Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles
- A new approach for a label-free electrical detection of DNA hybridization and denaturation using an array of individually addressable field-effect nanoplate SOI (silicon-on-insulator) capacitors functionalized with gold nanoparticles is presented. By using a constant-capacitance measuring setup in a differential mode, signal changes of ∼110 mV and ∼70 mV have been registered after the DNA hybridization and denaturation events, respectively.
Author: | Maryam H. Abouzar, A. M. Pedraza, Michael Josef SchöningORCiD, Arshak PoghossianORCiD |
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DOI: | https://doi.org/10.1016/j.proeng.2010.09.259 |
ISSN: | 1877-7058 |
Parent Title (English): | Procedia Engineering |
Publisher: | Elsevier |
Place of publication: | Amsterdam |
Document Type: | Article |
Language: | English |
Year of Completion: | 2010 |
Volume: | 5 |
First Page: | 918 |
Last Page: | 921 |
Note: | Eurosensor XXIV Conference, 5-8 September 2010, Linz, Austria |
Link: | https://doi.org/10.1016/j.proeng.2010.09.259 |
Zugriffsart: | weltweit |
Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
FH Aachen / INB - Institut für Nano- und Biotechnologien | |
collections: | Verlag / Elsevier |
Licence (German): | Creative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung |