Refine
Year of publication
- 2020 (171) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (57)
- IfB - Institut für Bioengineering (33)
- Fachbereich Luft- und Raumfahrttechnik (30)
- Fachbereich Energietechnik (25)
- Fachbereich Elektrotechnik und Informationstechnik (20)
- ECSM European Center for Sustainable Mobility (14)
- Fachbereich Maschinenbau und Mechatronik (11)
- Fachbereich Wirtschaftswissenschaften (11)
- INB - Institut für Nano- und Biotechnologien (11)
- Fachbereich Chemie und Biotechnologie (10)
Language
- English (171) (remove)
Document Type
- Article (101)
- Conference Proceeding (46)
- Part of a Book (16)
- Book (2)
- Conference Poster (2)
- Doctoral Thesis (2)
- Conference: Meeting Abstract (1)
- Other (1)
Keywords
- MINLP (3)
- Additive manufacturing (2)
- Adjacent buildings (2)
- Experimental validation (2)
- Historical centres (2)
- Shake table test (2)
- Stone masonry (2)
- rebound-effect (2)
- sustainability (2)
- 3D printing (1)
- Acceptance (1)
- Adaptive control (1)
- Atmospheres (1)
- Biofuel (1)
- Biorefinery (1)
- Blind prediction competition (1)
- Brownian Pillow (1)
- Bumblebees (1)
- Butanol (1)
- Capacity Building Higher Education (1)
- Capacity Curve (1)
- Case study (1)
- Change culture (1)
- Clostridium acetobutylicum (1)
- Conservation laws (1)
- Cooling system (1)
- Crámer–von-Mises distance (1)
- Digital manufacturing (1)
- Digitalization (1)
- Dimensional splitting (1)
- Efficiency optimization (1)
- Engineering optimisation (1)
- Engineering optimization (1)
- Entropy solution (1)
- Ethics (1)
- European Framework and South East Asia (1)
- Exoplanet (1)
- Exponential time differencing (1)
- Finite difference methods (1)
- Flight control (1)
- Glass powder (1)
- Higher-order codes (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Human Development Index (1)
- Human factors (1)
- Human-robot collaboration (1)
- INODIS (1)
- Implicit methods (1)
- Incomplete data (1)
- Industrial optimisation (1)
- Interactive process mining (1)
- Interior transmission eigenvalues (1)
- Iterative learning control (1)
- L-PBF (1)
- Laser processing (1)
- Lean thinking (1)
- Lignocellulose (1)
- MAV (1)
- MILP (1)
- Malaysian Automotive Industry (1)
- Marginal homogeneity test (1)
- Masonry structures (1)
- Matrix exponential (1)
- Melting (1)
- Methodology (1)
- Mixed-integer programming (1)
- Monotone methods (1)
- Multi-dimensional partial differential equations (1)
- Neo-Deterministic (1)
- Network design (1)
- Nonlinear PDEs (1)
- OR 2019 (1)
- Objective data (1)
- Obstacle avoidance (1)
- Paired sample (1)
- Payload (1)
- Piecewise linearization (1)
- Powertrain (1)
- Process engineering (1)
- Pumping systems (1)
- Rapid manufacturing (1)
- Rapid prototyping (1)
- Reaction-diffusion systems (1)
- Real distinct pole (1)
- Resampling test (1)
- Resilience assessment (1)
- Resilience metric graph theory (1)
- Resilient infrastructure (1)
- Robotic rehabilitation (1)
- SSE) JEL : O33 (1)
- Seismic Hazard (1)
- Source term (1)
- Spectroscopy (1)
- Technical Operations Research (1)
- Technology Transfer (1)
- Transit (1)
- UAV (1)
- Vulnerability Curves (1)
- Water distribution system (1)
- Water supply system (1)
- agility (1)
- anticipation strategy (1)
- automotive (1)
- business analytics (1)
- community dwelling (1)
- connection detail (1)
- corporate sustainability (1)
- critical (1)
- decision analytics (1)
- digital economy (1)
- digital twin (1)
- earthquake (1)
- efficiency side-effects (1)
- elastic scattering (1)
- fault detection (1)
- grey energy (1)
- healthy aging (1)
- in-plane (1)
- industry 4.0 (1)
- jevons paradox (1)
- literature (1)
- marketing (1)
- mathematical optimization (1)
- method of fundamental solutions (1)
- not identically distributed (1)
- out-of-plane (1)
- prevention (1)
- psychosocial (1)
- random effects meta-regression model (1)
- resource abundance (1)
- review (1)
- socio-economic welfare (1)
- systematic (1)
- water supply system (1)
Is part of the Bibliography
- no (171)
This paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs dramatically. As the Human Development Index provides insight into a country’s cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. The hypothesis presented and discussed in this paper was researched before. A qualitative research approach was used in the author’s master’s thesis “The Human Development Index (HDI) as a Reflection of Resource Abundance (using Nigeria and Norway as a case study)” in 2018. The management of scarce resources is an important aspect in the development of modern countries and those on the threshold of becoming industrialised nations. The effects of a mistaken resource management are not only of a purely economic nature but also of a social and socio-economic nature. In order to present a partial aspect of these dependencies and influences this paper uses a quantitative analysis to examine the interdependence and impact of resource rents on socio-economic development from 2002 to 2017. Nigeria and Norway have been chosen as reference countries due to their abundance of natural resources by similar economic performance, while the ranking in the Human Development Index differs significantly. As the Human Development Index provides insight into a country’s cultural and socio-economic characteristics and development in addition to economic indicators, it allows a comparison of the two countries. This paper found out in a holistic perspective that (not or poorly managed) resource wealth in itself has a negative impact on socio-economic development and significantly reduces the productivity of the citizens of a state. This is expressed in particular for the years 2002 till 2017 in a negative correlation of GDP per capita and HDI value with the share respectively the size of resources in the GDP of a country.
Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model
(2020)
Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5% and 50nM verapamil by 2,8%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis.
The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.
Producing fresh water from saline water has become one of the most difficult challenges to overcome especially with the high demand and shortage of fresh water. In this context, as part of a collaboration with Germany, the authors propose a design and implementation of a pilot multi-stage solar desalination system (MSD), remotely controlled, at Douar Al Hamri in the rural town of Boughriba in the province of Berkane, Morocco. More specifically, they present their contribution on the remote control and supervision system, which makes the functioning of the MSD system reliable and guarantees the production of drinking water for the population of Douar. The results obtained show that the electronic cards and computer communication software implemented allow the acquisition of all electrical (currents, voltages, powers, yields), thermal (temperatures of each stage), and meteorological (irradiance and ambient temperature), remote control and maintenance (switching on, off, data transfer). By comparing with the literature carried out in the field of solar energy, the authors conclude that the MSD and electronic desalination systems realized during this work represent a contribution in terms of the reliability and durability of providing drinking water in rural and urban areas.
A second-order L-stable exponential time-differencing (ETD) method is developed by combining an ETD scheme with approximating the matrix exponentials by rational functions having real distinct poles (RDP), together with a dimensional splitting integrating factor technique. A variety of non-linear reaction-diffusion equations in two and three dimensions with either Dirichlet, Neumann, or periodic boundary conditions are solved with this scheme and shown to outperform a variety of other second-order implicit-explicit schemes. An additional performance boost is gained through further use of basic parallelization techniques.
The treatment of septic wounds with curative dressings based on biocomposites containing sage and marigold phytoextracts was effective in in vitro and in vivo experiments. These dressings caused the purification of the wound surface from purulent-necrotic masses three days earlier than in the other experimental groups. The consequence of an increase in incidents of severe course of the wound and the observed tendency to increase the number of adverse effects is the development of long-term recurrent wound processes. To treat purulent wounds, the following tactics were used: The purulent wounds of animals were covered with the examined wound dressing, and then the next day samples were taken, the procedure was performed once in 2 days. To obtain the active nanostructured sorbents such as carbonized rice husks, they are functionalized with biologically active components possessing antimicrobial, anti-inflammatory, antitoxic, immunomodulating, antiallergic and other types of properties.
Humic substances originating from various organic matters can ameliorate soil properties, stimulate plant growth, and improve nutrient uptake. Due to the low calorific heating value, leonardite is rather unsuitable as fuel. However, it may serve as a potential source of humic substances. This study was aimed at characterizing the leonardite-based soil amendments and examining the effect of their application on the soil microbial community, as well as on potato growth and tuber yield. A high yield (71.1%) of humic acid (LHA) from leonardite has been demonstrated. Parental leonardite (PL) and LHA were applied to soil prior to potato cultivation. The 16S rRNA sequencing of soil samples revealed distinct relationships between microbial community composition and the application of leonardite-based soil amendments. Potato tubers were planted in pots in greenhouse conditions. The tubers were harvested at the mature stage for the determination of growth and yield parameters. The results demonstrated that the LHA treatments had a significant effect on increasing potato growth (54.9%) and tuber yield (66.4%) when compared to the control. The findings highlight the importance of amending leonardite-based humic products for maintaining the biogeochemical stability of soils, for keeping their healthy microbial community structure, and for increasing the agronomic productivity of potato plants.
There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords “vitamin D,” “intestines,” “gut microflora,” “bowel inflammation”. Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.
We present new numerical results for shape optimization problems of interior Neumann eigenvalues. This field is not well understood from a theoretical standpoint. The existence of shape maximizers is not proven beyond the first two eigenvalues, so we study the problem numerically. We describe a method to compute the eigenvalues for a given shape that combines the boundary element method with an algorithm for nonlinear eigenvalues. As numerical optimization requires many such evaluations, we put a focus on the efficiency of the method and the implemented routine. The method is well suited for parallelization. Using the resulting fast routines and a specialized parametrization of the shapes, we found improved maxima for several eigenvalues.
Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed.