Refine
Year of publication
- 2023 (256) (remove)
Institute
- Fachbereich Gestaltung (95)
- Fachbereich Medizintechnik und Technomathematik (39)
- Fachbereich Elektrotechnik und Informationstechnik (29)
- Fachbereich Luft- und Raumfahrttechnik (24)
- ECSM European Center for Sustainable Mobility (23)
- Fachbereich Wirtschaftswissenschaften (21)
- Fachbereich Chemie und Biotechnologie (17)
- Fachbereich Energietechnik (14)
- INB - Institut für Nano- und Biotechnologien (12)
- Fachbereich Maschinenbau und Mechatronik (10)
Document Type
- Bachelor Thesis (93)
- Article (77)
- Conference Proceeding (36)
- Part of a Book (22)
- Book (11)
- Patent (3)
- Habilitation (2)
- Master's Thesis (2)
- Preprint (2)
- Talk (2)
Keywords
- Corporate Design (6)
- Editorial (6)
- Illustration (6)
- Typografie (6)
- Nachhaltigkeit (5)
- Produktdesign (5)
- Fotografie (4)
- Publikation (4)
- Design (3)
- Erscheinungsbild (3)
- Information extraction (3)
- Kinder (3)
- Künstliche Intelligenz (3)
- Museum (3)
- Natural language processing (3)
- nachhaltig (3)
- Animation (2)
- Architektur (2)
- Associated liquids (2)
- Bacillaceae (2)
- Biotechnological application (2)
- CFD (2)
- Datenvisualisierung (2)
- Diversity Management (2)
- Editorial Design (2)
- Engineering Habitus (2)
- Familie (2)
- Future Skills (2)
- Graphic Novel (2)
- Industriedesign (2)
- Informationsdesign (2)
- Inklusion (2)
- Interdisciplinarity (2)
- Kampagne (2)
- Keramik (2)
- Kommunikation (2)
- Kommunikationsdesign (2)
- Lernen (2)
- Licht (2)
- Magazin (2)
- Medienkompetenz (2)
- Modular (2)
- Musik (2)
- Organizational Culture (2)
- Power plants (2)
- Print (2)
- Redesign (2)
- Sammlung (2)
- Sport (2)
- Subtilases (2)
- Subtilisin (2)
- Sustainability (2)
- additive manufacturing (2)
- factory planning (2)
- interaktiv (2)
- manufacturing flexibility (2)
- ultrasound (2)
- (Poly)saccharides (1)
- (R)- or (S)- gamma-valerolactone (1)
- 197m/gHg (1)
- 2D (1)
- 3D Scan (1)
- 4-hydroxy valeric acid (1)
- 60er Jahre (1)
- Abenteuer (1)
- Abgelegene Gebiete (1)
- Abstrahierung (1)
- Abstrakt (1)
- Abwechslung (1)
- Academia (1)
- Active learning (1)
- Acyl-amino acids (1)
- Aeroelasticity (1)
- Agent-based simulation (1)
- Agile development (1)
- Algen (1)
- Aloe vera (1)
- Alternative Konsumoption (1)
- Aminoacylase (1)
- Amtliche Mitteilungen (1)
- Analoge und Digitale Welt (1)
- Anammox (1)
- Android (1)
- Angststörungen (1)
- Anomaly detection (1)
- Antennen (1)
- Anti-Bias (1)
- Antibias (1)
- Arbeitsbekleidung (1)
- Architectural design (1)
- Asymptotic relative efficiency (1)
- Atmen (1)
- Aufklärung (1)
- Aufklärungskampagne (1)
- Ausstellungsdesign (1)
- Ausstellungskonzept (1)
- Automation (1)
- Automobil (1)
- Automotive safety approach (1)
- Autonomy (1)
- BMW (1)
- Bachelor (1)
- Bacillus atrophaeus spores (1)
- Bacterial cellulose (1)
- Bahn (1)
- Bahnfahrt (1)
- Bambus (1)
- Barock (1)
- Benin Bronzen (1)
- Benutzerfreundlich (1)
- Berlin (1)
- Best practice sharing (1)
- Bewegtbild (1)
- Bewegung (1)
- Bioabsorbable (1)
- Bioenergiefassaden (1)
- Blade element method (1)
- Blindenstock (1)
- Blog (1)
- Blütenkelch (1)
- Bookazine (1)
- Bragg peak (1)
- Brake set-up (1)
- Braking curves (1)
- Branding (1)
- Brands (1)
- Broad pH spectrum (1)
- Broschüre (1)
- Building Automation (1)
- Business Process Intelligence (1)
- CO2 (1)
- CO2 emission reduction targets (1)
- CPQ (1)
- CRISPR/Cas9 (1)
- Capacitive field-effect sensor (1)
- Carbon Dioxide (1)
- Carbon sources (1)
- Cellulose nanostructure (1)
- Change (1)
- Chaperone co-expression (1)
- Charging station (1)
- Chiralidon-R (1)
- Chiralidon-S (1)
- Chondroitin sulfate (1)
- Clustering (1)
- Cognitive assistance system (1)
- Competitiveness (1)
- Computerspiel (1)
- Conductive Boundary Condition (1)
- Connected Automated Vehicle (1)
- Control (1)
- Corporatedesign (1)
- Cost function (1)
- Cost-effectiveness (1)
- Cramér-von-Mises test (1)
- Crashworthiness (1)
- Cross border adjustment mechanism (1)
- Culture media (1)
- Cyclotron production (1)
- DPA (dipicolinic acid) (1)
- Daniele Ganser (1)
- Datasets (1)
- Datenschutzgrundverordnung (1)
- Decision theory (1)
- Deep learning (1)
- Depressionen (1)
- Design Thinking (1)
- Dienstplanung (1)
- Dietary supplements (1)
- Digital (1)
- Digital leadership (1)
- Digital transformation (1)
- Digital triage (1)
- Digital twin (1)
- Digitales Lernen (1)
- Diskurs (1)
- Diskussionskarten (1)
- Distinktion (1)
- District data model (1)
- District energy planning platform (1)
- Dokumentarfilm (1)
- Dokumentarfotografie (1)
- Dokumentation (1)
- Drag estimation (1)
- Driver assistance system (1)
- Driving cycle recognition (1)
- Dänisch (1)
- E-Mobility (1)
- ECMS (1)
- EMS (1)
- Earthquake (1)
- Editorail Design (1)
- Editorial-Design (1)
- Education (1)
- Effizienz (1)
- Einkaufen (1)
- Eisenerz (1)
- Eishockey (1)
- Electrocardiography (1)
- Electrochemistry (1)
- Electronic vehicle (1)
- Elektrotechnik (1)
- Elicit (1)
- Eltern (1)
- Emotionen (1)
- Endometriose (1)
- Endothelial dysfunction (1)
- Energiemanagement (1)
- Energy Disaggregation (1)
- Energy management strategies (1)
- Energy market design (1)
- Energy storage (1)
- Energy system planning (1)
- Energy-intensive industry (1)
- Enma (1)
- Entdecken (1)
- Enterprise information systems (1)
- Erkunden (1)
- Erneuerbare Energien (1)
- Erweiterbar (1)
- Experimentalfilm (1)
- Experimente (1)
- Experteninterviews (1)
- Expertise (1)
- FH Aachen (1)
- Fahrzeug (1)
- Familienkasse (1)
- Fan-Kultur (1)
- Fans (1)
- Farbe (1)
- Farbwechsel (1)
- Fassadenverkleidung (1)
- Fault approximation (1)
- Fault detection (1)
- Feldsimulation (1)
- Fenster (1)
- Finite element method (1)
- Finland (1)
- Fliesen (1)
- Floor prices (1)
- Flut (1)
- Flächennutzung (1)
- Formel 1 (1)
- Fotoinstallation (1)
- Frau (1)
- Freight rail (1)
- Freiheit (1)
- Full-vehicle crash test (1)
- Future skills (1)
- Fußball (1)
- Fußballtrikot (1)
- Ga-68 (1)
- Gamification (1)
- Gaming Maus (1)
- Gaming Produkte (1)
- Gefahr (1)
- Gehirn (1)
- Gemüse (1)
- Generative Gestaltung (1)
- Generatives Design (1)
- Geometrisch (1)
- Geriatric (1)
- Germany (1)
- Gerüche (1)
- Gesellschaftskritik (1)
- Gesteine (1)
- Gesundheit (1)
- Gesundheitsförderung (1)
- GewohnheitDerHaltung (1)
- Glas (1)
- Glucosamine (1)
- Gold nanoparticle (AuNP) (1)
- Gold nanoparticles (1)
- Good News Fokus (1)
- Grabstaetten (1)
- Grafikdesign (1)
- Griechisch (1)
- Grotesk (1)
- Guide Tube (1)
- Habitate (1)
- Halotolerant protease (1)
- Haltung (1)
- Haltungsschwäche (1)
- Handwerk (1)
- Hardcase (1)
- Haushaltsgerät (1)
- Hebamme (1)
- Heimat (1)
- High-field NMR (1)
- Hindernisse (1)
- Hip fractures (1)
- Historie (1)
- Hochfrequenztechnik (1)
- Hochwasserkatastrophe (1)
- Holzverbindungen (1)
- Home Assistant (1)
- Home Automation Platform (1)
- Human factors (1)
- Human-centered work design (1)
- Human-robot collaboration (1)
- ITFS (1)
- Ice melting probe (1)
- Ice penetration (1)
- Icy moons (1)
- Identifikation (1)
- Inclusion bodies (1)
- Incomplete data (1)
- Informationsfluss (1)
- Inklusiv (1)
- Innovation (1)
- Instagram store (1)
- Installation (1)
- Interaktive Gestaltung (1)
- Interculturality (1)
- Interessen (1)
- Interview (1)
- Intuitiv (1)
- Inverse Scattering (1)
- Inverse scattering problem (1)
- Iran (1)
- J.R.R Tolkien (1)
- Japan (1)
- Juli21 (1)
- KI (1)
- KI Kunst (1)
- Key competences (1)
- Kind (1)
- Kindererziehung (1)
- Kinderfahrrad (1)
- Kindheit (1)
- Klassische Musik (1)
- Klassizismus (1)
- Klettern (1)
- Klimakrise (1)
- Kochen (1)
- Konkurrenz (1)
- Konservierung (1)
- Kontaktabbruch (1)
- Konzerthaus (1)
- Kooperation (1)
- Krankheit (1)
- Kreativer Bildungsweg (1)
- Kreativität (1)
- Krebs (1)
- Krise (1)
- Kulturgut (1)
- Kunst (1)
- Kunstsammlung (1)
- Kurzfilme (1)
- Küche (1)
- Künstliche Intelligenz (KI) (1)
- Label-free detection (1)
- Labyfrinth weirs (1)
- Lactobacillus rhamnosus GG (1)
- Lampe (1)
- Landwirt (1)
- Landwirtschaft (1)
- Large Eddy Simulation (1)
- Latentes Wasser (1)
- Latvia (1)
- LbL films (1)
- Leaderboard (1)
- Leben (1)
- Lebensmittel (1)
- Leichen (1)
- Leitfaden (1)
- Lesesessel (1)
- Letraset (1)
- Leuchte (1)
- Levulinic acid (1)
- Lichtkunst (1)
- Lichtkunst Museum (1)
- Linkshändigkeit (1)
- Livestream (1)
- Local path planning (1)
- Lokal (1)
- Long COVID (1)
- Luftreiniger (1)
- Luxury (1)
- MCDA (1)
- Machine Learning (1)
- Mainstream (1)
- Marginal homogeneity (1)
- Market modeling (1)
- Mars (1)
- Masonry partition walls (1)
- Medical radionuclide production (1)
- Medien (1)
- Medienjournalist (1)
- Medienscouts (1)
- Medizindesign (1)
- Medusomyces gisevi (1)
- Meere (1)
- Meitner-Auger-electron (MAE) (1)
- Menschen (1)
- Mental Health (1)
- Metal contaminants (1)
- Microfluidic solvent extraction (1)
- Micromix (1)
- Mineral (1)
- Mineralien (1)
- Minimalismus (1)
- Minimum Risk Manoeuvre (1)
- Minor chemistry (1)
- Mittelalter (1)
- Mobil (1)
- Mobility transition (1)
- Mobilität (1)
- Model-driven software engineering (1)
- Modernität (1)
- Modularität (1)
- Modulbau (1)
- Monster (1)
- Motivation (1)
- Mpc (1)
- Multi-criteria decision analysis (1)
- Multi-objective optimization (1)
- Multicell (1)
- Multimedia (1)
- Multiplexing (1)
- Multirotor UAS (1)
- Mutter (1)
- Männlichkeit (1)
- Nachhaltig (1)
- Nahrung (1)
- Narzissmus (1)
- Natur (1)
- Natural Language Processing (1)
- Natural language understanding (1)
- Navigation (1)
- Neue Arbeitsweise (1)
- Neugestaltung (1)
- Neural networks (1)
- Nitrogen removal (1)
- Nozzle (1)
- Obstacle avoidance (1)
- Ocean worlds (1)
- Office (1)
- Online-Radikalisierung (1)
- Onlinehandel (1)
- Onlinepräsenz (1)
- Open Educational Resources (OER) (1)
- Open Source (1)
- OpenEMS (1)
- Operational Design Domain (1)
- Operations (1)
- Optimierung (1)
- Organic acids (1)
- Out-of-plane capacity (1)
- Ozean (1)
- PLS (1)
- Paired sample (1)
- Parking (1)
- Partial nitritation (1)
- Path planning (1)
- Path-following (1)
- Pendelleuchte (1)
- Pendelnde (1)
- Performance (1)
- Personality (1)
- Perspektive (1)
- Pflanzenteile (1)
- Philipp Hübl (1)
- Physical chemistry (1)
- Physical chemistry basics (1)
- Physical chemistry starters (1)
- Pix2Pix (1)
- Pizza (1)
- Plakat (1)
- Plasmatechnik (1)
- Politik (1)
- Polster (1)
- Polylactide acid (1)
- Polysaccharides (1)
- Portalrahmen (1)
- Portrait (1)
- Positives Feedback (1)
- Post-COVID-19 syndrome (1)
- Predictive battery discharge (1)
- Preference assessment (1)
- Prevention (1)
- Privacy (1)
- Process Model Extraction (1)
- Process optimization (1)
- Produkt Design (1)
- Produktion (1)
- Profile extraction (1)
- Propeller (1)
- Propeller elasticity (1)
- Prophylaxis (1)
- Prototype (1)
- Prozessauswahl (1)
- Prozessautomatisierung (1)
- Prozessverbesserung (1)
- Prävention (1)
- Prüfungsordnung (1)
- Psychologie (1)
- Psychotherapie (1)
- Quality control (1)
- Quelle-Fertighaus (1)
- Query learning (1)
- RWTH Aachen (1)
- Rabbit Hole (1)
- Raman spectroscopy (1)
- Raumatmosphäre (1)
- Regalsystem (1)
- Regie (1)
- Regionalization (1)
- Rehabilitaion (1)
- Relation classification (1)
- Renewable energy integration (1)
- Reproducible research (1)
- Reservation system (1)
- Resistive temperature detector (1)
- Responsibility (1)
- Ressourcenschonung (1)
- Restaurierung (1)
- Revolution (1)
- Riten (1)
- Rivalität (1)
- Robotic Process Automation (1)
- Rotary encoder (1)
- Rotring (1)
- Router (1)
- Roverandom (1)
- Rucksack (1)
- Ruhe (1)
- Rückgabe (1)
- Rüster (1)
- SOA (1)
- Sachbuch (1)
- Schadensersatz (1)
- Schattenseite (1)
- Schauspiel (1)
- Schauspielhaus (1)
- Schein (1)
- Schichtarbeit (1)
- Schlafstörungen (1)
- Schlepper (1)
- Schlüter (1)
- Schraffur (1)
- Schriftvarianten (1)
- Schönheit (1)
- Seamlessconnection (1)
- Seepferdchen (1)
- Sehbehinderung (1)
- Selbstzensur (1)
- Selektionskriterien (1)
- Sendungskonzeption (1)
- Sensors comparison (1)
- Serie (1)
- Sharing (1)
- Shiba Inu (1)
- Shunting (1)
- Siebdruck (1)
- Siegerland (1)
- Silk fibroin (1)
- Simulation (1)
- Skandinavien (1)
- Slab deflection (1)
- Smart Building (1)
- Smart-Home (1)
- Smarthome (1)
- Smartwatch (1)
- Sn₃O₄ (1)
- Social Media Kampagne (1)
- Social impact measurement (1)
- Society (1)
- Software (1)
- Software and systems modeling (1)
- Software development (1)
- Software testing (1)
- Softwareentwicklung (1)
- Solarenergie (1)
- Sonderausstellung (1)
- Sonderzeichen (1)
- Soziale Medien (1)
- Sozialer Wohnungsbau (1)
- Sozialleistungen (1)
- Spectroscopy (1)
- Spezies (1)
- Spiele (1)
- Stadt Aachen (1)
- Stahlkonstruktion (1)
- Start-up (1)
- Starterkit (1)
- Steckverbindung (1)
- Steel industry (1)
- Storytelling (1)
- Streptomyces griseus (1)
- Streptomyces lividans (1)
- Stress (1)
- Stress testing (1)
- Stuhl (1)
- Stuttgart (1)
- Suction (1)
- Sustainable engineering education (1)
- TICTOP (1)
- Tanz (1)
- Targeted radionuclide therapy (TRT) (1)
- Tauchboot (1)
- Teamwork (1)
- Technologie (1)
- Telefonat (1)
- Text Mining (1)
- Text mining (1)
- Theater (1)
- Therapeutensuche (1)
- Therapieplatzsuche (1)
- Thermodynamics as minor (1)
- Tiere (1)
- Time-series synchronization (1)
- Tochter (1)
- Tod (1)
- Toolbar (1)
- Traktor (1)
- Transdisciplinarity (1)
- Transformative Competencies (1)
- Transiton of Control (1)
- Transkulturen (1)
- Transmission Eigenvalues (1)
- Triage-app (1)
- Trickfilm-Festival (1)
- Trikot (1)
- Trustworthy artificial intelligence (1)
- UAV (1)
- UI (1)
- UI Design (1)
- UI/UX-Design (1)
- UX (1)
- UX Design (1)
- UX-Design (1)
- Unterstützung (1)
- Unterwasserwelt (1)
- Urbane Gestaltung (1)
- Urbanisierung (1)
- Usability (1)
- Utilization improvement (1)
- V2X (1)
- Variable Schriften (1)
- Vater (1)
- Verschwörungstheorien (1)
- Verwesung (1)
- Vibrio natriegens (1)
- Virtuelles Wasser (1)
- Visuelle Gestaltung (1)
- Voltfang (1)
- Volumes of confidence regions (1)
- Wallrafmuseum (1)
- Wandverkleidung (1)
- Waschmaschine (1)
- Wasserknappheit (1)
- Wastewater (1)
- Wattenmeer (1)
- Wearable electronic device (1)
- Weiterentwicklung (1)
- Werkstatt (1)
- Werkzeuge (1)
- WiLMo (1)
- Wiegand sensor (1)
- Wifi (1)
- Wind milling (1)
- Wind tunnel experiments (1)
- Windkraft (1)
- Wirtschaftsinformatik (1)
- Wissensvermittlung (1)
- Work-Life-Balance (1)
- Workaholic (1)
- Wortmarke (1)
- Zeit (1)
- Zen (1)
- Zensur (1)
- Zoo (1)
- Zug (1)
- active learning (1)
- adaptive systems (1)
- aircraft engine (1)
- allocation (1)
- amperometric biosensors (1)
- analog (1)
- anammox (1)
- artificial intelligence (1)
- aspergillus (1)
- assistance system (1)
- audiovisuell (1)
- auswechseln (1)
- bacterial cellulose (1)
- bio-methane (1)
- biocompatible (1)
- biodegradabl (1)
- biofilms (1)
- biological dosimeter (1)
- biomechanics (1)
- biosensor (1)
- bubble column (1)
- central symmetry test (1)
- children (1)
- climate change (1)
- combustion (1)
- compression behavior (1)
- conceptual design (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- covariance principle (1)
- deficit irrigation (1)
- distribution grid simulation (1)
- e-mobility (1)
- eVTOL development (1)
- eVTOL safety (1)
- electromyography (1)
- emission index (1)
- encapsulation materials (1)
- energy efficiency (1)
- entrepreneurship education (1)
- entspannen (1)
- enzyme cascade (1)
- exchangeability test (1)
- fibroin (1)
- field-effect sensor (1)
- filamentous fungi (1)
- forecast (1)
- fuel cell vehicle (1)
- fused filament fabrication (1)
- gamification (1)
- gendern (1)
- genome engineering (1)
- glucose oxidase (GOx) (1)
- goodness-of-fit test (1)
- heavy metals (1)
- horseradish peroxidase (HRP) (1)
- hydrogel (1)
- hydrogen (1)
- immobilization (1)
- independence test (1)
- industrial design (1)
- infill strategy (1)
- intelligent control (1)
- intelligent energy management (1)
- klimakrise (1)
- klimawandel (1)
- lab work (1)
- locomotion (1)
- machine learning (1)
- mainstream deammonification (1)
- manufacturing (1)
- manufacturing data model (1)
- methanation (1)
- mix flexibility (1)
- modular (1)
- nachhaltiges Bauen (1)
- nanobelts (1)
- neutrons (1)
- niedlich (1)
- nitric oxides (1)
- nitrogen elimination (1)
- not identically distributed (1)
- onion (1)
- optical fibers (1)
- optical sensor setup (1)
- optical trapping (1)
- optimization system (1)
- overload (1)
- physiology (1)
- plug flow reactor (1)
- polyetheretherketone (PEEK) (1)
- portfolio risk (1)
- power-to-gas (1)
- prebiotic (1)
- production planning and control (1)
- professional skills (1)
- proton therapy (1)
- protons (1)
- purchase factor (1)
- qNMR (1)
- random effects (1)
- rapid tooling (1)
- recombinant expression (1)
- recyclebar (1)
- relative dosimetry (1)
- reparierbar (1)
- retinal microvasculature (1)
- schlafen (1)
- service-oriented architectures (1)
- shopping behavior (1)
- smart-charging (1)
- sterilization (1)
- stretch-shortening cycle (1)
- structural equation model (1)
- technology planning (1)
- tobacco mosaic virus (TMV) (1)
- turnip vein clearing virus (TVCV) (1)
- volume flexibility (1)
- wastewater (1)
- water economy (1)
- yield (1)
- α-aminoacylase (1)
- ε-lysine acylase (1)
Zugriffsart
- weltweit (97)
- campus (47)
- bezahl (31)
- fachbereichsweit (FB4) (12)
Extracting workflow nets from textual descriptions can be used to simplify guidelines or formalize textual descriptions of formal processes like business processes and algorithms. The task of manually extracting processes, however, requires domain expertise and effort. While automatic process model extraction is desirable, annotating texts with formalized process models is expensive. Therefore, there are only a few machine-learning-based extraction approaches. Rule-based approaches, in turn, require domain specificity to work well and can rarely distinguish relevant and irrelevant information in textual descriptions. In this paper, we present GUIDO, a hybrid approach to the process model extraction task that first, classifies sentences regarding their relevance to the process model, using a BERT-based sentence classifier, and second, extracts a process model from the sentences classified as relevant, using dependency parsing. The presented approach achieves significantly better resul ts than a pure rule-based approach. GUIDO achieves an average behavioral similarity score of 0.93. Still, in comparison to purely machine-learning-based approaches, the annotation costs stay low.
In recent years, the development of large pretrained language models, such as BERT and GPT, significantly improved information extraction systems on various tasks, including relation classification. State-of-the-art systems are highly accurate on scientific benchmarks. A lack of explainability is currently a complicating factor in many real-world applications. Comprehensible systems are necessary to prevent biased, counterintuitive, or harmful decisions.
We introduce semantic extents, a concept to analyze decision patterns for the relation classification task. Semantic extents are the most influential parts of texts concerning classification decisions. Our definition allows similar procedures to determine semantic extents for humans and models. We provide an annotation tool and a software framework to determine semantic extents for humans and models conveniently and reproducibly. Comparing both reveals that models tend to learn shortcut patterns from data. These patterns are hard to detect with current interpretability methods, such as input reductions. Our approach can help detect and eliminate spurious decision patterns during model development. Semantic extents can increase the reliability and security of natural language processing systems. Semantic extents are an essential step in enabling applications in critical areas like healthcare or finance. Moreover, our work opens new research directions for developing methods to explain deep learning models.
Preprint: Studies on the enzymatic reduction of levulinic acid using Chiralidon-R and Chiralidon-S
(2023)
The enzymatic reduction of levulinic acid by the chiral catalysts Chiralidon-R and Chiralidon-S which are commercially available superabsorbed alcohol dehydrogenases is described. The Chiralidon®-R/S reduces the levulinic acid to the (R,S)-4-hydroxy valeric acid and the (R)- or (S)- gamma-valerolactone.
Durch das WEMoG (Gesetz v. 16.10.2020, BGBl. I 2187) hat der Gesetzgeber die Regelung des § 20 WEG eingeführt. Demnach ist auch für bauliche Veränderungen an Räumen und Flächen, die einem Sondernutzungsrecht unterliegen, die Zustimmung der Gemeinschaft notwendig. Der BGH hat nun mit Urt. v. 17.3.2023 –V ZR 140/22, MDR 2023, 619 deutlich gemacht, dass bei Fehlen eines entsprechenden Beschlusses, die bauliche Veränderung durch einen einzelnen Wohnungseigentümer nicht vorgenommen werden darf, sondern eine rechtswidrige Eigentumsbeeinträchtigung darstellt. Der folgende Beitrag nimmt die Entscheidung zum Anlass, um die neue Rechtslage durch § 20 WEG eingehend zu erläutern. Gleichzeitig werden die Folgen der aktuellen Entscheidung näher dargestellt.
By developing innovative solutions to social and environmental problems, sustainable ventures carry greatpotential. Entrepreneurship which focuses especially on new venture creation can be developed through education anduniversities, in particular, are called upon to provide an impetus for social change. But social innovations are associatedwith certain hurdles, which are related to the multi-dimensionality, i.e. the tension between creating social,environmental and economic value and dealing with a multiplicity of stakeholders. The already complex field ofentrepreneurship education has to face these challenges. This paper, therefore, aims to identify starting points for theintegration of sustainability into entrepreneurship education. To pursue this goal experiences from three differentproject initiatives between the partner universities: Lapland University of Applied Sciences, FH Aachen University ofApplied Sciences and Turiba University are reflected and findings are systematically condensed into recommendationsfor education on sustainable entrepreneurship.
Market abstraction of energy markets and policies - application in an agent-based modeling toolbox
(2023)
In light of emerging challenges in energy systems, markets are prone to changing dynamics and market design. Simulation models are commonly used to understand the changing dynamics of future electricity markets. However, existing market models were often created with specific use cases in mind, which limits their flexibility and usability. This can impose challenges for using a single model to compare different market designs. This paper introduces a new method of defining market designs for energy market simulations. The proposed concept makes it easy to incorporate different market designs into electricity market models by using relevant parameters derived from analyzing existing simulation tools, morphological categorization and ontologies. These parameters are then used to derive a market abstraction and integrate it into an agent-based simulation framework, allowing for a unified analysis of diverse market designs. Furthermore, we showcase the usability of integrating new types of long-term contracts and over-the-counter trading. To validate this approach, two case studies are demonstrated: a pay-as-clear market and a pay-as-bid long-term market. These examples demonstrate the capabilities of the proposed framework.
Background
Hip fractures are a common and costly health problem, resulting in significant morbidity and mortality, as well as high costs for healthcare systems, especially for the elderly. Implementing surgical preventive strategies has the potential to improve the quality of life and reduce the burden on healthcare resources, particularly in the long term. However, there are currently limited guidelines for standardizing hip fracture prophylaxis practices.
Methods
This study used a cost-effectiveness analysis with a finite-state Markov model and cohort simulation to evaluate the primary and secondary surgical prevention of hip fractures in the elderly. Patients aged 60 to 90 years were simulated in two different models (A and B) to assess prevention at different levels. Model A assumed prophylaxis was performed during the fracture operation on the contralateral side, while Model B included individuals with high fracture risk factors. Costs were obtained from the Centers for Medicare & Medicaid Services, and transition probabilities and health state utilities were derived from available literature. The baseline assumption was a 10% reduction in fracture risk after prophylaxis. A sensitivity analysis was also conducted to assess the reliability and variability of the results.
Results
With a 10% fracture risk reduction, model A costs between $8,850 and $46,940 per quality-adjusted life-year ($/QALY). Additionally, it proved most cost-effective in the age range between 61 and 81 years. The sensitivity analysis established that a reduction of ≥ 2.8% is needed for prophylaxis to be definitely cost-effective. The cost-effectiveness at the secondary prevention level was most sensitive to the cost of the contralateral side’s prophylaxis, the patient’s age, and fracture treatment cost. For high-risk patients with no fracture history, the cost-effectiveness of a preventive strategy depends on their risk profile. In the baseline analysis, the incremental cost-effectiveness ratio at the primary prevention level varied between $11,000/QALY and $74,000/QALY, which is below the defined willingness to pay threshold.
Conclusion
Due to the high cost of hip fracture treatment and its increased morbidity, surgical prophylaxis strategies have demonstrated that they can significantly relieve the healthcare system. Various key assumptions facilitated the modeling, allowing for adequate room for uncertainty. Further research is needed to evaluate health-state-associated risks.
Background
Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians.
Methods
In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204).
Measurements and main results
PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42% ± 1.77% vs. 4.64% ± 2.59%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5–190.2] vs. 189.1 [179.4–197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8–0.9] vs. 0.88 [0.8–0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = − 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters.
Conclusion
Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management.
The steel prefabricated family house ›Quelle-Fertighaus‹ designed and constructed by the German company Quelle, is an innovative modular system commercialised in 1962. All aspects of the Quelle-Fertighaus are planned on the principle of minimal effort for maximal flexibility. The clever design of the ground plan based on a 4 m × 7 m module offers the flexibility for either one to three additional modules.
The steel construction is innovative and unique, consisting of load-bearing portal frames acting as braces. The house design is furthermore characterised by a simple metrical grid layout and the practical placement of the foundation and basement, which allowed the very cost-effective production and the lowest price for a prefabricated family house in Germany during the postwar era. Nowadays its portal-frame-construction offers an interesting approach for its renovation and transformation according to present building demands.
The eVTOL industry is a rapidly growing mass market expected to start in 2024. eVTOL compete, caused by their predicted missions, with ground-based transportation modes, including mainly passenger cars. Therefore, the automotive and classical aircraft design process is reviewed and compared to highlight advantages for eVTOL development. A special focus is on ergonomic comfort and safety. The need for further investigation of eVTOL’s crashworthiness is outlined by, first, specifying the relevance of passive safety via accident statistics and customer perception analysis; second, comparing the current state of regulation and certification; and third, discussing the advantages of integral safety and applying the automotive safety approach for eVTOL development. Integral safety links active and passive safety, while the automotive safety approach means implementing standardized mandatory full-vehicle crash tests for future eVTOL. Subsequently, possible crash impact conditions are analyzed, and three full-vehicle crash load cases are presented.
Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan. These highly flexible dynamic systems can exhibit uncommon aeroelastic instabilities, which should be carefully investigated to ensure safe operation. The interaction between the propeller and the wing is of particular importance. It is known that whirl flutter is stabilized by wing motion and wing aerodynamics. This paper investigates the effect of a propeller onto wing flutter as a function of span position and mounting stiffness between the propeller and wing. The analysis of a comparison between a tractor and pusher configuration has shown that the coupled system is more stable than the standalone wing for propeller positions near the wing tip for both configurations. The wing fluttermechanism is mostly affected by the mass of the propeller and the resulting change in eigenfrequencies of the wing. For very weak mounting stiffnesses, whirl flutter occurs, which was shown to be stabilized compared to a standalone propeller due to wing motion. On the other hand, the pusher configuration is, as to be expected, the more critical configuration due to the attached mass behind the elastic axis.
This work proposes a hybrid algorithm combining an Artificial Neural Network (ANN) with a conventional local path planner to navigate UAVs efficiently in various unknown urban environments. The proposed method of a Hybrid Artificial Neural Network Avoidance System is called HANNAS. The ANN analyses a video stream and classifies the current environment. This information about the current Environment is used to set several control parameters of a conventional local path planner, the 3DVFH*. The local path planner then plans the path toward a specific goal point based on distance data from a depth camera. We trained and tested a state-of-the-art image segmentation algorithm, PP-LiteSeg. The proposed HANNAS method reaches a failure probability of 17%, which is less than half the failure probability of the baseline and around half the failure probability of an improved, bio-inspired version of the 3DVFH*. The proposed HANNAS method does not show any disadvantages regarding flight time or flight distance.
Assistance systems have been widely adopted in the manufacturing sector to facilitate various processes and tasks in production environments. However, existing systems are mostly equipped with rigid functional logic and do not provide individual user experiences or adapt to their capabilities. This work integrates human factors in assistance systems by adjusting the hardware and instruction presented to the workers’ cognitive and physical demands. A modular system architecture is designed accordingly, which allows a flexible component exchange according to the user and the work task. Gamification, the use of game elements in non-gaming contexts, has been further adopted in this work to provide level-based instructions and personalised feedback. The developed framework is validated by applying it to a manual workstation for industrial assembly routines.
Rocket engine test facilities and launch pads are typically equipped with a guide tube. Its purpose is to ensure the controlled and safe routing of the hot exhaust gases. In addition, the guide tube induces a suction that effects the nozzle flow, namely the flow separation during transient start-up and shut-down of the engine. A cold flow subscale nozzle in combination with a set of guide tubes was studied experimentally
to determine the main influencing parameters.
This paper introduces an inexpensive Wiegand-sensor-based rotary encoder that avoids rotating magnets and is suitable for electrical-drive applications. So far, Wiegand-sensor-based encoders usually include a magnetic pole wheel with rotating permanent magnets. These encoders combine the disadvantages of an increased magnet demand and a limited maximal speed due to the centripetal force acting on the rotating magnets. The proposed approach reduces the total demand of permanent magnets drastically. Moreover, the rotating part is manufacturable from a single piece of steel, which makes it very robust and cheap. This work presents the theoretical operating principle of the proposed approach and validates its benefits on a hardware prototype. The presented proof-of-concept prototype achieves a mechanical resolution of 4.5 ° by using only 4 permanent magnets, 2Wiegand sensors and a rotating steel gear wheel with 20 teeth.