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Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the “Deutsche Bluthochdruck Liga” this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model.
In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology.
Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.
Air-sand heat exchanger
(2011)
This paper describes the concept of an innovative, interdisciplinary, user-oriented earthquake warning and rapid response system coupled with a structural health monitoring system (SHM), capable to detect structural damages in real time. The novel system is based on interconnected decentralized seismic and structural health monitoring sensors. It is developed and will be exemplarily applied on critical infrastructures in Lower Rhine Region, in particular on a road bridge and within a chemical industrial facility. A communication network is responsible to exchange information between sensors and forward warnings and status reports about infrastructures’health condition to the concerned recipients (e.g., facility operators, local authorities). Safety measures such as emergency shutdowns are activated to mitigate structural damages and damage propagation. Local monitoring systems of the infrastructures are integrated in BIM models. The visualization of sensor data and the graphic representation of the detected damages provide spatial content to sensors data and serve as a useful and effective tool for the decision-making processes after an earthquake in the region under consideration.
Combined with the use of renewable energy sources for
its production, Hydrogen represents a possible alternative gas
turbine fuel for future low emission power generation. Due to
its different physical properties compared to other fuels such
as natural gas, well established gas turbine combustion
systems cannot be directly applied for Dry Low NOx (DLN)
Hydrogen combustion. This makes the development of new
combustion technologies an essential and challenging task
for the future of hydrogen fueled gas turbines.
The newly developed and successfully tested “DLN
Micromix” combustion technology offers a great potential to
burn hydrogen in gas turbines at very low NOx emissions.
Aiming to further develop an existing burner design in terms
of increased energy density, a redesign is required in order to
stabilise the flames at higher mass flows and to maintain low
emission levels.
For this purpose, a systematic design exploration has
been carried out with the support of CFD and optimisation
tools to identify the interactions of geometrical and design
parameters on the combustor performance. Aerodynamic
effects as well as flame and emission formation are observed
and understood time- and cost-efficiently. Correlations
between single geometric values, the pressure drop of the
burner and NOx production have been identified as a result.
This numeric methodology helps to reduce the effort of
manufacturing and testing to few designs for single
validation campaigns, in order to confirm the flame stability
and NOx emissions in a wider operating condition field.
The initial idea of Robotic Process Automation (RPA) is the automation of business processes through the presentation layer of existing application systems. For this simple emulation of user input and output by software robots, no changes of the systems and architecture is required. However, considering strategic aspects of aligning business and technology on an enterprise level as well as the growing capabilities of RPA driven by artificial intelligence, interrelations between RPA and Enterprise Architecture (EA) become visible and pose new questions. In this paper we discuss the relationship between RPA and EA in terms of perspectives and implications. As workin- progress we focus on identifying new questions and research opportunities related to RPA and EA.
This paper presents an approach for reducing the cognitive load for humans working in quality control (QC) for production processes that adhere to the 6σ -methodology. While 100% QC requires every part to be inspected, this task can be reduced when a human-in-the-loop QC process gets supported by an anomaly detection system that only presents those parts for manual inspection that have a significant likelihood of being defective. This approach shows good results when applied to image-based QC for metal textile products.
The Effect of Openings on Out-of-Plane Capacity of Masonry Infilled Reinforced Concrete Frames
(2018)
Digital twins enable the modeling and simulation of real-world entities (objects, processes or systems), resulting in improvements in the associated value chains. The emerging field of quantum computing holds tremendous promise forevolving this virtualization towards Quantum (Digital) Twins (QDT) and ultimately Quantum Twins (QT). The quantum (digital) twin concept is not a contradiction in terms - but instead describes a hybrid approach that can be implemented using the technologies available today by combining classicalcomputing and digital twin concepts with quantum processing. This paperpresents the status quo of research and practice on quantum (digital) twins. It alsodiscuses their potential to create competitive advantage through real-timesimulation of highly complex, interconnected entities that helps companies better
address changes in their environment and differentiate their products andservices.
Energy-efficient components do not automatically lead to energy-efficient systems. Technical Operations Research (TOR) shifts the focus from the single component to the system as a whole and finds its optimal topology and operating strategy simultaneously. In previous works, we provided a preselected construction kit of suitable components for the algorithm. This approach may give rise to a combinatorial explosion if the preselection cannot be cut down to a reasonable number by human intuition. To reduce the number of discrete decisions, we integrate laws derived from similarity theory into the optimization model. Since the physical characteristics of a production series are similar, it can be described by affinity and scaling laws. Making use of these laws, our construction kit can be modeled more efficiently: Instead of a preselection of components, it now encompasses whole model ranges. This allows us to significantly increase the number of possible set-ups in our model. In this paper, we present how to embed this new formulation into a mixed-integer program and assess the run time via benchmarks. We present our approach on the example of a ventilation system design problem.
In times of planned obsolescence the demand for sustainability keeps growing. Ideally, a technical system is highly reliable, without failures and down times due to fast wear of single components. At the same time, maintenance should preferably be limited to pre-defined time intervals. Dispersion of load between multiple components can increase a system’s reliability and thus its availability inbetween maintenance points. However, this also results in higher investment costs and additional efforts due to higher complexity. Given a specific load profile and resulting wear of components, it is often unclear which system structure is the optimal one. Technical Operations Research (TOR) finds an optimal structure balancing availability and effort. We present our approach by designing a hydrostatic transmission system.
Im Hinblick auf die Klimaziele der Bundesrepublik Deutschland konzentriert sich das Projekt Diggi Twin auf die nachhaltige Gebäudeoptimierung. Grundlage für eine ganzheitliche Gebäudeüberwachung und -optimierung bildet dabei die Digitalisierung und Automation im Sinne eines Smart Buildings. Das interdisziplinäre Projekt der FH Aachen hat das Ziel, ein bestehendes Hochschulgebäude und einen Neubau an klimaneutrale Standards anzupassen. Im Rahmen des Projekts werden bekannte Verfahren, wie das Building Information Modeling (BIM), so erweitert, dass ein digitaler Gebäudezwilling entsteht. Dieser kann zur Optimierung des Gebäudebetriebs herangezogen werden, sowie als Basis für eine Erweiterung des Bewertungssystems Nachhaltiges Bauen (BNB) dienen. Mithilfe von Sensortechnologie und künstlicher Intelligenz kann so ein präzises Monitoring wichtiger Gebäudedaten erfolgen, um ungenutzte Energieeinsparpotenziale zu erkennen und zu nutzen. Das Projekt erforscht und setzt methodische Erkenntnisse zu BIM und digitalen Gebäudezwillingen praxisnah um, indem es spezifische Fragen zur Energie- und Ressourceneffizienz von Gebäuden untersucht und konkrete Lösungen für die Gebäudeoptimierung entwickelt.
Existing residential buildings have an average lifetime of 100 years. Many of these buildings will exist for at least another 50 years. To increase the efficiency of these buildings while keeping costs at reasonable rates, they can be retrofitted with sensors that deliver information to central control units for heating, ventilation and electricity. This retrofitting process should happen with minimal intervention into existing infrastructure and requires new approaches for sensor design and data transmission. At FH Aachen University of Applied Sciences, students of different disciplines work together to learn how to design, build, deploy and operate such sensors. The presented teaching project already created a low power design for a combined CO2, temperature and humidity measurement device that can be easily integrated into most home automation systems