigenvalues (2)
- biopotential electrodes (2)
- constructive alignment (2)
- damage (2)
- examination (2)
- field-effect sensor (2)
- frequency mixing magnetic detection (2)
- likelihood ratio test (2)
- locomotion (2)
- long-term retention (2)
- multimodal (2)
- muscle fascicle behavior (2)
- not identically distributed (2)
- practical learning (2)
- tobacco mosaic virus (TMV) (2)
- ultrasound (2)
- ultrasound imaging (2)
- (Bio)degradation (1)
- Acceleration (1)
- Achilles tendon (1)
- Active learning (1)
- Adaptive control (1)
- Afterload (1)
- Ageing (1)
- Agent-based modeling (1)
- Agent-based simulation (1)
- AlterG (1)
- Alzheimer's disease (1)
- Analytical models (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Architectural gear ratio (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Asymptotic relative efficiency (1)
- Autolysis (1)
- Automatic control (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Balance (1)
- Bein (1)
- Biomechanical simulation (1)
- Biomolecular logic gate (1)
- Biosolubilization (1)
- Bladder (1)
- Bone sawing (1)
- Booster Station (1)
- Bootstrap (1)
- Bootstrapping (1)
- Boundary integral equations, (1)
- Brennkraftmaschine (1)
- Brennstoffeinspritzsystem (1)
- Brownian Pillow (1)
- CNOT (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cementoblast (1)
- Censored data (1)
- Chance constrained programming (1)
- Chemical images (1)
- Chemical imaging (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Choleratoxin B (1)
- Circular Dichroism (1)
- Cloud Computing (1)
- Cloud Service Broker (1)
- Co-managed care (1)
- Coal (1)
- Coat protein (1)
- Coefficient of ocular rigidity (1)
- Collective risk model (1)
- Comparative simulation (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conductive Boundary Condition (1)
- Conservation laws (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Corneo-scleral shell (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Cross border adjustment mechanism (1)
- Crámer–von-Mises distance (1)
- C–V method (1)
- DNA (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Database (1)
- Decomposition (1)
- Deep Learning (1)
- Deep learning (1)
- Dehydrogenase (1)
- Diaphorase (1)
- Differential tonometry (1)
- Dimensional splitting (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discrete Optimization (1)
- Distorsion des oberen Sprunggelenks (1)
- Drug simulation (1)
- Dry surfaces (1)
- E-Mobility (1)
- EEG (1)
- EIS capacitive sensor (1)
- ES-FEM (1)
- Effizienz (1)
- Eigenvalue trajectories (1)
- Elderly (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Elektroenzephalographie (1)
- Elektromyographie (1)
- Elektrostimulation (1)
- Elemental (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Energy dispatch (1)
- Energy market (1)
- Energy market design (1)
- Energy-intensive industry (1)
- Entropy solution (1)
- Enzymatic biosensor (1)
- Enzyme biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme nanocarrier (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- Evolution of damage (1)
- Exponential Euler scheme, (1)
- Exponential time differencing (1)
- Extension fracture (1)
- Extension strain criterion (1)
- Extensor (1)
- External knee adduction moments (1)
- Eyeball (1)
- FGF23 (1)
- FS-FEM (1)
- Fall prevention (1)
- Field effect (1)
- Field-effect biosensor (1)
- Field-effect device (1)
- Finite difference methods (1)
- Finite element analysis (1)
- Finite element analysis (FEA) (1)
- Finite element modelling (1)
- Floor prices (1)
- Focusing (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Gamma distribution (1)
- Glaucoma (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Gold nanoparticle (1)
- Goodness-of-fit tests for uniformity (1)
- Grid Computing (1)
- Ground-level falls (1)
- Growth modelling (1)
- H2 (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Handbike (1)
- Heart tissue culture (1)
- Helmholtz equation (1)
- Heterostructure (1)
- Higher-order codes (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Human-Computer interaction (1)
- Hydrogen peroxide (1)
- Hydrogenotrophic methanogens (1)
- Hypothesentests (1)
- Image Reconstruction (1)
- Impedance Spectroscopy (1)
- Impedance spectroscopy (1)
- Implicit methods (1)
- Induced pluripotent stem cells (1)
- Information Extraction (1)
- Inotropic compounds (1)
- Instruments (1)
- Integrated empirical distribution (survival) function (1)
- Interior Neumann eigenvalues (1)
- Interior transmission eigenvalues (1)
- Interior transmission problem (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering (1)
- Inverse spectral problem (1)
- Ion channels (1)
- Kinetic energy (1)
- Klotho (1)
- Knee (1)
- Krypton (1)
- Krypton-85 (1)
- LPS (1)
- Lab-on-Chip (1)
- Label-free detection (1)
- Langevin theory (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Light-addressable Potentiometric Sensor (1)
- Lipopolysaccharide (1)
- Liver (1)
- Load modeling (1)
- Long COVID (1)
- MOS (1)
- Magnetic nanoparticles (1)
- Manipulated variables (1)
- Marginal homogeneity (1)
- Marginal homogeneity test (1)
- Market modeling (1)
- Matrix exponential (1)
- Measurement (1)
- Mechanical simulation (1)
- Mechanotransduction (1)
- Metascintillator (1)
- Methane (1)
- Methanogenesis (1)
- Microbial adhesion (1)
- Microcirculation (1)
- Micromagnetic simulation (1)
- Mild cognitive impairment (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Mohr–Coulomb criterion (1)
- Monotone methods (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional partial differential equations (1)
- Multi-sample problem (1)
- Multianalyte detection (1)
- Multimode failure (1)
- Multiple TOF kernels (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Muscle fibers (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Natural Language Processing (1)
- Natural language understanding (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Neuromuskuläres System (1)
- Niacin (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-linear optimization (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nonlinear PDEs (1)
- Nonlinear eigenvalue problems (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- Numerics (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Open Data (1)
- Open source (1)
- Organic light-emitting diode display (1)
- PTH (1)
- Parabolic SPDEs (1)
- Paralympic sport (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Penicillin (1)
- Pharmacology (1)
- Phosphate (1)
- Physiology (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Post-COVID-19 syndrome (1)
- Potential theory (1)
- Potentiometry (1)
- Preference assessment (1)
- Pressure-volume relationship (1)
- Process model (1)
- Product-integration (1)
- Profile Extraction (1)
- Profile extraction (1)
- Proximal humerus fracture (1)
- Psychiatrische Biomarker (1)
- Pulsations (1)
- Pump System (1)
- Query learning (1)
- RVA (1)
- Raumfahrt (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Reconstruction (1)
- Refining (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Rehabilitationsmedizin (1)
- Rehabilitatives Training (1)
- Relation classification (1)
- Reliability analysis (1)
- Reliability of structures (1)
- Renewable energy sources (1)
- Reproducible research (1)
- Resampling test (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Robotik (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- Sampling methods (1)
- ScaLAPACK (1)
- Schlafspindeldetektion (1)
- Semi-parametric random censorship model (1)
- Septic cardiomyopathy (1)
- Simultaneous determination (1)
- Sleep EEG (1)
- Sn₃O₄ (1)
- Source term (1)
- Spleen (1)
- Sprunggelenkorthesen (1)
- Steel industry (1)
- Sterilisation process (1)
- Stochastic programming (1)
- SunRav BookEditor (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Swabbing (1)
- TMV adsorption (1)
- TOF PET (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (TOR) (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tension (1)
- Text Mining (1)
- Text mining (1)
- Thiamine (1)
- Time-series (1)
- Tinetti test (1)
- Tobacco mosaic virus (1)
- Tobacco mosaic virus (TMV) (1)
- Training (1)
- Trainingsgerät (1)
- Transmission Eigenvalues (1)
- Trinkwassersicherheit (1)
- Trustworthy artificial intelligence (1)
- Uniaxial compression test (1)
- Ureter (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vergleich von Experimenten (1)
- Visual field asymmetry (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Volumes of confidence regions (1)
- Workflow (1)
- Workflow Orchestration (1)
- XOR (1)
- Xenon (1)
- acetoin (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- allocation (1)
- anaesthetic complications (1)
- anisotropy (1)
- ankle braces (1)
- ankle sprain (1)
- annealing (1)
- aortic perfusion (1)
- aquaculture (1)
- artificial olfactory image (1)
- asymptotic relative efficiency (1)
- barium strontium titanate (1)
- biaxial tensile experiment (1)
- biomechanics (1)
- biosensor (1)
- biosensors (1)
- bootstrap (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- capacitive field-effect biosensor (1)
- capacitive field-effect sensor (1)
- carbonized rice husk (1)
- cardiomyocyte biomechanics (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- chemical sensor (1)
- chip-based sensor setup (1)
- cholera toxin B (1)
- cognitive impairment (1)
- community dwelling (1)
- complete block symmetry (1)
- computational fluid dynamics analysis (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- dental trauma (1)
- dialysis (1)
- difficult airway (1)
- distance learning (1)
- distorted element (1)
- double-lumen tube intubation (1)
- drinking water safety (1)
- drop jump (1)
- e-books (1)
- e-issues (1)
- efficiency (1)
- eigensolvers (1)
- elastic scattering (1)
- electrical conductivity of liquids (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electromyography (1)
- electronic nose (1)
- endoluminal (1)
- endospores (1)
- energy absorption (1)
- energy dissipation (1)
- enzymatic (bio)degradation (1)
- enzyme cascade (1)
- enzyme immobilization (1)
- exchangeability test (1)
- extracorporeal membrane oxygenation (1)
- fibulare Bandruptur (1)
- field-effect structure (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- frequency mixing (1)
- functional data (1)
- gait (1)
- gas sensor (1)
- glucose oxidase (GOx) (1)
- goodness-of-fit test (1)
- healthy aging (1)
- heavy metals (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- high-k material (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- humic acid (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- immobilization (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- independence test (1)
- intraclass correlation coefficient (1)
- key performance indicators (1)
- krypton xenon hydrate (1)
- lable-free detection (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- lignite (1)
- limit analysis (1)
- lipopolysaccharide (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic frequency mixing technique (1)
- magnetic nanoparticles (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- mechanical buffer (1)
- metal-oxide-semiconductor structure (1)
- method of fundamental solutions (1)
- microfluidics (1)
- micromagnetic simulation (1)
- multi-functional material (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- non-simplex S-FEM elements (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organosilanes (1)
- overload (1)
- parabolic flight (1)
- performance analysis (1)
- performance testing (1)
- physiology (1)
- plant virus detection (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- portfolio risk (1)
- prevention (1)
- psychosocial (1)
- random effects (1)
- random effects meta-regression model (1)
- rehabilitation (1)
- reliability of structures (1)
- retinal microvasculature (1)
- retinal vessels (1)
- running (1)
- rupture of the fibular ligament (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- sensors (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- shakedown analysis (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- smooth muscle contraction (1)
- softs (1)
- spatial resolution (1)
- sprint start (1)
- standard error of measurement (1)
- sterilisation (1)
- sterilization (1)
- sterilization conditions (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- surface modification (1)
- survival (1)
- temperature (1)
- tendon rupture (1)
- test-retest reliability (1)
- testing hypotheses (1)
- thermometry (1)
- tilted constant illumination (1)
- training simulator (1)
- tri-lineage differentiation (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual reality (1)
- viscoelasticity (1)
- visualization (1)
- walking (1)
- walking gait (1)
- · Psychiatrische Erkrankungen/Diagnostik (1)
A 2nd generation high performance small animal PET scanner, called ClearPET™, has been designed and a first prototype is built by working groups of the Crystal Clear Collaboration (CCC). In order to achieve high sensitivity and maintain good uniform spatial resolution over the field of view in high resolution PET systems, it is necessary to extract the depth of interaction (DOI) information and correct for spatial degradation. The design of the first ClearPET™ Demonstrator based on the use of the multi-anode photomultiplier tube (Hamamatsu R7600-M64) and a LSO/LuYAP phoswich matrix. The two crystal layers of 8*8 crystals (2*2*10 mm3) are stacked on each other and mounted without light guide as one to one on the PMT. A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the crystal ring is 137 mm, the axial detector length is 110 mm. The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. The measurements have been done using the first LSO/LuYAP detector cassettes.
The ClearPET™ project: Development of a 2nd generation high-performance small animal PET scanner
(2005)
Second generation high-performance PET scanners, called ClearPET™1, have been developed by working groups of the Crystal Clear Collaboration (CCC). High sensitivity and high spatial resolution for the ClearPET camera is achieved by using a phoswich arrangement combining two different types of lutetium-based scintillator materials: LSO from CTI and LuYAP:Ce from the CCC (ISTC project). In a first ClearPET prototype, phoswich arrangements of 8×8 crystals of 2×2×10 mm3 are coupled to multi-channel photomultiplier tubes (Hamamatsu R7600). A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the ring is 120 mm, the axial detector length is 110 mm.The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the exact pulse starting time, which is subsequently used for coincidence detection. The gantry allows rotation of the detector modules around the field of view.
Preliminary data shows a correct identification of the crystal layer about (98±1)%. Typically the energy resolution is (23.3±0.5)% for the luyap layer and (15.4±0.4)% for the lso layer. early studies showed the timing resolution of 2 ns FWHM and 4.8 ns FWTM. the intrinsic spatial resolution ranges from 1.37 mm to 1.61 mm full-width of half-maximum (FWHM) with a mean of 1.48 mm FWHM. further improvements in image and energy resolution are expected when the system geometry is fully modeled.
Beyond ClearPET: Next Aims
(2008)
The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET.
The ClearPET™ project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2nd generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET™ camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0% the simulated intrinsic resolution is about (1.41±0.11)mm compared to the measured of (1.48±0.06)mm. The simulated sensitivity profiles show a mean square deviation of 12.6% in axial direction and 3.6% in radial direction. Satisfactorily these results are representative for all designs and confirm the scanner geometry.
Recognition of subjects with mild cognitive impairment (MCI) by the use of retinal arterial vessels.
(2019)
Extracellular acidification is a basic indicator for alterations in two vital metabolic pathways: glycolysis and cellular respiration. Measuring these alterations by monitoring extracellular acidification using cell-based biosensors such as LAPS plays an important role in studying these pathways whose disorders are associated with numerous diseases including cancer. However, the surface of the biosensors must be specially tailored to ensure high cell compatibility so that cells can represent more in vivo-like behavior, which is critical to gain more realistic in vitro results from the analyses, e.g., drug discovery experiments. In this work, O2 plasma patterning on the LAPS surface is studied to enhance surface features of the sensor chip, e.g., wettability and biofunctionality. The surface treated with O2 plasma for 30 s exhibits enhanced cytocompatibility for adherent CHO–K1 cells, which promotes cell spreading and proliferation. The plasma-modified LAPS chip is then integrated into a microfluidic system, which provides two identical channels to facilitate differential measurements of the extracellular acidification of CHO–K1 cells. To the best of our knowledge, it is the first time that extracellular acidification within microfluidic channels is quantitatively visualized as differential (bio-)chemical images.