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Einschränkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur
(2013)
Die fibulare Bandruptur zählt zu einer der am häufigsten auftretenden Verletzungen des
Bewegungsapparats. In den meisten Fällen wird heute die konservativ frühfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschränkung von Taluskippung und Talusvorschub
untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" Röntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint.
The semiconductor field-effect platform represents a powerful tool for detecting the adsorption and binding of charged macromolecules with direct electrical readout. In this work, a capacitive electrolyte–insulator–semiconductor (EIS) field-effect sensor consisting of an Al-p-Si-SiO2 structure has been applied for real-time in situ electrical monitoring of the layer-by-layer formation of polyelectrolyte (PE) multilayers (PEM). The PEMs were deposited directly onto the SiO2 surface without any precursor layer or drying procedures. Anionic poly(sodium 4-styrene sulfonate) and cationic weak polyelectrolyte poly(allylamine hydrochloride) have been chosen as a model system. The effect of the ionic strength of the solution, polyelectrolyte concentration, number and polarity of the PE layers on the characteristics of the PEM-modified EIS sensors have been studied by means of capacitance–voltage and constant-capacitance methods. In addition, the thickness, surface morphology, roughness and wettabilityof the PE mono- and multilayers have been characterised by ellipsometry, atomic force microscopy and water contact-angle methods, respectively. To explain potential oscillations on the gate surface and signal behaviour of the capacitive field-effect EIS sensor modified with a PEM, a simplified electrostatic model that takes into account the reduced electrostatic screening of PE charges by mobile ions within the PEM has been proposed and discussed.
ETHICS is concerned with evaluating, measuring and making improvements in the thermal and energy performance of steel-clad and steel-framed buildings. It addresses basic building physics performance at a laboratory and full-scale level, and the preparation of design guidance for commercial, industrial and residential buildings. It includes the development of design tools to assist users in assessing whole-building performance, and calibrates these tools against whole-building measurements, which will be obtained from this research. Opportunities for renewable energy and other energy-saving features will be assessed. This project focuses on objectives that are of particular interest for the design of new steel constructions regarding energy efficiency. ETHICS investigates the as-built performance by on-site tests regarding air tightness and heat transfer properties of the building envelope and by monitoring the energy consumption and thermal comfort of selected up-to-date steel buildings. As energy efficiency is a key requirement for design and construction of buildings in the future, this project provides well-founded scientific data, which prove the high energy performance of current steel constructions and work out details for further improvements to maintain and extend the position of steel products in the construction sector.
Die Telekommunikationsindustrie hat in den letzten Jahrzehnten einen enormen Wandel vollzogen. Für Telekommunikationsunternehmen erfordert dies fundamentale Umstrukturierungen von Strategie, Prozessen, Anwendungssystemen und Netzwerktechnologien. Dabei spielen Unternehmensarchitekturen und Referenzmodelle eine wichtige Rolle. Zwar existieren in der Praxis anerkannte Referenzmodelle, aber wie sind diese für eine systematische Transformation zu gestalten? Wie sieht eine konkrete Lösung für die Telekommunikationsindustrie aus?
Als Antwort stellt Christian Czarnecki in seinem Buch eine referenzmodellbasierte Unternehmensarchitektur vor. Basierend auf einer umfangreichen Untersuchung von Transformationsprojekten werden Probleme und Anforderungen der Praxis identifiziert, für die mit Methoden der Unternehmenstransformation, Referenzmodellierung und Unternehmensarchitektur ein Lösungsvorschlag entwickelt und evaluiert wird. Dieser besteht u. a. aus detaillierten Anwendungsfällen, Referenzprozessabläufen, einer Zuordnung von Prozessen zu Anwendungssystemen sowie Handlungsempfehlungen zur Virtualisierung.
Für Wissenschaftler und Studierende der Wirtschaftsinformatik zeigt das Buch neue Erkenntnisse einer anwendungsorientierten Referenzmodellierung. Für Praktiker liefert es eine methodisch fundierte Lösung für die aktuellen Transformationsbedarfe der Telekommunikationsindustrie. Christian Czarnecki arbeitet seit 2004 als Unternehmensberater und hat viele Telekommunikationsunternehmen bei deren Transformation begleitet. In 2013 erfolgte die Promotion zum Doktoringenieur an der Otto-von-Guericke-Universität Magdeburg.
Die Fahrzeugkarosserie bildet als größte funktionale und organisatorische Systemeinheit ein zentrales Kompetenzfeld der OEMs. Für den Fahrzeughersteller stellt der Karosserierohbau eine hohe Kernkompetenz sowohl in der Produktentwicklung als auch in der Produktion dar. Neue, innovative Karosseriebauweisen, bspw. aufgrund eines neuen Fahrzeugkonzeptes oder neuer Anforderungen, bedeuten für den OEM auch gleichzeitig die intensive Auseinandersetzung mit Kompetenzfokussierung bzw. Wertschöpfungsverlagerungen.
Erfolgreiches IT-Marketing
(2013)
Euler-based induced drag estimation for highly non-planar lifting systems during conceptional design
(2013)
Experimental investigation of selective laser melting of lunar regolith for in-situ applications
(2013)
Light-addressable potentiometric sensors (LAPS) are semiconductor-based potentiometric sensors, with the advantage to detect the concentration of a chemical species in a liquid solution above the sensor surface in a spatially resolved manner. The addressing is achieved by a modulated and focused light source illuminating the semiconductor and generating a concentration-depending photocurrent. This work introduces a LAPS set-up that is able to monitor the electrical impedance in addition to the photocurrent. The impedance spectra of a LAPS structure, with and without illumination, as well as the frequency behaviour of the LAPS measurement are investigated. The measurements are supported by electrical equivalent circuits to explain the impedance and the LAPS-frequency behaviour. The work investigates the influence of different parameters on the frequency behaviour of the LAPS. Furthermore, the phase shift of the photocurrent, the influence of the surface potential as well as the changes of the sensor impedance will be discussed.
The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered.
The network approach towards the analysis of the dynamics of complex systems has been successfully applied in a multitude of studies in the neurosciences and has yielded fascinating insights. With this approach, a complex system is considered to be composed of different constituents which interact with each other. Interaction structures can be compactly represented in interaction networks. In this contribution, we present a brief overview about how interaction networks are derived from multivariate time series, about basic network characteristics, and about challenges associated with this analysis approach.
Biotechnological downstream processing is usually an elaborate procedure, requiring a multitude of unit operations to isolate the target component. Besides the disadvantageous space-time yield, the risks of cross-contaminations and product loss grow fast with the complexity of the isolation procedure. A significant reduction of unit operations can be achieved by application of magnetic particles, especially if these are functionalized with affinity ligands. As magnetic susceptible materials are highly uncommon in biotechnological processes, target binding and selective separation of such particles from fermentation or reactions broths can be done in a single step. Since the magnetizable particles can be produced from iron salts and low priced polymers, a single-use implementation of these systems is highly conceivable. In this article, the principles of magnetizable particles, their synthesis and functionalization are explained. Furthermore, applications in the area of reaction engineering, microfluidics and downstream processing are discussed focusing on established single-use technologies and development potential.