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Brandes, Sinja ; Gligorevic, Snjezana ; Schnell, Michael ; Rokitansky, Carl-Herbert ; Ehammer, Max ; Gräupl, Thomas ; Schlereth, Armin ; Rihacek, Christoph
Es wird von Gleichungen ausgegangen, mit denen die Modellkoeffizienten von Regelstrecken mit Ausgleich aus der gemessenen Sprungantwort ermittelt werden können. Die Übertragungsfunktion der Regelstrecke hat einen konstanten Zähler und ein Nennerpolynom. Unter der Annahme, daß die ideale und exakte Sprungantwort des Systems durch ein stochastisches Signal gestört wird, wird untersucht, wie die Fehler der ermittelten Modellkoeffizienten von Kennwerten des Störsignals und von der Meßzeit für die Sprungantwort abhängen. Durch eine Simulation auf dem Digitalrechner wurden die Ergebnisse kontrolliert. Es zeigt sich, daß durch eine Filterung der gestörten Sprungantwort über einen Tiefpaß keine Verbesserung der Analyseergebnisse erreicht werden kann, da das Identifizierungsverfahren eine glättende Eigenschaft hat.
Maas, Marnix C. ; Vos, Eline K. ; Lagemaat, Miriam W. ; Bitz, Andreas ; Orzada, Stephan ; Kobus, Thiele ; Kraff, Oliver ; Maderwald, Stefan ; Ladd, Mark E. ; Scheenen, Tom W. J.
Purpose
To demonstrate that high quality T₂-weighted (T2w) turbo spin-echo (TSE) imaging of the complete prostate can be achieved routinely and within safety limits at 7 T, using an external transceive body array coil only.
Methods
Nine healthy volunteers and 12 prostate cancer patients were scanned on a 7 T whole-body system. Preparation consisted of B₀ and radiofrequency shimming and localized flip angle calibration. T₁ and T₂ relaxation times were measured and used to define the T2w-TSE protocol. T2w imaging was performed using a TSE sequence (pulse repetition time/echo time 3000–3640/71 ms) with prolonged excitation and refocusing pulses to reduce specific absorption rate.
Results
High quality T2w TSE imaging was performed in less than 2 min in all subjects. Tumors of patients with gold-standard tumor localization (MR-guided biopsy or prostatectomy) were well visualized on 7 T imaging (n = 3). The number of consecutive slices achievable within a 10-g averaged specific absorption rate limit of 10 W/kg was ≥28 in all subjects, sufficient for full prostate coverage with 3-mm slices in at least one direction.
Conclusion
High quality T2w TSE prostate imaging can be performed routinely and within specific absorption rate limits at 7 T with an external transceive body array.
Schlamann, Marc ; Voigt, Melanie A. ; Maderwald, Stefan ; Bitz, Andreas ; Kraff, Oliver ; Ladd, Susanne C. ; Ladd, Mark E. ; Forsting, Michael ; Wilhelm, Hans
Purpose
To assess potential cognitive deficits under the influence of static magnetic fields at various field strengths some studies already exist. These studies were not focused on attention as the most vulnerable cognitive function. Additionally, mostly no magnetic resonance imaging (MRI) sequences were performed.
Materials and Methods
In all, 25 right-handed men were enrolled in this study. All subjects underwent one MRI examination of 63 minutes at 1.5 T and one at 7 T within an interval of 10 to 30 days. The order of the examinations was randomized. Subjects were referred to six standardized neuropsychological tests strictly focused on attention immediately before and after each MRI examination. Differences in neuropsychological variables between the timepoints before and after each MRI examination were assessed and P-values were calculated
Results
Only six subtests revealed significant differences between pre- and post-MRI. In these tests the subjects achieved better results in post-MRI testing than in pre-MRI testing (P = 0.013–0.032). The other tests revealed no significant results.
Conclusion
The improvement in post-MRI testing is only explicable as a result of learning effects. MRI examinations, even in ultrahigh-field scanners, do not seem to have any persisting influence on the attention networks of human cognition immediately after exposure.
Reinhardt, T. ; Bitz, Andreas ; El Ouardi, A. ; Streckert, J. ; Sommer, A. ; Lerchl, A. ; Hansen, V.
Planning the layout and operation of a technical system is a common task
for an engineer. Typically, the workflow is divided into consecutive stages: First,
the engineer designs the layout of the system, with the help of his experience or of
heuristic methods. Secondly, he finds a control strategy which is often optimized
by simulation. This usually results in a good operating of an unquestioned sys-
tem topology. In contrast, we apply Operations Research (OR) methods to find a
cost-optimal solution for both stages simultaneously via mixed integer program-
ming (MILP). Technical Operations Research (TOR) allows one to find a provable
global optimal solution within the model formulation. However, the modeling error
due to the abstraction of physical reality remains unknown. We address this ubiq-
uitous problem of OR methods by comparing our computational results with mea-
surements in a test rig. For a practical test case we compute a topology and control
strategy via MILP and verify that the objectives are met up to a deviation of 8.7%.