Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles
- A new approach for a label-free electrical detection of DNA hybridization and denaturation using an array of individually addressable field-effect nanoplate SOI (silicon-on-insulator) capacitors functionalized with gold nanoparticles is presented. By using a constant-capacitance measuring setup in a differential mode, signal changes of ∼110 mV and ∼70 mV have been registered after the DNA hybridization and denaturation events, respectively.
| Author: | Maryam H. Abouzar, A. M. Pedraza, Michael Josef SchöningORCiD, Arshak PoghossianORCiD |
|---|---|
| DOI: | https://doi.org/10.1016/j.proeng.2010.09.259 |
| ISSN: | 1877-7058 |
| Parent Title (English): | Procedia Engineering |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2010 |
| Date of the Publication (Server): | 2012/12/18 |
| Volume: | 5 |
| First Page: | 918 |
| Last Page: | 921 |
| Note: | Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria |
| Link: | https://doi.org/10.1016/j.proeng.2010.09.259 |
| Zugriffsart: | campus |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
