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Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection
(2010)
Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs
(2010)
Organisation
(2010)
Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.
Forschungsbericht 2010
(2010)
Forschungsbericht / Themenheft : Energie, Mobilität, Luft- und Raumfahrt. 72 S. : Ill., graph. Darst. gedruckte Ausgabe unter der Signatur 91 AKN 100-2010 Inhaltsverzeichnis: 4 Grußworte Prorektorin Prof. Dr. rer. nat. Christiane Vaeßen 6 Highlightprojekte 10 Solar-Institut-Jülich 11 Aquasol und CuveWaters 13 PaRiKo 14 Science College Overbach 15 Summer School Renewable Energy 16 Solarturm Jülich 18 Hochtemperatur-Wanderbett-Wärmeübertrager 20 Stromversorgung mit einem hohen Anteil erneuerbarer Energieerzeuger 21 Standards für solare Prozesswäre 22 Solarturmtechnik (viCERP) 24 Novum-Institut 25 MAK-Energie 26 Exbrut 27 Biogasversuchsanlage 28 MiProBa 30 Elektrotechnik 30 Ultrakompakte Leuchtstofflampe 32 ITP Mobilität 34 Elektromobilität 34 E_bike 37 Konzept-Elektrofahrzeug 4e4 40 Elektromobilitätskonzepte 43 Mobilität und Verkehr 43 Mobiliätskonzept für FH Aachen 44 Luft- und Raumfahrt, Automotive 44 Sonnensegel 46 COMPASS 48 Antriebe für Werkzeugmaschinen und Fahrzeuge 50 SAAE 52 Wasserstoff-Gasturbine 53 HyDI 54 Bioethanol als Flugbenzin 56 Zertifizierung von Luftfahrtantrieben 58 Hydrostatischer Probellerantrieb 59 Hybridantrieb und Flugzeug 61 Mix-SCR 62 Abgasnachbehandlung 3D-Keramik 63 VisMut 64 WING 68 Silent Structure 70 Entwicklungspotenzial bei variablen Kfz-Ölpumpen 72 Kunststoff-Rotationsmesser