Refine
Year of publication
Document Type
- Article (5586)
- Conference Proceeding (1620)
- Book (1078)
- Part of a Book (548)
- Bachelor Thesis (297)
- Patent (172)
- Report (100)
- Doctoral Thesis (78)
- Other (77)
- Administrative publication (76)
- Part of Periodical (63)
- Lecture (30)
- Master's Thesis (20)
- Contribution to a Periodical (19)
- Review (17)
- Diploma Thesis (15)
- Working Paper (13)
- Course Material (9)
- Talk (7)
- Study Thesis (5)
Language
- German (5012)
- English (4801)
- Russian (14)
- Portuguese (6)
- Multiple languages (5)
- Spanish (3)
- nld (2)
- Italien (1)
Keywords
- Amtliche Mitteilung (71)
- Bachelor (33)
- Aachen University of Applied Sciences (31)
- Master (31)
- Prüfungsordnung (31)
- Bauingenieurwesen (30)
- Lesbare Fassung (28)
- Biosensor (25)
- Fachhochschule Aachen (23)
- Illustration (21)
- Studien- und Prüfungsordnung (21)
- Aachen / Fachhochschule Aachen (20)
- Änderungsordnung (20)
- Blitzschutz (18)
- Corporate Design (17)
- Elektromobilität (17)
- CAD (16)
- Finite-Elemente-Methode (16)
- Fotografie (16)
- civil engineering (14)
Institute
- Fachbereich Medizintechnik und Technomathematik (2052)
- Fachbereich Elektrotechnik und Informationstechnik (1150)
- Fachbereich Wirtschaftswissenschaften (1138)
- Fachbereich Energietechnik (1104)
- Fachbereich Maschinenbau und Mechatronik (866)
- Fachbereich Chemie und Biotechnologie (847)
- Fachbereich Luft- und Raumfahrttechnik (776)
- Fachbereich Bauingenieurwesen (705)
- IfB - Institut für Bioengineering (686)
- INB - Institut für Nano- und Biotechnologien (613)
- Fachbereich Gestaltung (484)
- Solar-Institut Jülich (339)
- Fachbereich Architektur (174)
- FH Aachen (153)
- ECSM European Center for Sustainable Mobility (112)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (74)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (71)
- Nowum-Energy (70)
- Institut fuer Angewandte Polymerchemie (32)
- Sonstiges (24)
The light-addressable potentiometric sensor (LAPS) has the unique feature to address different regions of a sensor surface without the need of complex structures. Measurements at different locations on the sensor surface can be performed in a common analyte solution, which distinctly simplifies the fluidic set-up. However, the measurement in a single analyte chamber prevents the application of different drugs or different concentrations of a drug to each measurement spot at the same time as in the case of multi-reservoir-based set-ups. In this work, the authors designed a LAPS-based set-up for cell culture screening that utilises magnetic beads loaded with the endotoxin (lipopolysaccharides, LPS), to generate a spatially distributed gradient of analyte concentration. Different external magnetic fields can be adjusted to move the magnetic beads loaded with a specific drug within the measurement cell. By recording the metabolic activities of a cell layer cultured on top of the LAPS surface, this work shows the possibility to apply different concentrations of a sample along the LAPS measurement spots within a common analyte solution.
This work describes the novel combination of the light-addressable electrode (LAE) and the light-addressable potentiometric sensor (LAPS) into a microsystem set-up. Both the LAE as well as the LAPS shares the principle of addressing the active spot by means of a light beam. This enables both systems to manipulate resp. to detect an analyte with a high spatial resolution. Hence, combining both principles into a single set-up enables the active stimulation e.g., by means of electrolysis and a simultaneous observation e.g., the response of an entrapped biological cell by detection of extracellular pH changes. The work will describe the principles of both technologies and the necessary steps to integrate them into a single set-up. Furthermore, examples of application and operation of such systems will be presented.
Handheld measurement device for field-effect sensor structures: Practical evaluation and limitations
(2007)
Online-Messsysteme für die automatisierte Charakterisierung von feldeffektbasierten Biosensoren
(2007)
We report on the synthesis and CO gas-sensing properties of mesoporous tin(IV) oxides (SnO2). For the synthesis cetyltrimethylammonium bromide (CTABr) was used as a structure-directing agent; the resulting SnO2 powders were applied as films to commercially available sensor substrates by drop coating. Nitrogen physisorption shows specific surface areas up to 160 m2·g-1 and mean pore diameters of about 4 nm, as verified by TEM. The film conductance was measured in dependence on the CO concentration in humid synthetic air at a constant temperature of 300 °C. The sensors show a high sensitivity at low CO concentrations and turn out to be largely insensitive towards changes in the relative humidity. We compare the materials with commercially available SnO2-based sensors.