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Wettbewerbsregeln (§§ 24-27)
(2022)
Wasserwirtschaft
(2005)
Vorwort
(2012)
Vorbemerkung vor § 1353
(2017)
Vorbemerkung vor § 1353
(2014)
Vorbemerkung vor § 1297
(2017)
Vorbemerkung vor § 1297
(2014)
Von der Königlichen Höheren Maschinenbauschule Aachen zu den Ingenieurfachbereichen der FH Aachen
(2010)
Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.
Because of its minor environmental impact, electricity generation using wind power is getting remarkable. The further growth of the wind industry depends on technological solutions to the challenges in production and construction of the turbines. Wind turbine tower vibrations, which limit power generation efficiency and cause fatigue problems with high maintenance costs, count as one of the main structural difficulties in the wind energy sector. To mitigate tower vibrations auxiliary measures are necessary. The effectiveness of tuned mass damper is verified by means of a numeric study on a 5 MW onshore reference wind turbine. Hereby, also seismic-induced vibrations and soil–structure interaction are considered. Acquired results show that tuned mass damper can effectively reduce resonant tower vibrations and improve the fatigue life of wind turbines. This chapter is also concerned with tuned liquid column damper and a semiactive application of it. Due to its geometric versatility and low prime costs, tuned liquid column dampers are a good alternative to other damping measures, in particular for slender structures like wind turbines.
Vermessung
(2016)
Vermessung
(2019)
Für die Erstellung von Maschinenbelegungsplanen wurden im Operations Research aufwendige Optimierungsverfahren konzipiert und entsprechende Programme entwickelt. Maschinenbelegungsprobleme sind klassische Vertreter der Klasse der np-vollständigen Probleme, also sichere Kandidaten für kombinatorische Explosion der Lösungsalternativen. Deshalb ist der Einsatz konventioneller Planungssysteme wegen der hohen Rechneranforderungen der gängigen Verfahren an die Hardware oft nicht praktikabel.
Der Verein Deutscher Ingenieure e.V. (VDI) ist ein gemeinnütziger, wirtschaftlich und politisch unabhängiger, technisch-wissenschaftlicher Verein von Ingenieuren und Naturwissenschaftlern. Mit über 137 000 persönlich zugeordneten Mitgliedern ist er eine der größten Ingenieur-Vereinigungen Europas und gilt in Deutschland als führender Sprecher der Technik und der Ingenieure. 1856 gegründet, hat er viele für die Technik wesentliche Entwicklungen in Gang gesetzt, so im Bereich der technischen Überwachung, der technischen Regelsetzung und Normung, der Arbeitsstudien, im gewerblichen Rechtsschutz und im Patentwesen. Seit seiner Gründung sieht es der VDI als seine Aufgabe, "das Zusammenwirken aller geistiger Kräfte der Technik im Bewusstsein ethischer Verantwortung zu fördern" und die Lebensmöglichkeiten aller Menschen durch Entwicklung und sinnvoller Anwendung technischer Mittel zu verbessern.
In competition with other modes of transport, rail freight transport is looking for solutions to become more attractive. Short-term success can be achieved through the data-driven optimization of operations and maintenance as well as the application of novel strategies such as prescriptive maintenance. After introducing the concept of prescriptive maintenance, this paper aims to prove that vehicle-focused applications of this approach indeed have the potential to increase attractiveness. However, even greater advantages can be activated if data from the horizontal network of the vehicle is available. Drawing on the state of the art in research and technology in the field of cyber-physical systems (CPS) as well as digital twins and shadows, our work serves to design a system of systems for the horizontal interconnection of a rail vehicle and to conceptualize a draft for a digital twin of a locomotive.
This chapter shows that nanomaterials obtained by high-temperature carbonization of inexpensive plant raw material such as rice husk, grape seeds, and walnut shells can serve as a basis for the production of highly efficient microbial drugs, biodestructors, biosorbents, and biocatalysts, which are promising for the remediation of the ecosystem contaminated with heavy and radioactive metals, oil and oil products. A strong interest in engineering zymology is dictated by the necessity to address the issues of monitoring enzymatic processes, treatment, and diagnosis of a number of common human diseases, environmental pollution, quality control of pharmaceuticals and food. Nanomaterials obtained by high-temperature carbonization of cheap plant raw material such as-rice husks, grape seeds and walnut shells, can serve as a basis for creating of highly effective microbial preparations-biodestructors, biosorbents and biocatalysts, which are promising for the use of contaminated ecosystems, and for restoration of human intestine microecology.
Der Themenkomplex urbane Mobilität ist getrieben durch den Verkehrsinfarkt in Ballungszentren, durch Luftverschmutzung und Lärm, sowie den Trend zum Leben in der Stadt in den städteplanerischen Fokus gerückt. Emissionsneutrale Antriebskonzepte in der Luftfahrt führen zu Ansätzen Fluggeräte einzusetzen, die batteriegetrieben vertikal aufsteigen und landen können. Flugphysikalisch und energetisch ist diese Technik nur dann sinnvoll, wenn es zwingende Gründe gibt (z.B. Rettungseinsätze), daher wird der flugphysikalische Hintergrund prinzipiell erläutert. Es werden einige aktuelle Lufttransportkonzepte für eine urbane Personenbeförderung vorgestellt. Sollte es verstärkt zu Lufttransport über Städten kommen, müssen betroffene Lufträume geordnet und überwacht werden. Wie kompatibel Lufttransportsysteme mit den heute bereits relevanten urbanen Beförderungsmitteln sein müssen, wird kritisch diskutiert. Abschließend werden die Aspekte Akzeptanz durch die Kunden und Wirtschaftlichkeit ebenso angerissen, wie die hochproblematische Rohstoffgewinnung, die Entsorgung und das Recycling von Batterien.
Lately there has been an increasing concern about uranium toxicity in some districts of Punjab State located in the North Western part of India after the publication of a report (Blaurock-Busch et al. 2010) which showed that the concentration of uranium in hair and urine of children suffering from physical deformities, neurological and mental disorder from Malwa region (Fig. 1) of Punjab State was manifold higher than the reference ranges. A train which connects the affected region with the nearby city of Bikaner which has a Cancer Hospital has been nicknamed as Cancer Express due to the frenzy generated on account of uranium related toxicity.
Neben dem durch Unfälle und Krankheiten entstehenden menschlichen Leids und der daraus resultierenden moralischen Verpflichtung, sich und seine Mitmenschen vor Schaden zu bewahren, ist der Arbeits- und Gesundheitsschutz auch ein Gebot wirtschaftlichen Handelns, da Arbeitsunfälle und Berufskrankheiten Ausfallzeiten und Kosten verursachen. So gehören Arbeits- und Gesundheitsschutz zu den wichtigen Aufgaben eines Unternehmens.
Architecture is a university subject with educational roots in both the technical university and art/specialized architecture schools, yet it lacks a strong research orientation and is focused on professional expertise. This chapter explores the particular role of research within architectural education in general by discussing two different cases for the implementation of undergraduate research in architecture: during the late 1990s and early 2000s at the University of Sheffield, UK, and during the 2010s at RWTH Aachen University, Germany. These examples illustrate the asynchronous beginnings of similar developments, and also contextualize differences in disciplinary habitus and pedagogical approaches between Sheffield, where research impulses stemmed from within the Architectural Humanities, and Aachen with its strong tradition as a technical university.
This paper presents a numerical procedure for reliability analysis of thin plates and shells with respect to plastic collapse or to inadaptation. The procedure involves a deterministic shakedown analysis for each probabilistic iteration, which is based on the upper bound approach and the use of the exact Ilyushin yield surface. Probabilistic shakedown analysis deals with uncertainties originated from the loads, material strength and thickness of the shell. Based on a direct definition of the limit state function, the calculation of the failure probability may be efficiently solved by using the First and Second Order Reliability Methods (FORM and SORM). The problem of reliability of structural systems (series systems) is handled by the application of a special technique which permits to find all the design points corresponding to all the failure modes. Studies show, in this case, that it improves considerably the FORM and SORM results.
Twee Kanten van één Medaille
(2020)
Tristan und Isolde, Samson und Dalila, Capriccio : 3D illustration for posters of Cologne Opera
(2009)
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) today are widely used for the investigation of normal electromechanical cardiac function, of cardiac medication and of mutations. Computational models are thus established that simulate the behavior of this kind of cells. This section first motivates the modeling of hiPS-CM and then presents and discusses several modeling approaches of microscopic and macroscopic constituents of human-induced pluripotent stem cell-derived and mature human cardiac tissue. The focus is led on the mapping of the computational results one can achieve with these models onto mature human cardiomyocyte models, the latter being the real matter of interest. Model adaptivity is the key feature that is discussed because it opens the way for modeling various biological effects like biological variability, medication, mutation and phenotypical expression. We compare the computational with experimental results with respect to normal cardiac function and with respect to inotropic and chronotropic drug effects. The section closes with a discussion on the status quo of the specificity of computational models and on what challenges have to be solved to reach patient-specificity.
Many biped robots deploy a form of gait that follows the zero moment point (ZMP) approach, that is, the robot is in a stable position at any point in time. This requires the robot to be fully actuated. While very stable, the draw-backs of this approach are a fairly slow gait and high energy consumption. An alternative approach is the so-called passive-dynamic walking, where the gait makes use of the inertia and dynamic stability of the robot. In this paper we describe our ongoing work of combining the principles of passive-dynamic walking on the fully-actuated biped robot Nao, which is also deployed for robotic soccer applications. We present a simple controller that allows the robot to stably rock sidewards, showing a closed limit-cycle. We discuss first results of superimposing a forward motion on the sidewards motion. Based on this we expect to endow the Nao with a fast, robust, and stable passive-dynamic walk on the fully-actuated Nao in the future.