Refine
Year of publication
- 2019 (387) (remove)
Institute
- FH Aachen (74)
- Fachbereich Medizintechnik und Technomathematik (71)
- IfB - Institut für Bioengineering (45)
- Fachbereich Elektrotechnik und Informationstechnik (44)
- Fachbereich Luft- und Raumfahrttechnik (44)
- Fachbereich Wirtschaftswissenschaften (35)
- Fachbereich Bauingenieurwesen (28)
- Fachbereich Energietechnik (27)
- Fachbereich Maschinenbau und Mechatronik (27)
- INB - Institut für Nano- und Biotechnologien (20)
Document Type
- Article (123)
- Conference Proceeding (94)
- Administrative publication (72)
- Part of a Book (43)
- Book (25)
- Other (9)
- Doctoral Thesis (5)
- Patent (5)
- Review (4)
- Conference: Meeting Abstract (2)
Keywords
- Amtliche Mitteilung (68)
- Bachelor (31)
- Master (29)
- Prüfungsordnung (29)
- Lesbare Fassung (28)
- Studien- und Prüfungsordnung (21)
- Änderungsordnung (20)
- Bauingenieurwesen (17)
- Elektrotechnik (8)
- Holzingenieurwesen (6)
- Richtlinie (6)
- Industrial Engineering (5)
- Zugangsordnung (5)
- Facility Management (4)
- Information Systems Engineering (4)
- Amtliche Mitteilungen (3)
- Aufhebungsordnung (3)
- Digitalisierung (3)
- Gesamtprüfungsordnung (3)
- Beitragsordnung der Studierendenschaft (2)
- Betriebswirtschaft Praxis Plus (2)
- Datenschutz (2)
- Durchführung von Sonderveranstaltungen (2)
- Einstellungsordnung (2)
- Energiewirtschaft (2)
- Enterprise Architecture (2)
- Informatik (2)
- Lehrveranstaltungsprämien (2)
- Maschinenbau und Mechatronik (2)
- Nuclear Applications (2)
- Physiotherapie (2)
- Rektorat (2)
- Robotic Process Automation (2)
- Seismic design (2)
- Veranstaltungsrichtlinie (2)
- Wirtschaftsingenieurwesen (2)
- lesbare Fassung (2)
- studentische Hilfskräfte (2)
- wissenschaftliche Hilfkräfte (2)
- 2019 (1)
- 2020 (1)
- 2021 (1)
- Achilles tendon (1)
- Advanced driver assistance systems (ADAS/AD) (1)
- Aircraft design (1)
- Aktualisierung (1)
- Analytics (1)
- Arbeit 4.0 (1)
- Architectural gear ratio (1)
- Architektur (1)
- Architekturforschung (1)
- Architekturwissenschaft (1)
- Assistive technology (1)
- Automatic control (1)
- BEV (1)
- Bauingenieurwesen mit Orientierungssemester (1)
- Bauingieurwesen (1)
- Beitragsordnung (1)
- Bundesdatenschutzgesetz (2017) (1)
- Case Study (1)
- Change Management (1)
- Chatbots (1)
- Chemie und Biotechnologie (1)
- Combustion (1)
- Components (1)
- Corporate Culture (1)
- Correlations (1)
- Datenschutz-Management (1)
- Datenschutzgrundverordnung (1)
- Datenschutzrecht (1)
- Decentral (1)
- Design examples (1)
- Design rules (1)
- Deutschland (1)
- Didaktik (1)
- Digital Age (1)
- Diversity Management (1)
- Drag (1)
- EU-DSGVO (1)
- EU-Datenschutz-Grundverordnung (1)
- EU-Datenschutzgrundverordnung (1)
- Earthquake (1)
- Elektronik (1)
- Elektrotechnik (Teilzeit) (1)
- Emilia-Romagna earthquake (1)
- Empirical consequence curves (1)
- Empirical fragility functions (1)
- Energietechnik (1)
- Engineering (1)
- Engineering optimization (1)
- Epistemische Neugier (1)
- Eurocode 8 (1)
- Force (1)
- Forschung (1)
- Forschungsinformationssystem (1)
- Forschungsorientierte Lehre (1)
- Forschungsprozess (1)
- Fremdfirmenrichtlinie (1)
- Gearbox (1)
- Geometry (1)
- Geschäftsmodell (1)
- Gleichstellungsquoten (1)
- Goodness-of-fit test (1)
- Graph Theory (1)
- Green aircraft (1)
- Gust wind response (1)
- Hochschule (1)
- Human-Computer interaction (1)
- Hybrid-electric aircraft (1)
- Hydrogen (1)
- ISO 26262 (1)
- In-plane (1)
- Industrial units (1)
- Information Systems Engineering (Teilzeit) (1)
- Informationsgesellschaft (1)
- Innovation Management (1)
- Internationales Recht / Europarecht (1)
- Internetökonomie (1)
- Isolation (1)
- Iterative learning control (1)
- Knee (1)
- Load modeling (1)
- Low NOx (1)
- Low emission (1)
- Machine learning (1)
- Master Architektur (1)
- Mechanical (1)
- Mixed-Methods (1)
- Mixed-integer nonlinear black-box optimization (1)
- Multi-sample problem (1)
- On-site (1)
- Open Data (1)
- Optimization (1)
- Out-of-plane (1)
- PBEE (1)
- Parametric bootstrap (1)
- Powertrain (1)
- Pre-treatment (1)
- Precast buildings (1)
- Preface (1)
- Product family optimization (1)
- Prozessautomatisierung (1)
- Pushover analysis (1)
- RWTH Aachen (1)
- Rehabilitation engineering (1)
- Resilience Assessment (1)
- Response spectrum (1)
- Running (1)
- Safety of the intended functionality (SOTIF) (1)
- Safety-critical systems validation (1)
- Seismic (1)
- Selbstwirksamkeit (1)
- Serviceintegration (1)
- Silos (1)
- Social Media (1)
- Software Robots (1)
- Spectral analysis (1)
- Statistics (1)
- Stiffness (1)
- Studienbeginn 2018/19 (1)
- Studieneingangsphase (1)
- Studiengangs- und Prüfungsordnung (1)
- Studierendenwerk (1)
- Studierfähigkeit (1)
- Tanks (1)
- Tendon properties (1)
- Training (1)
- Unmanned Air Vehicle (1)
- Volume of confidence regions (1)
- WLTP (1)
- Water Supply System (1)
- Wind turbulence (1)
- Wirkungsforschung (1)
- asymptotic relative efficiency (1)
- batch reproducibility (1)
- concentrating collector (1)
- environmental correlation (1)
- fluorescent protein carrier (1)
- frequency mixing magnetic detection (1)
- greenhouse cultivation (1)
- intrinsische Motivation (1)
- likelihood ratio test (1)
- magnetic actuation (1)
- magnetic sandwich immunoassay (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- plant molecular farming (1)
- point-focussing system (1)
- raytracing (1)
- responsive space (1)
- small solar system body characterisation (1)
- small spacecraft asteroid lander (1)
- small spacecraft solar sail (1)
- solar process heat (1)
- superparamagnetic bead (1)
- system engineering (1)
- Änderung (1)
Aufgrund des § 2 Absatz 4 Satz 1 in Verbindung mit § 64 des Gesetzes über die Hochschulen des Landes Nordrhein-Westfalen (Hochschulgesetz – HG) vom 16. September 2014 (GV. NRW. S. 547), zuletzt geändert durch Artikel 3 des Gesetzes
vom 17. Oktober 2017 (GV. NRW. S. 806), und der Rahmenprüfungsordnung (RPO) für die Bachelor- und Masterstudiengänge an der Fachhochschule Aachen vom 1. Februar 2018 (FH-Mitteilung Nr. 3/2018) hat der Fachbereich Architektur folgende
Änderung der Prüfungsordnung vom 5. Juli 2018 (FH-Mitteilung Nr. 105/2018) erlassen.
Aufgrund des § 2 Absatz 4 Satz 1 in Verbindung mit § 64 des Gesetzes über die Hochschulen des Landes Nordrhein-Westfalen (Hochschulgesetz – HG) vom 16. September 2014 (GV. NRW. S. 547), zuletzt geändert durch Artikel 3 des Gesetzes vom 17. Oktober 2017 (GV. NRW. S. 806), und der Rahmenprüfungsordnung (RPO) für die Bachelor- und Masterstudiengänge an der Fachhochschule Aachen vom 1. Februar 2018 (FH-Mitteilung Nr. 3/2018) hat der Fachbereich Architektur folgende Änderung der Prüfungsordnung vom 5. Juli 2018 (FH-Mitteilung Nr. 104/2018) erlassen.
The movement of magnetic beads due to a magnetic field gradient is of great interest in different application fields. In this report we present a technique based on a magnetic tweezers setup to measure the velocity factor of magnetically actuated individual superparamagnetic beads in a fluidic environment. Several beads can be tracked simultaneously in order to gain and improve statistics. Furthermore we show our results for different beads with hydrodynamic diameters between 200 and 1000 nm from diverse manufacturers. These measurement data can, for example, be used to determine design parameters for a magnetic separation system, like maximum flow rate and minimum separation time, or to select suitable beads for fixed experimental requirements.
For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.
In modern bioanalytical methods, it is often desired to detect several targets in one sample within one measurement. Immunological methods including those that use superparamagnetic beads are an important group of techniques for these applications. The goal of this work is to investigate the feasibility of simultaneously detecting different superparamagnetic beads acting as markers using the magnetic frequency mixing technique. The frequency of the magnetic excitation field is scanned while the lower driving frequency is kept constant. Due to the particles’ nonlinear magnetization, mixing frequencies are generated. To record their amplitude and phase information, a direct digitization of the pickup-coil’s signal with subsequent Fast Fourier Transformation is performed. By synchronizing both magnetic beads using frequency scanning in magnetic frequency mixing technique magnetic fields, a stable phase information is gained. In this research, it is shown that the amplitude of the dominant mixing component is proportional to the amount of superparamagnetic beads inside a sample. Additionally, it is shown that the phase does not show this behaviour. Excitation frequency scans of different bead types were performed, showing different phases, without correlation to their diverse amplitudes. Two commercially available beads were selected and a determination of their amount in a mixture is performed as a demonstration for multiplex measurements.
Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection
(2019)
Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin’s B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more
than 700 ng/ml.
Masonry infill walls are commonly used in reinforced concrete (RC) frame structures, also in seismically active areas, although they often experience serious damage during earthquakes. One of the main reasons for their poor behaviour is the connection to the frame, which is usually constructed using mortar. This paper describes the novel solution for infill/frame connection based on application of elastomeric material between them. The system called INODIS (Innovative Decoupled Infill System) has the aim to postpone the activation of infill in in-plane direction and at the same time to provide sufficient out-of-plane support. First, experimental tests on infilled frame specimens are presented and the comparison of the results between traditionally infilled frames and infilled frames with the INODIS system are given. The results are then used for calibration and validation of numerical model, which can be further employed for investigating the influence of some material parameters on the behaviour of infilled frames with the INODIS system.
The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.
Suppose we have k samples X₁,₁,…,X₁,ₙ₁,…,Xₖ,₁,…,Xₖ,ₙₖ with different sample sizes ₙ₁,…,ₙₖ and unknown underlying distribution functions F₁,…,Fₖ as observations plus k families of distribution functions {G₁(⋅,ϑ);ϑ∈Θ},…,{Gₖ(⋅,ϑ);ϑ∈Θ}, each indexed by elements ϑ from the same parameter set Θ, we consider the new goodness-of-fit problem whether or not (F₁,…,Fₖ) belongs to the parametric family {(G₁(⋅,ϑ),…,Gₖ(⋅,ϑ));ϑ∈Θ}. New test statistics are presented and a parametric bootstrap procedure for the approximation of the unknown null distributions is discussed. Under regularity assumptions, it is proved that the approximation works asymptotically, and the limiting distributions of the test statistics in the null hypothesis case are determined. Simulation studies investigate the quality of the new approach for small and moderate sample sizes. Applications to real-data sets illustrate how the idea can be used for verifying model assumptions.