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Myocardial T2 mapping free of distortion using susceptibility-weighted fast spin-echo imaging: A feasibility study at 1.5 T and 3.0 T

  • This study demonstrates the feasibility of applying free-breathing, cardiac-gated, susceptibility-weighted fast spin-echo imaging together with black blood preparation and navigator-gated respiratory motion compensation for anatomically accurate T₂ mapping of the heart. First, T₂ maps are presented for oil phantoms without and with respiratory motion emulation (T₂ = (22.1 ± 1.7) ms at 1.5 T and T₂ = (22.65 ± 0.89) ms at 3.0 T). T₂ relaxometry of a ferrofluid revealed relaxivities of R2 = (477.9 ± 17) mM⁻¹s⁻¹ and R2 = (449.6 ± 13) mM⁻¹s⁻¹ for UFLARE and multiecho gradient-echo imaging at 1.5 T. For inferoseptal myocardial regions mean T₂ values of 29.9 ± 6.6 ms (1.5 T) and 22.3 ± 4.8 ms (3.0 T) were estimated. For posterior myocardial areas close to the vena cava T₂-values of 24.0 ± 6.4 ms (1.5 T) and 15.4 ± 1.8 ms (3.0 T) were observed. The merits and limitations of the proposed approach are discussed and its implications for cardiac and vascular T₂-mapping are considered.

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Author:Uwe Heinrichs, Jane F. Utting, Tobias Frauenrath, Fabian Hezel, Gabriele A. Krombach, Michael A. J. Hodenius, Sebastian Kozerke, Thoralf Niendorf
DOI:https://doi.org/10.1002/mrm.22054
ISSN:1522-2594
Parent Title (English):Magnetic Resonance in Medicine
Publisher:Wiley-Liss
Place of publication:New York
Document Type:Article
Language:English
Year of Completion:2009
Date of first Publication:2009/06/12
Date of the Publication (Server):2024/06/21
Volume:62
Issue:3
First Page:822
Last Page:828
Link:https://doi.org/10.1002/mrm.22054
Zugriffsart:campus
Institutes:FH Aachen / Fachbereich Elektrotechnik und Informationstechnik
collections:Verlag / Wiley-Liss